Plant extract-based liposoluble antioxidant and skin lightening compositions and skin care products therefrom

Abstract

The present application relates to a plant extract-based liposoluble antioxidant and skin lightening composition and its skin care product. The plant extract-based liposoluble antioxidant and skin lightening composition comprises the following components by mass fraction: 5-50 of deep sea fish oil, 0.05-2 of tomato fruit extract & jojoba seed oil & squalane compound, and 0.05-1 of jojoba seed extract & olive fruit oil compound. The present application improves the skin lipid content through the synergistic effect of deep sea fish oil, tomato fruit extract & jojoba seed oil & squalane compound, and jojoba seed extract & olive fruit oil compound, resists oxidation in multiple dimensions, removes free radicals, reduces collagen loss, inhibits melanin production, increases skin hyaluronic acid content, enhances the ability of cells to resist oxidation, improves the glossiness and elasticity level of skin cells, and ultimately achieves the effects of antioxidant and overall whitening and skin lightening.

Description

Technical Field

[0001] This invention relates to the field of skincare technology, and in particular to a fat-soluble, antioxidant, and skin-brightening composition based on plant extracts and the skincare product thereof. Background Technology

[0002] As the largest organ in the human body, the skin is constantly exposed to environmental factors such as ultraviolet radiation, air pollution, and blue light radiation, leading to an excessive accumulation of reactive oxygen species (ROS). This triggers oxidative stress, resulting in the excessive production of free radicals and the accumulation of oxidation products. When the number of free radicals exceeds the body's antioxidant capacity, they attack biomolecules such as proteins, lipids, and DNA in skin cells, causing damage to collagen fibers and impairing cell membrane integrity. Ultimately, this manifests as problems such as sagging skin, wrinkles, and dull skin tone.

[0003] Chinese patent CN109260039A discloses a moisturizing and repairing composition and its preparation method. The composition comprises the following components in parts by weight: 20-60 parts squalane, 1-10 parts a complex composed of jojoba seed oil and pomegranate flower extract, 1-5 parts bisabolol, 10-60 parts camellia seed oil, and 5-20 parts Atlantic sea bream oil. The composition organically combines squalane, the complex composed of jojoba seed oil and pomegranate flower extract, bisabolol, camellia seed oil, and Atlantic sea bream oil, exhibiting excellent moisturizing and repairing effects. This approach primarily aims to achieve moisturizing and repairing effects, enhance skin barrier function, reduce moisture evaporation, increase collagen production, and significantly improve dry skin and flaking problems. It does not address much regarding antioxidant properties or skin brightening.

[0004] Chinese patent CN118021638A discloses a glycyrrhizin composition with whitening and freckle-removing effects, comprising ascorbate tetraisopalmitate, isostearyl hydrolyzed collagen, tomato fruit extract, and glycyrrhizin; the weight ratio of ascorbate tetraisopalmitate, isostearyl hydrolyzed collagen, tomato fruit extract, and glycyrrhizin is 0.8-1.2:40-60:4-6:0.1-0.3. This composition, through the combination of different components, achieves excellent whitening and freckle-removing effects. The solution mainly works by reducing melanin production and transfer, brightening skin tone, maintaining skin hydration, effectively reducing skin inflammation and excessive oxidation, and significantly enhancing the whitening and freckle-removing effect. However, the core component of this solution is isostearyl hydrolyzed collagen.

[0005] Chinese patent CN119015179B discloses a compound plant oil and its preparation method, comprising 10%~20% olive fruit oil, 5%-15% jojoba seed oil, 0.1%-1% murehua fruit oil, 0.1%-1% sea buckthorn seed oil, and the balance being sunflower seed oil. However, this method primarily achieves its synergistic effect by regulating skin sebum secretion, repairing the skin barrier, and providing deep nourishment.

[0006] Existing technologies lack compositions or skincare products that can resist oxidation from multiple dimensions, eliminate free radicals, reduce collagen loss, and inhibit melanin production to rejuvenate and brighten the skin. Summary of the Invention

[0007] In order to provide a composition that can resist oxidation in multiple dimensions, eliminate free radicals, reduce collagen loss, inhibit melanin production, and brighten skin tone, the present invention provides a fat-soluble antioxidant and skin-brightening composition based on plant extracts and its skin care products.

[0008] The composition of this invention is a fat-soluble composition with skin antioxidant, skin brightening and skin rejuvenating effects.

[0009] The objective of this invention can be achieved through the following technical solutions: This invention firstly discloses a fat-soluble antioxidant and skin-brightening composition based on plant extracts, comprising the following components in parts by weight: Deep-sea fish oil 5~50, tomato fruit extract & jojoba seed oil & squalane complex 0.05~2, jojoba seed extract & olive fruit oil complex 0.05~1.

[0010] In one embodiment of the present invention, the composition comprises the following components in parts by weight: 10-40 parts deep-sea fish oil, 0.25-1.5 parts tomato fruit extract, jojoba seed oil, and squalane complex, and 0.25-0.5 parts jojoba seed extract and olive fruit oil complex.

[0011] In one embodiment of the present invention, the deep-sea fish oil is selected from Atlantic seabream oil. The composition provided in this application uses deep-sea fish oil (preferably Atlantic seabream oil) as the main component, and is mainly used to improve the structure of the sebaceous layer and enhance the cell membrane's ability to resist oxidation.

