Preparation method of rhinitis treatment with traditional chinese medicine biological component

Abstract

The application discloses a preparation method of a nasal drop with traditional Chinese medicine biological components for treating rhinitis, and comprises the following steps: step one, preparing the first type of nasal drop: frying Semen Xanthii is matched with Magnolia and Bai Zhi to prepare the first type of nasal drop; step two, preparing the second type of nasal drop: using Mentha with Chrysanthemum and Forsythia to prepare the second type of nasal drop; step three, preparing the third type of nasal drop: matching Huangqi with Baishu and Fangfeng to prepare the second type of nasal drop; step four, preparing the finished product: mixing the prepared first type of nasal drop, the second type of nasal drop and the third type of nasal drop to obtain the finished product, wherein the raw materials of the nasal drop are all traditional Chinese medicines, the traditional Chinese medicine preparation has the characteristics of safety and reliability, easy purchase of raw materials, moderate price and easy production, and the traditional Chinese medicine preparation has the characteristics of broad-spectrum treatment of rhinitis, replacement of traditional hormone treatment, reduction of damage of the medicine to the human body and high safety.

Description

Technical Field

[0001] This invention relates to the field of rhinitis treatment technology, specifically to a method for preparing a rhinitis treatment product containing traditional Chinese medicine biological components. Background Technology

[0002] The main harms of rhinitis include difficulty breathing, sleep disorders, increased risk of complications, and long-term uncontrolled rhinitis may affect children's development or increase psychological burden. It is an inflammatory disease of the nasal mucosa. If not intervened in time, it may have a variety of impacts on physical health and quality of life. Rhinitis patients often experience persistent or intermittent nasal congestion due to mucosal swelling or increased secretions, leading to difficulty breathing. Long-term mouth breathing may cause dry throat, mucosal damage, and in severe cases, even lead to a decrease in blood oxygen concentration, causing problems such as headaches and difficulty concentrating. Repeated inflammation may damage the olfactory mucosa of the nasal cavity, leading to a decrease in olfactory sensitivity and affecting appetite and daily life.

[0003] First, the effects of medication may vary depending on the type of rhinitis. For example, for allergic rhinitis, antihistamines such as loratadine tablets and cetirizine hydrochloride can effectively relieve symptoms such as nasal itching, sneezing, and runny nose. For chronic rhinitis, nasal corticosteroids such as budesonide nasal spray and fluticasone propionate nasal spray have good anti-inflammatory, anti-swelling, and nasal ventilation-improving effects.

[0004] However, traditional rhinitis medications have the following drawbacks:

[0005] Traditional rhinitis treatments contain large amounts of antibiotics. The abuse of antibiotics will only lead to prolonged rhinitis and the harm caused by the abuse of antibiotics is extremely great. Summary of the Invention

[0006] The purpose of this invention is to provide a method for preparing a rhinitis treatment containing traditional Chinese medicine biological components, in order to solve the problem mentioned in the background art that traditional rhinitis treatment drugs contain a large amount of antibiotics, and the abuse of antibiotics will only lead to prolonged rhinitis and the great harm of antibiotic abuse.

[0007] To achieve the above objectives, the present invention provides the following technical solution: a method for preparing a rhinitis treatment containing traditional Chinese medicine biological components, comprising the following steps:

[0008] Step 1: Preparation of the first type of nasal drops: Combine roasted Xanthium sibiricum with Magnolia biondii and Angelica dahurica to prepare the first type of nasal drops;

[0009] Step 2: Preparation of the second type of nasal drops: Peppermint, chrysanthemum, and forsythia are used together to prepare the second type of nasal drops;

[0010] Step 3: Preparation of the third type of nasal drops: Astragalus membranaceus is combined with Atractylodes macrocephala and Saposhnikovia divaricata to prepare the second type of nasal drops;

[0011] Step 4: Preparation of semi-finished products: Mix the prepared first type nasal drops, second type nasal drops and third type nasal drops, then add rhubarb, acorus tatarinowii, borneol and evodia rutaecarpa and mix thoroughly to obtain semi-finished products;

[0012] Step 5: Prepare the finished product: Remove impurities from the prepared semi-finished product and determine the volume and quantity to obtain the finished product.

