An interference-reducing rotating sample loading device for a vial sample

Abstract

The present application relates to sample carrying and detection auxiliary equipment technical field, disclose a kind of interference suppression rotating sample loading device for bottled sample.The device includes rack, rotating sample loading component, drive assembly and fixed component.The device can also be used with laser and detector arranged on the both sides of bottled sample, the incident beam emitted by laser can be obliquely arranged relative to the axis of bottled sample, to reduce the overlapping degree of different transmission beams in detection area;Vibrator can also be arranged at detector, to further improve the interference suppression effect.The present application rotates bottled sample, so that different circumferential regions enter detection path in turn, signal fluctuation caused by uneven bottle wall thickness, surface state difference and local curvature change is averaged, so as to reduce interference, improve stability, repeatability and accuracy in detection process.

Description

Technical Field

[0001] This invention relates to the field of sample carrying and testing auxiliary equipment, specifically to an interference-suppressing rotating sample carrier for bottled samples. This device is suitable for the carrying and rotation adjustment of samples during the testing and analysis of vials, ampoules, and other bottled samples. By rotating the bottled sample around its own axis, it reduces signal fluctuations and interference caused by uneven bottle wall thickness, surface condition differences, or local optical property changes, thereby improving the stability and repeatability of the sample testing process. Background Technology

[0002] Bottled samples are widely used in pharmaceuticals, biology, food, and laboratory analysis. When testing, analyzing, or observing vials, ampoules, and other bottled samples, it is usually necessary to fix the sample vial in the testing position so that the detection signal passes through or acts on the vial to obtain the corresponding result.

[0003] In existing technologies, bottled samples are prone to additional interference during testing due to factors such as uneven bottle walls. Because the bottle wall can form multiple reflection, refraction, and transmission interfaces, the detection signal experiences multiple paths as it passes through the bottle, resulting in interference fringes or signal fluctuations, leading to decreased stability of the test results. Furthermore, bottled samples typically exhibit uneven wall thickness, surface irregularities, and local curvature differences, causing variations in the propagation path of the detection signal at different orientations, thus affecting the test results at different angles and impacting measurement repeatability.

[0004] To mitigate these effects, existing research has primarily employed compensation methods such as altering the incident angle, adding vibrating components, or using backend algorithms. However, these methods often suffer from structural complexity, insufficient adaptability, cumbersome adjustments, or strong dependence on specific detection systems.

[0005] Therefore, there is an urgent need to provide a device with a reasonable structure, strong applicability, and the ability to carry bottled samples and suppress interference, so as to reduce the interference caused by problems such as uneven bottle wall thickness and surface condition differences, and improve the stability, repeatability and accuracy of signals of bottled samples during detection and analysis. Summary of the Invention

[0006] To address the shortcomings of existing technologies, this invention provides an interference suppression rotating sample carrier device for bottled samples.

[0007] Existing research and experimental analysis show that the wall thickness of bottled samples is not uniform. When a light beam or detection signal passes through the bottle, the corresponding propagation path is not exactly the same at different angles, which in turn causes the magnitude of the obtained signal to change with the angle of the bottle.

[0008] The technical solution adopted by the present invention to solve the technical problem is to provide an interference suppression rotating sample carrier for bottled samples, which includes a frame and a rotating sample carrier assembly disposed on the frame.

[0009] The rotating sample carrier is used to carry the bottled sample and drive the bottled sample to rotate around its own axis; the rotating sample carrier is connected to a driving component, which is used to provide rotational power to the rotating sample carrier so that the bottled sample maintains continuous or intermittent rotation during the detection process.

[0010] Furthermore, the device also includes a fixing component for limiting, positioning, or clamping the bottled sample to ensure its stability during rotation and reduce the impact of sway and displacement on the detection process. Based on the existing prototype structure, the drive component can use a motor and belt drive to rotate the base. The sample bottle is fixed to the base and rotates accordingly. Its rotation center can be set as close as possible to the plane of the detection path to reduce additional fluctuations caused by positional deviations.

[0011] Furthermore, the rotating sample carrier assembly can be a turntable, support, bottle holder, roller support, or other load-bearing structure capable of enabling the bottled sample to rotate. The driving assembly can be one or a combination of a motor, reducer, belt drive mechanism, gear drive mechanism, and friction drive mechanism to achieve stable driving of the bottled sample. After the bottled sample is placed in the rotating sample carrier assembly, it rotates around its own axis under the action of the driving assembly. Due to the differences in wall thickness, surface condition, and local curvature at different circumferential positions of the bottle, the bottle wall area entering the detection path changes continuously during the rotation. Therefore, the changes in propagation path, phase changes, and interference intensity fluctuations caused by local bottle wall differences can be broadened and averaged in the time dimension, thereby achieving the purpose of suppressing interference and reducing signal fluctuations.

[0012] Furthermore, the rotating sample carrier of the present invention can not only be used alone, but also in conjunction with other interference suppression measures (vibrator assistance, dual-frequency modulation, etc.) to further improve the overall anti-interference performance.

