Application of rice phlomis leaf phytoplasma outer membrane protein imp and alpha4 domain thereof in inhibition of rice stripe virus
By introducing the ROLP outer membrane protein Imp and its α4 domain into rice to interfere with RSMV virus particle assembly, transgenic rice was constructed, solving the problem of rice stripe mosaic virus control and achieving a highly efficient virus inhibition effect and an environmentally friendly resistance strategy.
CN122405720APending Publication Date: 2026-07-17FUJIAN AGRI & FORESTRY UNIV
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- FUJIAN AGRI & FORESTRY UNIV
- Filing Date
- 2026-06-05
- Publication Date
- 2026-07-17
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Abstract
本发明公开了水稻橙叶病植原体ROLP外膜蛋白Imp在抗水稻条纹花叶病中的应用。本发明将水稻橙叶病植原体外膜蛋白Imp基因中的功能结构域Impα4基因导入水稻植株中,ROLP的外膜蛋白Imp能够直接结合RSMV的包膜糖蛋白G,并通过其第96–122位氨基酸区域干扰G蛋白与RSMV基质蛋白M之间的关键互作,从而破坏RSMV病毒粒子的正常组装,导致病毒粒子结构变形、稳定性下降,最终显著降低RSMV的侵染能力。
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