[0012] In one embodiment of the present invention, the tomato fruit extract & jojoba seed oil & squalane complex is a complex composed of tomato extract, jojoba seed oil and squalane, wherein the mass ratio of tomato extract, jojoba seed oil and squalane in the complex is 5-10:60-80:10-20, preferably 5-8:70-80:15-20, and more preferably, in 100 parts by mass of the tomato fruit extract & jojoba seed oil & squalane complex, the tomato extract, jojoba seed oil and squalane are 6 parts, 77 parts and 17 parts respectively.

[0013] In one embodiment of the present invention, the preparation method of the tomato fruit extract & jojoba seed oil & squalane complex is as follows: Tomato fruit extract was mixed with squalane for decolorization and extraction. The decolorized and extracted substance is then mixed evenly with jojoba seed oil and filtered to obtain the tomato fruit extract & jojoba seed oil & squalane complex, wherein the mass ratio of tomato extract, jojoba seed oil and squalane is 5-10:60-80:10-20, preferably 5-8:70-80:15-20.

[0014] The tomato fruit extract, also known as tomato fruit extract, is obtained from naturally sourced yellow tomatoes. Its core components are phytohexane and phytooctane, and it is commercially available, for example, as the IBR-TCLC tomato fruit extract from Sage Chemical. The tomato fruit extract can also be prepared using conventional methods in the art.

[0015] The core components of the tomato fruit extract, jojoba seed oil, and squalane complex include hexahydrolycopene and octahydrolycopene from the tomato fruit extract, which have antioxidant, anti-inflammatory, and skin-whitening effects. The tomato fruit extract, jojoba seed oil, and squalane complex can effectively scavenge free radicals, inhibit the production of MMP-1 matrix metalloproteinase, and inhibit melanin production, thus achieving an overall skin-whitening, brightening, and rejuvenating effect.

[0016] In one embodiment of the present invention, the jojoba seed extract & olive fruit oil complex is a complex composed of jojoba seed extract and olive fruit oil, wherein the mass ratio of jojoba seed extract to olive fruit oil in the complex is 1-10:90-99, preferably 1-5:95-99, and more preferably, in 100 parts by mass of the jojoba seed extract & olive fruit oil complex, 4 parts of jojoba seed extract and 96 parts of olive fruit oil are respectively.

[0017] In one embodiment of the present invention, the preparation method of the jojoba seed extract & olive fruit oil complex is as follows: Jojoba seeds are hydrolyzed and filtered to extract the linear fatty alcohols, which are mainly C20-C24, which is the jojoba seed hydrolysate. Olive fruit oil was hydrolyzed by lipase and filtered to obtain 1,2-diglyceride (1,2-DAG); Then, the hydrolyzed jojoba seed extract and the 1,2-diglyceride (1,2-DAG) hydrolyzed from olive fruit oil are mixed evenly to obtain the jojoba seed extract & olive fruit oil complex, wherein the mass ratio of jojoba seed extract to olive fruit oil is 1-10:90-99, preferably 1-5:95-99.

[0018] The jojoba seed extract & olive fruit oil complex primarily consists of 1,2-dAG (1,2-glycerol diglyceride) from olive oil (Olea europaea) and fatty alcohols from jojoba wax (Simmondsia chinensis) (i.e., hydrolyzed products of jojoba wax, mainly C20-C24 straight-chain fatty alcohols). This jojoba seed extract & olive fruit oil complex possesses cell signaling activation properties. It can effectively activate enzyme signals, increase cellular energy, and promote epidermal and dermal regeneration.

[0019] This application utilizes a complex of deep-sea fish oil (preferably Atlantic sea bream oil), tomato fruit extract, jojoba seed oil, and squalane, and a complex of jojoba seed extract and olive fruit oil. The three components work synergistically to revitalize cells, inhibit protein damage, and suppress melanin synthesis, thereby promoting skin whitening and regeneration.

[0020] The present invention further provides a fat-soluble skin care product based on plant extracts that has antioxidant and skin-brightening properties, comprising the following components in the indicated mass percentages: 5-50% deep-sea fish oil, 0.05-2% tomato fruit extract, jojoba seed oil, and squalane complex, 0.05-1% jojoba seed extract and olive fruit oil complex, with the remainder being skin care excipients.

[0021] Preferably, the product contains the following components in the indicated mass percentages: 10-40% deep-sea fish oil (preferably Atlantic sea bream oil), 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, with the remainder being excipients for skincare products.

[0022] In one embodiment of the present invention, the skin care product is an essential oil, essence, serum, lotion, or cream.

[0023] In one embodiment of the present invention, the skin care product is an essential oil, which comprises the following components in the indicated mass percentages: 10-40% Atlantic sea bream oil, 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, 0.01%-0.1% colorant, 0.01%-0.2% fragrance, and the balance being other base oils.

[0024] Preferably, the colorant includes oil-soluble pigments such as CI 47000 oil-soluble yellow, CI 61565 oil-soluble green, and CI 60725 oil-soluble purple, as well as one or more natural plant pigments that can be specifically used for color adjustment, such as carotene oil, Brich fruit oil, and some fermented plant pigments.

[0025] Preferably, the fragrance includes one or more of the following: various cosmetic fragrances, (daily) fragrances, edible fragrances, and various aromatic essential oils.

