Continuous liquid adding plate washing device
By designing a continuous liquid-adding and washing device, the cleaning effect and efficiency of the enzyme label plate is improved by using the structure of the handheld part and the catheter part, and the problems of high background signal and discontinuous cleaning in traditional methods are solved, achieving more accurate and efficient Experimental results.
Patent Information
- Application Number
- CN202323251191.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2023-11-30
- Publication Date
- 2024-12-20
- Estimated Expiration
- 2033-11-30
AI Technical Summary
In ELISA enzyme-linked immunosorbent assay, it is difficult for the existing technology to effectively clean the enzyme label plate, resulting in high background signal and low analytical signal-to-noise ratio. In addition, traditional plate washing machines cannot achieve continuous liquid cleaning, which affects the accuracy and efficiency of the test results. .
A continuous liquid-adding and washing plate device is designed, including a handheld part, a suspension arm, a pressing structure, a conduit part and a liquid outlet. The piston is controlled by a manual control system to accelerate the flow of the washing liquid pressure, combined with a return spring to achieve continuous water suction and drainage, and a filter head is set Prevent impurities from entering and facilitate maintenance and storage through a detachable structure.
Improves cleaning effect and efficiency, ensures that the water output of each liquid outlet is uniform, avoids the problem of insufficient liquid output in traditional methods, and realizes automatic reset and water absorption through continuous liquid addition, simplifies operation and reduces the risk of impurities blockage. .
Smart Images
Figure CN222198025U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of testing equipment cleaning, and in particular relates to a continuous liquid-adding plate washing device. Background Art
[0002] ELISA enzyme-linked immunosorbent assay is to bind a known antigen or antibody to the surface of a solid phase carrier, then incubate it with an enzyme-labeled antibody or antigen, and then develop color through a color developer. The depth of color development is proportional to the content of the substance to be tested and can be observed with the naked eye. In an ELISA experiment, there are three necessary reagents: a known antigen or antibody; an enzyme-labeled antibody or antigen; and a color developer. There are four common ELISA experiments: direct ELISA, indirect ELISA, sandwich ELISA, and competitive ELISA.
[0003] ELISA plates play a key role in ELISA. One of the key points in optimizing ELISA is washing, and there are two ways to wash the plate: manual washing and plate washing with a plate washer. The washing step reduces the background signal caused by unbound antibodies, thereby increasing the signal-to-noise ratio of the analysis. Washing between each step ensures that only specific binding events are retained to generate a signal in the final step. Insufficient washing can lead to differences and high background, affecting the test results.
[0004] The problem with the prior art is how to improve the cleaning effect and ensure the accuracy of the experimental results when cleaning the ELISA plate; and how to improve the cleaning efficiency when cleaning the wells on the ELISA plate is a problem that needs to be solved. Summary of the invention
[0005] The utility model aims to provide a continuous liquid-adding plate-washing device for solving the problems in the prior art, which has the advantages of good cleaning effect, high efficiency and convenient use.
[0006] To achieve the above-mentioned purpose, the technical solution adopted by the utility model is: a continuous liquid-adding plate washing device, comprising a hand-held part, a suspension arm is arranged on the hand-held part, a accommodating cavity is opened in the middle of the hand-held part, a pressing structure is slidably arranged on the top of the hand-held part, a connecting part is arranged at the lower end of the pressing structure, a piston for cooperating with the inner cavity of the hand-held part is arranged on the connecting part, a return spring is arranged between the connecting part and the top end of the hand-held part, the bottom end of the hand-held part includes a necking part, the bottom end of the necking part is connected to a conduit part, the conduit part is connected to a liquid outlet part, a plurality of liquid outlet nozzles distributed along a straight line are arranged at the bottom of the liquid outlet part, a plurality of linear channels for connecting the conduit part and the liquid outlet nozzle are arranged on the liquid outlet part, a liquid inlet is arranged on the hand-held part, the liquid inlet is connected to a water inlet pipe, a telescopic hose section is arranged at the water outlet end of the water inlet pipe, and a one-way valve is arranged at the liquid inlet and the conduit part.
[0007] In the above scheme, the hand-held part is used for human hand grasping, and the pressing structure is controlled by the hand to drive the piston on the connecting part to press down to provide pressure to the washing liquid in the accommodating chamber. When the washing liquid passes through the constricted part, it is compressed by the side wall pressure and flows downward at an accelerated speed. The washing liquid passes through the conduit part and the straight channel in turn and is discharged from the liquid outlet. The straight channel is set to make the water output at each liquid outlet uniform to avoid the problem of insufficient liquid output on both sides. The holes and grooves on the test plate are cleaned. After the drainage is completed, under the action of the reset spring, the connecting part moves upward and resets, and negative pressure is formed in the accommodating chamber to absorb the washing liquid from the water inlet pipe, and the next drainage and cleaning can be carried out continuously. The telescopic hose section of the water inlet pipe can facilitate the angle adjustment of the water inlet pipe, which is convenient for operation. The suspension arm on the hand-held part is used for hanging and placing when not in use. The above structure forms a hand-held cleaning mechanism, which is convenient for hand-held cleaning operations.