[0013] As a preferred embodiment of the present invention, the specific process for preparing the first type of nasal drops in step one is as follows:

[0014] S1. Ingredients: Weigh out the roasted cocklebur, magnolia flower, and angelica root according to the weight proportions and set aside;

[0015] S2. Volatile oil extraction: Place the weighed fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use.

[0016] S3. Solvent extraction: After weighing out the fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica, extract the volatile oil. Then place the residue in an extraction tank and extract with solvent to obtain a paste for later use.

[0017] S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

[0018] As a preferred embodiment of the present invention, the paste obtained in step S3 is specifically obtained by soaking in 3-10 times the weight of solvent for 0-48 hours, followed by three extractions. The first extraction is performed by heating and refluxing for 3 hours, collecting the first extract, then adding 3-10 times the weight of solvent and heating and refluxing for 2 hours, collecting the second extract, then adding 3-10 times the weight of solvent and heating and refluxing for 2 hours, collecting the third extract, combining the three extracts, filtering, recovering the solvent under reduced pressure, and concentrating to a paste with a relative density of 1.15-1.20 and a temperature of 50-60°C.

[0019] In a preferred embodiment of the present invention, the solvent in step S3 is either ethanol or purified water.

[0020] As a preferred embodiment of the present invention, the specific process for preparing the second type of nasal drops in step two is as follows:

[0021] Step 1: Prepare the powder: Crush the peppermint, chrysanthemum, and forsythia to obtain a powder;

[0022] Step 2, First preparation of medicinal liquid: Add water to the powder, decoct and separate the first medicinal liquid and the residue;

[0023] Step 3, Second preparation of medicinal liquid: Add water to the dregs, decoct and filter out the second medicinal liquid;

[0024] Step 4: Preparation of dried material: Combine the primary and secondary drug solutions, rotary evaporate, and then vacuum dry to obtain the dried material;

[0025] Step 5: Obtain the finished product: After heating the sweetener, add the dried material, stir, add conventional excipients and volatile oil to make ointment, spray or gel for external use, and mix thoroughly to obtain the second type of nasal drops.

[0026] In a preferred embodiment of the present invention, the water added to the powder in step two is in a weight ratio of 8:1.

[0027] As a preferred embodiment of the present invention, the decoction in step two specifically involves decocting at 100-150℃ for 200-240 minutes and then separating the solids; the decoction in step three specifically involves decocting at 80-120℃ for 40-80 minutes and then separating the solids.

[0028] In a preferred embodiment of the present invention, the water added to the dregs in step three is in a weight ratio of 4:1.

[0029] In a preferred embodiment of the present invention, the sweetener in step five is honey.

[0030] As a preferred embodiment of the present invention, the specific process for preparing the third type of nasal drops in step three is as follows:

[0031] S1. Ingredients: Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the weight proportions and set aside;

[0032] S2. Volatile oil extraction: Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use.

[0033] S3. Solvent extraction: After extracting the volatile oil from the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, place the residue in an extraction tank and extract with solvent to obtain a paste for later use.

[0034] S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

[0035] Compared with the prior art, the beneficial effects of the present invention are:

[0036] The raw materials for this nasal drop are all traditional Chinese medicines. Traditional Chinese medicine preparations are safe and reliable, with readily available raw materials, moderate prices, and easy production. In addition, traditional Chinese medicine preparations have a broad-spectrum therapeutic effect on rhinitis, replacing traditional hormone therapy, reducing drug damage to the human body, and are highly safe. Attached Figure Description

[0037] Figure 1 This is a flowchart of the present invention;

[0038] Figure 2 This is a flowchart illustrating the preparation of the first type of nasal drops according to the present invention;

[0039] Figure 3 This is a flowchart illustrating the preparation of the second type of nasal drops according to the present invention;

