A pharmaceutical composition containing thymol and its application in oral health

By combining thymol and gallic acid with other natural compounds, the limited efficacy of treatments for oral ulcers and periodontitis has been addressed, resulting in faster ulcer healing and reduced inflammation, thus providing a more effective treatment option.

CN122124023APending Publication Date: 2026-06-02NANJING MUCOSA TECH CO LTD
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Patent Information

Application Number
CN202610499698.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-23
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing treatments for oral ulcers and periodontitis have limitations such as limited efficacy, high risk of recurrence, inability to fully restore periodontal tissues, and lack of specific drugs.

Method used

A pharmaceutical composition of thymol and gallic acid, combined with other natural polyhydroxy compounds such as asiaticoside and resveratrol, forms a compound solution for topical treatment of oral ulcers and periodontitis.

Benefits of technology

It significantly promoted the healing of oral ulcers and periodontitis, reduced the ulcer area, lowered the level of inflammatory factors, and improved the treatment effect. In particular, the combination of thymol and gallic acid showed the strongest synergistic effect.

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Abstract

This invention relates to a pharmaceutical composition containing thymol and its application. The solution uses water as a solvent and contains thymol and gallic acid. Specifically, the thymol content is 0.05-1 part, the gallic acid content is 1-20 parts, and the water content is 1000 parts; preferably, the thymol content is 0.1-0.5 parts, the gallic acid content is 5-15 parts, and the water content is 1000 parts; more preferably, the thymol content is 0.16 parts, the gallic acid content is 10 parts, and the water content is 1000 parts. The solution may further contain a solubilizer such as PEG-40 hydrogenated castor oil. This invention can be used to prepare pharmaceuticals, medical devices, or other oral care products for treating oral ulcers and periodontitis.
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Citation Information

Patent Citations

  • Preparation method and application of orally disintegrating tablet for treating oral ulcer

    CN118021746A

  • Preparation method and application of micellar preparation containing thymol and its derivatives

    CN118084849B