A sample head output device and detection equipment
By designing a sample dispensing head output device, the attitude of the sample dispensing head can be changed and it can be used only once. This solves the problem of cleaning the sampling needle, reduces the risk of cross-contamination, simplifies the instrument structure, and ensures the reliability of the test results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- AVE SCI & TECH CO LTD
- Filing Date
- 2024-12-30
- Publication Date
- 2026-06-30
Smart Images

Figure CN122307137A_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of testing equipment technology, and in particular to a sample dispensing head output device and testing equipment. Background Technology
[0002] Clinical laboratory testing involves a series of procedures that examine specimens such as bodily fluids, secretions, excretions, and shed tissues from patients using visual observation and physical, chemical, instrumental, or molecular biological methods. It emphasizes strict quality management measures throughout the entire testing process (pre-analysis, analysis, and post-analysis) to ensure the quality of testing, thereby providing valuable results for clinical practice and assisting in diagnostic screening and other tasks.
[0003] In existing technologies, the testing of samples such as urine, feces, and gynecological secretions is typically performed by fully automated testing instruments. These instruments are usually equipped with sampling needles that draw up the prepared sample solution and inject it into a testing carrier (counting cell, counting plate, slide, test card, etc.) before sending it to subsequent units for the corresponding tests. However, existing sampling needles require cleaning after each sample to prevent contamination; this requires dedicated cleaning tanks, pumps, valves, and piping, resulting in high maintenance costs and inconsistent cleaning effectiveness. Therefore, cross-contamination remains a persistent problem in the industry. Summary of the Invention
[0004] To address the aforementioned technical problems, the first objective of this invention is to provide a sample dispensing head output device; the second objective is to provide a detection device. The sample dispensing head output device and detection device provided by this invention can achieve sample dispensing head posture conversion, coordinating with the posture of the sample dispensing head used in subsequent structures, thus facilitating sample liquid aspiration. Furthermore, the disposable sample dispensing head can be directly discarded after use without cleaning, simplifying the instrument structure, reducing or avoiding cross-contamination, and ensuring the reliability of the detection results.
[0005] The technical solution provided by this invention is as follows: A sample dispensing head output device includes: a mounting component, an ejection mechanism, and a conveying mechanism. The mounting component is used to detachably mount the storage box, which has an opening, and multiple sample dispensing heads are stacked in parallel inside the storage box. When the storage box is mounted on the mounting component, the axial extension direction of the sample dispensing heads is a first direction. The ejection mechanism includes a pushing component that moves along a second direction to push the sample dispensing head from the opening to the conveying mechanism; The conveying mechanism guides the sample dispensing head to the loading position, and the axis of the sample dispensing head located at the loading position extends in the third direction; The first direction is perpendicular to the third direction.
[0006] Preferably, the pushing component is at least partially disposed below the opening; The conveying mechanism includes a conveying channel, the entrance of which is located on the moving path of the pushing component, and the conveying channel is at least partially located below the pushing component to receive the sample application head pushed by the pushing component.
[0007] Preferably, the outlet of the conveying channel is connected to the loading position; from the inlet to the outlet direction, the inner diameter of the conveying channel is reduced at least partially.
[0008] Preferably, the conveying channel is provided with a housing, and the housing is at least partially transparent.
[0009] Preferably, the first direction is perpendicular to or parallel to the second direction; The pushing component is provided with a pushing groove that cooperates with the sample dispensing head, and the extending direction of the pushing groove is parallel to the first direction.
[0010] Preferably, the first direction is perpendicular to the second direction; The pushing component is provided with a first pushing groove, the bottom of which is completely empty; or the bottom end of the first pushing groove has a base plate, and the length of the base plate is less than half the length of the sample feeding head.
[0011] Preferably, the first direction is parallel to the second direction; The pushing component is provided with a second pushing groove, the bottom of which is completely empty; or the second pushing groove is provided with a base plate, the length of which is less than half the length of the sample feeding head.