[0040] Figure 4 This is a flowchart illustrating the preparation of the third nasal drop solution according to the present invention. Detailed Implementation

[0041] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0042] Please see Figure 1-4 This invention provides a method for preparing a rhinitis treatment containing traditional Chinese medicine biological components, comprising the following steps:

[0043] Step 1: Preparation of the first type of nasal drops: Combine roasted Xanthium sibiricum with Magnolia biondii and Angelica dahurica to prepare the first type of nasal drops;

[0044] Step 2: Preparation of the second type of nasal drops: Peppermint, chrysanthemum, and forsythia are used together to prepare the second type of nasal drops;

[0045] Step 3: Preparation of the third type of nasal drops: Astragalus membranaceus is combined with Atractylodes macrocephala and Saposhnikovia divaricata to prepare the second type of nasal drops;

[0046] Step 4: Preparation of semi-finished products: Mix the prepared first type nasal drops, second type nasal drops and third type nasal drops, then add rhubarb, acorus tatarinowii, borneol and evodia rutaecarpa and mix thoroughly to obtain semi-finished products;

[0047] Step 5: Prepare the finished product: Remove impurities from the prepared semi-finished product and determine the volume and quantity to obtain the finished product.

[0048] The specific procedure for preparing the first type of nasal drops in step one is as follows:

[0049] S1. Ingredients: Weigh out the roasted cocklebur, magnolia flower, and angelica root according to the weight proportions and set aside;

[0050] S2. Volatile oil extraction: Place the weighed fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use.

[0051] S3. Solvent extraction: After weighing out the fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica, extract the volatile oil. Then place the residue in an extraction tank and extract with solvent to obtain a paste for later use.

[0052] S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

[0053] The paste obtained by extraction in S3 is specifically obtained by soaking in 3-10 times its weight of solvent for 0-48 hours, followed by three extractions. The first extraction is performed by heating and refluxing for 3 hours, collecting the first extract, then adding 3-10 times its weight of solvent and heating and refluxing for 2 hours, collecting the second extract, and then adding 3-10 times its weight of solvent and heating and refluxing for 2 hours, collecting the third extract, combining the three extracts, filtering, recovering the solvent under reduced pressure, and concentrating to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃.

[0054] The solvent in S3 is either ethanol or purified water.

[0055] The specific process for preparing the second type of nasal drops in step two is as follows:

[0056] Step 1: Prepare the powder: Crush the peppermint, chrysanthemum, and forsythia to obtain a powder;

[0057] Step 2, First preparation of medicinal liquid: Add water to the powder, decoct and separate the first medicinal liquid and the residue;

[0058] Step 3, Second preparation of medicinal liquid: Add water to the dregs, decoct and filter out the second medicinal liquid;

[0059] Step 4: Preparation of dried material: Combine the primary and secondary drug solutions, rotary evaporate, and then vacuum dry to obtain the dried material;

[0060] Step 5: Obtain the finished product: After heating the sweetener, add the dried material, stir, add conventional excipients and volatile oil to make ointment, spray or gel for external use, and mix thoroughly to obtain the second type of nasal drops.

[0061] In step two, water is added to the powder at a weight ratio of 8:1.

[0062] In step two, the decoction is specifically performed at 100-150℃ for 200-240 minutes, followed by separation. In step three, the decoction is specifically performed at 80-120℃ for 40-80 minutes, followed by separation.

[0063] In step three, water is added to the dregs at a weight ratio of 4:1.

[0064] The sweetener used in step five is honey.

[0065] The specific procedure for preparing the third type of nasal drops in step three is as follows:

[0066] S1. Ingredients: Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the weight proportions and set aside;

[0067] S2. Volatile oil extraction: Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use.

[0068] S3. Solvent extraction: After extracting the volatile oil from the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, place the residue in an extraction tank and extract with solvent to obtain a paste for later use.

