Immunofluorescence experiment sample treatment device for pathology department

Abstract

The utility model discloses an immunofluorescence experiment sample processing device for pathology department, and particularly relates to the technical field of biological detection, the immunofluorescence experiment sample processing device comprises a liquid barrel and a leakage basket arranged in the liquid barrel, the upper end opening of the leakage basket is provided with a convex thread, the leakage basket is provided with a sealing cover, and the sealing cover is installed on the convex thread in a threaded manner; the leakage basket is placed in the liquid barrel, and the multiple supporting rods support the biological bottom of the leakage basket. According to the immunofluorescence experiment sample treatment device for the pathology department, the leakage basket is arranged, and the sealing cover is mounted at the upper end opening of the leakage basket in a threaded manner, so that a sample is placed in the leakage basket, the leakage basket is placed in the liquid barrel, and the sample in the leakage basket is blocked by the sealing cover, so that the sample cannot float on the liquid level and is completely soaked in the liquid barrel; meanwhile, the depth in the liquid barrel is greater than the height of the leakage basket, so that the sample in the leakage basket can be completely immersed in the liquid barrel, and the sample can be fully soaked with the liquid in the liquid barrel.

Description

Technical Field

[0001] The utility model relates to the technical field of biological detection, in particular to an immunofluorescence experiment sample processing device for pathology. Background Art

[0002] The samples used in immunofluorescence experiments in pathology are usually tissue cells or body fluids, etc. These samples are representative for immunofluorescence detection and analysis and can reflect the characteristics of the lesion site or specific tissue and contain target antigens.

[0003] A Chinese patent with authorization announcement number CN218584806U discloses an immunofluorescence experiment sample processing device, including a box body, a carrying plate and an immersion component. The immersion component includes a placement basket, a fixed bracket, a fixed push rod, a clamping slide rod, a rotating bolt and a lower pressure plate. The clamping slide rod is slidably connected to the fixed push rod, the rotating bolt is slidably connected to the fixed push rod and abuts against the clamping slide rod, the lower pressure plate is fixedly connected to the clamping slide rod and cooperates with the placement basket. The sample is placed in the placement basket, the placement basket is moved to be placed on the carrying plate and extended into the box body, the clamping slide rod is pulled to extend the length of the clamping slide rod extending out of the fixed push rod, the clamping plate is moved downward, the rotating bolt is tightened to lock the clamping slide rod on the fixed push rod, so that the lower pressure plate presses the sample in the placement basket downward, and then the sample sinks into the antibody in the box body, further improving the immersion effect.

[0004] Since the sample may be a colloid body such as the brain, spinal cord or ovarian follicle, the pressing plate in the above device can only be pressed manually during the pressing process, and the degree of pressing cannot be determined. The colloid sample may be crushed during the pressing process. Utility Model Content

[0005] The main purpose of the utility model is to provide an immunofluorescence experiment sample processing device for pathology, which can effectively solve the problem that when the sample is immersed, the downward pressure is too large and the sample is damaged.

[0006] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0007] A sample processing device for immunofluorescence experiments in pathology department comprises a liquid barrel and a collet basket arranged in the liquid barrel.

[0008] Liquid level observation windows are installed in a circular array on the outer surface of the liquid barrel along its height direction, and support rods are installed in a circular array on the inner bottom wall of the liquid barrel away from its axis;

[0009] An outer convex thread is provided at the upper port of the collet basket, and a sealing cover is provided on the collet basket, and the sealing cover is threadably mounted on the outer convex thread;

[0010] The colander is placed in the liquid barrel, and a plurality of support rods support the bottom of the colander;

[0011] It is defined that the depth in the liquid barrel is greater than the height of the colander, and it is defined that the height of the colander in the liquid barrel shall not be higher than the topmost height of the liquid level observation window.

[0012] Preferably, a limiting ring is fixedly installed at the upper port of the liquid barrel, and a limiting ring block is symmetrically installed on the outer surface of the upper part of the collet basket, and the outer circumference size of the collet basket is consistent with the inner circumference size of the limiting ring.

[0013] Preferably, the limiting ring is symmetrically provided with penetrating grooves, and the two grooves are matched with the two limiting ring blocks.

[0014] Preferably, a handle is fixedly mounted at the top axis of the sealing cover.

[0015] Preferably, three supporting feet are installed in a circular array at the bottom end of the liquid barrel.

[0016] Preferably, a stirring assembly is provided on the liquid barrel, and the stirring assembly includes a motor. A connecting frame is fixedly installed at the axis center of the bottom end of the liquid barrel, and a motor is fixedly installed in the connecting frame. The output shaft of the motor extends to one end of the liquid barrel and a rotating shaft is fixedly installed, and stirring rods are installed in a circular array on the rotating shaft.

