Mass spectrometer with easy sample introduction

Abstract

This application provides a mass spectrometer for easy sample loading, including a main body. A sample loading turntable is located on one side of the main body, below the sampling mechanism. The turntable includes a turntable, a sample placement tube, and multiple sets of rollers arranged in a ring at equal intervals along the outer edge of the turntable; and multiple sets of horizontal limiting components arranged in a ring at equal intervals in the middle of the sample placement tube. This application utilizes multiple sets of elastically arranged rollers arranged in a ring in the middle of the sample placement tube to fix sample vials of different diameters. A placement plate is elastically provided at the bottom of the sample placement tube, and the placement plate moves downwards via a locking mechanism. When placing sample vials of different heights, pressing the placement plate downwards ensures that the mouth height of all sample vials of different heights remains consistent. After sample loading, a release component releases the locking mechanism from the placement plate, allowing the placement plate to elastically return to its original position, facilitating repeated use and improving the practicality of the mass spectrometer.

Description

Technical Field

[0001] This invention relates to the field of mass spectrometers, and more specifically, to a mass spectrometer that facilitates sample introduction. Background Technology

[0002] A mass spectrometer is a precision scientific instrument used to analyze and identify the composition and structure of compounds. Its working principle is based on ionizing molecules or atoms in a sample into charged particles (ions), and then separating them in a vacuum environment using electric and magnetic fields according to the mass-to-charge ratio (mass to charge ratio). Finally, the relative abundance of each ion is recorded by a detector. It has extremely high sensitivity and accuracy and is widely used in fields such as chemistry, biology, pharmacy, and environmental monitoring. It can be used to determine molecular weight, resolve molecular structure, identify isotopic composition, and quantitatively analyze specific components in complex mixtures.

[0003] When using a mass spectrometer for detection, a sample introduction device is usually selected to deliver the sample into the mass spectrometer for detection. A common example is the rotary table sample introduction device, which places the sample to be detected in a ring on the rotary table and rotates the sample sequentially to be sampled for detection. Currently, the sample introduction rotary tables of mass spectrometers commonly available on the market can only accommodate sample bottles of a single size, which has poor applicability. When it is necessary to accommodate a batch of sample bottles of different heights or widths, it is often necessary to change the rotary table, which reduces the practicality of the mass spectrometer.

[0004] Therefore, we made improvements and proposed a mass spectrometer that facilitates sample introduction. Summary of the Invention

[0005] The purpose of this invention is to address the problem that currently available mass spectrometer sample inlet turntables can only accommodate sample vials of a single size, resulting in poor applicability. When it is necessary to accommodate a batch of sample vials of different heights or diameters, the turntable often needs to be replaced, which reduces the practicality of the mass spectrometer.

[0006] To achieve the above-mentioned objectives, the present invention provides a mass spectrometer that facilitates sample introduction, thereby improving the aforementioned problems.

[0007] The application is as follows:

[0008] A mass spectrometer for easy sample introduction includes a main body, a sampling mechanism disposed on one side of the main body, and a sample loading turntable disposed on the other side of the main body below the sampling mechanism. The sample loading turntable includes:

[0009] The turntable is mounted on the machine body and rotates intermittently via a drive mechanism;

[0010] Sample tubes are arranged in multiple sets, equidistantly in a ring, along the outer edge of the turntable.

[0011] A horizontal limiting component is provided, with multiple sets installed in a ring at equal intervals in the middle of the sample tube. The horizontal limiting component includes a roller that is horizontally mounted on the sample tube and elastically installed thereon. The inner end of the roller is in contact with the sample bottle.

[0012] A vertical limiting component is slidably disposed at the bottom of the sample placement cylinder, including a placement plate elastically disposed at the bottom of the inner cavity of the sample placement cylinder, and a clip and mechanism for limiting the downward movement of the placement plate are installed on the side of the sample placement cylinder;

[0013] The release component, located on the machine body, is used to release the restriction of the card and mechanism on the placement plate when the sample bottle is placed or removed into the sample cylinder, so that the placement plate can be elastically reset.

[0014] As a preferred technical solution of this application, the outer edge of the turntable is provided with a set of sample inlets at equal intervals in a ring shape, the top outer edge of the sample tube has a mounting plate, the mounting plate is installed at the bottom of the turntable, and the top of the sample tube is adapted to be inserted into the sample inlet.

[0015] As a preferred technical solution of this application, the horizontal limiting component further includes a first vertical plate fixed in a ring at equal intervals on the mounting plate, a guide seat is linearly installed on the first vertical plate, and a set of movable openings are opened in a ring at equal intervals in the middle of the sample placement cylinder. The roller is installed at the inner end of the guide seat and extends into the sample placement cylinder through the movable openings.

