A traditional Chinese medicine composition for improving back perspiration, and a preparation method and application thereof

Abstract

This invention discloses a traditional Chinese medicine composition for improving back sweating, its preparation method, and its application, belonging to the technical field of traditional Chinese medicine compound preparations. The composition of this invention is formulated by combining Angelica pubescens, ginseng, dried plum, galangal, and peppermint in specified weight parts, with a preferred ratio of 15 parts Angelica pubescens, 6 parts ginseng, 12 parts dried plum, 6 parts galangal, and 10 parts peppermint. This invention targets the pathogenesis of compensatory sweating of the back caused by internal obstruction of cold pathogens and compression of the space for qi and blood circulation by the viscera, through hypothalamic regulation. It follows the principles of warming and dispersing cold pathogens, relaxing the viscera, regulating qi, and astringing sweat and consolidating body fluids. This invention also provides a standardized decoction preparation process, with strong synergistic effects of the formula, which can specifically improve symptoms such as spontaneous sweating, excessive sweating during activity, and cold and damp back. The formula is concise and easy to prepare, with significant clinical application value.

Description

Technical Field

[0002] This invention belongs to the field of traditional Chinese medicine compound preparation technology, specifically relating to a traditional Chinese medicine composition for improving back sweating, its preparation method and application. Background Technology

[0004] Abnormal sweating on the back is a very common and persistent symptom of bodily imbalance in clinical practice. It is mainly manifested as spontaneous sweating on the back, profuse sweating after slight activity, and a cold, sticky feeling on the back. It is often accompanied by symptoms such as tightness in the back, aversion to cold, deficiency and coldness of internal organs, stagnation of Qi, and weakness of limbs. Symptoms are significantly aggravated in cold and rainy weather.

[0005] Current TCM clinical practice primarily diagnoses and treats cases from conventional perspectives such as qi deficiency and instability, disharmony between ying and wei, yin deficiency with excessive fire, and damp-heat accumulation. Prescriptions often include herbs such as astragalus, ephedra root, wheat bran, oyster shell, and gallnut, with treatment strategies mainly focused on tonifying qi and consolidating the exterior, astringing and stopping sweating, or nourishing yin and clearing heat. However, current techniques have significant shortcomings and deficiencies:

[0006] First, traditional diagnosis is mostly limited to the superficial manifestations of the body's defenses and the deficiency of Qi and Yin, without paying attention to the underlying pathogenesis of internal organ contraction and limited space for the circulation of Qi and blood caused by the invasion of cold pathogens.

[0007] Secondly, conventional treatments often involve simply consolidating the surface and stopping sweating, which only addresses the symptoms at the level of skin pores. This does not loosen the cold pathogen's binding and constricting effect on the internal organs, nor does it restore the normal circulation of qi and blood. It treats the symptoms but not the root cause, and the symptoms are prone to recurrence after stopping the medication.

[0008] Third, existing prescriptions lack corresponding formulations that address the issues of cold pathogens drawing in internal organs, limited space for the circulation of qi and blood, and compensatory heat dissipation in the back caused by the expansion of qi and blood after activity. Therefore, the treatment is not targeted enough and it is difficult to achieve both symptomatic relief and root cause treatment.

[0009] Based on the gaps and deficiencies in existing technologies, this invention combines traditional Chinese medicine pathogenesis theory with modern physiological mechanisms to provide a well-formulated, pathogenesis-matched, and effective traditional Chinese medicine composition for improving this type of abnormal back sweating. Summary of the Invention

[0011] I. Traditional Chinese Medicine Compositions

[0012] A traditional Chinese medicine composition for improving back sweating, made from the following raw materials in parts by weight:

[0013] Angelica pubescens 5-30 parts, ginseng 3-15 parts, dried plum 6-20 parts, galangal 3-15 parts, mint 5-20 parts.

[0014] The preferred ratio is: 15 parts Angelica pubescens, 6 parts ginseng, 12 parts dried plum, 6 parts Alpinia galanga, and 10 parts mint.

[0015] II. In-depth explanation of the core pathogenesis

[0016] The pathogenesis of abnormal sweating on the back is as follows:

[0017] When cold pathogens invade the body, they obstruct the internal organs. The cold nature causes contraction, stagnation, and shrinkage, which easily leads to the contraction of the internal organs and the tightening of their cavities. This compresses the physiological space for the rise, fall, flow, and circulation of qi and blood within the internal organs, and significantly reduces the natural range of qi and blood movement.

[0018] When the human body is at rest, the flow of qi and blood is smooth. Even if the space of the internal organs is limited, the body can still maintain basic homeostasis and there is no obvious abnormal sweating.

[0019] When the body walks, works, or engages in limb activities, the flow of blood and qi throughout the body accelerates, qi rises and expands, and physiological metabolic internal heat is generated at the same time.

