Fibrinolytic Pseudomonas spp. QMS71 from mangrove wetlands and its application

By isolating and screening the wetland pseudobacterium QMS71 strain from mangrove wetlands, the problem of scarce microbial resources in existing technologies has been solved, and stable fibrin degradation under mesophilic and high-salt environments has been achieved, thus expanding the microbial sources for fibrin degradation research.

CN122303083APending Publication Date: 2026-06-30JIANGSU OCEAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU OCEAN UNIV
Filing Date
2026-03-23
Publication Date
2026-06-30

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Abstract

This invention discloses a fibrinolytic enzyme-producing Pseudomonas hygroscopicus originating from mangrove wetlands (… Fictibacillus rigui The strain QMS71 is deposited at the China General Microbiological Culture Collection Center (CGMCC) under accession number CGMCC No. 37018. Under suitable culture conditions, strain QMS71 can produce extracellular enzymes with fibrin-degrading activity. Its fermentation products exhibit significant fibrin degradation activity in vitro and demonstrate thrombolytic and anticoagulant activities in relevant in vitro functional evaluation models. This invention provides a well-identified fibrinolytic enzyme-producing microbial resource and its applications, which can be used for in vitro functional evaluation, model studies, and functional enzymology research related to fibrin degradation.
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