[0017] Preferably, a magnetic block is fixedly mounted on the top end of the support rod, and the bottom end of the colander is magnetically attracted to the magnetic block.

[0018] Compared with the prior art, the utility model has the following beneficial effects:

[0019] 1. In the utility model, a colander is provided, and a sealing cover is threadedly installed on the upper port of the colander. When a sample is put into the colander, the colander is placed in a liquid barrel. The sample in the colander is blocked by the sealing cover so that it cannot float on the liquid surface, and is completely immersed in the liquid barrel. At the same time, since the depth in the liquid barrel is greater than the height of the colander, the sample in the colander can be completely immersed in the liquid barrel, so that it is fully impregnated with the liquid in the liquid barrel.

[0020] 2. In the present invention, the stirring assembly is provided to accelerate the flow of the liquid in the liquid barrel, thereby speeding up the reaction speed between the sample and the liquid in the liquid barrel. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0022] Figure 2 It is a schematic diagram of the cross-sectional split structure of the colander and the sealing cover in the utility model;

[0023] Figure 3 It is a schematic diagram of the cross-sectional structure of the liquid barrel of the utility model;

[0024] Figure 4 It is a schematic diagram of the disassembled structure of the stirring component in the utility model.

[0025] In the figure: 1. liquid barrel; 11. limiting ring; 111. slot; 112. liquid level observation window; 12. support rod; 121. magnetic block; 13. connecting frame; 2. collet basket; 21. external convex thread; 22. limiting ring block; 23. sealing cover; 24. handle; 3. stirring assembly; 31. motor; 32. rotating shaft; 321. stirring rod; 4. supporting foot. DETAILED DESCRIPTION

[0026] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0027] Embodiment 1

[0028] like Figure 1-Figure 3 As shown, a sample processing device for immunofluorescence experiment in pathology department comprises a liquid barrel 1 and a collet basket 2 arranged in the liquid barrel 1, liquid level observation windows 112 are installed in a circular array along the height direction on the outer surface of the liquid barrel 1, support rods 12 are installed in a circular array away from the axis of the inner bottom wall of the liquid barrel 1, an outer convex thread 21 is provided at the upper port of the collet basket 2, a sealing cover 23 is provided on the collet basket 2, and the sealing cover 23 is threadedly installed on the outer convex thread 21, the collet basket 2 is placed in the liquid barrel 1, and a plurality of support rods 12 support the biological bottom of the collet basket 2, and the depth in the liquid barrel 1 is defined to be greater than the height of the collet basket 2, and the height of the collet basket 2 in the liquid barrel 1 shall not be higher than the topmost height of the liquid level observation window 112;

[0029] By setting a colander 2, a sealing cover 23 is threadedly installed on the upper end of the colander 2, so that the sample is put into the colander 2, and the colander 2 is placed in the liquid barrel 1. The sample in the colander 2 is blocked by the sealing cover 23 so that it cannot float on the liquid surface, and is completely immersed in the liquid barrel 1. At the same time, since the depth in the liquid barrel 1 is greater than the height of the colander 2, the sample in the colander 2 can be completely immersed in the liquid barrel 1, so that it is fully impregnated with the liquid in the liquid barrel 1, and the amount of liquid in the liquid barrel 1 can be observed by setting a liquid level observation window 112.

[0030] Furthermore, a limit ring 11 is fixedly installed at the upper port of the liquid barrel 1, and a limit ring block 22 is symmetrically installed on the outer surface of the upper part of the collet basket 2, and the outer circumference size of the collet basket 2 is in line with the inner circumference size of the limit ring 11;

[0031] By symmetrically installing the limiting ring block 22 on the outer surface of the upper part of the colander basket 2, the outer circumferential size of the colander basket 2 is matched with the inner circumferential size of the limiting ring 11. When the colander basket 2 is immersed in the liquid barrel 1, the limiting ring 11 and the limiting ring block 22 limit each other to prevent the colander basket 2 from floating in the liquid barrel 1.

[0032] Furthermore, the limiting ring 11 is symmetrically provided with penetrating grooves 111, and the two grooves 111 are adapted to the two limiting ring blocks 22; by setting the two grooves 111 to be adapted to the two limiting ring blocks 22, the collet basket 2 is rotated to align the limiting ring blocks 22 with the grooves 111, thereby taking the collet basket 2 out of the liquid barrel 1.

[0033] Furthermore, a handle 24 is fixedly mounted at the axis center of the top end of the sealing cover 23 ; the handle 24 mounted on the top end of the sealing cover 23 makes it convenient for the user to carry the colander 2 .