[0012] Preferably, the mounting component and / or ejection mechanism are provided with a disturbance mechanism for agitating the sample dispensing head at the opening.
[0013] Preferably, the disturbance mechanism provided in the pushing mechanism is specifically a disturbance protrusion provided on the upper surface of the pushing component, the disturbance protrusion extending at least partially into the opening.
[0014] Preferably, a temporary storage mechanism is also provided, which includes a temporary storage component and a switching power source. The temporary storage component has at least two temporary storage cavities, and the switching power source drives the temporary storage component to rotate, switching different temporary storage cavities to the loading position.
[0015] A testing device, comprising the sample dispensing head output device described in any of the above claims.
[0016] This application provides a sample dispensing head output device, including: a mounting component, a pushing mechanism, and a conveying mechanism. The mounting component is used to detachably mount a storage box, which has an opening. Multiple sample dispensing heads are stacked in parallel inside the storage box, and when the storage box is mounted on the mounting component, the axial extension direction of the sample dispensing heads is a first direction. When the opening is open, the sample dispensing heads inside the box will move towards the opening under the action of gravity and fall out from it. The pushing mechanism includes a pushing component that moves along a second direction to push the sample dispensing head from the opening to the conveying mechanism. The conveying mechanism guides the sample dispensing head to the loading position and changes the orientation of the sample dispensing head in the process, so that the axial extension direction of the sample dispensing head located at the loading position is a third direction. The first direction and the third direction are perpendicular to each other, thereby realizing the conversion of the sample dispensing head posture, which is coordinated with the posture of the sample dispensing head used in subsequent structures, providing convenience for the sample dispensing head to draw sample liquid. The instrument uses a disposable dispensing tip to draw sample liquid from a sample container for testing. After use, the dispensing tip is discarded and a new dispensing tip is used to draw the next sample liquid. This eliminates the need for cleaning, simplifies the instrument structure, reduces or avoids cross-contamination, and ensures the reliability of the test results.
[0017] This application also provides a detection device using the above-mentioned sample head output device, which uses an automatically output disposable sample head to draw up sample liquid and apply it to a carrier for detection. Attached Figure Description
[0018] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of the sample dispensing head output device in an embodiment of the present invention; Figure 2 This is a schematic diagram of the sample dispensing head output device in an embodiment of the present invention (not placed in the storage box); Figure 3 This is a schematic diagram of the sample dispensing head output device in an embodiment of the present invention (mounting components are not shown); Figure 4 This is a schematic diagram of the sample dispensing head output device from another angle in an embodiment of the present invention (mounting components are not shown). Figure 5 This is a schematic diagram of the sample dispensing head output device in an embodiment of the present invention (perspective view of the storage box); Figure 6 This is a side view of the sample dispensing head output device in an embodiment of the present invention (the pushing component is provided with a first pushing groove); Figure 7 This is a side view of the sample dispensing head output device in an embodiment of the present invention (the pushing component is provided with a second pushing groove); Figure 8 This is a schematic diagram of the working process of the sample dispensing head output device in an embodiment of the present invention. Figure 1 (The sample dispensing head falls into the first push slot); Figure 9 This is a schematic diagram of the working process of the sample dispensing head output device in an embodiment of the present invention. Figure 2 (The sample dispensing head is pushed to the conveying mechanism by the pushing component); Figure 10 This is a schematic diagram of the working process of the sample dispensing head output device in an embodiment of the present invention. Figure 3 (The sample dispensing head is guided by the curved guide wall to change from a horizontal position to an vertical position during its descent in the conveyor channel.) Figure 11 This is a schematic diagram of a pushing component in an embodiment of the present invention (with a first pushing slot). Figure 12 This is a schematic diagram of another structure of the pushing component in an embodiment of the present invention (with a second pushing groove). Figure 13 This is a schematic diagram of the structure of a storage box that can be used in an embodiment of the present invention; Reference numerals: 1-Mounting component; 2-Ejection mechanism; 21-Support plate; 22-Pushing component; 221-First pushing groove; 222-Second pushing groove; 23-Pushing power source; 24-Pushing transmission component; 3-Transfer mechanism; 31-Transfer channel; 311-Arc-shaped guide wall; 32-Housing shell; 33-Guide component; 4-Disturbance mechanism; 41-Disturbance protrusion; 5-Temporary storage mechanism; 51-Temporary storage component; 511-Temporary storage cavity; 52-Switching power source; a-Storage box; a1-Opening; a2-Avoidance groove; b-Sample dispensing head. Detailed Implementation
[0020] To enable those skilled in the art to better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.