[0008] Furthermore, a filter head is provided at the water inlet end of the water inlet pipe.
[0009] A filter head is arranged at the end of the water inlet pipe to filter the washing liquid, thereby preventing impurities from entering the accommodating cavity, thereby affecting the cleaning effect and causing clogging of the liquid outlet.
[0010] Furthermore, the filter head is arranged in a water tank, and a placement box is detachably arranged on a side wall of the water tank.
[0011] The water tank is used to store the washing liquid, which is convenient for the water inlet pipe to absorb. The placement box is used to store the handheld cleaning mechanism. The suspension arm can be used to cooperate with the side wall of the placement box for suspension. When hanging, the liquid outlet nozzle is placed in the placement box to prevent the liquid outlet nozzle from being damaged or impurities from entering.
[0012] Furthermore, a tank opening is arranged on the top of the water tank, and a tank cover for cooperating with the tank opening is arranged on the water inlet pipe.
[0013] By arranging the water inlet pipe to penetrate the tank cover, it is convenient to draw the washing liquid from the water tank, while preventing impurities from entering the tank body through the tank opening.
[0014] Furthermore, an opening is provided at the top of the placement box, engaging structures are provided on both sides of the placement box, and a hook structure for cooperating with the engaging structure is provided on the side wall of the water tank.
[0015] The top opening of the placement box is convenient for placing the handheld cleaning mechanism, and the detachable connection between the snap-fit structure and the hook structure facilitates the cleaning of the placement box, and the structure is simple and easy to manufacture.
[0016] Furthermore, the liquid outlet portion and the liquid outlet nozzle are detachably connected.
[0017] The liquid outlet nozzle is detachably connected to the liquid outlet part, which is convenient for replacement and maintenance when the liquid outlet nozzle is blocked.
[0018] Furthermore, the liquid outlet nozzle includes a threaded connector and a water outlet needle arranged in the middle of the threaded connector, and the bottom of the liquid outlet portion is provided with a plurality of threaded holes for cooperating with the threaded connector.
[0019] The water outlet needle can make the water flow spray out in a concentrated manner to improve the cleaning effect, and the threaded connector and the threaded hole are used to facilitate connection and disassembly.
[0020] Furthermore, the hand-held part and the pressing structure are both cylindrical structures.
[0021] The cylindrical structure is simple and easy to operate.
[0022] Compared with the prior art, the beneficial effects of the utility model are:
[0023] 1. By providing a hand-held part, a constricted part, a conduit part, a liquid outlet part and a liquid outlet nozzle, the washing liquid is discharged downward under pressure under the drive of the pressing structure. During the flow of the washing liquid, the flow channel cross-section is gradually reduced through the constricted part, the conduit part and the liquid outlet nozzle, so that the washing liquid is pressurized and the flow velocity is accelerated, thereby increasing the pressure and speed of the water outlet and improving the cleaning effect. At the same time, multiple linear channels are provided on the liquid outlet part to make the water outlet pressure at each liquid outlet nozzle uniform, thereby avoiding the problem of insufficient water outlet at the liquid outlet nozzles at both ends of the traditional washing mechanism, which affects the cleaning effect;
[0024] 2. By setting a pressing structure, a connecting part, a reset spring, a water inlet pipe and a one-way valve structure, the water is drained and flushed under the action of the pressing structure, and the water is automatically reset and absorbed under the action of the reset spring, so that the mechanism can continuously absorb and drain water to flush the ELISA plate, thereby improving the cleaning efficiency and solving the problem that the traditional cleaning mechanism needs to absorb water multiple times and cannot clean continuously;
[0025] 3. By setting a filter head at the end of the water inlet pipe and cooperating with a detachable liquid outlet structure, impurities can be prevented from clogging the cleaning mechanism and affecting the cleaning effect, making it convenient to clean and replace the liquid outlet;
[0026] 4. A storage box is provided to facilitate the storage of the cleaning mechanism, to prevent the liquid outlet from being contaminated, and to facilitate use. BRIEF DESCRIPTION OF THE DRAWINGS
[0027] Figure 1 This is a structural stereogram of a continuous liquid adding and plate washing device in Example 1 of the utility model;
[0028] Figure 2 This is a structural schematic diagram of a handheld cleaning mechanism in Embodiment 1 of the present utility model;
[0029] Figure 3 This is a schematic diagram of the structure of the liquid outlet nozzle in Example 1 of the utility model;
[0030] Figure 4This is a connection diagram of the filter head in Example 1 of the utility model;
[0031] In the figure: 1. hand-held part; 2. suspension arm; 3. accommodating chamber; 4. pressing structure; 5. connecting part; 6. piston; 7. return spring; 8. necking part; 9. catheter part; 10. liquid outlet; 11. water outlet needle; 12. linear channel; 13. liquid inlet; 14. water inlet pipe; 15. telescopic hose section; 16. one-way valve; 17. filter head; 18. water tank; 19. placement box; 20. box opening; 21. box cover; 22. snap-fit structure; 23. hook structure; 24. threaded hole; 25. polygonal screwing part; 26. external threaded part. DETAILED DESCRIPTION
[0032] The technical solution of the utility model will be clearly and completely described below in conjunction with the drawings in the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative labor are within the scope of protection of the utility model. In the description of the utility model, it should be noted that the terms front, back, left, right, etc. indicating directions or positional relationships are based on the directions or positional relationships shown in the drawings, or the directions or positional relationships in which the utility model product is usually placed when used. They are only for the convenience of describing the utility model or simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed or operated in a specific orientation, and therefore cannot be understood as a limitation on the utility model.
