Fixing device for rat back skin radiation experiment model

Abstract

The utility model relates to the technical field of radiation experiments, and discloses a fixing device of a rat back skin radiation experiment model, which comprises a lead light limiting structure, a fixing structure and a supporting structure, the fixing structure is positioned at the lower end of the lead light limiting structure, and the supporting structure is positioned at the middle lower part of the fixing structure. According to the fixing device for the rat back skin radiation experiment model, the needed irradiation shape and size can be selected within the range of 3 * 8cm according to the modeling requirement of an actual rat skin radiation model, and normal tissue is fully protected through the lead light limiting structure on the fixing device; the back skin of the rat is fully extended and exposed through the skin fixing structure; the lead block can be infinitely close to the irradiation area through the bottom supporting structure, and the rat lying on the side is not extruded. The fixing mode only irradiates the skin, and normal tissue is protected to the maximum extent; the problem that a normal tissue is inevitably radiated and cannot be molded to increase the dosage can be solved. The fixing device for the rat skin radiation model is simple, easy to operate and high in repeatability.

Description

Technical Field

[0001] The utility model relates to the technical field of radiation experiments, in particular to a fixing device for a rat back skin radiation experiment model. Background Art

[0002] Radiotherapy is one of the important means of treating tumors, but it is inevitable to cause damage to the skin during radiotherapy. Radiation skin injury is the most common complication of radiotherapy, which seriously affects the effect of radiotherapy and the quality of life of patients. Using rats to construct a radiation skin injury model is an important means to study radiation skin injury.

[0003] Existing animal skin radiation injury models mostly irradiate the buttocks or hind limbs of rats. Lead blocks can only protect the surrounding normal tissues, and the radiation will inevitably irradiate the subcutaneous muscles, bones or organs, which also limits the choice of radiation dose. Under the premise of fully ensuring the safety of experimental animals, the skin is irradiated and the radiation dose can be selected according to the experimental needs.

[0004] Therefore, we need to provide a fixation device for a rat back skin radiation experimental model, which can irradiate the skin under the premise of fully ensuring the safety of experimental animals and can select the radiation dose according to experimental needs. Utility Model Content

[0005] 1. Technical issues to be resolved

[0006] The purpose of the utility model is to provide a fixing device for a rat back skin radiation experimental model, so as to solve the problem that the existing animal skin radiation injury models proposed in the above background technology are mostly irradiated to the buttocks or hind limbs of the rat, the lead block can only protect the surrounding normal tissue, and the radiation will inevitably irradiate the subcutaneous muscles, bones or organs, which also limits the selection of radiation dose.

[0007] (II) Technical solution

[0008] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a fixing device for a rat back skin radiation experimental model, comprising a lead light-limiting structure, a fixing mechanism and a supporting mechanism, wherein the fixing mechanism is located at the lower end of the lead light-limiting structure, and the supporting mechanism is located in the middle of the lead light-limiting structure. The lead light-limiting structure comprises a ceiling, a fixing rod, a limiting frame, and a first fixing frame, wherein the fixing rod is fixedly mounted at the lower end of the right end of the ceiling, the limiting frame is movably mounted at the outer end of the fixing rod, and the first fixing frame is fixedly mounted at the lower end of the fixing rod;

[0009] The lead light-limiting structure also includes a connecting plate, a hydraulic push rod, a first push rod, a second fixed frame, a fixed column and a lead plate. The connecting plate is fixedly installed on the left and right ends of the first fixed frame, the hydraulic push rod is fixedly installed on the front and rear ends of the connecting plate, the first push rod is fixedly installed on the lower end of the hydraulic push rod, the second fixed frame is fixedly installed on the lower end of the first push rod, the fixed column is fixedly installed on the lower end of the right end of the second fixed frame, and the lead plate is fixedly installed on the lower end of the fixed column. The connecting plate fixes the hydraulic push rod to improve the fixation. The hydraulic push rod is convenient for pushing the first push rod to cover the rat with the lead plate to protect the rat and fix the organic glass sheet, thereby improving the practicality. The second fixed frame fixes the lead plate, and the lead plate can be customized according to the mold making needs. The shape and size of the appropriate lead plate and the corresponding irradiation area on the lead plate are improved, thereby improving the usability.