[0021] It should be noted that when a component is referred to as being "fixed to" or "set on" another component, it can be directly on or indirectly set on the other component; when a component is referred to as being "connected to" another component, it can be directly connected to or indirectly connected to the other component.
[0022] It should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.
[0023] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, "a plurality of" or "several" means two or more, unless otherwise explicitly specified.
[0024] It should be noted that the structures, proportions, sizes, etc., shown in the accompanying drawings of this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed in the specification, and are not intended to limit the conditions under which this application can be implemented. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportions, or adjustments to the size should still fall within the scope of the technical content disclosed in this application, provided that they do not affect the effects and purposes that this application can produce.
[0025] As shown in the figure, an embodiment of the present invention provides a sample dispensing head output device, including: a mounting component 1, an ejection mechanism 2, and a conveying mechanism 3. The mounting component 1 is used to detachably mount the storage box a. The storage box a has an opening a1. Multiple sample application heads b are stacked in parallel inside the storage box a. When the storage box a is mounted on the mounting component 1, the axial extension direction of the sample application heads b is the first direction. The ejection mechanism 2 includes a pushing component 22, which moves along a second direction to push the sample head b from the opening a1 to the conveying mechanism 3. The conveying mechanism 3 guides the sample dispensing head b to the loading position, and the axis of the sample dispensing head b located at the loading position extends in the third direction; The first direction is perpendicular to the third direction.
[0026] This application provides a sample dispensing head output device, including: a mounting component 1, a dispensing mechanism 2, and a conveying mechanism 3. The mounting component 1 is used to detachably mount a storage box a. The storage box a has an opening a1. Multiple sample dispensing heads b are stacked in parallel inside the storage box a. When the storage box a is mounted on the mounting component 1, the axial extension direction of the sample dispensing heads b is a first direction. When the opening a1 is open, the sample dispensing heads b inside the box will move towards the opening a1 under the action of gravity and fall out from it. The dispensing mechanism 2 includes a pushing component 22. The pushing component 22 moves along a second direction to push the sample dispensing heads b from the opening a1 along the second direction to the conveying mechanism 3. The conveying mechanism 3 guides the sample dispensing heads b to the loading position and changes the orientation of the sample dispensing heads b in the process, so that the axial extension direction of the sample dispensing heads b located at the loading position is a third direction. The first direction and the third direction are perpendicular to each other, thereby realizing the conversion of the posture of the sample dispensing heads b, which is coordinated with the posture of the sample dispensing heads b used in subsequent structures, and provides convenience for the sample dispensing heads b to draw sample liquid. The sample solution in a sample container is drawn using a disposable dispensing tip b. After use, the dispensing tip b is discarded and a new dispensing tip b is used to draw the next sample solution. This eliminates the need for cleaning, simplifies the instrument structure, reduces or avoids cross-contamination, and ensures the reliability of the test results.
