Sterile isolator with ventilation filtration function

Abstract

The application discloses a sterile isolator with a ventilation filtering function, relates to the technical field of sterile isolators, and comprises an isolator body, a ventilation box fixedly installed at the middle position of the surface of the isolator body, a box door installed at the position of the surface of the isolator body, perspective glass fixedly installed at the position of the surface of the box door, rubber gloves fixedly installed at the surface of the perspective glass and a transmission frame installed at the inner position of the isolator body. The isolator body is reasonable in structure, the object inside the isolator body can be fixed through the cooperation of the sliding assembly and the limiting assembly, sterilization and disinfection can be performed on the inside of the isolator body through the ventilation assembly, the inside of the isolator body is isolated from the outside air through the rotation of the air collecting plate, and the pollution caused by the entry of the outside air into the inside of the isolator body is avoided.

Description

Technical Field

[0001] This invention relates to the field of aseptic isolators, and in particular to an aseptic isolator with ventilation and filtration functions. Background Technology

[0002] In the field of sterile testing of pharmaceuticals and biological products, traditional open testing operations are susceptible to external contamination from the environment and personnel, affecting the accuracy and reliability of test results. Sterile isolators can create a closed and controllable sterile operating environment, effectively isolating external interference and providing a stable and compliant operating space for various sterile testing equipment. The combination of the two can significantly improve testing accuracy and meet the requirements of pharmaceutical quality control and related regulations.

[0003] Patent CN116999592A discloses a sterilization device for the return air duct of a sterile isolator, including an operating chamber with a return air duct outside the chamber. A hydrogen peroxide supply device is connected to the operating chamber via a hydrogen peroxide delivery channel. This application further includes: a first pipe with one end extending into the sterile isolator operating chamber; the other end of the first pipe is connected to the inlet of a first valve; the outlet of the first valve is connected to one end of a second pipe; and the other end of the second pipe extends into the return air duct. When the sterile isolator operating chamber is filled with hydrogen peroxide gas, this application uses the loop formed by the first pipe, the first valve, and the second pipe to input the hydrogen peroxide gas from the operating chamber into the return air duct, thereby achieving sterilization of the return air duct.

[0004] There are still some problems with the isolator during use. Existing equipment often uses simple placement or scattered fixing methods for items inside the chamber, lacking dedicated sliding and limiting structures. This makes them prone to displacement and shaking during operation, transfer, or sterilization, affecting operational accuracy and environmental stability. Meanwhile, conventional ventilation and disinfection systems suffer from uneven airflow distribution, low sterilization efficiency, and difficulty in quickly forming a stable, sealed space after exhaust, allowing external contaminants to easily seep in. This makes it impossible to maintain a high level of sterility and fails to meet the safety and reliability requirements of demanding aseptic operations. Summary of the Invention

[0005] The purpose of this application is to provide a sterile isolator with ventilation and filtration functions. It achieves the convenient fixation of objects inside the isolator body through the cooperation of sliding components and limiting components, the disinfection of the inside of the isolator body through ventilation components, and the isolation of the air inside the isolator body from the outside air through the rotation of the air collection plate, thus preventing the outside air from entering the isolator body and causing contamination.

[0006] To achieve the above objectives, this application provides the following technical solution: a sterile isolator with ventilation and filtration function, comprising an isolator body, a ventilation box fixedly installed at the center of the surface of the isolator body, a door installed on the surface of the isolator body, a transparent glass fixedly installed on the surface of the door, a rubber glove fixedly installed on the surface of the transparent glass, and a transfer rack installed inside the isolator body. It also includes a sliding component, a limiting component, and a ventilation component. The sliding component is disposed inside the isolator body for horizontal movement of the docking frame. The limiting component is disposed on the base plate for fixing the item. The ventilation component is disposed inside the ventilation box for drawing air from inside the isolator body.

[0007] Preferably, the sliding assembly includes a pair of rods fixedly installed inside the isolator body, with pulleys slidably connected to the pair of rods. The pulleys are rotatably connected to the docking frame. Through slots are provided on both sides of the docking frame, and a clamping plate is provided inside the docking frame. An arc-shaped groove is provided at the top of the clamping plate, and the inner wall of the arc-shaped groove is attached to the surface of the rod.

