Injection device for determining the location of an esophageal cancer lesion

Abstract

The present application relates to the technical field of esophageal cancer determination, and particularly relates to an injection device for esophageal cancer lesion position determination, aiming at the problem that the existing device cannot dynamically adjust injection parameters according to lesion ranges, the injection device for esophageal cancer lesion position determination comprises a pipeline, the rear end of the pipeline is connected with a handle, further comprises a bite assembly, a multi-needle injection mechanism and a depth control mechanism; the bite assembly is movably sleeved on the pipeline, is used for adapting to different esophageal lesion positions, and is fixed; the multi-needle injection mechanism is arranged at the front end of the pipeline, is used for forming linear mark points at the edge of the esophageal lesion area; the depth control mechanism is arranged between the multi-needle injection mechanism and the handle, and is used for controlling the injection depth. The multi-needle injection mechanism comprises a tracer cavity, a plurality of injection needles and an angle adjusting assembly. The injection device for esophageal cancer lesion position determination in the present application can adopt synchronous injection of the plurality of injection needles, and can also quickly aim the injection needles at the target direction.

Description

Technical Field

[0001] This invention relates to the field of esophageal cancer diagnosis technology, and in particular to an injection device for determining the location of esophageal cancer lesions. Background Technology

[0002] The high incidence of esophageal cancer and the importance of early diagnosis: As a common malignant tumor of the digestive tract, the incidence of esophageal cancer is closely related to lifestyle habits (such as smoking and drinking) and dietary structure. Early-stage esophageal cancer patients may only present with atypical symptoms such as a feeling of obstruction or food retention when swallowing, which are easily overlooked. By the time it progresses to difficulty swallowing or hoarseness, it is often already in an advanced stage. Therefore, early and accurate diagnosis is crucial to improving patient survival rates, and accurate determination of the lesion location is the core of diagnosis.

[0003] Traditional injection devices are limited in function, relying heavily on conventional syringes. Their capabilities are confined to single-dose injections, making it impossible to dynamically adjust injection parameters (such as dosage and range) based on the extent of the lesion. Furthermore, manual operation can easily lead to injection site deviations, affecting diagnostic accuracy. For different lesion extents (such as diffuse versus focal lesions), existing devices lack flexible adjustment mechanisms, impacting diagnostic versatility. Current iodine staining requires manual spraying of iodine, resulting in low efficiency and poor uniformity, easily leading to uneven staining and affecting diagnostic results. In addition, traditional devices cannot synchronize staining with image localization, limiting their clinical application value. Summary of the Invention

[0004] To address the problems existing in the prior art, this invention provides an injection device for determining the location of esophageal cancer lesions. The core of this invention lies in providing a determination device that integrates active fixation, multi-needle precision injection, and depth control, aiming to overcome the positioning deviation of traditional handheld injection and provide an objective and repeatable physical calibration method for accurately defining the extent of esophageal cancer lesions.

[0005] Specifically, on the one hand, the occlusal component at the front end of the device provides temporary stable fixation within the esophageal lumen, eliminating the impact of operational vibrations and laying the foundation for precise injection. Building upon this, a multi-needle injection mechanism can simultaneously create continuous or equidistant linear markers at the edge of the lesion area in a single operation, dynamically adapting to different lesion morphologies (such as focal or diffuse). On the other hand, the coordinated use of angle adjustment and depth control mechanisms allows for rapid and flexible aiming of the injection needle at the target location and control of the marking depth, greatly improving operational flexibility and surgical field visibility.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is as follows: This application provides an injection device for determining the location of esophageal cancer lesions, including a tubing with a handle connected to the rear end of the tubing, and also including an occlusal component, a multi-needle injection mechanism, and a depth control mechanism; the occlusal component is movably sleeved on the tubing to adapt to different esophageal lesion locations and a fixing device; the multi-needle injection mechanism is located at the front end of the tubing to form linear markers at the edge of the esophageal lesion area; the depth control mechanism is located between the multi-needle injection mechanism and the handle to control the injection depth.

[0007] Furthermore, the occlusal assembly includes a mouth baffle, an occlusal airbag, and a supplementary airbag; the mouth baffle is movably fitted onto the pipe; the occlusal airbag is located at the front of the mouth baffle; and the supplementary airbag is located at the rear of the mouth baffle to inflate the occlusal airbag.