[0027] The sample dispensing head b can have multiple outputs or a single output. From the perspective of guidance and ease of use, it is preferred that the sample dispensing head b outputs a single output from the opening a1. The single output of the sample dispensing head b can be achieved by opening a1 being sized so that only one sample dispensing head b can pass through; or the size of opening a1 can be larger than the size of one sample dispensing head b, but during the back-and-forth movement of the ejection mechanism 2 below opening a1, a portion of its structure closes a portion of the area of opening a1, so that only one sample dispensing head b can fall onto the path pushed by the ejection mechanism 2 at a time.
[0028] Preferably, the pushing component 22 is at least partially disposed below the opening a1; The conveying mechanism 3 includes a conveying channel 31, the entrance of which is located on the moving path of the pushing component 22, and the conveying channel 31 is at least partially located below the pushing component 22 to receive the sample application head b pushed by the pushing component 22.
[0029] Preferably, the pushing component 22 is at least partially disposed below the opening a1, so that the sample application head b is continuously pushed from the opening a1 along the second direction by the reciprocating movement of the pushing component 22; the conveying mechanism 3 includes a conveying channel 31, the entrance of the conveying channel 31 is located on the moving path of the pushing component 22, and the conveying channel 31 is at least partially located below the pushing component 22, so as to receive the sample application head b pushed by the pushing component 22 and ensure that the sample application head b enters the conveying channel 31.
[0030] The conveying channel 31 is located at least partially below the pushing member 22, which allows the sample head b to fall within the conveying channel 31 due to its own gravity; more preferably, the entire conveying channel 31 is located below the plane in which the pushing member 22 moves.
[0031] The entrance to the conveying channel 31 can be located at any point along the moving path of the pushing component 22 to receive the sample dispensing head b pushed by the pushing component 22. The entrance to the conveying channel 31 can be located at either end of the moving path of the pushing component 22 or at any point along the way. More preferably, the entrance to the conveying channel 31 is located at one end of the moving path of the pushing component 22, and the farthest distance that the pushing component 22 pushes the sample dispensing head b is exactly matched with the entrance position of the conventional channel 31. This can increase the distance between the entrance of the conveying channel 31 and the opening a1 of the storage box a, and the pushing frequency of the sample dispensing head b can be controlled by the path length and the moving speed of the pushing component 22.
[0032] Preferably, the outlet of the conveying channel 31 is connected to the loading position; from the inlet to the outlet direction, the inner diameter of the conveying channel 31 is reduced in at least part.
[0033] The entrance of the conveying channel 31 is located on the moving path of the pushing component 22, receiving the sample application head b, while the exit connects to the loading position. From the entrance to the exit, at least part of the inner diameter of the conveying channel 31 decreases. Therefore, as the sample application head b moves within the conveying channel 31, it is affected by the reduced inner diameter and changes its posture, ultimately reaching the loading position with its axial extension direction in a third direction. By utilizing the guidance of the change in the inner diameter of the conveying channel 31, the sample application head b naturally changes direction during its descent within the conveying channel 31, changing from axial extension along the first direction to axial extension along a third direction. This eliminates the need for complex posture transformation mechanisms and external power, achieving posture adjustment of the sample application head b simply, durablely, and reliably.
[0034] The portion of the reduced inner diameter of the conveying channel 31 only needs to be located between the inlet and outlet; its specific location does not affect the adjustment of the orientation of the sample feeding head b. Furthermore, after the orientation adjustment, increasing the inner diameter of the conveying channel 31 will not adversely affect the orientation of the sample feeding head b.
[0035] Preferably, at least one sidewall of the conveying channel 31 is an arc-shaped guide wall 311 to achieve a change in inner diameter. More preferably, the arc-shaped guide wall 311 gradually approaches the opposite sidewall from the inlet to the outlet of the conveying channel 31 until the inner diameter is minimized, causing the sample dispensing head b to rotate axially to a third direction. The conveying channel 31 can be provided with a complete annular arc-shaped guide wall 311, with the inner diameter decreasing from the inlet to the outlet of the conveying channel 31; alternatively, one or two of the four sidewalls can be set as arc-shaped, both of which can guide the sample dispensing head b.
