Marker for assessing quality of ivm-derived embryos and use thereof

By identifying and recording specific morphodynamic parameters of IVM embryos, an image data evaluation method was established, which solved the problem of insufficient accuracy in IVM embryo evaluation, improved the prediction of blastocyst formation and chromosome euploidy, and enhanced the effectiveness of assisted reproductive technology.

CN122290992APending Publication Date: 2026-06-26TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
Filing Date
2026-03-12
Publication Date
2026-06-26

AI Technical Summary

Technical Problem

In existing technologies, the morphodynamic characteristics of IVM-derived embryos lack uniformity and standardization, resulting in insufficient assessment accuracy and affecting the outcome of assisted reproductive technologies.

Method used

By labeling and recording the morphodynamic parameters t2, t9, S2, t9–t7, t9–t8, or tSB–t9 of IVM-derived embryos, the relationship between these parameters and embryo blastocyst formation and chromosome euploidy was identified, a specific assessment method was established, and in vitro assessment was performed using image data.

Benefits of technology

It provides more accurate quality assessment of IVM-derived embryos, improves the predictive ability of blastocyst formation potential and chromosome euploidy, and improves the clinical outcomes of assisted reproductive technologies.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN122290992A_ABST
    Figure CN122290992A_ABST
Patent Text Reader

Abstract

This invention relates to the fields of biomedical engineering and embryo quality assessment, and particularly to a biomarker for assessing the quality of IVM-derived embryos and its application. The biomarker includes time point parameters t2 and t9 of the IVM-derived embryos, and time interval parameters S2, t9–t7, t9–t8, or tSB–t9. A method for assessing the quality of IVM-derived embryos based on the aforementioned biomarker has been established. This method combines non-invasive temporal imaging technology with morphodynamic multi-parameter analysis, providing a reliable tool for assessing the blastocyst formation potential and chromosomal euploidy of IVM-derived embryos in clinical practice, thus potentially expanding the application of IVM technology in assisted reproductive technology.
Need to check novelty before this filing date? Find Prior Art