[0016] As a preferred technical solution of this application, a second vertical plate parallel to the first vertical plate is fixed on the mounting plate, a first guide rod is fixed between the second vertical plate and the first vertical plate, and the inner end of the guide seat is inserted and connected to the first guide rod and a first spring is fixed between the guide seat and the first vertical plate.

[0017] As a preferred technical solution of this application, the vertical limiting component includes a support base fixedly installed at the bottom end of the sample placement cylinder, and a second spring is fixed between the placement plate and the support base.

[0018] As a preferred technical solution of this application, the card and mechanism include a rack fixed to the outside of the placement plate, a set of card slots are vertically and equidistantly opened on the rack, the top inner wall of the card slot is inclined and the bottom inner wall is horizontal, and a card block adapted to the card slot is elastically provided on the outside of the sample placement cylinder.

[0019] As a preferred technical solution of this application, a limiting groove is provided in the middle of the sample placement cylinder, and a connecting block located in the limiting groove is fixed between the rack and the placement plate.

[0020] As a preferred technical solution of this application, a support plate is vertically fixed on the mounting plate, a telescopic sleeve is installed at the bottom of the support plate, and the locking block is fixed to the telescopic end of the telescopic sleeve and a third spring is fixed between the locking block and the outer end of the telescopic sleeve.

[0021] As a preferred technical solution of this application, the release component includes a second guide rod fixed to the outer end of the telescopic sleeve. The second guide rod is inserted and connected to the bottom of the support plate. A slider is installed at the outer end of the second guide rod. An annular slide is installed on the body. The annular slide has a first arc-shaped groove for the card block to be inserted into the card slot and a second arc-shaped groove for the card block to be separated from the card slot. The slider slides in the first arc-shaped groove and the second arc-shaped groove.

[0022] As a preferred technical solution of this application, the machine body is equipped with a barrier adapted to the turntable, and the annular slide is fixed in the middle of the inner wall of the barrier.

[0023] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0024] In the scheme of this application:

[0025] This application utilizes multiple sets of elastically arranged rollers arranged in a ring in the middle of the sample placement tube to fix sample bottles of different diameters. A placement plate is elastically provided at the bottom of the sample placement tube, and this plate moves downwards via a locking mechanism. When placing sample bottles of different heights, pressing the placement plate downwards ensures that the bottle opening height of all sample bottles of different heights remains consistent. After sample loading is complete, the release component releases the locking mechanism from the placement plate, allowing it to elastically return to its original position, facilitating repeated use and improving the practicality of the mass spectrometer. Attached Figure Description

[0026] Figure 1 A schematic diagram of the overall structure of the mass spectrometer for easy sample introduction provided in this application;

[0027] Figure 2 A schematic diagram of the separation of the turntable and the enclosure of the mass spectrometer provided in this application for facilitating sample introduction;

[0028] Figure 3 A schematic diagram of the structure above the turntable of the mass spectrometer provided in this application for facilitating sample introduction;

[0029] Figure 4 A schematic diagram of the bottom structure of the sample tube of the mass spectrometer for easy sample introduction provided in this application;

[0030] Figure 5 A schematic diagram of the internal structure of the sample tube of the mass spectrometer for easy sample introduction provided in this application;

[0031] Figure 6 A schematic diagram of the rack and clamp of the mass spectrometer for easy sample introduction provided in this application;

[0032] Figure 7 A schematic diagram of the enclosure of the mass spectrometer for facilitating sample introduction provided in this application.

[0033] The image shows:

[0034] 100. Body; 101. Sampling mechanism; 102. Driving component;

[0035] 200. Rotary table; 201. Inlet;

[0036] 300. Sample holder; 301. Mounting plate; 302. Movable opening; 303. Limiting groove;

[0037] 400. Roller; 401. First vertical plate; 402. Guide seat; 403. Second vertical plate; 404. First guide rod; 405. First spring;

[0038] 500. Shelf; 501. Support base; 502. Second spring; 503. Rack; 504. Slot; 505. Block; 506. Connecting block; 507. Support plate; 508. Telescopic sleeve; 509. Third spring;

[0039] 600, Second guide rod; 601, Slider; 602, Annular slide block; 603, First arc groove; 604, Second arc groove; 605, Enclosure. Detailed Implementation

[0040] To enable those skilled in the art to better understand the present invention, the technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort should fall within the scope of protection of the present invention.

[0041] The present invention will be further described below with reference to embodiments.