[0026] Preferably, other base oils include, but are not limited to, one or more of isopropyl palmitate, isopropyl myristate, isononyl isononanoate, cetyl ethylhexanoate, ethylhexyl palmitate, caprylic / capric triglyceride, hydrogenated polydecene, octyl dodecyl alcohol, C13-16 isoparaffins, isohexadecane, isodecane, C9-12 alkyl, mineral oil, and European hazelnut oil.

[0027] The present invention further provides a method for preparing a fat-soluble, antioxidant, and skin-brightening skincare product based on plant extracts. The method is as follows: deep-sea fish oil (preferably Atlantic sea bream oil) and other base oils are added to a reactor in sequence and stirred at 10-30 rpm for 10-30 minutes until the material is completely and evenly dispersed. Then, tomato fruit extract, jojoba seed oil and squalane complex, jojoba seed extract and olive fruit oil complex, as well as colorant and fragrance are added in sequence and stirred at 10-30 rpm for 10-30 minutes until the material is completely and evenly dispersed. The mixture is then filtered through a 200-1000 mesh filter cloth to obtain the fat-soluble, antioxidant, and skin-brightening skincare product based on plant extracts.

[0028] In one embodiment of the invention, it is ensured that there is no residual moisture in the reactor before preparation.

[0029] The present invention further provides a method for non-therapeutic antioxidant skin rejuvenation by applying the composition or the skin care product to facial skin.

[0030] This application uses deep-sea fish oil (Atlantic tilapia oil) as the main ingredient. Atlantic tilapia oil is a natural oil refined from highly refined Atlantic tilapia oil. Through advanced deoxygenation, decolorization, and selective hydrogenation, its oxidative stability is enhanced while retaining most of its active nutrients. It possesses a pleasant texture not found in other natural oils. Its composition is rich in DHA, EPA, omega-3, and other polyunsaturated fatty acids, which can help the skin form a "moisture-locking protective layer" and reduce moisture loss. It can replenish the wax esters and free fatty acids in the skin's sebum, improve the structure of the sebum layer, and enhance the cell membrane's ability to resist oxidation.

[0031] In this application, the tomato fruit extract, jojoba seed oil, and squalane complex possesses multiple functions, including antioxidant, anti-inflammatory, free radical scavenging, matrix metalloproteinase inhibition, and melanin inhibition. Its mechanism of action primarily involves the absorption of harmful ultraviolet radiation from sunlight through phytohexane and phytooctane, thus combating photoaging. In vitro experimental data show that this complex effectively captures and scavenges DPPH free radicals. In vitro cell experiments demonstrate that this complex inhibits the secretion of PGE-2 (interleukin-2) by fibroblasts upon stimulation, proving its anti-inflammatory effects. Similarly, in vitro cell experiments show that this complex inhibits the release of MMP-1 (matrix metalloproteinase) by fibroblasts during inflammatory responses, thereby reducing intracellular collagen loss, indicating that the complex has certain anti-aging effects. In vitro experiments, co-culturing human keratinocytes and melanocytes and inducing them with α-MSH, revealed that this complex can increase the expression of the ZGP1 (zinc-binding α2-glycoprotein) gene, thereby inhibiting melanin production through ZGP1 and resulting in a more even skin tone.

[0032] In this application, the jojoba seed extract & olive fruit oil complex mainly comprises 1,2-DAG and hydrolysate of jojoba wax extracted from jojoba seeds (high molecular weight linear fatty alcohols, primarily C20-24). This complex enhances the efficiency of intracellular signal transduction and promotes the regeneration of the epidermis and dermis. As a signaling factor, this complex stimulates G protein-coupled receptors and tyrosine kinase receptors on the cell membrane. The mechanism of action of this signaling factor is through promoting the expression of PKCδ protein kinase, enhancing the effect of positive signal transduction; regulating MAP kinases (ERK1 / ERK2), thus playing an important role in transmembrane signal transduction essential for cell growth and differentiation; and sequentially increasing Ca... 2+Calcium signals activate various calcium-dependent enzymes, enhancing cell function and epidermal differentiation expression; they also increase ATP synthesis and cell ATP content, thereby improving signal transduction efficiency; through the above pathways, they ultimately increase the expression levels of keratin, epidermal proteins, filaggrin, integrin β1, fibronectin, collagen I, and collagen III, and enhance hyaluronic acid expression in the skin, ultimately achieving overall anti-aging and skin-revitalizing effects.

[0033] This application utilizes Atlantic sea bream oil to replenish the skin with various unsaturated fatty acids, enhancing the skin's antioxidant capacity and repairing the lipid barrier to achieve skin rejuvenation. Simultaneously, tomato fruit extract, as a naturally extracted carotenoid, exhibits significant effects in combating photoaging, scavenging free radicals, protecting against collagen loss, and inhibiting melanin production. By combining tomato fruit extract with squalane from jojoba seed oil, a stronger overall skin-brightening effect is achieved. The jojoba seed extract & olive fruit oil complex, by influencing cell signaling levels, promotes cell metabolism, activates cells, and promotes the expression of various proteins. Ultimately, this achieves the effect of resisting skin oxidation and revitalizing the skin.