[0008] Furthermore, the multi-needle injection mechanism includes a tracer chamber, multiple injection needles, and an angle adjustment assembly; the tracer chamber is connected to the front end of the tubing and is used to contain the tracer; the multiple injection needles are movably mounted on the front end of the tracer chamber and are all in communication with the tracer chamber, and are used to inject the tracer at the edge of the esophageal lesion area; the angle adjustment assembly is connected to each injection needle and is used to adjust the angle of each injection needle in the vertical direction.

[0009] Furthermore, the angle adjustment assembly includes a fixing frame and a gear set; the fixing frame is rotatably connected to the front end of the tracer chamber for mounting the injection needle; the gear set is disposed between the tracer chamber and the fixing frame for adjusting the angle of the fixing frame.

[0010] Furthermore, the tracer chamber includes a first chamber, a second chamber, and a third chamber; the first chamber has an annular structure and is connected to the front end of the pipe for containing indocyanine green solution; the second chamber has a U-shaped structure and is connected to the front end of the first chamber for containing methylene blue solution; the third chamber is disposed between the first chamber and the second chamber, and both the first chamber and the second chamber are connected to the third chamber.

[0011] Furthermore, the injection needle is connected to the third cavity via a drug delivery tube.

[0012] Furthermore, the depth control mechanism includes multiple syringes, multiple piston plates, and multiple air guide tubes; the multiple syringes are mounted on a fixed frame with an open front end for mounting corresponding injection needles; the multiple piston plates are slidably and sealingly fitted inside the corresponding syringes, forming a sealed cavity with the rear of the syringe; each injection needle penetrates the corresponding piston plate; one end of each of the multiple air guide tubes is connected to the corresponding sealed cavity, and the other end is connected to an air pump for drawing external gas into the sealed cavity, causing the piston plate to move and controlling the insertion depth of the injection needle.

[0013] Furthermore, the injection device also includes a direction adjustment component disposed between the tracer chamber and the tubing, for adjusting the angle of the injection needle in the horizontal direction.

[0014] Furthermore, the directional adjustment assembly includes a transmission block, a torsion member, and a connecting block; the rear end of the transmission block is coaxially connected to the front end of the pipe, and a transmission channel is provided at the center of the transmission block; the rear end of the torsion member is slidably and sealed within the transmission channel; the front end of the torsion member is connected to the connecting block.

[0015] Furthermore, a rotating handle is rotatably provided at the rear end of the handle; a piston assembly is sleeved inside the rotating handle, and the piston assembly is connected to the orientation adjustment assembly through the pipe, for pressurizing the orientation adjustment assembly to rotate the injection needle.

[0016] Compared with the prior art, the beneficial effects of the present invention are: 1. By employing multiple injection needles for simultaneous injection, continuous or equidistant linear markers can be formed at the proximal or distal edge of the lesion area in a single operation, visually representing the resection boundary and significantly shortening the operation time. The angle adjustment component allows adjustment of the tilt angle of each injection needle in the vertical plane, ensuring that the needle tip is always perpendicular to the local esophageal wall surface. A gear set provides precise and stable transmission, facilitating fine-tuning and angle locking by the physician, ensuring controllable injection depth and medication retention at the target layer. The depth is precisely controlled by air pressure and air intake time, adaptable to different lesion layers. Simultaneous extension and retraction of multiple needles ensures consistent linear marker depth, avoiding blurred markings or uneven tissue damage due to depth differences. Compared to a manual push-rod structure, the pneumatic system offers faster response and more uniform force, and closed-loop feedback via a pressure sensor further enhances safety.

[0017] 2. By moderately inflating the bite balloon with supplemental air supply, the tube can be firmly clamped to prevent slippage during the operation, and the damage to teeth or gums caused by traditional rigid bite devices can be avoided. It can also adapt to different patients' oral cavity size and mouth opening. The overall axial position of the device in the esophagus is stabilized, providing a reliable reference platform for subsequent precise injection and reducing displacement errors caused by patients swallowing or breathing.

[0018] 3. The two tracers are delivered to the corresponding injection needles through the drug delivery tube, enabling zonal, time-sharing, or combined injection, leveraging the dual advantages of "staining + fluorescence" to significantly improve the detection rate of early lesions and the reliability of boundary determination.