[0042] Example: Refer to Figures 1 to 7A mass spectrometer for easy sample introduction includes a body 100, a sampling mechanism 101 on one side of the body 100, and a sample loading turntable located below the sampling mechanism 101 on another side of the body 100. The sample loading turntable includes a turntable 200, a sample container 300, a horizontal limiting component, a vertical limiting component, and a release component. The turntable 200 is intermittently rotated on the body 100 by a drive component 102, used to intermittently move human sample vials placed in the sample container 300 to the sampling mechanism 101. Sampling is completed at the sampling point. Sample cylinders 300 are provided in multiple sets and are installed in a ring at equal intervals on the outer edge of turntable 200. Preferably, a set of sample inlets 201 are provided in a ring at equal intervals on the outer edge of turntable 200. The size of the sample inlet 201 is the same as the diameter of the sample cylinder 300. The top outer edge of the sample cylinder 300 has a mounting plate 301. The mounting plate 301 is installed on the bottom of turntable 200 by fasteners for easy disassembly and assembly. The top of the sample cylinder 300 is adapted to be inserted into the sample inlet 201 for easy insertion of sample bottles.

[0043] The horizontal limiting components are arranged in multiple sets and are equidistantly installed in a ring at the center of the sample cylinder 300. These components are used to horizontally limit the position of the sample and adapt to sample bottles of different sizes. The horizontal limiting components include rollers 400 that are horizontally and elastically mounted on the sample cylinder 300, with the inner end of each roller 400 contacting the sample bottle. The components also include a first vertical plate 401 fixed equidistantly in a ring on the mounting plate 301. A guide seat 402 is linearly mounted on the first vertical plate 401. A set of movable openings 302 are equidistantly opened in a ring at the center of the sample cylinder 300. The rollers 400 are installed inside the guide seats 402 and extend into the sample cylinder 300 through the movable openings 302. Preferably, the guide seat 402 is a U-shaped seat, and the rollers 400 are rotatably mounted on the openings of the U-shaped seat. The roller 400 at the mouth end can rotate, which reduces the frictional resistance of the roller 400 to the sample bottle when it is inserted into the sample tube 300. A second vertical plate 403 parallel to the first vertical plate 401 is fixed on the mounting plate 301. A first guide rod 404 is fixed between the second vertical plate 403 and the first vertical plate 401. The inner end of the guide seat 402 is inserted and connected to the first guide rod 404 and a first spring 405 is fixed between the guide seat 402 and the first vertical plate 401. The first guide rod 404 allows the roller 400 to move linearly with the U-shaped seat. The elastic deformation of the first spring 405 ensures that the roller 400 can make precise contact with the sample bottle and limit its horizontal movement when facing sample bottles of different thicknesses placed in the sample tube 300.

[0044] The vertical limiting component is slidably disposed at the bottom of the sample placement cylinder 300, including a placement plate 500 elastically disposed at the bottom of the inner cavity of the sample placement cylinder 300. A clip and mechanism for limiting the downward movement of the placement plate 500 are installed on the side of the sample placement cylinder 300. The vertical limiting component includes a support base 501 fixedly installed at the bottom end of the sample placement cylinder 300. A second spring 502 is fixed between the placement plate 500 and the support base 501. The support of the second spring 502 allows the placement plate 500 to be located in the middle of the sample placement cylinder 300 in the initial state. When placing a tall sample bottle, pressing the sample bottle causes the placement plate 500 to move downward, the second spring 502 is compressed, and the clip and mechanism restrict the placement plate 500 to return to its original position. That is, the sample bottle can be pressed down to a height that is convenient for the sampling mechanism 101 to take samples. The structure is simple and the operation is convenient.

[0045] The mechanism includes a rack 503 fixed to the outside of the placement plate 500. A set of slots 504 are vertically and equidistantly provided on the rack 503. The top inner wall of the slots 504 is inclined and the bottom inner wall is horizontal. A block 505 adapted to the slots 504 is elastically provided on the outside of the sample cylinder 300. That is, the upper side of the block 505 has an inclined surface adapted to the top inner wall of the slots 504, and the bottom is horizontal. A limiting slot 303 is provided in the middle of the sample cylinder 300. A connecting block 506 located in the limiting slot 303 is fixed between the rack 503 and the placement plate 500. A support plate 507 is vertically fixed on the mounting plate 301. A telescopic sleeve 508 is installed at the bottom of the support plate 507. The block 505 is fixed to the telescopic end of the telescopic sleeve 508 and a third spring 509 is fixed between the block 505 and the outer end of the telescopic sleeve 508.

