Staining test control substance, staining test slide prepared using the same, staining test control substance preparation kit, and method for manufacturing staining test control substance

By preparing a control substance containing target molecules, negatively charged molecules, and binding substances, the problems of complex slide fabrication and peeling were solved, enabling simple and stable preparation of control substances and high-precision inspection.

CN122122464APending Publication Date: 2026-05-29HITACHI HIGH TECH CORP
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
HITACHI HIGH TECH CORP
Filing Date
2024-10-11
Publication Date
2026-05-29

AI Technical Summary

Technical Problem

In the existing technology, the preparation of glass slides for control tests is complicated, and it is difficult to prepare control substances easily. In addition, the control substances are easily peeled off from the glass slides in automatic staining devices, which affects the accuracy of the examination.

Method used

A control substance containing a target molecule, a negatively charged molecule, and a binding substance is prepared by protein aggregation and chemical modification. The negatively charged control substance is then attached to a glass slide to form a stable binding.

Benefits of technology

It enables the simple preparation of control substances, ensuring that they are not easily peeled off from the slide in the automated staining device, thus improving the accuracy management of the inspection.

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Abstract

In a control substance used in a control test in a staining examination, a slide prepared using the same, and a manufacturing method thereof, in order to provide a control substance capable of being easily prepared, a slide prepared using the same, the following configuration is adopted. A control substance for staining examination, comprising a target molecule that specifically binds to a substance contained in a staining reagent, a negatively charged charged molecule, and a binding substance that binds the target molecule and the charged molecule.
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