Conductive hydrogel microneedle working electrode, preparation method thereof and application of conductive hydrogel microneedle wearable biosensor in potassium ion detection

Abstract

The application provides a conductive hydrogel microneedle working electrode and a preparation method thereof and application of the conductive hydrogel microneedle wearable biosensor in potassium ion detection, and belongs to the technical field of wearable sensing analysis and detection, and is used for dynamically and real-timely monitoring concentration changes of potassium ions in the body, covering the concentration change range of K + in normal human bodies and unbalanced patient bodies. A double-network conductive hydrogel microneedle working electrode is prepared by using a hydrogel material with a double bond and a conductive polymer as a matrix, doping Prussian blue nanocrystals and then performing ultraviolet crosslinking. The Prussian blue nanocrystals can specifically react with K + and accompany electron transfer, so that the current response changes with the concentration change of K + . After a microneedle three-electrode system is constructed, the wearable biosensor is prepared by connecting a micro work station, the smart phone is connected through Bluetooth, real-time monitoring of the concentration of K + in the body is realized on the mobile phone, and a new method is provided for real-time monitoring of the concentration of K + in the body of a clinical patient and a healthy person.

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