Cryopreservation tube for storing blood clots

By connecting the cutting parts and carriers on the inner wall of the frozen storage tube, efficient cut-off and assembly of blood clots is achieved, and cross-contamination and waste of samples caused by unclean cleaning of glass rods and spoons is solved, and the experimental results are improved accuracy and sample preservation efficiency.

CN222197014UActive Publication Date: 2024-12-20ZHONGSHAN THIRD PEOPLES HOSPITAL (ZHONGSHAN MENTAL HEALTH & MENTAL HYGIENE PREVENTION & TREATMENT CENT)
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Patent Information

Application Number
CN202420866833.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-24
Publication Date
2024-12-20
Estimated Expiration
2034-04-24

AI Technical Summary

Technical Problem

When existing frozen storage tubes are aliquoted and stored in blood clots, the glass rod and spoon are not cleaned and the sample is cross-contaminated, affecting the accuracy of the experimental results and causing waste of biological samples.

Method used

A frozen storage tube is designed, with the inner wall connecting the cutting parts and the fixed connection carrier, which can cut and disassemble blood clots under one-hand operation, avoiding the cleaning process of glass rods and spoons, ensuring sealing and disassembly. efficiency.

Benefits of technology

It effectively avoids cross-contamination of samples, saves time, reduces experimental errors and sample waste, and prevents sample degradation problems caused by freeze-thaw.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a cryopreservation tube for storing blood clots. The cryopreservation tube comprises a tube body, a tube cover, a cutting part and a bearing part, the cutting piece is used for cutting off blood clots and is connected with the inner wall of the tube body; an opening is formed in the upper portion of the pipe body, and a containing cavity is formed in the pipe body. One end of the bearing piece is fixedly connected with the pipe cover, and the other end of the bearing piece extends into the containing cavity of the pipe body. The cutting piece in the cryopreservation tube can cut off blood clots, the bearing piece fixedly connected to the middle portion of the tube cover can assist the cutting piece in cutting off the blood clots and then subpackaging the blood clots into the cryopreservation tube, and the blood clots can be conveniently stored through one-hand operation; according to the cryopreservation tube, the blood clots do not need to be triturated by an extra glass rod and sub-packaged and stored by a medicine spoon, and the glass rod and the medicine spoon do not need to be cleaned, so that the time is saved; the problems that the risk of cross contamination between blood clot samples is caused due to the fact that used glass rods and medicine spoons are not cleaned thoroughly, later experiment results are wrong, and biological samples are wasted are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of biomedical consumables, in particular to a cryopreservation tube for storing blood clots. Background Art

[0002] A blood clot, whose full name is blood clot, refers to the phenomenon that red blood cells in the blood aggregate into lumps under the action of chemical reagents, toxic substances, biological substances, temperature, etc. After coagulation, the blood changes from a sol state to a gel state of a blood clot. For example, under the action of the fibrin network, red blood cells are gathered together to form a blood clot.

[0003] The blood clot is in gel form. The existing blood clot freezing procedure is to use a glass rod to gently crush the blood clot and then use a medicine spoon to dispense it into ordinary cryopreservation tubes. In this process, the glass rod is mixed and the medicine spoon is dispensed, which takes a long time. In addition, when a large number of samples need to be frozen, there is a shortage of glass rods and medicine spoons. The general treatment method is to directly rinse the glass rods and medicine spoons and recycle them. This process is time-consuming and laborious. There is also a situation where the glass rods and medicine spoons are not completely cleaned, resulting in the risk of cross-contamination between samples, which in turn causes inaccurate experimental results and waste of biological samples in the later stage. Utility Model Content

[0004] In order to solve the problem that the glass rods and medicine spoons used in the existing cryopreservation tubes for packaging and storing blood clots are not cleaned properly, resulting in the risk of cross contamination between samples, thereby causing inaccurate later experimental results and waste of biological samples, the utility model provides a cryopreservation tube for storing blood clots.

[0005] According to the first aspect of the utility model, there is provided a cryotube for storing blood clots, the cryotube comprising a tube body, a tube cover, a cutting piece and a supporting piece; the cutting piece is used to cut off the blood clot, and the cutting piece is connected to the inner wall of the tube body; an opening is provided on the top of the tube body, and a accommodating cavity is provided inside the tube body; one end of the supporting piece is fixedly connected to the tube cover, and the other end of the supporting piece extends into the accommodating cavity of the tube body.