[0036] Preferably, the conveying channel 31 is provided with a housing 32, and the housing 32 is at least partially transparent.
[0037] Preferably, the conveying channel 31 is provided with a housing 32, which is at least partially transparent, so that it is possible to observe whether the sample head b is stuck inside the conveying channel 31, so as to deal with it in time.
[0038] The transmission channel 31 is a cavity enclosed by a solid structure, which can be formed by, for example, a guide 33 cooperating with the housing 32.
[0039] Preferably, the first direction is perpendicular to or parallel to the second direction; The pushing component 22 is provided with a pushing groove that cooperates with the sample application head b, and the extending direction of the pushing groove is parallel to the first direction.
[0040] Preferably, the first direction (the axial extension direction of the sample dispensing head b when it is in the storage box a) and the second direction (the direction in which the pushing component 22 pushes the sample dispensing head b) are perpendicular or parallel to each other. At the same time, a pushing groove that cooperates with the sample dispensing head b is provided in the pushing component 22. The extension direction of the pushing groove is parallel to the first direction. So, regardless of whether the first direction is parallel or perpendicular to the second direction, the pushing groove can limit the sample dispensing head b and drive it to move together with the pushing component 22.
[0041] When the pushing component 22 is also provided with a pushing groove, as the pushing component 22 moves, the relative position of the pushing groove and the opening a1 also moves. When they reach the matching position, the sample head b can fall into the pushing groove by gravity.
[0042] More preferably, the portion of the pusher component 22 without the pusher groove acts as a cover for the opening a1, sealing the opening a1 to prevent the sample head b from falling out randomly. Only when the pusher groove is aligned with the opening a1 will the sample head b fall into the pusher groove, thereby achieving the effect of orderly and stable output of the sample head b.
[0043] Specifically, firstly, the sample dispensing head b is pushed by the ejection mechanism 2 with its axial extension direction as the first direction. By controlling the posture of the sample dispensing head b within the storage box a, and the position and size of the opening a1 of the storage box a, in conjunction with the setting of the mounting component 1, the sample dispensing head b can be pushed out of the opening a1 by the ejection mechanism 2 with its axial extension direction as the first direction. For example, if the opening a1 is located at the top corner of the storage box a, and the sample dispensing heads b inside the storage box a are neatly arranged according to the shape of the opening a1, and the mounting component 1 is equipped with a limiting plate or limiting rod that matches the shape of the storage box a, the storage box a can be stably placed on the mounting component 1 with the opening a1 facing downwards, thus achieving the above effect.
[0044] Then, the sample feeding head b is pushed by the ejection mechanism 2 along the second direction until it enters the entrance of the conveying channel 31 located on the moving path of the pusher 22. During its movement in the conveying channel 31, it is affected by the channel and changes direction. When it reaches the transfer position, the extension direction of the axis of the sample feeding head b becomes the third direction.
[0045] The preferred orientation of the sample dispensing head b is when its axis is parallel to the horizontal plane in the first direction (also known as the orientation of the sample dispensing head b lying flat); the preferred orientation in the third direction is when its axis is perpendicular to the horizontal plane (also known as the orientation of the sample dispensing head b standing upright). If the first direction is perpendicular to or parallel to the second direction, then the second direction pushed by the pushing component 22 is also located in the horizontal plane, but at a different angle from the direction of extension of the axis of the sample dispensing head b.
[0046] More preferably, the distance between the two adjacent side walls of the conveying channel 31 and the arc-shaped guide wall 311 is greater than the diameter of a single sample head b but less than the length of the sample head b. In this way, even if the sample head b is tilted to the sides during the transformation process guided by the arc-shaped guide wall 311, it will not be able to completely become flat due to the limitation of the two side walls, thus ensuring that the sample head b is finally discharged from the outlet of the conveying channel 31 in an upright posture.