[0034] This application utilizes the synergistic effects of Atlantic sea bream oil, a tomato fruit extract complex (tomato fruit extract, jojoba seed oil, and squalane complex), and cell signaling factors (jojoba seed extract and olive fruit oil complex) to increase skin lipid content, provide multi-dimensional antioxidant protection, eliminate free radicals, reduce collagen loss, inhibit melanin production, and increase skin hyaluronic acid content. This enhances the cells' ability to resist oxidation, improves skin cell radiance and elasticity, and achieves both antioxidant and overall whitening and skin rejuvenation effects. The multi-pathway approach of antioxidant, repair, and skin rejuvenation and whitening results in a "stable inside and radiant outside" skin condition.

[0035] This invention investigates and analyzes the application efficacy of tomato fruit extract oil-soluble lipid complexes in cosmetics.

[0036] This invention has discovered the anti-aging and fine line repair effects of deep-sea fish oil (Atlantic sea bream oil), and further combined it with other ingredients to improve its effects in anti-aging and overall skin brightening.

[0037] This invention studies and verifies the use of jojoba seed extract as an anti-aging and skin-revitalizing ingredient in skincare products, demonstrating its significant effects in enhancing skin elasticity and improving facial skin radiance.

[0038] Compared with the prior art, the present invention has the following beneficial effects: 1. Atlantic sea bream oil has a pleasant texture that other natural oils do not have. Its ingredients are rich in DHA, EPA, omega-3 and other unsaturated fatty acids, which can help the skin form a "moisture-locking protective layer" and reduce moisture loss. By adding Atlantic sea bream oil, the wax ester and free fatty acid components in the skin's sebum can be replenished, the structure of the sebum layer can be improved and the cell membrane's ability to resist oxidation can be enhanced.

[0039] 2. The tomato fruit extract, jojoba seed oil, and squalane complex can effectively scavenge free radicals, inhibit the production of MMP-1 matrix metalloproteinases, and suppress melanin production. By adding the tomato fruit extract, jojoba seed oil, and squalane complex, it can resist photoaging, eliminate free radicals, protect against collagen loss, and inhibit melanin production. When combined with other ingredients, it can achieve stronger antioxidant, anti-inflammatory, and skin-whitening effects.

[0040] 3. Jojoba seed extract & olive fruit oil complex promotes cell metabolism, activates cells, and promotes the expression of various proteins by affecting the level of cell signaling; adding jojoba seed extract & olive fruit oil complex can effectively reduce the appearance of aging skin.

[0041] 4. By adding Atlantic sea bream oil, a complex of tomato fruit extract, jojoba seed oil and squalane, and a complex of jojoba seed extract and olive fruit oil, the three complement each other from different cellular dimensions, working from the inside out to deeply resist sebum oxidation and cell oxidation, enhance cell elasticity, improve skin elasticity and firmness, and achieve antioxidant and overall whitening and skin rejuvenation effects.

[0042] 5. Antioxidant, repair, and skin-renewing whitening work together to improve skin condition, resulting in "internal stability and external radiance". Attached Figure Description

[0043] Figure 1 These are case studies of improved facial radiance in some subjects of this invention. Detailed Implementation

[0044] This invention first discloses a fat-soluble antioxidant and skin-brightening composition based on plant extracts, comprising the following components in parts by weight: 5-50 parts deep-sea fish oil, 0.05-2 parts tomato fruit extract, jojoba seed oil, and squalane complex, and 0.05-1 parts jojoba seed extract and olive fruit oil complex. Preferably, the composition comprises the following components in parts by weight: 10-40 parts deep-sea fish oil, 0.25-1.5 parts tomato fruit extract, jojoba seed oil, and squalane complex, and 0.25-0.5 parts jojoba seed extract and olive fruit oil complex.

[0045] In one embodiment of the present invention, the deep-sea fish oil is selected from Atlantic seabream oil. The composition provided in this application uses Atlantic seabream oil as the main component and is mainly used to improve the structure of the sebaceous layer and enhance the cell membrane's ability to resist oxidation.

[0046] In one embodiment of the present invention, the tomato fruit extract & jojoba seed oil & squalane complex is a complex composed of tomato extract, jojoba seed oil and squalane, wherein the mass ratio of tomato extract, jojoba seed oil and squalane in the complex is 5-10:60-80:10-20, preferably 5-8:70-80:15-20.

[0047] The core components of the tomato fruit extract, jojoba seed oil, and squalane complex include hexahydrolycopene and octahydrolycopene from the tomato fruit extract, which have antioxidant, anti-inflammatory, and skin-whitening effects. The tomato fruit extract, jojoba seed oil, and squalane complex can effectively scavenge free radicals, inhibit the production of MMP-1 matrix metalloproteinase, and inhibit melanin production, thus achieving an overall skin-whitening, brightening, and rejuvenating effect.

[0048] In one embodiment of the present invention, the jojoba seed extract & olive fruit oil complex is a complex composed of jojoba seed extract and olive fruit oil, wherein the mass ratio of jojoba seed extract to olive fruit oil in the complex is 1-10:90-99, preferably 1-5:95-99.

[0049] The jojoba seed extract & olive fruit oil complex primarily comprises 1,2-dAG (1,2-glycerol diglyceride) from olive oil (Olea europaea) and fatty alcohols from jojoba wax (Simmondsia chinensis). This complex exhibits cell signaling activation properties. It effectively activates enzyme signals, increases cellular energy, and promotes epidermal and dermal regeneration.