[0046] During the downward movement of the placement plate 500, the rack 503 moves downward synchronously with the pressing object, and the connecting block 506 slides vertically within the limiting groove 303. During this process, each slot 504 will first press down to make the locking block 505 move along the telescopic sleeve 508 and separate from the slot 504. When the slot 504 and the locking block 505 are aligned again, the locking block 505 will re-enter the slot 504 under the action of the third spring 509. Then, when the sample bottle is pressed down to a height that facilitates the sampling mechanism 101 to take samples, the sample bottle is released, and the locking block is inserted into the slot 504. Since the bottom of the locking block and the bottom of the slot 504 are the same horizontal plane, the locking block 505 fixes the height of the rack 503 and the placement plate 500, preventing the sample bottle from resetting under the action of the second spring 502.

[0047] The release component, mounted on the body 100, releases the restriction of the locking mechanism on the placement plate 500 when the sample vial is placed into the sample cylinder 300, allowing the placement plate 500 to elastically reset. Specifically, the release component includes a second guide rod 600 fixed to the outer end of the telescopic sleeve 508. The second guide rod 600 is inserted into the bottom of the support plate 507. A slider 601 is mounted on the outer end of the second guide rod 600. An annular slide block 602 is mounted on the body 100. The annular slide block 602 has a first arc-shaped groove 603 for engaging the locking block 505 into the locking slot 504 and a second arc-shaped groove 604 for separating the locking block 505 from the locking slot 504. The slider 601 slides within the first arc-shaped groove 603 and the second arc-shaped groove 604. Figure 7 As shown, the second arc-shaped groove 604 protrudes outward from the first arc-shaped groove 603. When the slider 601 is located in the first arc-shaped groove 603, the positions of the second guide rod 600 and the telescopic sleeve 508 are fixed, and the locking block 505 is locked in the locking groove 504. When the slider 601 enters the first arc-shaped groove 603 and is located at the outermost end of the first arc-shaped groove 603, the slider 601, along with the second guide rod 600, the telescopic sleeve 508, and the locking block 505, separates from the locking groove 504. At this time, under the action of the second spring 502, the placement plate 500 resets the sample bottle. During the reset process, the roller 400 provides frictional resistance to the sample bottle to ensure its upward stability.

[0048] The body 100 is equipped with a barrier 605 that is compatible with the turntable 200, and the annular slide 602 is fixed in the middle of the inner wall of the barrier 605.

[0049] The working principle of the mass spectrometer for easy sample introduction provided in this application is as follows:

[0050] When placing taller and thicker sample vials, the sample vials are placed into the sample placement cylinder 300. The body of the sample vial presses against the roller 400, which in turn presses against the first spring 405. The elastic force of the first spring 405 ensures that the roller 400 is in close contact with the sample vial, limiting the horizontal movement of the sample vial. Then, the sample vial is pressed down, causing the sample vial to press down the placement plate 500. The rack 503 moves down synchronously with the pressing plate. During this process, each slot 504 presses down on the locking block 505, causing the locking block 505 to move along the telescopic sleeve 508. When the sample vial is pressed down to a height suitable for sampling by the sampling mechanism 101, the sample vial is released, and the locking block 505 re-engages in the slot 504. Since the bottom inner wall of the slot 504 is horizontal, and the locking block 505... With the bottom surface being horizontal, the locking block 505 fixes the height of the placement plate 500 in this state, preventing the sample bottle from resetting under the action of the second spring 502. When the sample bottle, after being extracted by the sampling mechanism 101, moves with the turntable 200 to the second arc groove 604, the slider 601 enters the second arc groove 604, driving the second guide rod 600, the telescopic sleeve 508, and the locking block 505 to move away from the rack 503 simultaneously. When it moves to the outermost end of the second arc groove 604, the locking block 505 separates from the groove 504, thus restricting the contact of the second spring 502. Under the action of the second spring 502, the placement plate 500 resets to its initial height, making it easy to repeat the above operation of picking up and placing the sample bottle at the next position.

[0051] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0052] Obviously, the embodiments described above are merely some embodiments of the present invention, not all embodiments. The accompanying drawings show preferred embodiments of the present invention, but do not limit the patent scope of the present invention. The present invention can be implemented in many different forms; rather, these embodiments are provided to provide a more thorough and complete understanding of the disclosure of the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing specific embodiments, or make equivalent substitutions for some of the technical features. Any equivalent structures made using the content of this specification and drawings, directly or indirectly applied to other related technical fields, are similarly within the patent protection scope of this invention.