[0047] The reciprocating movement of the pushing mechanism 22 can be achieved using power sources and transmission components known in the art. For example, the following structure can be used: a support plate 21, a pushing power source 23, and a pushing transmission component 24. The support plate 21 is located below the mounting component 1, and the pushing component 22 is slidably mounted on the support plate 21. The pushing transmission component 24 is powered to connect the pushing power source 23 and the pushing component 22, thereby transmitting the power of the pushing power source 23 to the pushing component 22. By switching the power output direction, the pushing component 22 can be moved back and forth.
[0048] The pushing component 22 is slidably mounted on the support plate 21, which can be achieved using methods known in the art such as slide rails and sliders. The pushing transmission component 24 transmits power, which can also be achieved using methods known in the art such as transmission belts, transmission pulleys, and transmission gears.
[0049] Preferably, the first direction is perpendicular to the second direction; The pushing component 22 is provided with a first pushing groove 221, the bottom of which is completely empty; or the bottom end of the first pushing groove 221 has a base plate, and the length of the base plate is less than half the length of the sample feeding head b.
[0050] When the first direction is perpendicular to the second direction, the pushing component 22 is provided with a first pushing groove 221. At this time, the axis of the first pushing groove 221 is parallel to the first direction, which is also perpendicular to the second direction. When the sample head b moves within the first pushing groove 221, it is pushed from the rear and limited from the front by the two side walls of the first pushing groove 221, keeping the movement of the sample head b within the control range. The first pushing groove 221 requires that its bottom structure is completely empty in the first type. When the push reaches the target position, the sample head b naturally falls from the bottom empty into the conveying channel 31. The second type of structure has a bottom plate at one end (the other end is empty), but at this time, the length of the bottom plate along the axis of the sample head b is less than half the length of the sample head b (e.g., Figure 11 As shown), the sample feeding head b, under its own weight, will first fall off at one end, and then the entire head will fall from the base plate into the conveying channel 31 (as shown). Figure 10 (As shown).
[0051] Preferably, the first direction is parallel to the second direction; The pushing component 22 is provided with a second pushing groove 222, the bottom of which is completely empty; or the second pushing groove 222 is provided with a base plate, and the length of the base plate is less than half the length of the sample feeding head b.
[0052] When the axial direction of the sample feeding head b is parallel to the moving direction of the pushing component 22, the pushing component 22 is provided with a second pushing groove 222. The axial direction of the second pushing groove 222 is parallel to both the first and second directions. Based on this, the second pushing groove 22 can have three structures: The first is that the bottom of the second pushing groove 222 is completely empty, similar to the first pushing groove 222. When it reaches the target position, the sample feeding head b falls from the empty bottom into the conveying channel 31. Or the second structure: the second pushing groove 222 is provided with a bottom plate, and the length of the bottom plate is less than half the length of the sample feeding head b. Then, during the pushing process, after the sample feeding head b reaches the target position, under its own gravity, one end of the sample feeding head b falls first, and then the whole thing falls from the bottom plate into the conveying channel 31 (e.g., ...). Figure 7 (As shown). The length of the base plate can be shorter than the entire pushing component 22, or it can be the same length as the pushing component 22 (e.g., ...). Figure 12 As shown in the figure, ensure that the length of the base plate is less than half the length of the sample feeding head b.
[0053] Preferably, the mounting component 1 and / or the ejection mechanism 2 are provided with a disturbance mechanism 4 for disturbing the sample feeding head b of the opening a1.
[0054] Preferably, the mounting component 1 and / or the ejection mechanism 2 are also provided with a disturbance mechanism 4, which is used to disturb the sample dispensing head b at the opening a1 to avoid the sample dispensing head b being blocked at the opening a1 and thus preventing it from being able to output individually, and to ensure that the output process of the sample dispensing head b proceeds smoothly.