[0069] S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

[0070] Example 1:

[0071] In this invention, roasted Xanthium sibiricum is combined with Magnolia biondii and Angelica dahurica to prepare a first-class nasal drop. Roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are weighed according to the specified weight proportions and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in a volatile oil extraction tube, soaked in 3 times the amount of water for 3 hours, then heated under reflux for 3 hours. The volatile oil is collected, and the residue and liquid are separated and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in an extraction tank for solvent extraction to obtain a paste. The paste is soaked in 3-10 times its weight of solvent for 0-48 hours, and then extracted 3 times. The first extraction is heated under reflux for 3 hours. Collect the first extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the second extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the third extract, combine the three extracts, filter, recover the solvent under reduced pressure, and concentrate to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃, for later use; add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use, and mix thoroughly to obtain the finished product; use peppermint with chrysanthemum and forsythia to prepare a second type of nasal drops; crush peppermint, chrysanthemum, and forsythia to obtain powder, and add to the powder... After decocting in water, separate the primary liquid and dregs. Add water to the dregs, decoct again, and filter to obtain a secondary liquid. Combine the primary and secondary liquids, evaporate by rotary evaporation, and then vacuum dry to obtain a dried product. Heat the sweetener, add the dried product, stir, and then add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use. Mix thoroughly to obtain a second type of nasal drops. Combine Astragalus membranaceus with Atractylodes macrocephala and Saposhnikovia divaricata to prepare a second type of nasal drops. Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the specified weight. Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata in a volatile oil extraction tube and soak in 3 times the amount of water for 3 days. In the early stages, the herbs were heated under reflux for 3 hours, and the volatile oil was collected. The residue and liquid were separated and set aside for later use. The volatile oil of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata were extracted, and the residue was placed in an extraction tank for solvent extraction to obtain a paste for later use. Conventional excipients and volatile oil were added to prepare ointments, sprays, or gels for external use. The mixture was thoroughly mixed to obtain the finished product. 30% of the first type of nasal drops, 40% of the second type of nasal drops, and 30% of the third type of nasal drops were mixed and then Rheum palmatum, Acorus tatarinowii, Borneol, and Evodia rutaecarpa were added and thoroughly mixed to obtain a semi-finished product. The semi-finished product was then purified to remove impurities and determined to a fixed volume and quantity to obtain the finished product.

[0072] Example 2:

[0073] In this invention, roasted Xanthium sibiricum is combined with Magnolia biondii and Angelica dahurica to prepare a first-class nasal drop. Roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are weighed according to the specified weight proportions and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in a volatile oil extraction tube, soaked in 3 times the amount of water for 3 hours, then heated under reflux for 3 hours. The volatile oil is collected, and the residue and liquid are separated and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in an extraction tank for solvent extraction to obtain a paste. The paste is soaked in 3-10 times its weight of solvent for 0-48 hours, and then extracted 3 times. The first extraction is heated under reflux for 3 hours. Collect the first extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the second extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the third extract, combine the three extracts, filter, recover the solvent under reduced pressure, and concentrate to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃, for later use; add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use, and mix thoroughly to obtain the finished product; use peppermint with chrysanthemum and forsythia to prepare a second type of nasal drops; crush peppermint, chrysanthemum, and forsythia to obtain powder, and add to the powder... After decocting in water, separate the primary liquid and dregs. Add water to the dregs, decoct again, and filter to obtain a secondary liquid. Combine the primary and secondary liquids, evaporate by rotary evaporation, and then vacuum dry to obtain a dried product. Heat the sweetener, add the dried product, stir, and then add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use. Mix thoroughly to obtain a second type of nasal drops. Combine Astragalus membranaceus with Atractylodes macrocephala and Saposhnikovia divaricata to prepare a second type of nasal drops. Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the specified weight. Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata in a volatile oil extraction tube and soak in 3 times the amount of water for 3 days. In the early stages, the herbs were heated under reflux for 3 hours, and the volatile oil was collected. The residue and liquid were separated and set aside for later use. The volatile oil of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata were extracted, and the residue was placed in an extraction tank for solvent extraction to obtain a paste for later use. Conventional excipients and volatile oil were added to make ointments, sprays, or gels for external use. The mixture was thoroughly mixed to obtain the finished product. 20% of the first type of nasal drops, 40% of the second type of nasal drops, and 40% of the third type of nasal drops were mixed and then Rheum palmatum, Acorus tatarinowii, Borneol, and Evodia rutaecarpa were added and thoroughly mixed to obtain a semi-finished product. The semi-finished product was then purified to remove impurities and determined to a fixed volume and quantity to obtain the finished product.