Claims

1. A mass spectrometer for easy sample introduction, comprising a body (100), a sampling mechanism (101) disposed on one side of the body (100), and a sample loading turntable disposed on one side of the body (100) below the sampling mechanism (101), characterized in that, The sample loading turntable includes: A turntable (200) is mounted on the body (100) by intermittent rotation via a drive unit (102); Sample tubes (300) are provided in multiple sets and are installed in a ring at equal intervals along the outer edge of the turntable (200); A horizontal limiting component is provided with multiple sets of components that are equidistantly installed in a ring at the middle of the sample tube (300). The horizontal limiting component includes rollers (400) that are horizontally mounted on the sample tube (300) and whose inner ends are in contact with the sample bottle. A vertical limiting component is slidably disposed at the bottom of the sample placement cylinder (300), including a placement plate (500) elastically disposed at the bottom of the inner cavity of the sample placement cylinder (300), and a card and mechanism for limiting the downward movement of the placement plate (500) are installed on the side of the sample placement cylinder (300). The release component, located on the body (1), is used to release the card and mechanism from the restriction of the placement plate (500) when the sample bottle is placed in the sample tube (300), so that the placement plate (500) can be elastically reset.

2. The mass spectrometer for easy sample introduction according to claim 1, characterized in that, The outer edge of the turntable (200) is provided with a set of sample inlets (201) at equal intervals in a ring. The top outer edge of the sample tube (300) has a mounting plate (301). The mounting plate (301) is installed at the bottom of the turntable (200). The top of the sample tube (300) is adapted to be inserted into the sample inlet (201).

3. A mass spectrometer for easy sample introduction according to claim 2, characterized in that, The horizontal limiting component also includes a first vertical plate (401) fixed in a ring at equal intervals on the mounting plate (301). A guide seat (402) is linearly installed on the first vertical plate (401). A set of movable openings (302) are opened in a ring at equal intervals in the middle of the sample cylinder (300). The roller (400) is installed at the inner end of the guide seat (402) and extends into the sample cylinder (300) through the movable openings (302).

4. A mass spectrometer for easy sample introduction according to claim 3, characterized in that, A second vertical plate (403) parallel to the first vertical plate (401) is fixed on the mounting plate (301). A first guide rod (404) is fixed between the second vertical plate (403) and the first vertical plate (401). The inner end of the guide seat (402) is inserted and connected to the first guide rod (404) and a first spring (405) is fixed between the guide seat (402) and the first vertical plate (401).

5. A mass spectrometer for easy sample introduction according to claim 4, characterized in that, The vertical limiting component includes a support base (501) fixedly installed at the bottom of the sample cylinder (300), and a second spring (502) is fixed between the sample plate (500) and the support base (501).

6. A mass spectrometer for easy sample introduction according to claim 5, characterized in that, The card and mechanism include a rack (503) fixed to the outside of the placement plate (500), and a set of card slots (504) are provided vertically and equidistantly on the rack (503). The top inner wall of the card slot (504) is inclined and the bottom inner wall is horizontal. The outer side of the sample cylinder (300) is elastically provided with a card block (505) that is adapted to the card slot (504).

7. A mass spectrometer for easy sample introduction according to claim 6, characterized in that, A limiting slot (303) is provided in the middle of the sample tube (300), and a connecting block (506) located in the limiting slot (303) is fixed between the rack (503) and the placement plate (500).

8. A mass spectrometer for easy sample introduction according to claim 7, characterized in that, A support plate (507) is vertically fixed on the mounting plate (301). A telescopic sleeve (508) is installed at the bottom of the support plate (507). The locking block (505) is fixed to the telescopic end of the telescopic sleeve (508) and a third spring (509) is fixed between the locking block (505) and the outer end of the telescopic sleeve (508).

9. A mass spectrometer for easy sample introduction according to claim 8, characterized in that, The release assembly includes a second guide rod (600) fixed to the outer end of the telescopic sleeve (508). The second guide rod (600) is inserted and connected to the bottom of the support plate (507). A slider (601) is installed on the outer end of the second guide rod (600). An annular slide (602) is installed on the body (100). The annular slide (602) has a first arc-shaped groove (603) for engaging the locking block (505) into the locking groove (504) and a second arc-shaped groove (604) for separating the locking block (505) from the locking groove (504). The slider (601) slides within the first arc-shaped groove (603) and the second arc-shaped groove (604).

10. A mass spectrometer for easy sample introduction according to claim 9, characterized in that, The body (100) is equipped with a barrier (605) adapted to the turntable (200), and the annular slide (602) is fixed in the middle of the inner wall of the barrier (605).

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