A hot pack for treating postoperative paralytic ileus of abdominal tumor and a preparation method thereof
By using a hot compress to administer medication, the combination of traditional Chinese medicine and a heat-conducting medium directly relieves paralytic ileus after abdominal tumor surgery. This method solves the problems of poor drug absorption and side effects in existing technologies, achieving a rapid and non-invasive therapeutic effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CANCER CENT OF GUANGZHOU MEDICAL UNIV
- Filing Date
- 2026-04-29
- Publication Date
- 2026-06-05
AI Technical Summary
In treating paralytic ileus after abdominal tumor surgery, existing technologies have limited effectiveness in treating paralytic ileus, with oral medications being difficult to absorb and utilize, and also presenting side effects. Existing traditional Chinese medicine treatments are also limited in their effectiveness in treating gastrointestinal paralysis and cannot effectively relieve symptoms.
The drug is administered via external application of a hot compress containing a traditional Chinese medicine composition (Perilla frutescens seed, Magnolia officinalis, Citrus aurantium, Evodia rutaecarpa, Aucklandia lappa, and Raphanus sativus seed) and a heat-conducting medium (coarse salt). It is heated in a microwave oven and applied to the periumbilical region and related acupoints on the abdomen, acting directly on the gastrointestinal tract and promoting transdermal absorption of the drug.
It quickly relieves intestinal obstruction symptoms, avoids the side effects of oral medications, improves patient compliance, and is easy to use, making it suitable for widespread application in medical institutions and homes.
Abstract
Description
Technical Field
[0001] This invention relates to the field of traditional Chinese medicine technology, specifically to a hot compress for treating paralytic ileus after abdominal tumor surgery and its preparation method. Background Technology
[0002] Paralytic ileus is a common complication after abdominal tumor surgery, mainly manifested as abdominal distension, abdominal pain, cessation of flatus and defecation, and decreased or absent bowel sounds. The pathogenesis of this condition is complex, related to multiple factors including surgical trauma, anesthetic drug use, inflammatory response, inhibition of nerve reflexes, and electrolyte imbalance. Postoperative paralytic ileus not only exacerbates patient suffering, prolongs hospital stay, and increases medical costs, but may also lead to intestinal adhesions, intestinal perforation, and electrolyte imbalances, affecting postoperative recovery and the implementation of subsequent anti-tumor treatment.
[0003] Currently, modern medicine treats postoperative paralytic ileus primarily through a combination of measures, including fasting, gastrointestinal decompression, maintaining electrolyte balance, and the use of prokinetic drugs (such as metoclopramide and mosapride) and peripheral opioid receptor antagonists (such as avimopan). However, fasting, gastrointestinal decompression, and maintaining electrolyte balance have limited effects on regulating postoperative gastrointestinal dysfunction, and the use of drugs or antagonists can cause cardiovascular side effects.
[0004] Traditional Chinese medicine (TCM) considers postoperative abdominal intestinal paralysis to fall under the categories of "intestinal obstruction" and "blockage." Surgical trauma damages qi and blood, and anesthetic drugs further impair qi circulation, leading to dysfunction of the spleen and stomach, abnormal large intestine conduction, obstruction of the bowel qi, qi stagnation and blood stasis, and suppression of yang qi. The core pathogenesis can be summarized as "qi stagnation and obstruction, and failure of bowel qi to descend." Current TCM treatments for "qi stagnation and obstruction" primarily involve oral decoctions (such as Da Cheng Qi Tang). However, postoperative patients are in a paralyzed state of gastrointestinal function, making oral medications difficult to absorb and utilize, and potentially increasing the burden on the gastrointestinal tract, even inducing risks such as vomiting and aspiration.
[0005] Based on this, the present invention provides a topical preparation (hot compress) that is easy to operate, has a rapid onset of action, is highly safe, and is easy to promote in wards, which can effectively treat paralytic ileus after abdominal tumor surgery. Summary of the Invention
[0006] The present invention aims to provide a hot compress for treating paralytic ileus after abdominal tumor surgery and its preparation method, so as to solve the problems in the background art.
[0007] To achieve the above objectives, the present invention provides the following technical solution:
[0008] A hot compress for treating paralytic ileus after abdominal tumor surgery, wherein the hot compress contains a traditional Chinese medicine composition and a heat-conducting medium, wherein the traditional Chinese medicine composition comprises, by weight, 20-40 parts of Perilla frutescens seeds, 20-40 parts of Magnolia officinalis, 20-40 parts of Citrus aurantium, 20-40 parts of Evodia rutaecarpa, 20-40 parts of Aucklandia lappa and 20-40 parts of Raphanus sativus seeds.