[0010] Preferably, the fixing mechanism includes an irradiation area, a plexiglass sheet, a magnet, an irradiation field and a skin support. The irradiation area is fixedly arranged at the upper end of the lead plate. The irradiation area is convenient for the irradiation head to conduct experiments. The size and shape can be selected within 3*8cm according to the molding needs. The irradiation area is integrally cast on the lead plate.

[0011] Preferably, the plexiglass sheet is movably mounted on the lower end of the lead plate, and the magnet is fixedly mounted on the left and right ends of the plexiglass sheet. The plexiglass sheet uses two 3*8*Acm plexiglass sheets, and the magnets are four 1.5*1*0.5cm magnets, which are fixed with glue in the middle of the 3cm wide sides of the two plexiglass sheets to ensure that the two magnets on the same plexiglass sheet are in the same magnetic field direction.

[0012] Preferably, the irradiation field is fixedly set in the middle of the organic glass sheet, and the skin bracket is movably installed at the lower end of the organic glass sheet. The corresponding irradiation area of ​​the irradiation field is outlined with a gentian violet marker to facilitate experimental accuracy. The height B of the skin bracket is made by 3D printing to produce a 3*6*Bcm bracket, or the bracket is made of materials of corresponding materials according to irradiation needs, so as to ensure that the rat lying on its side is not squeezed, and the lead plate irradiation area can be infinitely close to the rat skin irradiation area.

[0013] Preferably, the supporting mechanism includes an electric push rod, a second push rod, an irradiator and an irradiation head. The electric push rod is fixedly installed in the middle of the lower end of the ceiling. The electric push rod pushes the second push rod to move the irradiation head toward the experimental object, thereby improving practicality.

[0014] Preferably, the second pushing rod is fixedly mounted on the lower end of the electric pushing rod, the irradiator is fixedly mounted on the lower end of the second pushing rod, and the irradiation head is fixedly mounted on the lower end of the irradiator. The second pushing rod fixes the irradiator, thereby improving the fixation. There are four irradiation heads, which can simultaneously model four rats, thereby improving efficiency.

[0015] Compared with the prior art, the beneficial effects of the utility model are:

[0016] 1. The fixing device of the rat back skin radiation experimental model realizes the fixing of the connecting plate to the hydraulic push rod by installing the lead light-limiting structure, thereby improving the fixation. The hydraulic push rod facilitates pushing the first push rod to cover the rat with the lead plate to protect the rat and fix the organic glass sheet, thereby improving the practicality. The second fixing frame fixes the lead plate, and the shape and size of the appropriate lead plate and the corresponding irradiation area on the lead plate can be customized according to the needs of model making, thereby improving the protection of the rat by the fixing device of the rat back skin radiation experimental model;

[0017] 2. The fixing device of the rat back skin radiation experimental model, through the installation of the fixing mechanism, realizes that the irradiation area is convenient for the irradiation head to conduct experiments. The organic glass sheet uses two 3*8*Acm organic glass sheets, and the magnets use four 1.5*1*0.5cm magnets, which are respectively fixed with glue in the middle of the 3cm wide sides of the two organic glass sheets to ensure that the two magnets of the same organic glass sheet are in the same magnetic field direction. The irradiation field is outlined with a gentian violet marker pen to facilitate the accuracy of the experiment. The height B of the skin bracket is made of a 3*6*Bcm bracket by 3D printing, or the bracket is made of materials of corresponding materials according to the irradiation needs, which improves the accuracy and repeatability of the fixing device of the rat back skin radiation experimental model;

[0018] 3. The fixing device of the rat back skin radiation experimental model, through the installation of the supporting mechanism, realizes that the electric push rod pushes the second push rod to move the irradiation head toward the experimental object, thereby improving practicality. The second push rod fixes the irradiator, thereby improving fixation. There are four irradiation heads that can simultaneously model four rats, thereby improving efficiency and improving the experimental accuracy of the fixing device of the rat back skin radiation experimental model. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0020] Figure 2 This is a schematic diagram of the fixing mechanism structure of the utility model;

[0021] Figure 3 This is a schematic diagram of the support mechanism structure of the utility model;

[0022] Figure 4 It is a partial enlarged structural schematic diagram of the lead light-limiting structure of the utility model.