[0013] Compared with the prior art, the present invention has the following beneficial effects: the present invention can make the bottled sample rotate around its own axis during the detection process, thereby averaging the interference fluctuations caused by uneven bottle wall thickness, surface condition differences and multiple reflections and transmissions, which can effectively reduce the random fluctuations of the detection signal and improve signal stability, measurement repeatability and result accuracy.

[0014] Meanwhile, this invention targets a general category of bottled samples and is not limited to a specific detection principle. Therefore, it is applicable to bottled sample loading, rotation, and interference suppression in various scenarios such as medicine, biology, food, and experimental analysis, and has good versatility and promotional value. Attached Figure Description

[0015] Figure 1 This is a schematic diagram of the principle of the present invention. The figure shows the working method of achieving beam separation by tilting, optical path modulation by rotating the sample, and detection by the modulated signal. The bottled sample is placed on a rotating base, and the laser and detector are located on both sides of the bottled sample, respectively.

[0016] Figure 2 This is a schematic diagram of the multiple reflection paths of the laser beam as it passes through the penicillin vial in this invention. The diagram is divided into four parts: the first sub-diagram from left to right shows the propagation path of DM laser → C2 → C3 → detector; the second sub-diagram from left to right shows the propagation path of DM laser → C2 → C4 → detector; the third sub-diagram from left to right shows the propagation path of DM laser → C1 → C3 → detector; and the fourth sub-diagram from left to right shows the propagation path of DM laser → C1 → C4 → detector. Detailed Implementation

[0017] To further illustrate the principles and structure of the present invention, preferred embodiments of the present invention will now be described in detail with reference to the accompanying drawings.

[0018] This embodiment provides an interference suppression rotating sample carrier device for bottled samples. This device can be applied to the detection, analysis, or observation of bottled samples, and is particularly suitable for suppressing interference caused by uneven bottle wall thickness, surface condition differences, and multiple reflections and transmissions during optical detection of transparent or semi-transparent bottled samples.

[0019] The present invention includes a rotating base, a bottled sample disposed on the rotating base, a laser located on one side of the bottled sample, and a detector located on the other side of the bottled sample.

[0020] Furthermore, the bottled sample is placed vertically on a rotating base, which supports the bottled sample and drives it to rotate around its own axis. The rotating base can be driven by a motor, a reduction gear, a belt drive mechanism, or other conventional drive methods, and the drive structure can be located inside or below the base.

[0021] Furthermore, the bottled sample and the rotating base can be relatively fixed by means of snap-fit, clamping, limiting or friction fit to ensure that the bottled sample will not wobble or detach during rotation.

[0022] Example:

[0023] In this embodiment, the bottled sample is a penicillin vial, but it can also be replaced with vials, ampoules, or other bottled containers with bottle wall structures as needed.

[0024] See Figure 1 The laser and detector are respectively positioned on both sides of the bottled sample, forming a detection path that passes through the sample. In this embodiment, the incident beam emitted by the laser is tilted at a certain angle relative to the axis of the bottled sample, causing beam separation as it passes through the sample. This tilted arrangement reduces the overlap of different transmitted beams within the detection area, minimizing signal distortion and interference caused by multiple beams superimposed.

[0025] Figure 1 The invention also demonstrates a working method for optical path modulation achieved by rotating a bottled sample via a rotating base. During detection, the bottled sample rotates continuously, causing different circumferential positions of the bottle wall to sequentially enter the detection path. This causes the propagation path and interference intensity variations caused by local differences in the bottle wall to continuously change over time, and these variations are averaged during sampling or averaging. Since the sample bottle wall thickness is not uniform throughout, the beam transmission path and signal magnitude differ at different angles. The rotating bottle body of this invention can average out these fluctuations, resulting in a signal that better represents the true internal state of the sample bottle.

[0026] In this embodiment, Figure 1 A vibrator disposed at the detector is also shown. The vibrator drives the detector to vibrate slightly, further altering the equivalent optical path caused by the optical interface on the detector side, thereby working in conjunction with the rotating sample carrier structure to suppress interference fringes. It should be noted that the vibrator is a preferred auxiliary structure in this embodiment; in some implementations, it may be omitted depending on actual needs, and only a rotating base is used to suppress interference introduced by the bottled sample body.

[0027] In this embodiment, the laser can be a tunable semiconductor laser, and the detector can be a photodetector. The detection signal output by the laser passes through the bottled sample and is received by the detector to obtain detection information related to the bottled sample. In this implementation, the laser can employ dual-frequency modulation or other modulation methods. Figure 1 The left side shows a schematic diagram of the dual-frequency modulation principle. However, it should be noted that the core of this invention is to suppress the interference caused by the bottle by rotating the sample carrier. It is not limited to a specific modulation method. As long as there is a scenario where the bottled sample causes interference in the detection path, the rotating sample carrier structure described in this invention can be applied.