[0009] Furthermore, the traditional Chinese medicine composition, by weight, consists of 30 parts of Perilla Seed, 30 parts of Magnolia Bark, 30 parts of Bitter Orange Peel, 30 parts of Evodia Fruit, 30 parts of Costus Root, and 30 parts of Radish Seed.
[0010] Furthermore, the heat-conducting medium is crude salt, and the mass ratio of the traditional Chinese medicine composition to the crude salt is 1:0.5 to 1:2.
[0011] The above-mentioned method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery includes the following steps:
[0012] S1. Preparation and Pretreatment of Traditional Chinese Medicine Compositions
[0013] Weigh the raw materials according to the weight ratio of the traditional Chinese medicine composition, clean and wash each raw material separately, and then crush them.
[0014] S2, Mixing and Bagging
[0015] The raw materials pretreated in step S1 are mixed evenly with the heat-conducting medium according to the mass ratio, packed into a packaging bag, and sealed to obtain the required heat pack.
[0016] Furthermore, in step S1, for fruits and seeds such as perilla seeds and radish seeds, the outer shell is crushed or ground until cracks appear; for stems and rhizomes such as magnolia bark, bitter orange peel, and costus root, they are cleaned and cut into slices or chunks with a thickness of 2-4 mm; for fruits such as evodia fruit, they are directly crushed into granules.
[0017] Furthermore, in step S2, the packaging bag containing the traditional Chinese medicine composition and the heat-conducting medium is a pure cotton cloth bag.
[0018] Furthermore, the pure cotton bag is 20-30cm long and 15-20cm wide to completely cover the patient's navel and abdominal acupoints. The abdominal acupoints to be covered by the hot compress include Shenque (CV8), Tianshu (ST25), Qihai (CV6), and Guanyuan (CV4).
[0019] The usage method of the above-mentioned hot compress pack for treating paralytic ileus after abdominal tumor surgery includes the following steps: First, spray drinking water on the surface of the hot compress pack, and heat it in a microwave oven on medium heat for 2 - 3 minutes to 60 - 70°C; after taking it out, wrap it with 2 - 3 layers of dry towels, and the surface temperature of the towel after wrapping is 40 - 50°C; finally, apply the hot compress pack hot on the umbilical area around the patient's abdomen, each hot compress for 10 - 30 minutes, 1 - 2 times a day.
[0020] It should be noted that the pharmacological effects and compatibility relationships of the raw materials of the traditional Chinese medicine composition in this hot compress pack are as follows:
[0021] Perilla Seed, Nature, Flavor and Meridian Tropism: Pungent, warm; attributing to the lung and large intestine meridians. Functions and Indications: Descending qi to resolve phlegm, moistening the intestine to relax bowel movements. Used for phlegm congestion and qi reversal, cough and asthma, intestinal dryness and constipation. It is the monarch drug in this formula, descending the lung qi to assist the large intestine in conduction and concurrently moistening the intestine to relax bowel movements.
[0022] Radish Seed, Nature, Flavor and Meridian Tropism: Pungent, sweet, neutral; attributing to the spleen, stomach and lung meridians. Functions and Indications: Promoting digestion to relieve distension, descending qi to resolve phlegm. Used for food stagnation, epigastric and abdominal distending pain, constipation, accumulation and diarrhea, phlegm congestion and asthma. It is the monarch drug in this formula, promoting qi movement to relieve distension and specifically attacking food accumulation and qi stagnation.
[0023] Magnolia Officinalis, Nature, Flavor and Meridian Tropism: Bitter, pungent, warm; attributing to the spleen, stomach, lung and large intestine meridians. Functions and Indications: Drying dampness to eliminate phlegm, descending qi to relieve fullness. Used for dampness stagnating and injuring the middle, epigastric stuffiness and vomiting or diarrhea, food accumulation and qi stagnation, abdominal distension and constipation, phlegm retention and asthma. It is the ministerial drug in this formula, promoting qi movement and guiding stagnation to eliminate abdominal distension.
[0024] Fructus Aurantii, Nature, Flavor and Meridian Tropism: Bitter, pungent, sour, slightly cold; attributing to the spleen, stomach and large intestine meridians. Functions and Indications: Regulating qi to soothe the middle, promoting qi movement to relieve distension. Used for qi stagnation in the chest and hypochondrium, distending pain, indigestion, phlegm retention, visceral ptosis. It is the ministerial drug in this formula, breaking qi to eliminate accumulation and assisting intestinal peristalsis.