[0023] In the figure: 1. Lead light-limiting structure; 101. Ceiling; 102. Fixing rod; 103. Limiting frame; 104. First fixing frame; 105. Connecting plate; 106. Hydraulic push rod; 107. First pushing rod; 108. Second fixing frame; 109. Fixing column; 110. Lead plate; 2. Fixing mechanism; 201. Irradiation area; 202. Organic glass sheet; 203. Magnet; 204. Irradiation field; 205. Skin bracket; 3. Support mechanism; 301. Electric push rod; 302. Second pushing rod; 303. Irradiator; 304. Irradiation head. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] See also Figure 1-Figure 4 The utility model provides a technical solution: a fixing device for a rat back skin radiation experimental model, comprising a lead light-limiting structure 1, a fixing mechanism 2 and a supporting mechanism 3, wherein the fixing mechanism 2 is located at the lower end of the lead light-limiting structure 1, and the supporting mechanism 3 is located in the middle of the lead light-limiting structure 1, and the lead light-limiting structure 1 comprises a ceiling 101, a fixing rod 102, a limiting frame 103, and a first fixing frame 104, wherein the fixing rod 102 is fixedly mounted at the lower end of the right end of the ceiling 101, the limiting frame 103 is movably mounted at the outer end of the fixing rod 102, and the first fixing frame 104 is fixedly mounted at the lower end of the fixing rod 102; The lead light-limiting structure 1 also includes a connecting plate 105, a hydraulic push rod 106, a first push rod 107, a second fixed frame 108, a fixed column 109 and a lead plate 110. The connecting plate 105 is fixedly installed on the left and right ends of the first fixed frame 104, the hydraulic push rod 106 is fixedly installed on the front and rear ends of the connecting plate 105, the first push rod 107 is fixedly installed on the lower end of the hydraulic push rod 106, the second fixed frame 108 is fixedly installed on the lower end of the first push rod 107, the fixed column 109 is fixedly installed on the lower end of the right end of the second fixed frame 108, and the lead plate 110 is fixedly installed on the lower end of the fixed column 109.

[0026] The fixing mechanism 2 includes an irradiation area 201, an organic glass sheet 202, a magnet 203, an irradiation field 204 and a skin support 205. The irradiation area 201 is fixedly mounted on the upper end of the lead plate 110, the organic glass sheet 202 is movably mounted on the lower end of the lead plate 110, the magnet 203 is fixedly mounted on the left and right ends of the organic glass sheet 202, the irradiation field 204 is fixedly set in the middle of the organic glass sheet 202, and the skin support 205 is movably mounted on the lower end of the organic glass sheet 202. The irradiation area 201 is convenient for the irradiation head 304 to perform experiments. The organic glass sheet 202 adopts two A 3*8*Acm organic glass sheet 202 is selected, and four 1.5*1*0.5cm magnets 203 are selected for magnet 203, which are fixed in the middle of the 3cm wide sides of two organic glass sheets 202 with glue to ensure that the two magnets 203 of the same organic glass sheet 202 are in the same magnetic field direction. The irradiation field 204 is outlined with a gentian violet marker to facilitate the accuracy of the experiment. The height B of the skin bracket 205 is made by 3D printing to make a 3*6*Bcm bracket, or the bracket can be made of materials of corresponding materials according to the needs of irradiation.

[0027] The supporting mechanism 3 includes an electric push rod 301, a second push rod 302, an irradiator 303 and an irradiation head 304. The electric push rod 301 is fixedly installed in the middle of the lower end of the ceiling 101, the second push rod 302 is fixedly installed at the lower end of the electric push rod 301, the irradiator 303 is fixedly installed at the lower end of the second push rod 302, and the irradiation head 304 is fixedly installed at the lower end of the irradiator 303. The electric push rod 301 pushes the second push rod 302 to move the irradiation head 304 toward the experimental object, thereby improving practicality. The second push rod 302 fixes the irradiator 303, thereby improving fixation. There are four irradiation heads 304, which can simultaneously model four rats, thereby improving efficiency.