[0020] Because the internal organs are constricted and restricted by cold pathogens, there is insufficient space for the internal qi and blood to be contained, making it difficult to bear the expansion of qi and blood and the accumulation of internal heat after activity.

[0021] To maintain the body's yin-yang balance and internal environment stability, the body activates a compensatory heat dissipation regulation mechanism through the hypothalamus thermoregulation center. This selectively opens the skin pores on the back, opening the pores and accelerating sweat secretion and excretion. Excess internal heat is removed and the bloated qi is relieved through sweating, resulting in the characteristic manifestations of profuse sweating on the back during activity, a cold and sticky back, and a lingering and difficult-to-cure course of the disease.

[0022] Traditional treatments that invigorate qi and astringe sweat often simply close the pores on the skin surface and block the leakage of sweat, without removing the cold pathogens in the internal organs or relaxing the contraction of the internal organs to restore the normal circulation of qi and blood. Forcibly astringing sweat can easily cause internal swelling, with qi and blood and stagnant heat unable to be released, making the cold stagnation more severe and the qi stagnation deeper, forming a cycle of recurring symptoms.

[0023] III. Supporting Evidence from Modern Pharmacological Mechanisms

[0024] From the perspective of modern medical mechanisms, the obstruction of internal cold can induce the contraction of smooth muscles and visceral tissues, compressing the space for the circulation of qi and blood in the body. At the same time, it affects the hypothalamus-thermoregulation-sympathetic nerve regulation pathway, causing abnormally high sensitivity of the sweat glands in the back skin. After the body's activity, metabolic heat production increases and the load on the circulation of qi and blood rises, making it difficult for internal heat and qi pressure to dissipate normally. As a result, compensatory sweating and heat dissipation are formed through the pores of the back, which is consistent with the pathogenesis and mechanism of action of this invention.

[0025] IV. The Principle of Matching Rulers, Ministers, Assistants, and Envoys

[0026] This invention is based on the pathological principles of cold pathogens contracting internal organs, compressing the space for the circulation of qi and blood, causing qi and blood to expand after activity, and regulating compensatory sweating in the back via the hypothalamus. The principal, assistant, adjuvant, and guide relationships are as follows:

[0027] Chief herb: 15 parts of Angelica pubescens

[0028] It has a unique active and warming effect, entering the kidney and bladder meridians. It is good at dispersing deep-seated cold and stagnation, warming and unblocking the internal organs and meridians. It can break through the cold evil that has lingered in the internal organs, relieve the contraction and tension of the cold evil on the five internal organs and six bowels, relax the cavities of the internal organs, and restore the normal operation and circulation space of the internal organs' qi and blood.

[0029] The following are the ingredients: 6 parts galangal, 12 parts dried plum.

[0030] Alpinia galanga is pungent and warm, warms the middle jiao, warms the internal organs and dispels cold, warms and restores the yang qi of the internal organs, dispels internal cold and turbidity, reduces the cold evil from once again drawing and confining the internal organs, and stabilizes the relaxed state of the internal organs.

[0031] Ume plums are sour and astringent, and can help to astringe and retain fluids. They are effective against the open pores and excessive loss of body fluids on the back caused by hypothalamic compensatory regulation. They can help to astringe sweat, consolidate the skin and improve the symptoms of sweating on the back.

[0032] Adjuvant herbs: 6 parts ginseng, 10 parts peppermint

[0033] Ginseng invigorates qi and strengthens the body's resistance, warms and replenishes the vital energy of the internal organs, enhances the organs' ability to resist cold and pathogens, promotes the smooth flow of qi and blood, and makes it less likely to cause stagnation and bloating due to activity.

[0034] Peppermint is light and refreshing, promoting the smooth flow of Qi throughout the body, opening the pores on the skin surface, and facilitating the orderly release of internal heat, reducing the pressure of internal heat accumulation, and decreasing the degree of compensatory sweating on the back. At the same time, the warming and drying properties of the herbs in the formula ensure that they are warm and dispersing without harming Yin, and regulating without depleting the body's vital energy.

[0035] The overall treatment logic is as follows: dispel cold pathogens from the internal organs → loosen the contraction of the internal organs → restore the space for the circulation of qi and blood → regulate qi and relieve internal heat → consolidate the skin and stop sweating to treat the symptoms. The formulation and combination are clearly hierarchical and highly consistent with the pathogenesis of the disease, and have good clinical application value.

[0036] V. Efficacy and Indications

[0037] Efficacy: Warms and dispels cold pathogens from the internal organs, loosens the contractions of the internal organs, restores the circulation space of qi and blood, regulates qi, and astringes sweat and consolidates body fluids.

[0038] Indications: It is used for abnormal sweating of the back caused by internal obstruction of cold pathogens, compression of the space for the circulation of qi and blood by the viscera and the expansion of qi and blood after the body's activity, and the back's compensatory heat dissipation regulated by the hypothalamus.