[0019] 4. Esophageal lesions may be located at any time point, making it difficult to cover them with a single-direction injection needle. By setting the directional adjustment component between the tracer cavity and the tubing, and working with the rotating handle and piston assembly at the rear of the handle, torque is transmitted through air pressure to drive the front injection component to rotate around the tubing axis. Doctors can quickly aim the injection needle at the target location without having to rotate the entire endoscope or device body, improving operational flexibility and surgical field visibility.

[0020] 5. To address the issue of traditional handheld grips, a handheld stabilization device is added via an "engagement component," overcoming the shaking deviation inherent in traditional handheld grips.

[0021] 6. Combining traditional iodine staining with this device, the doctor first performs routine iodine staining and finds an unstained area (suspected lesion). However, the boundary of this area may be irregular and blurred. At this time, using this device, under direct endoscopic visualization, a ring of marker points is precisely injected along the edge of the unstained area. This provides a precise, stable, and image-based physical marking framework to anchor and define the extent of the lesion, thus solving three major pain points: "dynamically adjusting injection parameters (for different lesion extents)," "improving the accuracy of judgment," and "synchronizing staining (marking) with image localization." Attached Figure Description

[0022] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0023] Figure 1 This is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the internal structure of the present invention; Figure 3 This is a schematic diagram of the multi-needle injection mechanism in this invention; Figure 4 This is a schematic diagram of the mounting base in this invention; Figure 5 This is a cross-sectional view of the multi-needle injection mechanism in this invention; Figure 6 This is a schematic diagram of the angle orientation component in this invention; Figure 7 This is a schematic diagram of the rotating seat in this invention; Figure 8 This is a schematic diagram of the suction tube and air pump in this invention; Figure 9 This is a cross-sectional view of the handle in this invention; Figure 10 This is a schematic diagram of the rotating handle and piston assembly in this invention; Figure 11 This is a schematic diagram of the occlusal assembly in this invention; Figure 12 This is a schematic diagram of the fastening screw ring in this invention; Figure 13 For the present invention Figure 2 Enlarged view of point A in the middle; Figure 14 This is a schematic diagram of the injection needle in this invention; Figure 15 This is a schematic diagram of the syringe structure in this invention.

[0024] In the diagram: 1-pipe; 11-handle; 111-T-block; 2-biting assembly; 21-mouth baffle; 22-biting airbag; 23-replenishing airbag; 24-fastening nut; 25-fastening threaded ring; 26-connecting ring; 3-multi-needle injection mechanism; 31-tracer chamber; 311-first chamber; 312-second chamber; 313-third chamber; 314-connecting channel; 32-injection needle; 33-angle adjustment assembly; 331-fixed frame; 332-gear set 34-Drug delivery tube; 35-Rotating seat; 36-Mounting seat; 4-Depth control mechanism; 41-Syringe; 411-Sealed cavity; 42-Piston plate; 43-Gas delivery tube; 44-Gas delivery pump; 45-Spring; 46-Suction tube; 5-Orientation adjustment assembly; 51-Bracket; 52-Transmission block; 521-Transmission channel; 53-Torsion component; 54-Connecting block; 6-Rotating handle; 7-Piston assembly; 8-Display screen; 9-LED light; 91-Wiring; 10-Camera. Detailed Implementation

[0025] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments, and not all embodiments.

[0026] In the description of this invention, it should be understood that the terms "front", "rear", "left", "right", "upper", "lower", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0027] In the description of this application, it should also be noted that, unless otherwise expressly specified and limited, the terms "set up," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0028] Example 1 Combination Figures 1-15 As shown, the present invention provides an injection device for determining the location of esophageal cancer lesions, including a tube 1, a handle 11 connected to the rear end of the tube 1, and also including an occlusal component 2, a multi-needle injection mechanism 3, and a depth control mechanism 4; the occlusal component 2 is movably sleeved on the tube 1 to adapt to different esophageal lesion locations and to fix the device; the multi-needle injection mechanism 3 is disposed at the front end of the tube 1 to form linear marker points at the edge of the esophageal lesion area; the depth control mechanism 4 is disposed between the multi-needle injection mechanism 3 and the handle 11 to control the injection depth.

