Echinocandin compounds, pharmaceutical compositions thereof, and uses thereof
By developing echinocandins, which have good stability, excellent antibacterial activity, long half-life, and good water solubility, the problem of the single structure of existing antifungal drugs has been solved, resulting in more efficient antifungal treatment and better patient compliance.
CN122404501APending Publication Date: 2026-07-17SHANGHAI INST OF PHARMA IND CO LTD +1
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHANGHAI INST OF PHARMA IND CO LTD
- Filing Date
- 2025-09-23
- Publication Date
- 2026-07-17
AI Technical Summary
Technical Problem
Existing antifungal drugs have relatively simple structures, leading to serious drug resistance problems, short half-lives, significant side effects, and poor patient compliance.
Method used
To develop a novel echinocandin compound with good stability, excellent antibacterial activity, long half-life, good water solubility, and easy absorption. The specific structure consists of compounds of formula I and formula II and their pharmaceutically acceptable salts.
Benefits of technology
It improves the stability and absorption of antifungal drugs, prolongs the half-life, reduces the frequency of administration, reduces side effects, and improves patient compliance.
✦ Generated by Eureka AI based on patent content.
Smart Images
Figure CN122404501A_ABST
Abstract
本发明公开一种棘白菌素类化合物、其药物组合物和应用。本发明具体公开一种式I化合物或其药学上可接受的盐，其具有以下一种或多种优势：稳定性好、抗菌活性优异、半衰期长、水溶性好、易于吸收。
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