[0074] Example 3:

[0075] In this invention, roasted Xanthium sibiricum is combined with Magnolia biondii and Angelica dahurica to prepare a first-class nasal drop. Roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are weighed according to the specified weight proportions and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in a volatile oil extraction tube, soaked in 3 times the amount of water for 3 hours, then heated under reflux for 3 hours. The volatile oil is collected, and the residue and liquid are separated and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in an extraction tank for solvent extraction to obtain a paste. The paste is soaked in 3-10 times its weight of solvent for 0-48 hours, and then extracted 3 times. The first extraction is heated under reflux for 3 hours. Collect the first extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the second extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the third extract, combine the three extracts, filter, recover the solvent under reduced pressure, and concentrate to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃, for later use; add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use, and mix thoroughly to obtain the finished product; use peppermint with chrysanthemum and forsythia to prepare a second type of nasal drops; crush peppermint, chrysanthemum, and forsythia to obtain powder, and add to the powder... After decocting in water, separate the primary liquid and dregs. Add water to the dregs, decoct again, and filter to obtain a secondary liquid. Combine the primary and secondary liquids, evaporate by rotary evaporation, and then vacuum dry to obtain a dried product. Heat the sweetener, add the dried product, stir, and then add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use. Mix thoroughly to obtain a second type of nasal drops. Combine Astragalus membranaceus with Atractylodes macrocephala and Saposhnikovia divaricata to prepare a second type of nasal drops. Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the specified weight. Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata in a volatile oil extraction tube and soak in 3 times the amount of water for 3 days. In the early stages, the mixture was heated under reflux for 3 hours, and the volatile oil was collected. The residue and liquid were separated and set aside for later use. The volatile oil of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata were extracted, and the residue was placed in an extraction tank for solvent extraction to obtain a paste for later use. Conventional excipients and volatile oil were added to prepare ointments, sprays, or gels for external use. The mixture was thoroughly mixed to obtain the finished product. 40% of the first type of nasal drops, 40% of the second type of nasal drops, and 20% of the third type of nasal drops were mixed and then Rheum palmatum, Acorus tatarinowii, Borneol, and Evodia rutaecarpa were added and thoroughly mixed to obtain a semi-finished product. The semi-finished product was then purified to remove impurities and determined to a fixed volume and quantity to obtain the finished product.

[0076] Example 4:

[0077] In this invention, roasted Xanthium sibiricum is combined with Magnolia biondii and Angelica dahurica to prepare a first-class nasal drop. Roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are weighed according to the specified weight proportions and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in a volatile oil extraction tube, soaked in 3 times the amount of water for 3 hours, then heated under reflux for 3 hours. The volatile oil is collected, and the residue and liquid are separated and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in an extraction tank for solvent extraction to obtain a paste. The paste is soaked in 3-10 times its weight of solvent for 0-48 hours, and then extracted 3 times. The first extraction is heated under reflux for 3 hours. Collect the first extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the second extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the third extract, combine the three extracts, filter, recover the solvent under reduced pressure, and concentrate to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃, for later use; add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use, and mix thoroughly to obtain the finished product; use peppermint with chrysanthemum and forsythia to prepare a second type of nasal drops; crush peppermint, chrysanthemum, and forsythia to obtain powder, and add to the powder... After decocting in water, separate the primary liquid and dregs. Add water to the dregs, decoct again, and filter to obtain a secondary liquid. Combine the primary and secondary liquids, evaporate by rotary evaporation, and then vacuum dry to obtain a dried product. Heat the sweetener, add the dried product, stir, and then add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use. Mix thoroughly to obtain a second type of nasal drops. Combine Astragalus membranaceus with Atractylodes macrocephala and Saposhnikovia divaricata to prepare a second type of nasal drops. Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the specified weight. Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata in a volatile oil extraction tube and soak in 3 times the amount of water for 3 days. In the early stages, the herbs were heated under reflux for 3 hours, and the volatile oil was collected. The residue and liquid were separated and set aside for later use. The volatile oil of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata were extracted, and the residue was placed in an extraction tank for solvent extraction to obtain a paste for later use. Conventional excipients and volatile oil were added to make ointments, sprays, or gels for external use. The mixture was thoroughly mixed to obtain the finished product. 25% of the first type of nasal drops, 25% of the second type of nasal drops, and 50% of the third type of nasal drops were mixed and then Rheum palmatum, Acorus tatarinowii, Borneol, and Evodia rutaecarpa were added and thoroughly mixed to obtain a semi-finished product. The semi-finished product was then purified to remove impurities and determined to a fixed volume and quantity to obtain the finished product.