[0029] Specifically, the tube 1 serves as the structural framework and gas transmission channel for the entire device, providing rigid support to ensure stability of the front end within the esophagus. It is made of high-rigidity medical polymer and its dimensions are adapted to the endoscope's working channel. The rear end of the tube 1 is inserted into and fixed inside the handle 11, communicating with the internal cavity structure of the handle 11. The outer shell of the handle 11 is made of ABS. During operation, the tube 1 is inserted into the esophagus through the mouth to the target position. The occlusal component 2 is used to fix the device in the patient's oral cavity to prevent displacement during the procedure and to seal the oral cavity to maintain a clear operating field. The multi-needle injection mechanism 3 has multiple LED lights 9 arranged circumferentially at its front end and is equipped with a camera 10. The operation button of the camera 10 is located on the handle 11 and is electrically connected to the operation button. The multiple LED lights 9 are electrically connected to the operation button via wiring 91. The function of the multi-needle injection mechanism 3 is to inject a tracer to the edge of the esophageal cancer lesion area to create a marker.

[0030] Furthermore, the occlusal assembly 2 includes a mouth baffle 21, an occlusal airbag 22, and a supplementary airbag 23; the mouth baffle 21 is movably sleeved on the pipe 1; the occlusal airbag 22 is disposed at the front of the mouth baffle 21; and the supplementary airbag 23 is disposed at the rear of the mouth baffle 21 for inflating the occlusal airbag 22.

[0031] The occlusal component 2 is movably fitted onto the outer wall of the pipe 1 and its position is fixed by friction with the outer wall of the pipe 1. The mouth baffle 21 is elongated and adaptable to the mouth, positioned outside the lips to provide a limit, and is made of medical-grade silicone coated with rigid plastic. The rear end of the occlusal airbag 22 is fixedly welded to the mouth baffle 21 via a connecting ring 26. The occlusal airbag 22 has a hollow internal structure and is made of highly elastic medical-grade silicone, allowing its size to be adjusted to adapt to the patient's bite. The supplementary airbag 23 is cylindrical and hollow internal, with its front end fixedly welded to the mouth baffle 21 via a connecting ring 26. It is made of highly elastic medical-grade silicone and can deform when compressed. Multiple through holes are provided on the connecting ring 26, connecting the occlusal airbag 22 and the supplementary airbag 23, allowing gas from the supplementary airbag 23 to enter the occlusal airbag 22.

[0032] It should be noted that the engagement assembly 2 also includes a fastening nut 24 and a fastening ring 25. The fastening ring 25 is slidably sleeved on the pipe 1 and integrally formed with the mouth baffle 21. The outer wall of the fastening ring 25 is provided with external threads. The supplementary airbag 23 is sleeved on the fastening ring 25. The fastening nut 24 is threadedly connected to the fastening ring 25. In use, rotating the fastening nut 24 causes the fastening nut 24 to move on the fastening ring 25, thereby squeezing the supplementary airbag 23 so that the gas inside the supplementary airbag 23 enters the engagement airbag 22, thereby changing the outer diameter of the engagement airbag 22.

[0033] Furthermore, the multi-needle injection mechanism 3 includes a tracer chamber 31, multiple injection needles 32, and an angle adjustment component 33; the tracer chamber 31 is connected to the front end of the conduit 1 and is used to contain the tracer; the multiple injection needles 32 are movably mounted on the front end of the tracer chamber 31 and are all in communication with the tracer chamber 31, and are used to inject the tracer at the edge of the esophageal lesion area; the angle adjustment component 33 is connected to each injection needle 32 and is used to adjust the angle of each injection needle 32 in the vertical direction.

[0034] The rear end of the tracer chamber 31 is fixedly welded to the conduit 1 and sealed. The chamber shell is made of transparent medical-grade polymethyl methacrylate (PMMA), which is resistant to chemical corrosion. The injection needle 32 has a beveled tip and a length of 10-15 mm. Its function is to penetrate the submucosa of the esophagus and inject the tracer.

[0035] The multi-needle injection mechanism 3 also includes a mounting base 36 and a rotating base 35. The rear end of the mounting base 36 is tightly connected to the front end of the tracer chamber 31, and the LED light 9 is mounted on the front end of the mounting base 36. The rear end of the rotating base 35 is rotatably fitted inside the mounting base 36, and the front end has a receiving cavity for accommodating multiple injection needles 32 and an angle adjustment component 33. The camera 10 is mounted on the plane where the rotating base 35 and the front end of the mounting base 36 are flush.

[0036] Furthermore, the angle adjustment assembly 33 includes a fixing frame 331 and a gear set 332; the fixing frame 331 is rotatably connected to the front end of the tracer chamber 31 for mounting the injection needle 32; the gear set 332 is disposed between the tracer chamber 31 and the fixing frame 331 for adjusting the angle of the fixing frame 331.

