Use of n-acetylneuraminic acid in promoting growth of gut bacteria
By adding 0.1%-1.0% Neu5Ac to the composition, the unclear relationship between Neu5Ac and Bifidobacterium growth was resolved, resulting in a significant reduction in the growth lag phase and an improvement in Bifidobacterium growth efficiency, making it suitable for various product fields.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHILDRENS HOSPITAL OF FUDAN UNIV
- Filing Date
- 2026-05-08
- Publication Date
- 2026-07-17
AI Technical Summary
In existing studies, the relationship between Neu5Ac and the growth of Bifidobacteria has not been fully explored, making it difficult to directly influence the growth of Bifidobacteria using Neu5Ac, especially when it is not dependent on their metabolic capacity.
The addition of N-acetylneuraminic acid (Neu5Ac) to the composition at a weight-volume percentage of 0.1%-1.0% promotes the growth of intestinal bacteria and/or shortens the growth retardation period. It is suitable for culture media, probiotic preparations, infant formula, functional foods and pet nutritional supplements.
It significantly shortens the growth lag phase of Bifidobacteria, accelerates their entry into the logarithmic growth phase, increases the maximum biomass of Bifidobacteria, and promotes their growth independent of the strain's Neu5Ac metabolic capacity, which is universal.
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