[0050] This invention further provides a fat-soluble, antioxidant, and skin-brightening skincare product based on plant extracts, comprising the following components in the indicated weight percentages: 5-50% deep-sea fish oil, 0.05-2% tomato fruit extract, jojoba seed oil, and squalane complex, 0.05-1% jojoba seed extract and olive fruit oil complex, with the remainder being skincare excipients. Preferably, it comprises the following components in the indicated weight percentages: 10-40% deep-sea fish oil (preferably Atlantic snapper oil), 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, with the remainder being skincare excipients.

[0051] In one embodiment of the present invention, the skin care product is an essential oil, essence, serum, lotion, or cream.

[0052] In one embodiment of the present invention, the skincare product is an essential oil, which comprises the following components in the indicated mass percentages: 5-50% deep-sea fish oil, 0.05-2% tomato fruit extract, jojoba seed oil, and squalane complex, 0.05-1% jojoba seed extract and olive fruit oil complex, 0.01%-0.1% colorant, 0.01%-0.2% fragrance, and the balance being other base oils. Preferably, the essential oil comprises the following components in the indicated mass percentages: 10-40% Atlantic sea bream oil, 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, 0.01%-0.1% colorant, 0.01%-0.2% fragrance, and the balance being other base oils.

[0053] Preferably, the colorant includes oil-soluble pigments such as CI 47000 oil-soluble yellow, CI 61565 oil-soluble green, and CI 60725 oil-soluble purple, as well as one or more natural plant pigments that can be specifically used for color adjustment, such as carotene oil, Brich fruit oil, and some fermented plant pigments.

[0054] Preferably, the fragrance includes one or more of the following: various cosmetic fragrances, (daily) fragrances, edible fragrances, and various aromatic essential oils.

[0055] Preferably, other base oils include, but are not limited to, one or more of isopropyl palmitate, isopropyl myristate, isononyl isononanoate, cetyl ethylhexanoate, ethylhexyl palmitate, caprylic / capric triglyceride, hydrogenated polydecene, octyl dodecyl alcohol, C13-16 isoparaffins, isohexadecane, isodecane, C9-12 alkyl, mineral oil, and European hazelnut oil.

[0056] The following embodiments of this application: Atlantic seabream oil can be obtained through commercial channels.

[0057] The preparation method of the tomato fruit extract, jojoba seed oil, and squalane complex is as follows: Tomato fruit extract was mixed with squalane for decolorization and extraction. The decolorized and extracted substance was then thoroughly mixed with jojoba seed oil and filtered to obtain the tomato fruit extract, jojoba seed oil, and squalane complex, wherein the mass ratio of tomato extract, jojoba seed oil, and squalane was 6:77:17. The tomato fruit extract, also known as tomato fruit extract, is extracted from naturally sourced yellow tomatoes. Its core components are phytohexane and phytooctahydroxane, and it is commercially available, for example, as the IBR-TCLC tomato fruit extract from Sage Chemical.

[0058] The preparation method of the jojoba seed extract & olive fruit oil complex is as follows: The hydrolyzed jojoba seeds are filtered and the C20-C24 main linear fatty alcohols are extracted to obtain the jojoba seed hydrolysate. Olive fruit oil was hydrolyzed by lipase and filtered to obtain 1,2-diglyceride (1,2-DAG); The jojoba seed hydrolysate and the 1,2-diglyceride (1,2-DAG) hydrolyzed from olive fruit oil are then mixed evenly in a specific ratio to obtain the jojoba seed extract & olive fruit oil complex, wherein the mass ratio of jojoba seed extract to olive fruit oil is 4:96.

[0059] The present invention will now be described in detail with reference to the accompanying drawings and specific embodiments. These embodiments are based on the technical solution of the present invention and provide detailed implementation methods and specific operating procedures. However, the scope of protection of the present invention is not limited to the following embodiments.

[0060] Example 1 Provide an essential oil and its preparation method Table 1. Proportion of each component in the formula of essential oils

[0061] The essential oil is prepared by the following method: S1: After cleaning the main pot, dry it until there is no moisture left inside, and set it aside.

[0062] S2: Add the corresponding amount of Western sea bream oil and other base oils from Table 1 into the mixing bowl in sequence. Turn on the mixing bowl and stir at 10-30 rpm for 10-30 minutes until the ingredients in the bowl are completely dispersed and evenly distributed to obtain the base oil portion.

[0063] S3: After thoroughly mixing the base oils, add the corresponding amounts of tomato fruit extract, jojoba seed oil, and squalane complex, jojoba seed extract and olive fruit oil complex, as well as pigments and flavorings, as listed in Table 1. Turn on the mixing bowl and stir at 10-30 rpm for 10-30 minutes until the mixture is completely homogeneous. Filter the mixture through a 200-1000 mesh filter cloth to obtain the desired essential oil.

[0064] Based on the above preparation method, specific Examples 1-6 and Comparative Examples 1-7 are provided.

[0065] The difference between Comparative Example 1 and Example 1 is that Comparative Example 1 is only missing the complex of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane and the complex of jojoba seed extract & olive fruit oil, and serves as a blank comparative example. The difference between Comparative Examples 2-4 and Example 1 is that they lack only one component from the composition of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex, thus verifying the effectiveness of a single ingredient in the composition. The only difference between Comparative Examples 5-7 and Example 1 is the absence of two components from the compositions of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex, to verify the efficacy enhancement compared to a single component.