[0039] Symptoms include: spontaneous sweating on the back, profuse sweating on the back after slight activity, cold and sticky back, tightness and heaviness in the back, aversion to cold and cold limbs, deficiency and cold of internal organs, stagnation of Qi, weakness and fatigue, and worsening of symptoms on rainy days.

[0040] VI. Preparation Method

[0041] 1. Weigh out the following ingredients by weight: Angelica pubescens, ginseng, dried plum, galangal, and mint. Wash them and remove any impurities.

[0042] 2. Add Angelica pubescens, ginseng, dried plum, and galangal to 8 times the total weight of the herbs in water and soak at room temperature for 30 minutes;

[0043] 3. After bringing to a boil over high heat, reduce to a simmer and cook for 20 minutes.

[0044] 4. Add the mint and continue simmering over low heat for 5 minutes;

[0045] 5. Turn off the heat and let it stand for 5 minutes. Filter out the liquid to obtain the decoction.

[0046] VII. Application

[0047] The application of the traditional Chinese medicine composition of the present invention in the preparation of medicines for treating abnormal sweating, spontaneous sweating, and cold and damp sweating of the back caused by cold pathogens obstructing the internal organs, the internal organs contracting and compressing the space for the circulation of qi and blood, and the hypothalamus regulating and compensating for heat dissipation.

[0048] Clinical Examples

[0049] Example 1

[0050] The patient was a 43-year-old male who had experienced abnormal back sweating for 3 years. Sweating was not noticeable at rest, but became profuse with even slight walking or activity. He also experienced a cold, damp, and heavy feeling in his back, along with aversion to cold and fatigue. The diagnosis was that cold pathogens were drawing in from the internal organs, restricting the flow of qi and blood, leading to compensatory sweating after activity. One dose was administered daily, divided into morning and evening doses, according to the preparation method of this invention, for 28 consecutive days. After treatment, the cold pathogens in the internal organs were dispelled, the contraction of the internal organs was relieved, the flow of qi and blood was restored, the back sweating symptoms completely disappeared, and the aversion to cold and dampness subsided. No recurrence was observed during a 3-month follow-up, indicating clinical cure.

[0051] Example 2

[0052] The patient was a 36-year-old female who had experienced significant daytime back sweating and nighttime back sweating for one year, accompanied by back tightness, spleen and stomach deficiency and cold, and aversion to cold and preference for warmth. The diagnosis was cold stagnation in the internal organs, limited space, and compensatory heat leakage due to stagnant Qi. A decoction was prepared according to the method of this invention, one dose daily for 21 consecutive days. After treatment, the nighttime sweating stopped, daytime back sweating significantly decreased, the back tightness and heaviness were relieved, and the Qi circulation and heat dissipation regulation of the internal organs returned to normal, demonstrating clinical efficacy.

[0053] Example 3

[0054] The patient was a 48-year-old male who suffered from chronic weakness and aversion to cold. He did not sweat profusely at rest, but experienced significant sweating on his back after slight exertion. His condition worsened on rainy days and after exposure to cold stimuli. He also experienced heaviness and fatigue in his limbs. The diagnosis was that cold pathogens were drawing in from the internal organs, compressing the circulation of qi and blood. After taking one dose of the decoction of this invention daily for 25 consecutive days, the amount and frequency of back sweating decreased significantly, the aversion to cold and heaviness subsided, and there was no compensatory back sweating after physical activity. The treatment was clinically effective.

Claims

1. A traditional Chinese medicine composition for improving back sweating, characterized in that, Made from the following parts by weight of active pharmaceutical ingredient: Angelica pubescens 5-30 parts, ginseng 3-15 parts, dried plum 6-20 parts, galangal 3-15 parts, mint 5-20 parts.

2. The traditional Chinese medicine composition for improving back sweating according to claim 1, characterized in that, Made from the following parts by weight of active pharmaceutical ingredient: Angelica pubescens 15 parts, ginseng 6 parts, dried plum 12 parts, galangal 6 parts, mint 10 parts.

3. The traditional Chinese medicine composition for improving back sweating according to claim 1, characterized in that, The traditional Chinese medicine composition is an oral decoction.

4. A method for preparing the traditional Chinese medicine composition for improving back sweating as described in claim 1, characterized in that, Includes the following steps: (1) Weigh out Angelica pubescens, ginseng, dried plum, galangal and mint by weight, wash and remove impurities and set aside; (2) Soak Angelica pubescens, ginseng, dried plum and galangal in 8 times the amount of water for 30 minutes, bring to a boil over high heat and then simmer over low heat for 20 minutes; (3) Add mint and continue to simmer for 5 minutes. After standing, filter out the decoction.

5. The application of the traditional Chinese medicine composition according to claim 1 in the preparation of a medicine for treating abnormal sweating of the back caused by cold pathogens obstructing the internal organs, the internal organs contracting and compressing the space for the flow of qi and blood, and the hypothalamus regulating and compensating for heat dissipation.