Testis tablet for promoting male growth and development and its preparation method
By modifying the mesoporous magnesium aluminum silicate complex and the phosphoric acid-functionalized calcium phosphate-titanium dioxide nanocomposite excipients, the problem of difficult tablet preparation caused by the high oil content of testicular tablets was solved, achieving high drug loading and improved stability, and significantly improving the clinical efficacy and storage stability of testicular tablets.
CN122140645APending Publication Date: 2026-06-05JIANGXI ZEZHONG PHARM CO LTD
Patent Information
- Authority / Receiving Office
- CN Β· China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- JIANGXI ZEZHONG PHARM CO LTD
- Filing Date
- 2026-03-12
- Publication Date
- 2026-06-05
Abstract
The application discloses a kind of testis tablets for promoting male growth and development and preparation method thereof in the technical field of pharmaceutical preparation, first, modified mesoporous magnesium aluminum silicate complex and phosphoric acid functionalized calcium phosphate-titanium dioxide nanocomposite are prepared respectively, the former is synthesized by template agent oriented hydrothermal reaction under specific weak alkaline condition, and the latter is synthesized by coprecipitation and reflux aging reaction regulated by citrate.The dry powder of bovine testis is mixed with the above two kinds of adjuvant and microcrystalline cellulose, croscarmellose sodium and the like, and the testis tablets are prepared by granulation, adding magnesium stearate lubricant and then pressing and coating.The key innovation of the application lies in the efficient adsorption of two new adjuvants to adsorb the oil in bovine testis, and the content of dry powder of bovine testis in each testis tablet is 0.38g, thereby significantly improving the bioavailability and clinical efficacy of the preparation, and the product quality is stable and suitable for industrial production.
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