[0066] Examples 2-6 differ from Example 1 only in the increased content of one or three components in the compositions of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex. This was used to verify that the three combinations exhibited superior efficacy compared to single components or combinations of any two components. Furthermore, comparative analysis of different formulation ratios verified the differences in efficacy expression of the compositions under different efficacy ratios. This also validated their efficacy in skin anti-oxidation and skin rejuvenation.

[0067] For specific proportions, please refer to Table 2: Table 2: Component Proportions of Comparative Examples and Embodiments

[0068] Characterization data and effect data of the products in the examples and comparative examples The Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex in different proportions were combined in the examples in Table 2 and applied to essential oil products. The efficacy of this lipid-soluble composition in skin anti-oxidation and skin whitening was tested by comparing and analyzing the experimental data with those of comparative examples.

[0069] Characterization data and effect data of the products in the examples and comparative examples: 1. Security Testing 1) Test samples: the essential oils of Comparative Examples 1-7 and Examples 1-6 as described in Table 1.

[0070] 2) Number of participants: 39, half male and half female, aged between 18 and 50 years old, all of whom met the criteria for participants.

[0071] 3) Testing Method: 39 participants meeting the subject criteria were randomly divided into 13 groups, corresponding to the essential oils of Comparative Examples 1-7, Examples 1-6, and a blank group (no sample applied). Each group consisted of 3 participants. Safety was tested by a third-party testing agency. Areas not exceeding 50 mm² were selected. 2 A suitable patch applicator with a depth of approximately 1 mm was used. Approximately 0.02-0.025 ml (g) of the test substance was added to the patch test container using a closed patch test method. The patch test container was applied to the flexor side of the subject's forearm. After 24 hours, the test substance was removed, and skin reactions were observed at 0.5 h, 24 h, and 48 h after removal. The results were recorded according to the skin reaction grading standards in the "Cosmetic Safety Technical Regulations 2015".

[0072] Table 3: Results of Patch Experiment

[0073] Note: Skin reaction grading standards: Grade 0: Negative reaction; Grade 1: Suspicious reaction; only slight erythema; Grade 2: Weak positive reaction (erythema reaction); erythema, infiltration, edema, and papules may be present; Grade 3: Strong positive reaction (herpes reaction); erythema, infiltration, edema, papules, herpes: the reaction may extend beyond the tested area; Grade 4: Extremely strong reaction (confluent herpes simplex reaction): obvious erythema, severe infiltration, edema, confluent herpes simplex, reaction extending beyond the test area.

[0074] Test results: Table 3 shows no irritation, indicating a safe pass.

[0075] 2. Efficacy Evaluation Test (1) In vitro antioxidant test experiment The DPPH method was used to determine the free radical scavenging ability of the samples. Experimental groups 1-12 were the essential oils prepared in Examples 1-6 and Comparative Examples 2-7, respectively, while the blank control group was the essential oil shown in Comparative Example 1 without any of the components in the composition of this invention.

[0076] Prepare a 1 g / L skin care oil sample solution using anhydrous ethanol. Add 2 ml of the sample solution and 2 ml of 0.1 mmol / L DPPH solution to a 1 cm quartz cuvette, mix well, and let stand in the dark for 30 min. Use 95% ethanol solution as a reference solution to measure the absorbance A of the sample at 517 nm. Similarly, measure the absorbance A0 of the sample after mixing 2 ml of the sample solution and 2 ml of 95% ethanol solution and standing in the dark at 517 nm, and the absorbance A1 of the sample after mixing 2 ml of DPPH solution and 2 ml of 95% ethanol solution and standing in the dark at 517 nm, according to the formula: Free radical scavenging rate of the composition (%) = [1 - (absorbance A of skin care oil sample with added DPPH - absorbance A0 of reference solution) / absorbance A1 of DPPH ethanol solution] × 100% Calculate the scavenging rate of DPPH free radicals.

[0077] Table 4: Free radical scavenging rates of each comparative example and embodiment

[0078] Analysis of the data in Table 4 shows that: Comparing the data of experimental groups 7-9 with the blank control group, it was found that the DPPH scavenging rate of the experimental groups that were individually supplemented with any one of the three components—Atlantic scabbard sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex—was higher than that of the blank group, proving that all three components have antioxidant effects. Comparing the data from experimental group 7 + experimental group 8 with the data from experimental group 10; comparing the data from experimental group 7 + experimental group 9 with the data from experimental group 11; and comparing the data from experimental group 8 + experimental group 9 with the data from experimental group 12, the DPPH scavenging rate showed a 1+1>2 effect, proving that different antioxidant components have a synergistic effect.

[0079] Compared with experimental groups 7-9 and 10-12, experimental group 1 (Example 1) showed that its DPPH scavenging rate was the strongest under the synergistic condition of the three, showing the effect of 1+1+1>2+1. The synergistic effect of the three greatly improved the antioxidant capacity of each component in the whole product system.

[0080] The comparisons between experimental groups 1 and 2, 1 and 3, and 4 demonstrate that the antioxidant effects of the three components—Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex—are positively correlated with the amount of each component added.

[0081] Comparative analysis of experimental groups 5 and 6 showed that the synergistic effect of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex significantly improved the overall antioxidant efficacy of the product after increasing the amount of each component. However, after reaching a certain amount, the antioxidant level was already high, and the doubling of the component amount no longer significantly improved the antioxidant efficacy, showing a certain marginal effect.