[0078] Example 5:

[0079] In this invention, roasted Xanthium sibiricum is combined with Magnolia biondii and Angelica dahurica to prepare a first-class nasal drop. Roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are weighed according to the specified weight proportions and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in a volatile oil extraction tube, soaked in 3 times the amount of water for 3 hours, then heated under reflux for 3 hours. The volatile oil is collected, and the residue and liquid are separated and set aside. The weighed roasted Xanthium sibiricum, Magnolia biondii, and Angelica dahurica are placed in an extraction tank for solvent extraction to obtain a paste. The paste is soaked in 3-10 times its weight of solvent for 0-48 hours, and then extracted 3 times. The first extraction is heated under reflux for 3 hours. Collect the first extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the second extract, add 3-10 times its weight of solvent, heat under reflux for 2 hours, collect the third extract, combine the three extracts, filter, recover the solvent under reduced pressure, and concentrate to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃, for later use; add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use, and mix thoroughly to obtain the finished product; use peppermint with chrysanthemum and forsythia to prepare a second type of nasal drops; crush peppermint, chrysanthemum, and forsythia to obtain powder, and add to the powder... After decocting in water, separate the primary liquid and dregs. Add water to the dregs, decoct again, and filter to obtain a secondary liquid. Combine the primary and secondary liquids, evaporate by rotary evaporation, and then vacuum dry to obtain a dried product. Heat the sweetener, add the dried product, stir, and then add conventional excipients and volatile oils to prepare ointments, sprays, or gels for external use. Mix thoroughly to obtain a second type of nasal drops. Combine Astragalus membranaceus with Atractylodes macrocephala and Saposhnikovia divaricata to prepare a second type of nasal drops. Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the specified weight. Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata in a volatile oil extraction tube and soak in 3 times the amount of water for 3 days. In the early stages, the herbs were heated under reflux for 3 hours, and the volatile oil was collected. The residue and liquid were separated and set aside for later use. The volatile oil of Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata were extracted, and the residue was placed in an extraction tank for solvent extraction to obtain a paste for later use. Conventional excipients and volatile oil were added to make ointments, sprays, or gels for external use. The mixture was thoroughly mixed to obtain the finished product. 40% of the first type of nasal drops, 10% of the second type of nasal drops, and 50% of the third type of nasal drops were mixed and then Rheum palmatum, Acorus tatarinowii, Borneol, and Evodia rutaecarpa were added and thoroughly mixed to obtain a semi-finished product. The semi-finished product was then purified to remove impurities and determined to a fixed volume and quantity to obtain the finished product.