[0037] The mounting bracket 331 is rotatably connected to the receiving cavity of the rotating seat 35, and multiple injection needles 32 are arranged sequentially from front to back in the middle of the mounting bracket 331. The gear set 332 includes two bevel gears and a micro motor for driving the mounting bracket 331 to rotate.

[0038] Furthermore, the tracer chamber 31 includes a first chamber 311, a second chamber 312, and a third chamber 313; the first chamber 311 has an annular structure and is connected to the front end of the pipe 1 for containing indocyanine green solution; the second chamber 312 has a U-shaped structure and is connected to the front end of the first chamber 311 for containing methylene blue solution; the third chamber 313 is disposed between the first chamber 311 and the second chamber 312, and both the first chamber 311 and the second chamber 312 are connected to the third chamber 313.

[0039] The first cavity 311 and the second cavity 312 are both connected to the third cavity 313 via connecting channels 314, and each connecting channel 314 is equipped with a magnetic suction valve. A water pump is installed in the third cavity 313 for drawing medicine from the first cavity 311 and the second cavity 312.

[0040] Furthermore, the injection needle 32 is connected to the third cavity 313 via the drug delivery tube 34.

[0041] The front end of each drug delivery tube 34 is connected to the rear end of the corresponding injection needle 32, and the rear end of each drug delivery tube 34 passes through the mounting base 36 and is connected to the third cavity 313. In addition, there is a remaining tube of the drug delivery tube 34 in the third cavity 313 to accommodate the angle adjustment of the injection needle 32. Furthermore, a magnetic suction valve is provided at the connection between each drug delivery tube 34 and the injection needle 32.

[0042] Furthermore, the depth control mechanism 4 includes multiple syringes 41, multiple piston plates 42, and multiple air guide tubes 43; the multiple syringes 41 are mounted on the fixing frame 331, with an open front end for mounting the corresponding injection needle 32; the multiple piston plates 42 are slidably and sealingly fitted inside the corresponding syringes 41, so that the piston plates 42 and the rear of the syringes 41 form a sealed cavity 411; each injection needle 32 passes through the corresponding piston plate 42; one end of each of the multiple air guide tubes 43 is connected to the corresponding sealed cavity 411, and the other end is connected to an air pump 44, for drawing external gas into the sealed cavity 411, causing the piston plates 42 to move and controlling the insertion depth of the injection needle 32.

[0043] The number of syringes 41 is the same as the number of injection needles 32, and the syringes 41 are fixedly mounted on the mounting base. The syringes 41 are hollow cylindrical tubes made of hard plastic. The injection needles 32 are fitted inside the syringes 41 through the piston plate 42, and the needle tips of the injection needles 32 penetrate the front end of the syringes 41. The drug delivery tube 34 penetrates the rear end of the syringes 41 and is sealed to the syringes 41. The air delivery tube 43 penetrates the rear end of the syringes 41, with one end leading to the corresponding sealed cavity 411 and each air delivery tube 43 is equipped with a magnetic suction valve. The other end penetrates the mounting base 36 and is connected to the air pump 44 inside the mounting base 36. The air pump 44 is connected to the suction tube 46 on the other side corresponding to the air delivery tube 43. The suction tube 46 is set against the side wall of the pipe 1 and leads to the handle 11 with an opening.

[0044] When in use, the air pump 44 is started to draw in or deliver air, thereby drawing in or delivering air to the sealed cavity 411 through the air tube 43, and then the piston plate 42 slides inside the syringe 41 and drives the injection needle 32 to slide back and forth.

[0045] Example 2 Based on Embodiment 1, Embodiment 2 provides a directional adjustment component 5, which allows the injection needle 32 and the camera 10 to rotate in a circular motion, thereby more quickly locating the specific location of the cancerous area in the esophagus.

[0046] The orientation adjustment assembly 5 is disposed between the tracer chamber 31 and the conduit 1 and is used to adjust the angle of the injection needle 32 in the horizontal direction. The orientation adjustment assembly 5 includes a support 51, a transmission block 52, a transmission channel 521, a torsion member 53, and a connecting block 54.

[0047] The rear end of the transmission block 52 is fixedly connected to the front end of the pipe 1 and is coaxial. The bracket 51 is sleeved inside the pipe 1 and connected to the transmission block 52. A transmission channel 521 is opened at the center of the transmission block 52. The rear end of the torsion member 53 is slidably and sealed in the transmission channel 521. The front end of the torsion member 53 is fixedly connected to the rear end of the rotating seat 35.