[0008] Preferably, side seats are fixedly connected to both sides of the clamping plate, one end of the side seat extends to the outside of the docking frame through the through groove, the side seat is slidably connected to the side rod, the bottom end of the side rod is fixedly connected to the shaft seat, the shaft seat is fixedly connected to the docking frame, the top end of the side rod is fixedly connected to the collar, and a spring is sleeved on the side rod, with both ends of the spring fixedly connected to the top surface of the side seat and the bottom surface of the collar, respectively.

[0009] Preferably, a crossbar is rotatably connected to the docking frame, a handle is fixedly connected to the middle of the crossbar, and cams are fixedly connected to both ends of the crossbar. The cams are attached to the bottom surface of the slide plate, and the slide plate is fixedly installed on the bottom surface of the clamping plate.

[0010] Preferably, the limiting component includes a base plate fixedly connected to the bottom surface of the docking frame, a first damping rod rotatably connected to the bottom end of the base plate, an arm plate fixedly connected to the first damping rod, a second damping rod rotatably connected to the other ends of the arm plates, and a bracket fixedly connected to the middle end of the second damping rod.

[0011] Preferably, the bracket has insert rods movably inserted at both ends, the bottom end of the insert rods is fixedly connected to a ring, and bolts are threaded onto the surface of the ring.

[0012] Preferably, the ventilation assembly includes a fan fixedly installed inside the ventilation box, a pipe fixedly connected to the bottom of the fan, a connecting pipe fixedly connected to the surface of the pipe in a transverse position, an air collecting plate rotatably connected to the connecting pipe, and the air collecting plate being located inside the isolator body.

[0013] Preferably, a first semicircular plate is fixedly connected to the opening of the connecting pipe, and a second semicircular plate is fixedly connected to the inner wall of the gas collecting plate, with the second semicircular plate attached to one end of the connecting pipe.

[0014] Preferably, a toothed ring is fixedly connected to the air collecting plate, a toothed plate meshes with the toothed ring, a sleeve is fixedly connected to the bottom end of the toothed plate, a threaded rod is threadedly connected to the sleeve, the bottom end of the threaded rod is rotatably connected to a horizontal plate, both ends of the horizontal plate are fixedly connected to the inner wall of the ventilation box, the bottom end of the threaded rod is fixedly connected to the output end of a servo motor, the servo motor is fixedly installed at the middle position of the bottom surface of the horizontal plate, and a filter plate is installed at the top position of the ventilation box.

[0015] In summary, the present invention has the following beneficial effects: 1. The present invention has a reasonable structure. When the position of the docking frame is moved, the handle is pulled down. The handle is fixedly connected to the middle position of the crossbar. Pulling the handle down causes the crossbar to rotate. The rotation of the crossbar drives the cam to rotate. Then the cam will move down by the elastic force of the spring. The slide plate is fixedly connected to the bottom position of the clamping plate. The movement of the slide plate causes the clamping plate to move down, so that the inner wall of the arc groove is separated from the surface of the rod. The pulley on the docking frame will move horizontally on the rod.

[0016] 2. In this invention, the ring is moved onto the object on the transmission frame. A rod is fixedly connected to the ring and is movably inserted into the bracket. The upward movement of the rod on the bracket facilitates the movement of the ring. The second damping rod rotates on the arm plate, and the first damping rod rotates on the base plate, which facilitates the adjustment of the ring's position. The rotating bolts facilitate the fixing of the object inside the ring.

[0017] 3. In this invention, the operation of the fan causes sterilizing air to enter the interior of the pipe through the filter plate. A connecting pipe is fixedly connected to the surface of the pipe, and a collecting plate is rotatably connected to the connecting pipe. The sterilizing air will sterilize the interior of the isolator body through the collecting plate. After sterilization, the operation of the fan causes the gas inside the isolator body to enter the interior of the connecting pipe through the collecting plate, and then be discharged through the ventilation box. After discharge, the operation of the servo motor causes the threaded rod to rotate, thereby facilitating the upward movement of the toothed plate on the sleeve to rotate the collecting plate on the toothed ring. Then, the second semicircular plate and the first semicircular plate seal the outlet of the connecting pipe, isolating the external air and preventing the external air from entering the interior of the isolator body and causing pollution. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of the isolator body; Figure 2 This is a side view of the isolator body in three-dimensional structure. Figure 3 This is a schematic diagram of the internal three-dimensional structure of the isolator body; Figure 4 This is a schematic diagram of the three-dimensional structure of the docking frame; Figure 5 This is a schematic diagram of the three-dimensional structure of the docking frame viewed from below. Figure 6 A schematic diagram of a partial cross-sectional three-dimensional structure of the isolator body; Figure 7 This is a schematic diagram of a partial cross-sectional three-dimensional structure of the ventilation box; Figure 8 for Figure 7 Enlarged structural diagram at point A in the middle.

