A method for determining ncin-capped rna and m7g-capped rna contained in a sample
By employing sample processing and linker ligation methods, the accuracy of determining the NCIN and m7G capping ratios in eukaryotic RNA samples was resolved, enabling efficient identification of RNA capping types.
CN122445765APending Publication Date: 2026-07-24SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI
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Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHANGHAI INST OF ORGANIC CHEM CHINESE ACAD OF SCI
- Filing Date
- 2025-01-24
- Publication Date
- 2026-07-24
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Figure CN122445765A_ABST
Abstract
The present disclosure discloses a method for determining NCIN-capped RNA and m7G-capped RNA contained in a sample. The determination method can easily and accurately detect the amount of NCIN-capped RNA and m7G-capped RNA in mRNA of any eukaryote, and the proportion of NCIN-capped RNA and m7G-capped RNA relative to all capped RNA, which helps further research based on the RNA capping condition of the sample.
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