Preparation method of ganoderma lucidum polysaccharide and triterpene

By employing a phased pulverization and multiple alcohol extraction methods, the problem of low extraction rates of polysaccharides and triterpenoids from Ganoderma lucidum fruiting bodies was solved, resulting in a significant improvement in the extraction rates of Ganoderma lucidum polysaccharides and triterpenoids.

CN122398872APending Publication Date: 2026-07-17ZHEJIANG MEDICAL COLLEGE

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ZHEJIANG MEDICAL COLLEGE
Filing Date
2026-04-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing technologies, the extraction rates of Ganoderma lucidum polysaccharides and triterpenoids from Ganoderma lucidum fruiting bodies are low and difficult to further improve.

Method used

A staged pulverization and multiple ethanol extraction method was adopted. By processing Ganoderma lucidum fruiting bodies with different pulverization particle sizes, ethanol concentrations, temperatures, times, and centrifugation, Ganoderma lucidum polysaccharides and triterpenes were gradually extracted.

Benefits of technology

It significantly improved the extraction rates of Ganoderma lucidum polysaccharides and triterpenes, reaching 6.68% and 7.01% respectively, which is superior to traditional methods.

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Abstract

本发明提供了一种灵芝多糖和三萜的制备方法,属于医药制备技术领域。本发明提供的灵芝多糖和三萜的制备方法,包括如下步骤:(1)灵芝子实体粉碎后进行醇提,得到一次滤液和一次滤渣;(2)一次滤渣经烘干、粉碎后进行醇提,得到二次滤液和二次滤渣;(3)二次滤渣经烘干、粉碎后进行醇提,得到三次滤液和三次滤渣;(4)合并一次滤液、二次滤液和三次滤液,得到提取液,所述提取液干燥后得到灵芝多糖和三萜提取物。本发明提供的灵芝多糖和三萜的制备方法,分三个提取阶段设置不同的粉碎粒度分别进行提取,本发明对灵芝多糖的平均提取率为6.68%,三萜平均提取率为7.01%,说明本发明能够提高灵芝多糖和三萜的得率。
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