[0082] (2) Human efficacy testing experiment In vitro antioxidant assays showed that the compositions of Atlantic sea bream oil, tomato fruit extract, jojoba seed oil, and squalane complex, and jojoba seed extract and olive fruit oil complex, exhibit synergistic antioxidant effects. Therefore, the above comparative examples and embodiments were used as experimental samples to further analyze and verify the effectiveness of these compositions in brightening facial skin, improving facial radiance, and enhancing facial skin tone.

[0083] 1) Skin luster and skin tone test experiment The effects of the comparative examples and embodiments of the synergistic effect experiment of the antioxidant skin-renewing composition were verified (skin renewal evaluation - brightening, whitening). The experimental steps and results are as follows: Test subjects: 39 healthy women (aged 25-45) were divided into 13 groups of 3 people each, and each group used the same formula product.

[0084] Test area: face (left face blank control sample, right face comparative sample or example sample); Usage: Use twice daily, morning and evening, for 4 weeks. Testing instrument: Delfin SkinColorCatch (Finland) Performance indicators: The changes in color brightness (ΔL*) and ITA° are measured. In this invention, L* value (brightness) and ITA° (skin color individual type angle) are mainly used as indicators.

[0085] Calculation formula: (1): ΔL * = [L * (1 month after testing the product of the comparative example) - L * (before the start of the test)] - [L * (1 month after testing the blank product) - L * (before the start of the test)] (2): ITA° (represents the overall change in chroma; the higher the ITA° value, the lighter the skin tone). As shown in Table 5: Table 5: ITA° range and skin color classification

[0086] =The average value of each group before the start of the experiment; =The average value of each group after the product has been tested for 1 month.

[0087] The test results are shown in Table 6 below: Table 6: Skin brightness and skin color change test results of each comparative example and embodiment in Table 1

[0088]

[0089] Analysis of the data in Table 6 shows that: The antioxidant skin-renewing composition of this invention has a significant effect on improving facial radiance and skin tone through the synergistic effect between its components. Moreover, comparing the change rate data of D7 and D28, the skin brightening effect on day 28 is more obvious than the effect of 7 days of use as the usage time increases.

[0090] By comparing Examples 1-6 with Comparative Examples 2-4 and Comparative Examples 5-7, it can be concluded that the synergistic effect of the three components is significantly more pronounced than that of a single component or a combination of two components. Furthermore, the brightening and skin-tone-improving effects are positively correlated with the amount of the active ingredient added. This verifies that the composition of this invention possesses skin-rejuvenating effects in enhancing skin brightness and improving skin tone.

[0091] The human efficacy data from Example 1 reflects that, compared to before use, after 28 days of using the test sample, the facial skin color L* value increased by 4.2, an improvement rate of 16.93%, which is a significant improvement. Figure 1 The images shown are specific examples of improved facial radiance in some subjects.

[0092] 2) Skin texture area test The effects of the comparative examples and embodiments of the synergistic effect experiment of the anti-oxidative skin-renewing composition were verified (skin renewal evaluation - anti-aging and firming). The experimental steps and results are as follows: Test subjects: 39 healthy women (aged 25-45) were divided into 13 groups of 3 people each, and each group used the same formula product.

[0093] Test area: face (left face blank control sample, right face comparative sample or example sample); Usage: Use twice daily, morning and evening, for 4 weeks. Test instrument: VECTRA H1 3D imaging simulation system Effect Indicator: By taking two or more digital images of the same object from different positions and directions, and then processing, matching, analyzing, and calculating the images, the precise three-dimensional coordinates of the skin surface are obtained. The measurement principle is triangulation. Photogrammetry determines the position, size, and shape of the object being measured by analyzing images recorded on film or electronic media. The indicator for this round of testing is the facial texture area; a decreasing trend in its value indicates greater improvement.

[0094] The test results are shown in Table 7 below: Table 7: Change rate of facial skin texture area in each comparative example and embodiment of Table 1

[0095] Note: Rate of change = (Measurement after use - Measurement before use) / Measurement before use * 100%.

[0096] Analysis of the data in Table 7 shows that: The antioxidant skin-renewing composition of the present invention has a significant effect on reducing fine lines on the face through the synergistic effect between its components.

[0097] By comparing Comparative Examples 2-4 with the blank control Comparative Example 1, Atlantic scorpionfish oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex all showed some effect in reducing facial fine lines. The tomato fruit extract & jojoba seed oil & squalane complex was slightly more effective than the jojoba seed extract & olive fruit oil complex in reducing fine lines. The tomato fruit extract & jojoba seed oil & squalane complex and the jojoba seed extract & olive fruit oil complex were both quite effective and significantly stronger than Atlantic scorpionfish oil.

[0098] By comparing Examples 1-6 with Comparative Examples 2-4 and Comparative Examples 5-7, it can be concluded that the synergistic effect of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex is significantly more pronounced than that of any single component or any combination of two components.

[0099] The human efficacy data from Example 1 reflect that, compared to before use, after 28 days of using the test sample, the average area of ​​fine lines on the test subjects' faces decreased from 3.40 mm. Reduced to 2.64 The overall area of ​​fine lines decreased by 22.35%, indicating a significant improvement in the smoothness of the test subjects' faces. This demonstrates that the combination of Atlantic sea bream oil, tomato fruit extract & jojoba seed oil & squalane complex, and jojoba seed extract & olive fruit oil complex has a significant effect on improving facial skin smoothness.