[0020] In the diagram: 1. Isolator body; 101. Ventilation box; 102. Box door; 103. Transparent glass; 104. Rubber glove; 105. Transfer frame; 2. Rod; 201. Pulley; 202. Connecting frame; 203. Through groove; 204. Clamping plate; 205. Arc groove; 206. Side seat; 207. Side rod; 208. Shaft seat; 209. Collar; 210. Spring; 211. Crossbar; 212. Handle; 213. Cam; 214. Slide plate; 3. 301. Base plate; 302. First damping rod; 303. Arm plate; 304. Second damping rod; 305. Bracket; 306. Insert rod; 307. Ring; 308. Bolt; 4. Fan; 401. Pipe; 402. Connecting pipe; 403. Air collection plate; 404. First semicircular plate; 405. Second semicircular plate; 406. Gear ring; 407. Gear plate; 408. Sleeve; 409. Threaded rod; 410. Horizontal plate; 411. Servo motor; 412. Filter plate. Detailed Implementation

[0021] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0022] Example: Reference Figure 1 - Figure 8 The sterile isolator with ventilation and filtration function shown includes an isolator body 1, a ventilation box 101 fixedly installed at the center of the surface of the isolator body 1, a door 102 installed on the surface of the isolator body 1, a transparent glass 103 fixedly installed on the surface of the door 102, a rubber glove 104 fixedly installed on the surface of the transparent glass 103, and a transfer rack 105 installed inside the isolator body 1; it also includes a sliding component, a limiting component, and a ventilation component. The sliding component is disposed inside the isolator body 1 for horizontal movement of the docking rack 202, the limiting component is disposed on the base plate 3 for fixing the items, and the ventilation component is disposed inside the ventilation box 101 for extracting air from inside the isolator body 1.

[0023] Specifically, it should be noted that the top of the ventilation box 101 is connected to the ventilation pipe, and then both hands are inserted into the inside of the rubber gloves 104 to facilitate operation inside the isolator body 1. The fan 4 and the servo motor 411 are operated through wires and control unit. Their specific working principle is based on existing technology and will not be elaborated on here.

[0024] In one embodiment of this invention, the sliding assembly includes a pair of rods 2 fixedly installed inside the isolator body 1. A pulley 201 is slidably connected to the pair of rods 2, and the pulleys 201 are rotatably connected to a docking frame 202. Through slots 203 are provided on both sides of the docking frame 202. A clamping plate 204 is provided inside the docking frame 202, and an arc-shaped groove 205 is provided at the top of the clamping plate 204. The inner wall of the arc-shaped groove 205 fits against the surface of the rods 2. Side seats 206 are fixedly connected to both sides of the clamping plate 204. One end of the side seat 206 extends out of the docking frame 202 through the through slots 203, and the side seat 206 is slidably connected to... The bottom end of the side rod 207 is fixedly connected to the bearing seat 208, which is fixedly connected to the docking frame 202. The top end of the side rod 207 is fixedly connected to the collar 209. A spring 210 is sleeved on the side rod 207. The two ends of the spring 210 are fixedly connected to the top surface of the side seat 206 and the bottom surface of the collar 209, respectively. A crossbar 211 is rotatably connected to the docking frame 202. A handle 212 is fixedly connected to the middle end of the crossbar 211. Cams 213 are fixedly connected to both ends of the crossbar 211. The cams 213 are in contact with the bottom surface of the slide plate 214. The slide plate 214 is fixedly installed on the bottom surface of the clamping plate 204.

[0025] Specifically, when moving the position of the docking frame 202, the handle 212 is pulled downwards. The handle 212 is fixedly connected to the middle position of the crossbar 211. Pulling the handle 212 downwards causes the crossbar 211 to rotate. The rotation of the crossbar 211 drives the cam 213 to rotate. Then, the cam 213 moves downwards due to the elastic force of the spring 210. The slide plate 214 is fixedly connected to the bottom position of the clamping plate 204. The movement of the slide plate 214 causes the clamping plate 204 to move downwards, causing the inner wall of the arc groove 205 to detach from the surface of the rod body 2. The pulley 201 on the docking frame 202 moves horizontally on the rod body 2.