[0025] Costus Root, Nature, Flavor and Meridian Tropism: Pungent, bitter, warm; attributing to the spleen, stomach, large intestine, triple energizer and gallbladder meridians. Functions and Indications: Promoting qi movement to stop pain, strengthening the spleen and promoting digestion. Used for chest, hypochondrium, epigastric and abdominal distending pain, tenesmus after diarrhea, indigestion, loss of appetite. It is the adjuvant drug in this formula, promoting qi movement in the stomach and intestines to stop pain.
[0026] Evodia Fruit, Nature, Flavor and Meridian Tropism: Pungent, bitter, hot; slightly toxic; attributing to the liver, spleen, stomach and kidney meridians. Functions and Indications: Dispelling cold to stop pain, descending adverse qi to stop vomiting, assisting yang to stop diarrhea. Used for jueyin headache, cold hernia pain, cold-damp beriberi, abdominal pain during menstruation, epigastric and abdominal distending pain, vomiting and acid regurgitation,五更泄泻. It is the guiding drug in this formula, warming the middle to dispel cold, guiding the drug into the abdomen and assisting yang qi to promote.
[0027] The characteristics of the herbal composition in the hot herbal pack are as follows: Perilla seed and radish seed are the principal herbs, which lower qi, unblock the bowels, and relieve bloating; Magnolia bark and immature bitter orange are the assistant herbs, which promote qi circulation, relieve fullness, and break up stagnation; Costus root is the adjuvant herb, which regulates qi and relieves pain; Evodia fruit is the guiding herb, which warms the middle jiao and guides the medicine to the meridians. The whole formula uses both cold and warm herbs, with warm herbs as the main one, which is in line with the pathogenesis of "deficiency and cold with stagnation" after surgery; the pungent and aromatic herbs are propelled by heat, and their medicinal power penetrates the skin and reaches the affected area directly, thus achieving the effects of promoting qi circulation, lowering qi, unblocking the bowels, warming the middle jiao and dispelling cold.
[0028] The beneficial effects of the technical solution are:
[0029] 1. This invention provides a hot compress for treating paralytic ileus after abdominal tumor surgery, which has the effects of promoting qi circulation, relieving stagnation, clearing the bowels, warming the middle jiao and dispelling cold. In the formula, perilla seed and radish seed lower qi and clear the bowels, magnolia bark and immature bitter orange peel promote qi circulation and relieve fullness, costus root regulates qi and relieves pain, and evodia fruit warms the middle jiao and guides the medicine to the meridians. The six herbs work together to promote qi circulation, relieve stagnation, clear the bowels, and relieve stagnation, which is in line with the core pathogenesis of "qi stagnation" in postoperative paralytic ileus.
[0030] 2. The present invention provides a heat pack for treating paralytic ileus after abdominal tumor surgery. It is applied externally and combines the effects of medicine and heat: the heat can warm and unblock the meridians, dispel cold and relieve pain, while promoting local blood circulation, accelerating the transdermal absorption of the active ingredients of the drug, and acting directly on the abdominal gastrointestinal tract. It has a rapid onset of action and avoids the predicament of oral administration due to gastrointestinal paralysis. It is also non-invasive and painless, and has high patient compliance.
[0031] 3. The present invention provides a method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery. The method uses crude salt as a heat-conducting medium (which provides uniform heating, long-lasting heat retention, and also has the effect of guiding the medicine into the meridians), and employs pure cotton cloth bag sealing and microwave oven heating. This method does not require complicated equipment, is easy to promote and apply in medical institution wards and homes, and the hot compress can be reused 3 to 5 times, making it economical and practical. Detailed Implementation
[0032] The present invention will be further described in detail below with reference to the embodiments:
[0033] Example 1: A hot compress for treating paralytic ileus after abdominal tumor surgery, the hot compress containing a traditional Chinese medicine composition and a heat-conducting medium; wherein, the traditional Chinese medicine composition, by weight, consists of 20-40 parts of Perilla frutescens seeds, 20-40 parts of Magnolia officinalis, 20-40 parts of Citrus aurantium, 20-40 parts of Evodia rutaecarpa, 20-40 parts of Aucklandia lappa, and 20-40 parts of Raphanus sativus seeds; the heat-conducting medium is crude salt, and the mass ratio of the traditional Chinese medicine composition to crude salt is 1:0.5-1:2.