[0048] Furthermore, a rotating handle 6 is rotatably provided at the rear end of the handle 11; a piston assembly 7 is sleeved inside the rotating handle 6 for pressurizing the orientation adjustment assembly 5 to rotate the injection needle 32.

[0049] It should be noted that a T-shaped block 111 is provided inside the handle 11. The T-shaped block 111 is fixedly welded inside the handle 11 and threadedly connected to the rotating handle 6. The piston assembly 7 passes through the T-shaped block 111. When the medical staff rotates the rotating handle 6, the rotating handle 6 will move axially along the T-shaped block 111, thereby pushing the piston assembly 7 to move. Then, the piston assembly 7 pushes the gas inside the handle 11 forward along the pipe 1 into the transmission block 52. Under the action of air pressure, the rear end of the torsion member 53 is squeezed forward along the transmission channel 521. Then, under the action of torque, the torsion member 53 rotates, thereby driving the rotating member to rotate, and then the injection needle 32 rotates accordingly.

[0050] Specific application examples Suspicious mucosal abnormalities (such as erosion, bulging, color changes, etc.) are found during conventional white light or narrow-band imaging (NBI) endoscopy, but the boundaries are unclear. It is necessary to inject tracers (such as methylene blue, indocyanine green) to form a linear marker array around the lesion to clarify the resection range. Alternatively, before ESD / EMR, precise delineation of the lesion edge can significantly reduce the positive margin rate and improve the en bloc resection rate. The determination of the location of this esophageal cancer lesion can be quickly completed by simultaneous injection of multiple needles using an injection device, reducing operation time.

[0051] The specific operating procedure for this device is as follows: The device is inserted through a standard endoscopic working channel (usually 2.8 mm or more) or placed orally as a stand-alone instrument (depending on design compatibility); two tracers are pre-injected into the tracer chamber 31; medical staff slowly insert the tip of the tube 1 into the esophagus through the mouth, directly above the target lesion area; the position of the occlusal component 2 is adjusted to the outside of the patient's lip; the patient bites down on the occlusal balloon 22, rotates the fastening nut 24, pushes it forward along the fastening ring 25, and compresses the supplementary balloon 23; after the supplementary balloon 23 is compressed, the gas enters the occlusal balloon 22 through the through hole of the connecting ring 26, causing it to inflate and fit tightly against the dental arch, achieving oral fixation and sealing, preventing saliva from flowing in, maintaining a clear field of vision, and avoiding device slippage during the operation; Turn on the camera 10 button on the handle 11 to activate the front camera 10 and LED light 9; observe the lesion area in the esophagus through the display, adjust the axial position of the device, and align the multi-needle injection mechanism 3 with the edge of the lesion; If 360° marking around the lesion is required, rotate the handle 6 at the rear end of the handle 11; the handle 6 is pushed along the axis of the T-block 111, pushing the piston assembly 7; the piston compresses the gas inside the handle 11, and the gas enters the transmission channel 521 of the transmission block 52 through the pipe 1; the air pressure pushes the torsion member 53 forward and generates torque, driving the rotating seat 35 (along with the injection needle 32 and the camera 10) to rotate horizontally; so that the injection needle 32 can perform a circular scan with the axis of the pipe 1 as the center, quickly covering the edge of the circumferential lesion; The micro motor in the angle adjustment assembly 33 is activated by the control system (or manual knob, depending on the design); the motor drives the bevel gear set 332, which drives the fixing frame 331 to deflect in the vertical plane (e.g., ±15°~30°); each injection needle 32 adjusts the insertion angle accordingly to adapt to the curvature of the esophageal wall, ensuring that the needle tip is vertical or moderately tilted to pierce the submucosa. Start the gas pump 44 to inject / extract gas into the sealed cavity 411 at the rear of each syringe 41 through the gas tube 43; control the needle depth (usually set to 2–5 mm, penetrating the mucosa muscle layer but not damaging the muscle layer) to avoid perforation; open the corresponding magnetic valve through the control button on the handle 11, start the water pump in the third cavity 313, and push the selected tracer (ICG or methylene blue) through the drug delivery tube 34 to the injection needle 32; inject multiple needles simultaneously or in stages to form discrete or continuous linear markers at the edge of the lesion; after marking, close all valves and retract the injection needle 32; loosen the fastening nut 24, deflate the bite airbag 22, and release the oral fixation; slowly withdraw the device to end the operation.