[0033] Example 1
[0034] like Figure 1-4 As shown, a continuous liquid-adding plate washing device comprises a handheld part 1, on which a suspension arm 2 is arranged, a receiving cavity 3 is opened in the middle of the handheld part 1, a pressing structure 4 is slidably arranged on the top of the handheld part 1, a connecting part 5 is arranged at the lower end of the pressing structure 4, a piston 6 for cooperating with the inner cavity of the handheld part 1 is arranged on the connecting part 5, a return spring 7 is arranged between the connecting part 5 and the top end of the handheld part 1, and the bottom end of the handheld part 1 includes a constriction part 8, and the constriction part 8 is provided. The bottom end of the part 8 is connected with a conduit part 9, and the conduit part 9 is connected with a liquid outlet part 10. The bottom of the liquid outlet part 10 is provided with a plurality of liquid outlet nozzles distributed along a straight line, and the liquid outlet part 10 is provided with a plurality of linear channels 12 for connecting the conduit part 9 and the liquid outlet nozzles. The hand-held part 1 is provided with a liquid inlet 13, and the liquid inlet 13 is connected with a water inlet pipe 14. The water outlet end of the water inlet pipe 14 is provided with a telescopic hose section 15. The liquid inlet 13 and the conduit part 9 are both provided with a one-way valve 16.
[0035] In the above scheme, the hand-held part 1 is used for grasping by human hands. The pressing structure 4 is controlled by human hands to drive the piston 6 on the connecting part 5 to press down to provide pressure to the washing liquid in the accommodating chamber 3. When the washing liquid passes through the constricted part 8, it is compressed by the side wall pressure and flows downward at an accelerated speed. The washing liquid passes through the conduit part 9 and the straight channel 12 in sequence and is discharged from the liquid outlet. The straight channel 12 is set to make the water output at each liquid outlet uniform to avoid the problem of insufficient liquid output on both sides. The holes and grooves on the test plate are cleaned. After the drainage is completed, under the action of the reset spring 7, the connecting part 5 moves upward and resets, and negative pressure is formed in the accommodating chamber 3 to absorb the washing liquid from the water inlet pipe 14, so that the next drainage and cleaning can be carried out continuously. The telescopic hose section 15 of the water inlet pipe 14 can facilitate the angle adjustment of the water inlet pipe 14, which is convenient for operation. The suspension arm 2 on the hand-held part 1 is used for hanging and placing when not in use. The above structure forms a hand-held cleaning mechanism, which is convenient for hand-held cleaning operations.
[0036] The number and distribution of the liquid outlet nozzles correspond to the positions of the holes and slots on the plate body, and each liquid outlet nozzle corresponds to a linear channel 12. The telescopic hose section 15 is a telescopic bellows structure. The connecting part 5 is a plastic structure fixed to the pressing structure 4, and is used to connect the piston 6 and the return spring 7.
[0037] Furthermore, a filter head 17 is provided at the water inlet end of the water inlet pipe 14 .
[0038] The filter head 17 is arranged at the end of the water inlet pipe 14 to filter the washing liquid, thereby preventing impurities from entering the accommodating chamber 3, thereby affecting the cleaning effect and causing the liquid outlet to be blocked.
[0039] The filter head 17 is provided with a plurality of filter holes.
[0040] Furthermore, the filter head 17 is disposed in a water tank 18 , and a placement box 19 is detachably disposed on a side wall of the water tank 18 .
[0041] The water tank 18 is used to store the washing liquid, which is convenient for the water inlet pipe 14 to absorb. The placement box 19 is used to store the handheld cleaning mechanism. The suspension arm 2 can be used to cooperate with the side wall of the placement box 19 for suspension. When hanging, the liquid outlet is placed in the placement box 19 to prevent the liquid outlet from being damaged or impurities from entering.
