Method for extracting menotrophin from urine of postmenopausal women
By combining modified kaolin with chitosan and modifying it with aminosilanes, along with a multi-step process using perlite, the problem of low yield and purity of urinary gonadotropin extraction was solved, achieving efficient urinary gonadotropin extraction.
CN122167560APending Publication Date: 2026-06-09河北伟宸生物制品有限公司
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Patent Information
- Application Number
- CN202610309372.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-03-13
- Publication Date
- 2026-06-09
AI Technical Summary
Technical Problem
Existing technologies for extracting urinary gonadotropins from the urine of postmenopausal women have low yields and low purity, making efficient adsorption impossible.
Method used
Modified kaolin is compounded with chitosan and then modified with aminosilanes to form covalent bonds and π-π interactions, which improves adsorption capacity and dispersibility. Combined with multi-step processing of perlite, high yield and high purity extraction can be achieved.
Benefits of technology
It significantly improved the yield and purity of urinary gonadotropin, achieving a yield of 87.9%~99.8% and a purity of 94.3%~99.8%.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention relates to the technical field of biology, and provides a method for extracting menotrophin from urine of a postmenopausal woman, which comprises the following steps: S1, filtering the urine of the postmenopausal woman, adjusting the pH value to 4-4.5, adding modified kaolin, mixing, adding perlite, mixing, standing, filtering and drying to obtain a kaolin adsorbate; s2, a desorption solution is added into the kaolin adsorbate, after secondary desorption, filtrate obtained through two times is combined, the pH value is adjusted to 8.2-8.7, then standing is conducted, perlite is added for mixing, standing is conducted, filtration and ultrafiltration are conducted to obtain a concentrated solution, after the pH value of the concentrated solution is adjusted to 5-5.5, acetone is added for mixing, standing is conducted, suction filtration is conducted, dehydration is conducted with acetone, and screening and drying are conducted to obtain menotrophin; the modified kaolin is obtained by compounding kaolin with chitosan and then modifying with amino silane. According to the technical scheme, the problems of low extraction yield and low purity of menotrophin in related technologies are solved.
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