Hermetia illucens extract, its extraction method and use in the prevention and treatment of tumors in companion animals

By preparing black soldier fly extract, a technological gap in the prevention and treatment of pet tumors has been filled, achieving effective treatment of tumors in companion animals, especially the inhibitory effect on tumor cells in dogs and cats.

CN122398864APending Publication Date: 2026-07-17SUN YAT SEN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SUN YAT SEN UNIV
Filing Date
2026-06-12
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

There is a lack of safe, effective, economical, and gentle methods for the prevention and treatment of tumors in pets in the current technology, and there are few reports on the application of black soldier flies in the field of anti-tumor treatment.

Method used

A method for preparing black soldier fly extract, including water extraction, non-polar extraction, and column chromatography, was used to obtain black soldier fly extract for the preparation of drugs for treating tumors in companion animals.

Benefits of technology

Black soldier fly extract has significant therapeutic effects on companion animal tumors, especially showing good inhibitory activity against DH82 canine malignant cancer cells and CRFK(T) feline kidney cell-induced tumor cells, and has no side effects on normal cells.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明属于生物医药技术领域,具体涉及黑水虻提取物及其提取方法和在防治肿瘤中的应用。本发明通过黑水虻虫粉进行极性成分的提取,得到的黑水虻提取物对伴侣动物肿瘤具有较好的治疗效果,对DH82狗肾恶性组织细胞增生症细胞、CRFK(T)猫肾细胞诱导成瘤细胞的增殖抑制活性,在同等质量浓度下显著优于未经分离的黑水虻虫粉。在细胞迁移划线实验中,黑水虻提取物对DH82狗肾恶性组织细胞增生症细胞具有很强的迁移抑制作用。
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