[0006] Preferably, one end of the cutting piece is hinged to the inner wall of the tube body through a hinge axis, the other end of the cutting piece extends out of the tube body, and the hinge axis is parallel to the opening direction of the tube body, and the diameter of the tube body is greater than the length of the cutting piece.

[0007] Preferably, the tube cover comprises a tube cap and a connecting column, and the outer wall of the connecting column is connected to the inner wall of the tube body by threads.

[0008] Preferably, the outer wall of the tube cap is provided with anti-slip grooves.

[0009] Preferably, the inner wall of the tube cover is connected to the outer wall of the tube body by threads, and the outer wall of the tube cover is provided with anti-slip grooves.

[0010] Preferably, a sealing member is provided on the tube cover, and the sealing member is used to seal the tube cover and the tube body.

[0011] Preferably, a card slot is provided on the tube cover.

[0012] Preferably, the tube cover is connected to the tube body via a connecting strip.

[0013] Preferably, the above-mentioned cryopreservation tube also includes a base, which is used to support the tube body, and the base is detachably connected to the tube body.

[0014] Preferably, the outer wall of the tube body is provided with a capacity scale.

[0015] Preferably, an identification QR code is provided at the bottom of the base.

[0016] Compared with the prior art, the beneficial effects of the utility model are:

[0017] The cryopreservation tube provided by the utility model has a cutting piece connected to the inner wall of the tube body, and a supporting piece fixedly connected to the tube cover. When pouring the blood clot from the blood collection tube into the cryopreservation tube for packaging and storage, the cutting piece can cut off the blood clot, and the supporting piece fixedly connected to the middle part of the tube cover can assist the cutting piece in cutting off the blood clot and then packaging it into the cryopreservation tube, which is convenient for one-handed operation to store the blood clot. Compared with the traditional cryopreservation tube for packaging and storing blood clots, the cryopreservation tube provided by the utility model does not need to use a glass rod to crush the blood clot and a medicine spoon to package and store the blood clot, and does not need to clean the glass rod and the medicine spoon, which saves time and avoids the risk of cross-contamination between blood clot samples due to unclean cleaning of the glass rod and the medicine spoon, as well as the problem of incorrect experimental results and waste of biological samples in the later stage. Moreover, when there are a large number of blood clots, compared with directly storing a large number of blood clots in the same cryopreservation tube, using the cryopreservation tube provided by the utility model to divide and store the blood clots is convenient for subsequent experiments and can prevent the blood clot samples in the same cryopreservation tube from being degraded and unusable due to repeated freezing and thawing. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the structure of the internally rotating cryogenic storage tube provided in Example 1.

[0019] Figure 2 A schematic diagram of the structure of the counterclockwise rotation of the cutting piece in the internally rotating cryogenic tube provided in Example 1 and a top view of the opening of the cryogenic tube.

[0020] Figure 3 This is a schematic diagram of the structure of the externally rotating cryogenic storage tube provided in Example 2.

[0021] Figure numerals: 1 tube body, 2 tube cover, 3 cutting piece, 4 bearing piece, 5 accommodating cavity, 6 hinge shaft, 7 tube cap, 8 connecting column, 9 thread, 10 anti-slip pattern, 11 sealing piece, 12 card slot, 13 connecting belt, 14 base, 15 capacity scale, 16 identification QR code. DETAILED DESCRIPTION

[0022] The following is a further clear and complete description of the technical features of the technical solution provided by the utility model in conjunction with the specific implementation methods. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by those skilled in the art without creative work are within the scope of protection of the utility model.

[0023] Example 1

[0024] This embodiment provides a cryotube for storing blood clots. The cryotube is an internally rotating cryotube, and its structural schematic diagram is shown in FIG. Figure 1 As shown, the cryopreservation tube includes a tube body 1, a tube cover 2, a cutting piece 3 and a supporting piece 4; the cutting piece 3 is used to cut off blood clots, and the cutting piece 3 is connected to the inner wall of the tube body 1; an opening is provided on the top of the tube body 1, and a accommodating cavity 5 is provided inside the tube body 1; one end of the supporting piece 4 is fixedly connected to the tube cover 2, and the other end of the supporting piece 4 extends into the accommodating cavity 5 of the tube body 1.