[0034] Embodiment 2

[0035] like Figure 4 As shown, a stirring assembly 3 is provided on the liquid barrel 1, and the stirring assembly 3 includes a motor 31. A connecting frame 13 is fixedly installed at the axis center of the bottom end of the liquid barrel 1, and the motor 31 is fixedly installed in the connecting frame 13. The output shaft of the motor 31 extends to one end of the liquid barrel 1 and is fixedly installed with a rotating shaft 32. A stirring rod 321 is installed in a circular array on the rotating shaft 32;

[0036] By arranging the motor 31 to drive the stirring rod 321 to rotate via the rotating shaft 32, the liquid in the liquid barrel 1 is stirred, thereby accelerating the reaction speed between the sample and the liquid.

[0037] Furthermore, a magnetic block 121 is fixedly installed on the top of the support rod 12, and the bottom end of the colander 2 is magnetically attracted to the magnetic block 121; by setting the bottom end of the colander 2 to be magnetically attracted to the magnetic block 121, the liquid in the liquid barrel 1 is prevented from flowing during the stirring process of the stirring rod 321, causing the colander 2 to rotate with the flow and collide with the liquid barrel 1.

[0038] Furthermore, three supporting feet 4 are installed in a circular array at the bottom of the liquid barrel 1; the supporting feet 4 are provided to support the liquid barrel 1 to prevent the connection frame 13 at the bottom of the liquid barrel 1 from touching the bottom.

[0039] It should be noted that the specific installation method of the connection frame 13 and the circuit connection method and control method used in the present invention are all conventional designs and will not be elaborated in detail in the present invention.

[0040] The working principle of the utility model is as follows: a sample is placed in a colander 2, a sealing cover 23 on the colander 2 is tightened, the colander 2 is held by a handle 24, the colander 2 is placed in a liquid barrel 1, the colander 2 is rotated so that the two limiting ring blocks 22 on the colander 2 and the two slots 111 on the limiting ring 11 are mutually offset, thereby limiting the colander 2 in the liquid barrel 1, starting the stirring assembly 3 to stir the liquid in the liquid barrel 1, thereby accelerating the reaction speed between the sample and the liquid, taking out the colander 2, rotating the colander 2 to align the limiting ring block 22 with the slot 111, and then lifting the colander 2 out of the liquid barrel 1 by the handle 24.

[0041] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A sample processing device for immunofluorescence experiments in pathology, comprising a liquid barrel (1) and a collet basket (2) arranged in the liquid barrel (1), characterized in that: Liquid level observation windows (112) are installed in a circular array on the outer surface of the liquid barrel (1) along its height direction, and support rods (12) are installed in a circular array on the inner bottom wall of the liquid barrel (1) away from its axis; An external convex thread (21) is provided at the upper end of the collet basket (2), and a sealing cover (23) is provided on the collet basket (2), and the sealing cover (23) is threadably mounted on the external convex thread (21); The colander (2) is prevented from being in the liquid barrel (1), and a plurality of support rods (12) support the biological bottom of the colander (2); It is defined that the depth inside the liquid barrel (1) is greater than the height of the colander (2), and it is defined that the height of the colander (2) inside the liquid barrel (1) must not be higher than the topmost height of the liquid level observation window (112).

2. The immunofluorescence experiment sample processing device for pathology according to claim 1, characterized in that: A limiting ring (11) is fixedly installed at the upper port of the liquid barrel (1), and a limiting ring block (22) is symmetrically installed on the outer surface of the upper part of the collet basket (2). The outer circumference of the collet basket (2) is in close contact with the inner circumference of the limiting ring (11).

3. The immunofluorescence experiment sample processing device for pathology according to claim 2, characterized in that: The limiting ring (11) is symmetrically provided with penetrating grooves (111), and the two grooves (111) are adapted to the two limiting ring blocks (22).

4. The immunofluorescence experiment sample processing device for pathology according to claim 1, characterized in that: A handle (24) is fixedly mounted at the top axis of the sealing cover (23).

5. The immunofluorescence experiment sample processing device for pathology according to claim 1, characterized in that: Three supporting feet (4) are installed in a circular array at the bottom end of the liquid barrel (1).

6. The immunofluorescence experiment sample processing device for pathology according to claim 1, characterized in that: The liquid barrel (1) is provided with a stirring assembly (3), the stirring assembly (3) comprising a motor (31), a connecting frame (13) is fixedly mounted at the axis center of the bottom end of the liquid barrel (1), the motor (31) is fixedly mounted in the connecting frame (13), an output shaft of the motor (31) extends into the liquid barrel (1) and one end thereof is fixedly mounted with a rotating shaft (32), and stirring rods (321) are mounted in a ring array on the rotating shaft (32).

7. The immunofluorescence experiment sample processing device for pathology according to claim 1, characterized in that: A magnetic block (121) is fixedly mounted on the top end of the support rod (12), and the bottom end of the colander (2) is magnetically attracted to the magnetic block (121).

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