[0042] During storage, a certain amount of washing liquid can be placed in the placement box 19 so that the height of the washing liquid is higher than the bottom of the liquid outlet nozzle to form a liquid seal to avoid contamination by impurities and blockage.
[0043] Furthermore, a tank opening 20 is provided on the top of the water tank 18 , and a tank cover 21 for cooperating with the tank opening 20 is provided on the water inlet pipe 14 .
[0044] By arranging the water inlet pipe 14 to penetrate the tank cover 21 , it is convenient to draw the washing liquid from the water tank 18 , while preventing impurities from entering the tank body through the tank opening 20 .
[0045] The water inlet pipe 14 and the box cover 21 can be fixedly connected or slidably connected.
[0046] Furthermore, an opening is provided at the top of the placement box 19 , and snap-fit structures 22 are provided on both sides of the placement box 19 . A hook structure 23 for cooperating with the snap-fit structure 22 is provided on the side wall of the water tank 18 .
[0047] The top opening of the placement box 19 is convenient for placing the handheld cleaning mechanism. The detachable connection between the snap-fit structure 22 and the hook structure 23 facilitates the cleaning of the placement box 19. The structure is simple and the manufacturing is convenient.
[0048] The engaging structure 22 is a cubic block, and the hook structure 23 is an angular structure, which is formed integrally with the water tank 18. The water tank 18 and the placement box 19 are both made of plastic.
[0049] Furthermore, the liquid outlet portion 10 and the liquid outlet nozzle are detachably connected.
[0050] The liquid outlet nozzle is detachably connected to the liquid outlet portion 10, which is convenient for replacement and maintenance when the liquid outlet nozzle is blocked.
[0051] Furthermore, the liquid outlet nozzle includes a threaded connector and a water outlet needle 11 arranged in the middle of the threaded connector, and the bottom of the liquid outlet portion 10 is provided with a plurality of threaded holes 24 for cooperating with the threaded connector.
[0052] The water flow can be concentratedly sprayed out through the water outlet needle 11 to improve the cleaning effect, and the threaded connector cooperates with the threaded hole 24 to facilitate connection and disassembly.
[0053] The threaded connector includes a polygonal screwing portion 25 and an external threaded portion 26 .
[0054] Furthermore, the hand-held portion 1 and the pressing structure 4 are both cylindrical structures.
[0055] The cylindrical structure is simple and easy to operate.
[0056] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A continuous liquid adding plate washing device, characterized in that: The invention comprises a hand-held part, wherein a suspension arm is arranged on the hand-held part, a receiving cavity is opened in the middle of the hand-held part, a pressing structure is slidably arranged on the top of the hand-held part, a connecting part is arranged at the lower end of the pressing structure, a piston for cooperating with the inner cavity of the hand-held part is arranged on the connecting part, a return spring is arranged between the connecting part and the top end of the hand-held part, the bottom end of the hand-held part comprises a necking part, the bottom end of the necking part is connected with a conduit part, the conduit part is connected with a liquid outlet part, a plurality of liquid outlet nozzles distributed along a straight line are arranged at the bottom of the liquid outlet part, a plurality of linear channels for connecting the conduit part and the liquid outlet nozzle are arranged on the liquid outlet part, a liquid inlet is arranged on the hand-held part, the liquid inlet is connected with a water inlet pipe, a telescopic hose section is arranged at the water outlet end of the water inlet pipe, and a one-way valve is arranged at the liquid inlet and the conduit part.
2. The continuous liquid adding and plate washing device according to claim 1, characterized in that: The water inlet end of the water inlet pipe is provided with a filter head.
3. The continuous liquid adding and plate washing device according to claim 2, characterized in that: The filter head is arranged in the water tank, and a placement box is detachably arranged on the side wall of the water tank.
4. The continuous liquid adding and plate washing device according to claim 3, characterized in that: The top of the water tank is provided with a tank opening, and the water inlet pipe is provided with a tank cover for matching with the tank opening.
5. The continuous liquid adding and plate washing device according to claim 3, characterized in that: The top of the placement box is provided with an opening, both sides of the placement box are provided with snap-fit structures, and the side walls of the water tank are provided with hook structures for cooperating with the snap-fit structures.
6. The continuous liquid adding and plate washing device according to claim 1, characterized in that: The liquid outlet portion and the liquid outlet nozzle are detachably connected.
7. The continuous liquid adding and plate washing device according to claim 6, characterized in that: The liquid outlet nozzle comprises a threaded connector and a water outlet needle arranged in the middle of the threaded connector, and a plurality of threaded holes for matching with the threaded connector are arranged at the bottom of the liquid outlet portion.
8. The continuous liquid adding and plate washing device according to claim 1, characterized in that: The hand-held part and the pressing structure are both cylindrical structures.