[0028] Working principle: During the experiment, the operator calculates the required thickness of the skin tissue compensation material according to the modeling needs of the rat radiation model, selects the organic glass sheet 202 with the same compensation effect and thickness A, and then cuts two pieces of 3*8*Acm organic glass sheets 202, marks the rat's back with a gentian violet marker, and places the rat on its side to fully extend the back skin and align it with the irradiation field 204 on the organic glass sheet 202, adjust the rat's back skin to ensure skin extension, adjust the rat's position to ensure that the irradiation surface is parallel to the bed surface, and the magnets 203 on both sides of the organic glass sheet 202 clamp the rat's back skin, and the skin bracket 205 prevents the organic glass sheet 202 from ensuring that the back irradiation field 204 is aligned with the lead plate 110 and the irradiation bed surface. The irradiation field 204 is infinitely close to the irradiation area 201 on the lead plate 110, which affects the experimental results. The hydraulic push rod 106 on the connecting plate 105 pushes the first push rod 107 to make the lead plate 110, fix the organic glass sheet 202, and the lead plate 110 can be customized according to the mold making needs. The shape and size of the appropriate lead plate 110 and the corresponding irradiation area 201 on the lead plate 110 are convenient for the irradiation head 304 to conduct experiments and protect rats. The electric push rod 301 pushes the second push rod 302 to move the irradiation head 304 toward the experimental object. The irradiation head 304 has four irradiation heads that can simultaneously model four rats, thereby improving efficiency. The irradiation head 304 verifies the radiotherapy machine through the irradiation area 201.

[0029] Finally, it should be noted that the above content is only used to illustrate the technical solution of the utility model, rather than to limit the protection scope of the utility model. Simple modifications or equivalent substitutions of the technical solution of the utility model by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the utility model.

Claims

1. A fixing device for a rat back skin radiation experimental model, comprising a lead light-limiting structure (1), a fixing mechanism (2) and a supporting mechanism (3), characterized in that: The fixing mechanism (2) is located at the lower end of the lead light-limiting structure (1), and the supporting mechanism (3) is located in the middle of the lead light-limiting structure (1). The lead light-limiting structure (1) comprises a ceiling (101), a fixing rod (102), a limiting frame (103), and a first fixing frame (104). The fixing rod (102) is fixedly mounted at the lower end of the right end of the ceiling (101), the limiting frame (103) is movably mounted on the outer end of the fixing rod (102), and the first fixing frame (104) is fixedly mounted at the lower end of the fixing rod (102); The lead light-limiting structure (1) further comprises a connecting plate (105), a hydraulic push rod (106), a first push rod (107), a second fixed frame (108), a fixed column (109) and a lead plate (110); the connecting plate (105) is fixedly mounted on the left and right ends of the first fixed frame (104); the hydraulic push rod (106) is fixedly mounted on the front and rear ends of the connecting plate (105); the first push rod (107) is fixedly mounted on the lower end of the hydraulic push rod (106); the second fixed frame (108) is fixedly mounted on the lower end of the first push rod (107); the fixed column (109) is fixedly mounted on the lower end of the right end of the second fixed frame (108); and the lead plate (110) is fixedly mounted on the lower end of the fixed column (109).

2. The fixing device for a rat back skin radiation experimental model according to claim 1, characterized in that: The fixing mechanism (2) comprises an irradiation area (201), a plexiglass sheet (202), a magnet (203), an irradiation field (204) and a skin support (205); the irradiation area (201) is fixedly mounted on the upper end of the lead plate (110).

3. The fixing device for a rat back skin radiation experimental model according to claim 2, characterized in that: The organic glass sheet (202) is movably mounted on the lower end of the lead plate (110), and the magnet (203) is fixedly mounted on the left and right ends of the organic glass sheet (202).

4. The fixing device for a rat back skin radiation experimental model according to claim 3, characterized in that: The irradiation field (204) is fixedly arranged in the middle of the organic glass sheet (202), and the skin support (205) is movably installed at the lower end of the organic glass sheet (202).

5. The fixing device for a rat back skin radiation experimental model according to claim 4, characterized in that: The support mechanism (3) comprises an electric push rod (301), a second push rod (302), an irradiator (303) and an irradiation head (304); the electric push rod (301) is fixedly mounted at the middle of the lower end of the ceiling (101).

6. The fixing device for a rat back skin radiation experimental model according to claim 5, characterized in that: The second push rod (302) is fixedly mounted on the lower end of the electric push rod (301), the irradiator (303) is fixedly mounted on the lower end of the second push rod (302), and the irradiation head (304) is fixedly mounted on the lower end of the irradiator (303).

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