[0080] Using a sample size of 100, the treatment results are shown in Table 1:

[0081]

[0082] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A method for preparing a treatment for rhinitis containing traditional Chinese medicine biological components, characterized in that, Includes the following steps: Step 1: Preparation of the first type of nasal drops: Combine roasted Xanthium sibiricum with Magnolia biondii and Angelica dahurica to prepare the first type of nasal drops; Step 2: Preparation of the second type of nasal drops: Peppermint, chrysanthemum, and forsythia are used together to prepare the second type of nasal drops; Step 3: Preparation of the third type of nasal drops: Astragalus membranaceus is combined with Atractylodes macrocephala and Saposhnikovia divaricata to prepare the second type of nasal drops; Step 4: Preparation of semi-finished products: Mix the prepared first type nasal drops, second type nasal drops and third type nasal drops, then add rhubarb, acorus tatarinowii, borneol and evodia rutaecarpa and mix thoroughly to obtain semi-finished products; Step 5: Prepare the finished product: Remove impurities from the prepared semi-finished product and determine the volume and quantity to obtain the finished product.

2. The method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 1, characterized in that: The specific process for preparing the first type of nasal drops in step one is as follows: S1. Ingredients: Weigh out the roasted cocklebur, magnolia flower, and angelica root according to the weight proportions and set aside; S2. Volatile oil extraction: Place the weighed fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use. S3. Solvent extraction: After weighing out the fried Xanthium sibiricum, Magnolia biondii, and Angelica dahurica, extract the volatile oil. Then place the residue in an extraction tank and extract with solvent to obtain a paste for later use. S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

3. The method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 2, characterized in that: The paste obtained in S3 is specifically obtained by soaking in 3-10 times its weight of solvent for 0-48 hours, followed by three extractions. The first extraction is performed by heating and refluxing for 3 hours, collecting the first extract, then adding 3-10 times its weight of solvent and heating and refluxing for 2 hours, collecting the second extract, and then adding 3-10 times its weight of solvent and heating and refluxing for 2 hours, collecting the third extract, combining the three extracts, filtering, recovering the solvent under reduced pressure, and concentrating to a paste with a relative density of 1.15-1.20 and a temperature of 50-60℃.

4. The method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 2, characterized in that: The solvent in S3 is either ethanol or purified water.

5. The method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 1, characterized in that: The specific process for preparing the second type of nasal drops in step two is as follows: Step 1: Prepare the powder: Crush the peppermint, chrysanthemum, and forsythia to obtain a powder; Step 2, First preparation of medicinal liquid: Add water to the powder, decoct and separate the first medicinal liquid and the residue; Step 3, Second preparation of medicinal liquid: Add water to the dregs, decoct and filter out the second medicinal liquid; Step 4: Preparation of dried material: Combine the primary and secondary drug solutions, rotary evaporate, and then vacuum dry to obtain the dried material; Step 5: Obtain the finished product: After heating the sweetener, add the dried material, stir, add conventional excipients and volatile oil to make ointment, spray or gel for external use, and mix thoroughly to obtain the second type of nasal drops.

6. The method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 5, characterized in that: In step two, water is added to the powder at a weight ratio of 8:

1.

7. A method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 5, characterized in that: In step two, the decoction is specifically performed at 100-150℃ for 200-240 minutes, followed by separation. In step three, the decoction is specifically performed at 80-120℃ for 40-80 minutes, followed by separation.

8. A method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 5, characterized in that: In step three, the water added to the dregs is in a weight ratio of 4:

1.

9. A method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 5, characterized in that: The sweetener used in step five is honey.

10. A method for preparing a rhinitis treatment containing traditional Chinese medicine biological components according to claim 1, characterized in that: The specific process for preparing the third type of nasal drops in step three is as follows: S1. Ingredients: Weigh out Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata according to the weight proportions and set aside; S2. Volatile oil extraction: Place the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata into a volatile oil extraction tube, add 3 times the amount of water and soak for 3 hours, then heat under reflux for 3 hours, collect the volatile oil, and separate the residue and liquid for later use. S3. Solvent extraction: After extracting the volatile oil from the weighed Astragalus membranaceus, Atractylodes macrocephala, and Saposhnikovia divaricata, place the residue in an extraction tank and extract with solvent to obtain a paste for later use. S4. Add excipients: Add conventional excipients and volatile oils to make ointments, sprays or gels for external use, and mix thoroughly to obtain the finished product.

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