[0052] In summary, although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the claims and their equivalents.

Claims

1. An injection device for determining the location of esophageal cancer lesions, comprising a tubing (1), with a handle (11) connected to the rear end of the tubing (1), characterized in that, Also includes: The occlusal component (2) is movably fitted onto the tube (1) to adapt to different esophageal lesion locations and is a fixation device; A multi-needle injection mechanism (3) is set at the front end of the tube (1) to form linear marker points at the edge of the esophageal lesion area; A depth control mechanism (4) is located between the multi-needle injection mechanism (3) and the handle (11) to control the injection depth.

2. The injection device for determining the location of esophageal cancer lesions according to claim 1, characterized in that, The occlusal assembly (2) includes: The mouth baffle (21) is movably fitted onto the pipe (1); An occlusal airbag (22) is located in front of the mouth baffle (21); A supplementary airbag (23) is located behind the mouth baffle (21) and is used to inflate the occlusal airbag (22).

3. The injection device for determining the location of esophageal cancer lesions according to claim 2, characterized in that, The multi-needle injection mechanism (3) includes: The tracer chamber (31) is connected to the front end of the pipe (1) and is used to contain the tracer; Multiple injection needles (32) are movably mounted at the front end of the tracer cavity (31) and are all connected to the tracer cavity (31) for injecting tracers at the edge of the esophageal lesion area; An angle adjustment component (33), connected to each injection needle (32), is used to adjust the angle of each injection needle (32) in the vertical direction.

4. The injection device for determining the location of esophageal cancer lesions according to claim 3, characterized in that, The angle adjustment component (33) includes: A mounting bracket (331) is rotatably connected to the front end of the tracer chamber (31) and is used to mount an injection needle (32). A gear set (332) is disposed between the tracer chamber (31) and the fixture (331) for adjusting the angle of the fixture (331).

5. The injection device for determining the location of esophageal cancer lesions according to claim 4, characterized in that, The tracer chamber (31) includes: The first cavity (311) is a ring structure and is connected to the front end of the pipe (1) to contain indocyanine green solution; The second cavity (312) has a U-shaped structure and is connected to the front end of the first cavity (311) to contain the methylene blue solution; The third cavity (313) is located between the first cavity (311) and the second cavity (312), and both the first cavity (311) and the second cavity (312) are connected to the third cavity (313).

6. The injection device for determining the location of esophageal cancer lesions according to claim 5, characterized in that, The injection needle (32) is connected to the third cavity (313) through the drug delivery tube (34).

7. The injection device for determining the location of esophageal cancer lesions according to claim 6, characterized in that, The depth control mechanism (4) includes: Multiple syringes (41) are mounted on a fixture (331) with an open front end for mounting corresponding injection needles (32). Multiple piston plates (42) are slidably and sealed inside the corresponding syringes (41), so that the piston plates (42) and the rear part of the syringes (41) form a sealed cavity (411); each injection needle (32) passes through the corresponding piston plate (42). Multiple air tubes (43) are connected at one end to the corresponding sealed cavity (411) and at the other end to the air pump (44), which are used to draw external gas into the sealed cavity (411) to move the piston plate (42) and control the insertion depth of the injection needle (32).

8. The injection device for determining the location of esophageal cancer lesions according to claim 3, characterized in that, The injection device further includes: The orientation adjustment component (5) is disposed between the tracer chamber (31) and the conduit (1) for adjusting the angle of the injection needle (32) in the horizontal direction.

9. The injection device for determining the location of esophageal cancer lesions according to claim 8, characterized in that, The directional adjustment component (5) includes: The transmission block (52) is coaxially connected to the front end of the pipe (1) at its rear end, and a transmission channel (521) is provided at the center of the transmission block (52). The rear end of the torsion member (53) is slidably and sealed within the transmission channel (521); The front end of the connecting block (54) and the torsion member (53) are connected to the connecting block (54).

10. The injection device for determining the location of esophageal cancer lesions according to claim 9, characterized in that, The handle (11) has a rotating handle (6) at its rear end; a piston assembly (7) is fitted inside the rotating handle (6), and the piston assembly (7) is connected to the directional adjustment assembly (5) through the pipe (1) to pressurize the directional adjustment assembly (5) and make the injection needle (32) rotate.

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