[0034] Example 2: A hot compress for treating paralytic ileus after abdominal tumor surgery, the hot compress containing a traditional Chinese medicine composition and a heat-conducting medium; wherein, the traditional Chinese medicine composition, by weight, consists of 30 parts of Perilla frutescens seeds, 30 parts of Magnolia officinalis, 30 parts of Citrus aurantium, 30 parts of Evodia rutaecarpa, 30 parts of Aucklandia lappa, and 30 parts of Raphanus sativus seeds; the heat-conducting medium is crude salt, and the mass ratio of the traditional Chinese medicine composition to the crude salt is 1:1.
[0035] Example 3: Preparation of the heat pack for treating paralytic ileus after abdominal tumor surgery as described in Example 2, comprising the following steps:
[0036] S1. Raw material preparation and pretreatment
[0037] Weigh the raw materials according to the weight ratio, clean and wash each raw material separately, and crush them; for perilla seeds and radish seeds, crush or grind the outer shell until there are cracks; for magnolia bark, bitter orange peel, and costus root, clean and cut them into slices with a thickness of 2-4mm; for evodia fruit, crush them directly into coarse particles.
[0038] S2, Mixing and Bagging
[0039] The raw materials pretreated in step S1 are mixed evenly with coarse salt at a mass ratio of 1:1, and then placed into a pure cotton cloth bag. The cloth bag is 25cm×20cm in size and can completely cover the patient's navel and abdominal acupoints (Shenque, Tianshu, Qihai and Guanyuan acupoints). The bag is then sewn closed to obtain the required hot compress.
[0040] Example 4: The hot compress prepared in Example 3 was used to treat paralytic ileus after abdominal tumor surgery. The specific method of use is as follows:
[0041] Spray about 1-2 ml of drinking water onto the surface of the hot compress, place it in a microwave oven, and heat on medium heat for 2-3 minutes until the compress reaches a temperature of 60-70℃. After removing it, wrap it with 2-3 layers of dry towels, ensuring it is not too hot to the touch (the temperature of the outer towel should be 40-50℃). Apply the hot compress to the patient's abdomen around the navel. Each application should last 15-30 minutes, 1-2 times daily. Each hot compress can be reused 3-5 times. Replace the compress when the medicinal smell becomes weak or loses its volatility.
[0042] The above descriptions are merely embodiments of the present invention, and common knowledge regarding specific technical solutions or characteristics is not elaborated upon here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.
Claims
1. A thermal compress for treating paralytic ileus obstruction after abdominal tumor surgery, characterized in that, The hot compress contains a traditional Chinese medicine composition and a heat-conducting medium. The traditional Chinese medicine composition, by weight, consists of 20-40 parts of Perilla frutescens seeds, 20-40 parts of Magnolia officinalis, 20-40 parts of Citrus aurantium, 20-40 parts of Evodia rutaecarpa, 20-40 parts of Aucklandia lappa, and 20-40 parts of Raphanus sativus seeds.
2. The thermal compress for treating paralytic ileus obstruction after abdominal tumor surgery according to claim 1, characterized in that, The traditional Chinese medicine composition, by weight, consists of 30 parts of Perilla Seed, 30 parts of Magnolia Bark, 30 parts of Bitter Orange Peel, 30 parts of Evodia Fruit, 30 parts of Costus Root, and 30 parts of Radish Seed.
3. The heat pack for treating paralytic ileus obstruction after abdominal tumor surgery according to claim 1, characterized in that, The heat-conducting medium is crude salt, and the mass ratio of the traditional Chinese medicine composition to the crude salt is 1:0.5 to 1:
2.
4. The method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery according to claim 1, characterized in that, Includes the following steps: S1. Preparation and Pretreatment of Traditional Chinese Medicine Compositions Weigh the raw materials according to the weight ratio of the traditional Chinese medicine composition, clean and wash each raw material separately, and then crush them. S2, Mixing and Bagging The raw materials pretreated in step S1 are mixed evenly with the heat-conducting medium according to the mass ratio, packed into a packaging bag, and sealed to obtain the required heat pack.
5. The method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery according to claim 4, characterized in that, In step S1, for fruits and seeds such as perilla seeds and radish seeds, the outer shell is crushed or ground until it cracks; for stems and rhizomes such as magnolia bark, bitter orange peel, and costus root, they are cleaned and cut into slices or chunks with a thickness of 2-4 mm; for fruits such as evodia fruit, they are directly crushed into granules.
6. The method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery according to claim 4, characterized in that, In step S2, the packaging bag containing the traditional Chinese medicine composition and the heat-conducting medium is a pure cotton cloth bag.
7. The method for preparing a hot compress for treating paralytic ileus after abdominal tumor surgery according to claim 6, characterized in that, The pure cotton bag is 20-30cm long and 15-20cm wide.