[0028] See Figure 2 , Figure 2The diagram illustrates the multiple reflection propagation paths formed when a laser beam passes through a penicillin vial, used to explain the mechanism of interference generated during the detection of the vial sample. Here, C1 and C4 represent the outer wall surface of the vial sample, C2 and C3 represent the inner wall surface, d represents the internal diameter of the vial sample, and θ represents the tilt angle of the incident beam relative to the reference direction. Due to the presence of multiple interfaces within and outside the vial wall, the laser beam undergoes reflection, refraction, and transmission at each interface as it passes through the vial sample, thus forming multiple propagation paths. When these multiple propagation paths are superimposed at the detector end, interference fringes or signal fluctuations are easily formed. Previous analysis has indicated that even with appropriate tilting to achieve partial beam separation, reflection and refraction between the inner and outer interfaces of the vial wall will still cause interference.

[0029] Because actual bottled samples typically exhibit uneven wall thickness, variations in surface flatness, and localized curvature changes during the manufacturing process, different circumferential angles will result in variations in these variations. Figure 2 The equivalent optical path lengths corresponding to the various propagation paths shown are not entirely consistent. Therefore, when the bottled sample is stationary, the detection path always passes through a local area of ​​the bottle wall. The propagation characteristics corresponding to this local area will continuously affect the detection result, causing the measured signal to fluctuate significantly due to local wall thickness or local interface conditions. When the bottled sample rotates around its own axis with the rotating base, different circumferential regions of the bottle wall sequentially enter the detection path. Figure 2 The equivalent optical path and phase relationship of each propagation path shown change continuously over time, so that the interference enhancement or weakening caused by local areas is no longer fixed at the same position, but is broadened and averaged over time, thereby reducing the measurement deviation caused by local differences in the bottle wall and improving signal stability and repeatability.

[0030] In this embodiment, the rotational speed of the rotating base can be set according to the sampling speed, averaging time, and target bottle type of the detection system. The principle is to ensure that the bottled sample rotates through a predetermined angle range within a complete detection cycle, so as to ensure that different circumferential areas can participate in the averaging process.

[0031] In this embodiment, the rotating base can be a disc-type structure, or it can be replaced with a roller-supported structure, a turntable structure, or other sample-carrying structures that allow the bottled sample to rotate around its own axis. The method of fixing the bottled sample can also be adjusted according to the bottle type. The laser and detector are not limited to [specific types]. Figure 1 As shown in the positional relationship, this invention is applicable as long as a detection path can be formed through the bottled sample and interference caused by the bottle can be suppressed.

[0032] The above are merely preferred embodiments of the present invention and are not intended to limit the scope of protection of the present invention. All equivalent structural changes made based on the description and drawings of the present invention are included within the scope of protection of the present invention.

Claims

1. An interference-suppressing rotating sample carrier for bottled samples, characterized in that, It includes a frame, a rotating sample carrier assembly disposed on the frame, a drive assembly connected to the rotating sample carrier assembly, and a fixing assembly disposed on the rotating sample carrier assembly; The rotating sample carrier assembly is used to carry bottled samples, and the driving assembly is used to drive the rotating sample carrier assembly to rotate, so as to drive the bottled samples to rotate continuously or intermittently around their own axis. The fixing component is used to limit, position, or clamp the bottled sample so as to keep the bottled sample stable during rotation; During the detection process, the bottled sample is rotated so that different circumferential regions enter the detection path sequentially. This process averages out signal fluctuations caused by uneven bottle wall thickness, surface condition differences, or local curvature changes, thereby suppressing interference and improving detection stability.

2. The apparatus according to claim 1, characterized in that, The rotating sample carrier assembly is one of a rotating base, turntable, support, bottle holder, or roller support structure.

3. The apparatus according to claim 1, characterized in that, The drive assembly includes a motor and a reduction mechanism or transmission mechanism that is connected to the motor. The transmission mechanism is one or more of a belt drive mechanism, a gear drive mechanism, or a friction drive mechanism.

4. The apparatus according to claim 1, characterized in that, The fixing component adopts one or more of the following: snap-fit, clamping, limiting, positioning groove or friction fit, to achieve relative fixation between the bottled sample and the rotating sample carrier component; and the bottled sample is placed vertically on the rotating sample carrier component, and the rotation center of the bottled sample is set corresponding to the plane of the detection path.

5. The apparatus according to claim 1, characterized in that, It also includes a laser and a detector respectively disposed on both sides of the bottled sample, wherein the laser and the detector form a detection path through the bottled sample; the incident beam emitted by the laser is inclined relative to the axis of the bottled sample so that the beam is separated when passing through the bottled sample, thereby reducing the degree of overlap of different transmitted beams in the detection area.

6. The apparatus according to claim 5, characterized in that, It also includes a vibrator located at the detector, which drives the detector to vibrate slightly to change the equivalent optical path caused by the optical interface on the detector side, and works in conjunction with the rotating sample carrier of the bottled sample to suppress interference fringes.

7. The apparatus according to claim 1, characterized in that, The drive component is used to rotate the bottled sample through a preset angle range within a complete detection cycle, so that different circumferential regions of the bottled sample participate in signal averaging processing; the rotation speed of the rotating base can be set according to the sampling speed, averaging time, and target bottle type of the detection system.

8. The apparatus according to claim 1, characterized in that, The bottled samples are penicillin vials, vials, ampoules, or other transparent or semi-transparent bottled containers.

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