[0026] As one embodiment of this invention, the limiting component includes a base plate 3 fixedly connected to the bottom surface of the docking frame 202. A first damping rod 301 is rotatably connected to the bottom end of the base plate 3. An arm plate 302 is fixedly connected to the first damping rod 301. A second damping rod 303 is rotatably connected to the other end of the arm plate 302. A bracket 304 is fixedly connected to the middle end of the second damping rod 303. Insert rods 305 are movably inserted at both ends of the bracket 304. The bottom end of the insert rod 305 is fixedly connected to a ring 306. Bolts 307 are threadedly connected to the surface of the ring 306.

[0027] Specifically, the ring 306 is moved onto the object on the transmission frame 105. A rod 305 is fixedly connected to the ring 306 and is movably inserted into the bracket 304. The rod 305 moves upward on the bracket 304 to facilitate the movement of the ring 306. The second damping rod 303 rotates on the arm plate 302, and the first damping rod 301 rotates on the base plate 3 to facilitate the adjustment of the position of the ring 306. The object is fixed inside the ring 306 by rotating the bolt 307.

[0028] In one embodiment of this invention, the ventilation assembly includes a fan 4 fixedly installed inside the ventilation box 101. A pipe 401 is fixedly connected to the bottom of the fan 4. A connecting pipe 402 is fixedly connected laterally to the surface of the pipe 401. A collecting plate 403 is rotatably connected to the connecting pipe 402, located inside the isolator body 1. A first semicircular plate 404 is fixedly connected to the opening of the connecting pipe 402, and a second semicircular plate 405 is fixedly connected to the inner wall of the collecting plate 403. The second semicircular plate 405 is attached to one side of the connecting pipe 402. At the end position, a toothed ring 406 is fixedly connected to the air collecting plate 403, a toothed plate 407 meshes with the toothed ring 406, a sleeve 408 is fixedly connected to the bottom end of the toothed plate 407, a threaded rod 409 is threadedly connected to the sleeve 408, the bottom end of the threaded rod 409 is rotatably connected to the horizontal plate 410, both ends of the horizontal plate 410 are fixedly connected to the inner wall of the ventilation box 101, the bottom end of the threaded rod 409 is fixedly connected to the output end of the servo motor 411, the servo motor 411 is fixedly installed in the middle of the bottom surface of the horizontal plate 410, and a filter plate 412 is installed at the top of the ventilation box 101.

[0029] Specifically, the operation of the fan 4 causes sterilizing air to enter the interior of the pipe 401 through the filter plate 412. A connecting pipe 402 is fixedly connected to the surface of the pipe 401, and a collecting plate 403 is rotatably connected to the connecting pipe 402. The sterilizing air will sterilize the interior of the isolator body 1 through the collecting plate 403. After sterilization, the operation of the fan 4 causes the gas inside the isolator body 1 to enter the interior of the connecting pipe 402 through the collecting plate 403, and then be discharged through the ventilation box 101. After discharge, the operation of the servo motor 411 causes the threaded rod 409 to rotate, thereby facilitating the upward movement of the toothed plate 407 on the sleeve 408 to rotate the collecting plate 403 on the toothed ring 406. Then, the second semicircular plate 405 and the first semicircular plate 404 seal the outlet of the connecting pipe 402 to isolate the outside air and prevent the outside air from entering the interior of the isolator body 1 and causing pollution.

[0030] The working principle of this invention is as follows: When the position of the docking frame 202 is moved, the handle 212 is pulled downward. The handle 212 is fixedly connected to the middle position of the crossbar 211. The downward pulling of the handle 212 causes the crossbar 211 to rotate. The rotation of the crossbar 211 drives the cam 213 to rotate. Then the cam 213 will move downward by the elastic force of the spring 210. The slide plate 214 is fixedly connected to the bottom position of the clamping plate 204. The movement of the slide plate 214 causes the clamping plate 204 to move downward, so that the inner wall of the arc groove 205 is separated from the surface of the rod body 2. The pulley 201 on the docking frame 202 will move horizontally on the rod body 2.

[0031] The ring 306 is moved to the object on the transmission frame 105. A rod 305 is fixedly connected to the ring 306 and is movably inserted into the bracket 304. The rod 305 moves upward on the bracket 304 to facilitate the movement of the ring 306. The second damping rod 303 rotates on the arm plate 302, and the first damping rod 301 rotates on the base plate 3 to facilitate the adjustment of the position of the ring 306. The object is fixed inside the ring 306 by rotating the bolt 307.