[0055] In this application, the disturbance of the sample dispensing head b by the disturbance mechanism 4 refers to lifting and vibrating it, causing the sample dispensing head b in contact with the disturbance mechanism 4 and the sample dispensing heads b nearby to move, thereby loosening the stacked sample dispensing heads b and avoiding blockage.
[0056] Preferably, the disturbance mechanism 4 provided in the pushing mechanism 2 is specifically a disturbance protrusion 41 provided on the upper surface of the pushing component 22, and the disturbance protrusion 41 extends at least partially into the opening a1.
[0057] As one implementation of the disturbance mechanism 4, the disturbance mechanism 4 preferably provided in the push mechanism 2 is a disturbance protrusion 41 provided on the upper surface of the push member 22, and the disturbance protrusion 41 extends at least partially into the opening a1. The disturbance protrusion 41 is provided on the upper surface of the push member 22, and its height is naturally higher than the height of the push member 22. By controlling the size of each component and the distance between them, the disturbance protrusion 41 can be extended into the opening a1 to push the sample head b upward, so that the opening a1 and the sample heads b arranged nearby are loosened, thereby achieving the effect of disturbing the sample head b and preventing it from blocking the opening a1.
[0058] The disturbance protrusion 41 extends into the opening a1. This can be achieved by creating a clearance groove a2 corresponding to the protrusion in the storage box a. The disturbance protrusion 41 moves into the clearance groove a2 as the pushing component 22 moves, lifting the sample dispensing head b stacked in the opening a1 to achieve disturbance. Alternatively, the disturbance protrusion 41 can also extend into the opening a1 through other matching structures.
[0059] Preferably, the height of the disturbance ridge 41 gradually increases near the end of the conveying mechanism 3; and / or, The top surface of the disturbance ridge 41 is wavy.
[0060] More preferably, the height of the end of the disturbance protrusion 41 near the conveying mechanism 3 gradually increases. During the process of the pushing component 22 moving towards the conveying mechanism 3 (i.e. the process of pushing out the sample head b), the protrusion 41 gradually lifts the sample head b by using the part with gradually increasing height, thereby reducing bumps and impacts during the disturbance process and extending the service life of each component.
[0061] Alternatively, the top surface of the disturbance ridge 41 can be wavy. During the movement of the disturbance ridge 41, the wavy top surface will lift the storage box a to different heights, thereby enabling the storage box a to move up and down and also disturbing the sample dispensing head b inside.
[0062] As a second implementation of the disturbance mechanism 4, the disturbance mechanism 4 provided on the mounting component 1 can be a vibration assembly; the vibration assembly includes a vibration power source and a vibration head that reciprocates to strike the mounting component 1 or the storage box a under its drive, thereby achieving vibration of the storage box a through striking.
[0063] Preferably, a temporary storage mechanism 5 is also provided, which includes a temporary storage component 51 and a switching power source 52. The temporary storage component 51 has at least two temporary storage cavities 511. The switching power source 52 drives the temporary storage component 51 to rotate and switches different temporary storage cavities 511 to the loading position.
[0064] More preferably, the sample dispensing head output device provided in this application is further provided with a temporary storage mechanism 5. The temporary storage mechanism 5 includes a temporary storage component 51 and a switching power source 52. The temporary storage component 51 has at least two temporary storage cavities 511. The switching power source 52 drives the temporary storage component 51 to rotate, switching different temporary storage cavities 511 to the loading position and receiving the sample dispensing head b whose axial direction is already third-party.
[0065] The diameter of the temporary storage cavity 511 can be slightly larger than the diameter of the sample dispensing head b, so that the sample dispensing head b can be in an upright position during temporary storage. The temporary storage component 51 can also be provided with a retrieval position that cooperates with the downstream mechanism. The temporary storage cavity 511, which has received the sample dispensing head b, is rotated to the retrieval position in sequence for retrieval. By coordinating with the working frequency of the ejection mechanism 2, the rhythm of the sample dispensing head b from output to retrieval can be made to meet the detection requirements.