[0025] The cryopreservation tube provided in this embodiment has a cutting piece connected to the inner wall of the tube body and a supporting piece fixedly connected to the tube cover. When pouring the blood clot from the blood collection tube into the cryopreservation tube for packaging and storage, the cutting piece can cut off the blood clot, and the supporting piece fixedly connected to the middle part of the tube cover can assist the cutting piece in cutting off the blood clot and then packaging it into the cryopreservation tube, which is convenient for one-handed operation to store the blood clot. Compared with the traditional cryopreservation tube for packaging and storing blood clots, the cryopreservation tube provided in this embodiment does not need to use a glass rod to crush the blood clot and a medicine spoon to package and store the blood clot. There is no need to clean the glass rod and the medicine spoon, which saves time and avoids the risk of cross-contamination between blood clot samples due to unclean cleaning of the glass rod and the medicine spoon, as well as the problem of incorrect experimental results and waste of biological samples in the later stage. Moreover, when there are a large number of blood clots, compared with directly storing a large number of blood clots in the same cryopreservation tube, using the cryopreservation tube provided by the utility model to divide and store the blood clots is convenient for subsequent experiments and can prevent the blood clot samples in the same cryopreservation tube from being degraded and unusable due to repeated freezing and thawing.

[0026] Further, see Figure 2The schematic diagram of the structure of the cutting piece in the internally rotating cryogenic tube rotating counterclockwise and the top view of the tube mouth of the cryogenic tube are shown. In this embodiment, one end of the cutting piece 3 is hinged to the inner wall of the tube body 1 through the hinge shaft 6, and the other end of the cutting piece 3 extends out of the tube body 1, and the hinge shaft 6 is parallel to the opening direction of the tube body 1, and the diameter of the tube body 1 is greater than the length of the cutting piece 3.

[0027] On the basis of the above structure, when using the cryopreservation tube of the utility model, during use, the carrier 4 can be used to carry the blood clot and the blood clot can be cut off by using the cutting piece 3 that extends out of one end of the tube body 1, and then the carrier 4 carrying the blood clot can be extended into the accommodating cavity 5 of the tube body 1 and the blood clot can be packed into the tube body 1. Since the length of the cutting piece 3 is smaller than the diameter of the tube body 1 and one end of the cutting piece 3 is hinged to the inner wall of the tube body 1 through the hinge shaft 6, after the blood clot is packed into the tube body 1, the carrier 4 can be used to rotate the end of the cutting piece 3 that extends out of the tube body 1 counterclockwise along the hinge shaft 6 so that the cutting piece 3 is flipped into the accommodating cavity 5 of the tube body 1 and is parallel to the opening direction of the tube body 1 or folded to the inner wall of the tube body 1. The above arrangement can ensure that the carrier 4 will not extend out of the tube body 1 after cutting off the blood clot, and will not affect the sealing between the tube cover 2 and the tube body 1 of the cryopreservation tube.

[0028] Figure 2 The cutting member 3 shown is a top view when the end of the cutting member 3 extending out of the tube body 1 is flipped along the hinge axis 6 into the accommodating cavity 5 of the tube body 1 by the supporting member 4 and parallel to the plane direction of the tube mouth of the tube body 1.

[0029] Furthermore, the tube cover 2 includes a tube cap 7 and a connecting column 8 , and the outer wall of the connecting column 8 is connected to the inner wall of the tube body 1 via a thread 9 .

[0030] Furthermore, the outer wall of the pipe cap 7 is provided with anti-slip grooves 10 .

[0031] By providing the anti-slip grooves 10 on the outer wall of the tube cap 7, the risk of the tube cover 2 slipping or falling off due to the smooth outer wall of the tube cap 7 when the cryotube is in use can be reduced.

[0032] Furthermore, a sealing member 11 is provided on the tube cover 2 , and the sealing member 11 is used to seal the tube cover 2 and the tube body 1 .

[0033] By providing a sealing member 11, such as a rubber sealing ring, on the tube cover 2, when the tube cover 2 is connected to the tube body 1 by rotation, the sealing between the tube cover 2 and the tube body 1 can be improved, thereby reducing the risk of blood clots or liquid seeping out of the cryopreservation tube during storage or transfer.

[0034] Furthermore, a slot 12 is provided on the tube cover 2 .

[0035] When using external testing equipment to test the sample in the cryotube, the tube cover 2 can be provided with a card slot 12 whose structure can match the structure of the manipulator of the external testing equipment, so as to facilitate automated sample injection testing.