[0100] In summary, the in vitro antioxidant test, human efficacy test 1), and human efficacy test 2) show that the composition described in this invention has significant effects on skin antioxidant, skin brightness enhancement, facial skin tone improvement, and facial skin smoothness improvement, demonstrating the overall antioxidant and skin rejuvenation effects of the composition.

[0101] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Therefore, any simple modifications, equivalent changes, and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A fat-soluble, antioxidant, and skin-brightening composition based on plant extracts, characterized in that, It includes the following components in parts by weight: 5-50 parts deep-sea fish oil, 0.05-2 parts tomato fruit extract, jojoba seed oil and squalane complex, and 0.05-1 parts jojoba seed extract and olive fruit oil complex.

2. The composition based on plant extracts that is a fat-soluble antioxidant and skin-brightening agent according to claim 1, characterized in that, It includes the following components in parts by weight: 10-40 parts deep-sea fish oil; 0.25-1.5 parts tomato fruit extract, jojoba seed oil, and squalane complex; and 0.25-0.5 parts jojoba seed extract and olive fruit oil complex.

3. The composition based on plant extracts, a fat-soluble antioxidant and skin-brightening composition according to claim 1, characterized in that, The deep-sea fish oil mentioned is Atlantic sea bream oil.

4. The composition based on plant extracts that is a fat-soluble antioxidant and skin-brightening agent according to claim 1, characterized in that, The tomato fruit extract, jojoba seed oil, and squalane complex is a complex composed of tomato extract, jojoba seed oil, and squalane. The mass ratio of tomato extract, jojoba seed oil, and squalane in the complex is 5-10:60-80:10-20, preferably 5-8:70-80:15-20.

5. The composition based on plant extracts, a fat-soluble antioxidant and skin-brightening composition according to claim 1, characterized in that, The preparation method of the tomato fruit extract, jojoba seed oil, and squalane complex is as follows: Mix tomato fruit extract with squalane; After the decolorized and extracted substance is mixed evenly with jojoba seed oil, the tomato fruit extract, jojoba seed oil and squalane complex is obtained, wherein the mass ratio of tomato extract, jojoba seed oil and squalane is 5-10:60-80:10-20, preferably 5-8:70-80:15-20.

6. The composition based on plant extracts, a fat-soluble antioxidant and skin-brightening composition according to claim 1, characterized in that, The jojoba seed extract & olive fruit oil complex is a complex composed of jojoba seed extract and olive fruit oil, wherein the mass ratio of jojoba seed extract to olive fruit oil in the complex is 1-10:90-99, preferably 1-5:95-99.

7. The composition based on plant extracts, a fat-soluble antioxidant and skin-brightening composition according to claim 1, characterized in that, The preparation method of the jojoba seed extract & olive fruit oil complex is as follows: Jojoba seeds are hydrolyzed and filtered to extract the linear fatty alcohols, which are mainly C20-C24, which is the jojoba seed hydrolysate. 1,2-diglyceride was obtained by hydrolyzing olive fruit oil with lipase and filtering. The jojoba seed hydrolysate is then mixed evenly with the 1,2-glycerol diester of the olive fruit oil hydrolysate to obtain the jojoba seed extract & olive fruit oil complex, wherein the mass ratio of jojoba seed extract to olive fruit oil is 1-10:90-99, preferably 1-5:95-99.

8. A fat-soluble skincare product based on plant extracts that provides antioxidant and skin-brightening effects, characterized in that... It contains the following components in the indicated weight percentages: deep-sea fish oil 5-50%, tomato fruit extract, jojoba seed oil, and squalane complex 0.05-2%, jojoba seed extract and olive fruit oil complex 0.05-1%, and the remainder are excipients for skincare products. Preferably, the product contains the following components in the indicated mass percentages: 10-40% deep-sea fish oil, 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, with the remainder being excipients for skincare products. The skincare products mentioned are essential oils, serums, lotions, emulsions, and creams.

9. A skincare product based on plant extracts that is fat-soluble, antioxidant, and brightens skin tone, as described in claim 8, characterized in that... The skincare product is an essential oil, which comprises the following components in the indicated mass percentages: 10-40% Atlantic sea bream oil, 0.25-1.5% tomato fruit extract, jojoba seed oil, and squalane complex, 0.25-0.5% jojoba seed extract and olive fruit oil complex, 0.01%-0.1% colorant, 0.01%-0.2% fragrance, and the remainder being other base oils.

10. A skincare product based on plant extracts that is fat-soluble, antioxidant, and brightens skin tone, as described in claim 9, characterized in that... The colorant is selected from one or more of CI 47000 oil-soluble yellow, CI 61565 oil-soluble green, CI 60725 oil-soluble purple, carotene oil, and Brich fruit oil. Other base oils are selected from one or more of the following: isopropyl palmitate, isopropyl myristate, isononyl isononanoate, cetyl ethylhexanoate, ethylhexyl palmitate, caprylic / capric triglyceride, hydrogenated polydecene, octyl dodecyl alcohol, C13-16 isoparaffins, isohexadecane, isododecane, C9-12 alkyl, mineral oil, and European hazelnut oil.

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