[0032] The operation of the fan 4 causes sterilizing air to enter the interior of the pipe 401 through the filter plate 412. A connecting pipe 402 is fixedly connected to the surface of the pipe 401, and a collecting plate 403 is rotatably connected to the connecting pipe 402. The sterilizing air will sterilize the interior of the isolator body 1 through the collecting plate 403. After sterilization, the operation of the fan 4 causes the gas inside the isolator body 1 to enter the interior of the connecting pipe 402 through the collecting plate 403, and then be discharged through the ventilation box 101. After discharge, the operation of the servo motor 411 causes the threaded rod 409 to rotate, which facilitates the upward movement of the toothed plate 407 on the sleeve 408, causing the collecting plate 403 on the toothed ring 406 to rotate. Then, the second semicircular plate 405 and the first semicircular plate 404 seal the outlet of the connecting pipe 402, isolating it from the outside air and preventing the outside air from entering the interior of the isolator body 1 and causing pollution.

[0033] Finally, it should be noted that the above are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A sterile isolator with ventilation and filtration functions, characterized in that, include: The isolator body has a ventilation box fixedly installed at the center of its surface, a door installed on the surface of the isolator body, a transparent glass fixedly installed on the surface of the door, a rubber glove fixedly installed on the surface of the transparent glass, and a transfer rack installed inside the isolator body. It also includes a sliding component, a limiting component, and a ventilation component. The sliding component is disposed inside the isolator body for horizontal movement of the docking frame. The limiting component is disposed on the base plate for fixing the item. The ventilation component is disposed inside the ventilation box for drawing air from inside the isolator body. The sliding assembly includes a pair of rods fixedly installed inside the isolator body. A pulley is slidably connected to each rod, and the pulley is rotatably connected to the docking frame. Through slots are provided on both sides of the docking frame. A clamping plate is provided inside the docking frame, and an arc-shaped groove is provided at the top of the clamping plate. The inner wall of the arc-shaped groove is attached to the surface of the rod. Side seats are fixedly connected to both sides of the clamping plate. One end of each side seat extends through the through slot to the outside of the docking frame. The side seat is slidably connected to a side rod. The bottom end of the side rod is fixedly connected to a shaft seat, which is fixedly connected to the docking frame. A collar is fixedly connected to the top of the side rod, and a spring is fitted onto the side rod. The two ends of the spring are fixedly connected to the top surface of the side seat and the bottom surface of the collar, respectively. A crossbar is rotatably connected to the docking frame. A handle is fixedly connected to the middle of the crossbar, and cams are fixedly connected to both ends of the crossbar. The cams are attached to the bottom surface of a sliding plate, which is fixedly installed on the bottom surface of the clamping plate. The limiting component includes a base plate fixedly connected to the bottom surface of the docking frame. A first damping rod is rotatably connected to the bottom end of the base plate. An arm plate is fixedly connected to the first damping rod. A second damping rod is rotatably connected to the other end of the arm plate. A bracket is fixedly connected to the middle end of the second damping rod.

2. A sterile isolator with ventilation and filtration function according to claim 1, characterized in that: The bracket has insert rods that can be movably inserted at both ends. The bottom end of the insert rod is fixedly connected to a ring, and bolts are threaded onto the surface of the ring.

3. A sterile isolator with ventilation and filtration function according to claim 2, characterized in that: The ventilation assembly includes a fan fixedly installed inside the ventilation box. A pipe is fixedly connected to the bottom of the fan. A connecting pipe is fixedly connected to the surface of the pipe laterally. An air collecting plate is rotatably connected to the connecting pipe. The air collecting plate is located inside the isolator body.

4. A sterile isolator with ventilation and filtration function according to claim 3, characterized in that: A first semicircular plate is fixedly connected to the opening of the connecting pipe, and a second semicircular plate is fixedly connected to the inner wall of the gas collecting plate. The second semicircular plate is attached to one end of the connecting pipe.

5. A sterile isolator with ventilation and filtration function according to claim 4, characterized in that: A toothed ring is fixedly connected to the air collecting plate, and a toothed plate meshes with the toothed ring. A sleeve is fixedly connected to the bottom end of the toothed plate, and a threaded rod is threadedly connected to the sleeve. The bottom end of the threaded rod is rotatably connected to a horizontal plate. Both ends of the horizontal plate are fixedly connected to the inner wall of the ventilation box. The bottom end of the threaded rod is fixedly connected to the output end of a servo motor. The servo motor is fixedly installed at the middle of the bottom surface of the horizontal plate. A filter plate is installed at the top of the ventilation box.

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