[0036] Furthermore, the tube cover 2 is connected to the tube body 1 via a connecting strip 13 .

[0037] The tube cover 2 is connected to the tube body 1 by the connecting belt 13, so that the tube cover 2 can be prevented from being lost during the use of the cryopreservation tube.

[0038] Furthermore, the cryotube also includes a base 14, which is used to support the tube body 1, and the base 14 is detachably connected to the tube body 1.

[0039] By providing a base 14 for supporting the tube body 1 at the bottom of the cryotube, there is no need to hold the tube body 1 of the cryotube in hand during the operation of packaging and storing the blood clot, so that the cryotube can stand stably on the laboratory table, which is more convenient to operate.

[0040] Furthermore, the outer wall of the tube body 1 is provided with a capacity scale 15 , and the bottom of the base 14 is provided with an identification QR code 16 .

[0041] Providing a volume readable mark 15 on the outer wall of the tube body 1 of the cryotube is beneficial for quantitative packaging and storage of blood clots, while providing an identification QR code at the bottom of the base 14 can facilitate the distinction between different biological samples and avoid confusion.

[0042] Example 2

[0043] This embodiment provides a cryopreservation tube for storing blood clots. Compared with Embodiment 1, the difference is that the cryopreservation tube provided in this embodiment is an externally rotating cryopreservation tube, the inner wall of the tube cover 2 is connected to the outer wall of the tube body 1 through a thread 9, and the outer wall of the tube cover 2 is provided with an anti-slip pattern 10. The structural diagram thereof is shown in FIG. Figure 3 Except for the above differences, other structures of the cryopreservation tube provided in this embodiment are strictly consistent with those in Example 1.

[0044] The above embodiments are only used to illustrate the technical solution of the utility model rather than to limit the protection scope of the utility model. Although the utility model is described in detail with reference to the above embodiments, ordinary technicians in the relevant field should understand that the technical solution of the utility model can be modified or replaced by equivalents, but these modifications or replacements are all within the protection scope of the utility model.

Claims

1. A cryotube for storing blood clots, characterized in that: The freezing tube comprises a tube body (1), a tube cover (2), a cutting piece (3) and a bearing piece (4); The cutting piece (3) is used to cut off the blood clot, and the cutting piece (3) is connected to the inner wall of the tube body (1); An opening is provided on the top of the tube body (1), and a receiving cavity (5) is provided inside the tube body (1); One end of the carrier (4) is fixedly connected to the tube cover (2), and the other end of the carrier (4) extends into the accommodating cavity (5) of the tube body (1).

2. The cryotube for storing blood clots according to claim 1, characterized in that: One end of the cutting piece (3) is hinged to the inner wall of the tube body (1) via a hinge shaft (6), the other end of the cutting piece (3) extends out of the tube body (1), and the hinge shaft (6) is parallel to the opening direction of the tube body (1), and the diameter of the tube body (1) is greater than the length of the cutting piece (3).

3. The cryotube for storing blood clots according to claim 1, characterized in that: The tube cover (2) comprises a tube cap (7) and a connecting column (8), and the outer wall of the connecting column (8) is connected to the inner wall of the tube body (1) via a thread (9).

4. The cryotube for storing blood clots according to claim 3, characterized in that: The outer wall of the pipe cap (7) is provided with anti-slip grooves (10).

5. The cryotube for storing blood clots according to claim 1, characterized in that: The inner wall of the tube cover (2) is connected to the outer wall of the tube body (1) via a thread (9), and the outer wall of the tube cover (2) is provided with anti-slip grooves (10).

6. The cryotube for storing blood clots according to claim 1, characterized in that: The tube cover (2) is provided with a sealing member (11), and the sealing member (11) is used to seal the tube cover (2) and the tube body (1).

7. The cryotube for storing blood clots according to claim 1, characterized in that: The tube cover (2) is provided with a clamping slot (12).

8. The cryotube for storing blood clots according to claim 1, characterized in that: The tube cover (2) is connected to the tube body (1) via a connecting belt (13).

9. The cryotube for storing blood clots according to claim 1, characterized in that: The cryogenic tube further comprises a base (14), wherein the base (14) is used to support the tube body (1), and the base (14) is detachably connected to the tube body (1).

10. The cryotube for storing blood clots according to claim 9, characterized in that: The outer wall of the tube body (1) is provided with a capacity scale (15), and the bottom of the base (14) is provided with an identification two-dimensional code (16).