[0066] The temporary storage component 51 is provided with at least two temporary storage cavities 511, one of which is empty when receiving the sample head b and the other is full when supplying the sample head b; more than one, such as 4-10, temporary storage cavities 511 can also be provided as needed.
[0067] A testing device, comprising the sample dispensing head output device described in any of the above claims.
[0068] This application also provides a detection device using the above-mentioned sample head output device, which uses an automatically output disposable sample head b to draw up sample liquid and apply it to a carrier for detection.
[0069] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims
1. A sample dispensing head output device, characterized in that, include: The installation components (1), the ejection mechanism (2), and the conveying mechanism (3) are installed. The mounting component (1) is used to detachably mount the storage box (a). The storage box (a) has an opening (a1). Multiple sample application heads (b) are stacked in parallel inside the storage box (a). When the storage box (a) is mounted on the mounting component (1), the axial extension direction of the sample application head (b) is the first direction. The ejection mechanism (2) includes a pusher (22) that moves in a second direction and pushes the sample head (b) from the opening (a1) to the conveying mechanism (3). The conveying mechanism (3) guides the sample dispensing head (b) to the loading position, and the axis of the sample dispensing head (b) located at the loading position extends in the third direction; The first direction is perpendicular to the third direction.
2. The sample dispensing head output device according to claim 1, characterized in that, The pushing component (22) is at least partially disposed below the opening (a1); The conveying mechanism (3) includes a conveying channel (31), the entrance of which is located on the moving path of the pushing component (22), and the conveying channel (31) is at least partially located below the pushing component (22) to receive the sample head (b) pushed by the pushing component (22).
3. The sample dispensing head output device according to claim 2, characterized in that, The outlet of the conveying channel (31) is connected to the loading position; the inner diameter of the conveying channel (31) is reduced at least partially from the inlet to the outlet direction.
4. The sample dispensing head output device according to claim 2, characterized in that, The transmission channel (31) is provided with a housing (32) outside, and the housing (32) is at least partially transparent.
5. The sample dispensing head output device according to any one of claims 1-4, characterized in that, The first direction is perpendicular to or parallel to the second direction; The pushing component (22) is provided with a pushing groove that cooperates with the sample application head (b), and the extending direction of the pushing groove is parallel to the first direction.
6. The sample dispensing head output device according to claim 5, characterized in that, The first direction is perpendicular to the second direction; The pushing component (22) is provided with a first pushing groove (221), the bottom of the first pushing groove (221) is completely empty; or the bottom end of the first pushing groove (221) has a base plate, and the length of the base plate is less than half the length of the sample feeding head (b).
7. The sample dispensing head output device according to claim 5, characterized in that, The first direction is parallel to the second direction; The pushing component (22) is provided with a second pushing groove (222), the bottom of which is completely empty; or the second pushing groove (222) is provided with a base plate, and the length of the base plate is less than half the length of the sample feeding head (b).
8. The sample dispensing head output device according to any one of claims 1-4 and 6-7, characterized in that, The mounting component (1) and / or ejection mechanism (2) are provided with a disturbance mechanism (4) for agitating the sample feeding head (b) of the opening (a1).
9. The sample dispensing head output device according to claim 8, characterized in that, The disturbance mechanism (4) provided in the push mechanism (2) is specifically a disturbance protrusion (41) provided on the upper surface of the push member (22), the disturbance protrusion (41) extending at least partially into the opening (a1).
10. The sample dispensing head output device according to any one of claims 1-4, 6-7, and 9, characterized in that, A temporary storage mechanism (5) is also provided, which includes a temporary storage component (51) and a switching power source (52). The temporary storage component (51) has at least two temporary storage cavities (511). The switching power source (52) drives the temporary storage component (51) to rotate and switches different temporary storage cavities (511) to the loading position.
11. A testing device, characterized in that, The sample dispensing head output device includes any one of claims 1-10.