Stem cell sample storage device

Abstract

The utility model discloses a stem cell sample storage device, which relates to the technical field of stem cell storage and comprises a storage box, a material taking port, a material taking unit and a sealing plate, the material taking port, the material taking unit and the sealing plate are arranged on the upper surface of the storage box, a rotating unit and a supporting frame are arranged in the storage box, a placing frame is rotatably mounted on the supporting frame, and a placing groove and a positioning groove are arranged on the placing frame. And a fixing unit is arranged in the placing groove. The stem cell test tube storage rack has the beneficial effects that through cooperative work of a second hydraulic cylinder, a second motor, a driving block, a through hole, a first hydraulic cylinder, a suction cup sleeve, a first motor, a screw rod and a sliding block, stem cell test tubes or cryopreservation tubes can be rapidly stored and taken out in the storage box, the whole storage rack does not need to be taken out during storage, damage to other stem cells is avoided, and meanwhile the storage rack is convenient to use. And during storage, workers do not need to directly contact the storage box and the placing frame, so that the workers are effectively prevented from being frostbitten during material taking and placing, and the safety and speed during material taking and placing are improved.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell storage, in particular to a stem cell sample storage device. Background Art

[0002] Simply put, stem cells are a type of cell that has the ability to self-renew and produce at least one type of highly differentiated daughter cells. The definition of stem cells has been revised over the years and defined at different levels. Generally, stem cells are stored in storage boxes, which are generally stored at low temperatures to ensure the shelf life of stem cells.

[0003] After searching, the Chinese patent publication number CN220529117U discloses a space-adjustable stem cell storage device, which mainly adjusts the distance of the fixed frame through bearings and screw rods, thereby adjusting the internal space to facilitate the placement of test tubes.

[0004] By comparing with the existing technologies in related fields, it can be seen that when storing stem cells, liquid nitrogen needs to be placed in the storage box so that the storage box is in the best storage environment for stem cells. When storing stem cell test tubes or cryotubes, the stem cell test tubes or cryotubes are placed on a storage rack, and the staff needs to place the storage rack into the storage box. The entire storage rack needs to be taken out each time, which slows down the storage of stem cells. During the placement, the temperature in the storage box is low, and the staff is at risk of frostbite. Utility Model Content

[0005] The purpose of the utility model is to provide a stem cell sample storage device in order to solve the above problems.

[0006] The utility model achieves the above-mentioned purpose through the following technical solutions:

[0007] A stem cell sample storage device comprises a storage box, and a material taking port, a material taking unit and a sealing plate arranged on the upper surface of the storage box. A rotating unit and a supporting frame are arranged inside the storage box. A placing rack is rotatably mounted on the supporting frame. A placing slot and a positioning slot are arranged on the placing rack. A fixing unit is arranged in the placing slot. According to the prior art, liquid nitrogen is placed in the storage box to maintain an environment suitable for stem cell storage in the storage box. The placing rack is supported by the supporting frame to improve the stability of the placing rack. Stem cell test tubes or cryopreservation tubes are stored by the placing rack and the placing slot. The stored stem cell test tubes or cryopreservation tubes are fixed by the fixing unit. The stem cell test tubes or cryopreservation tubes on the placing rack are driven to rotate by the rotating unit. The material taking unit can take and place stem cell test tubes or cryopreservation tubes of different heights through the material taking port and the positioning slot. The material taking port is sealed by the sealing plate to prevent the internal low temperature loss of the storage box.

[0008] The material taking unit comprises a mounting frame, a displacement assembly is arranged on the mounting frame, a first hydraulic cylinder is arranged on the displacement assembly, the first hydraulic cylinder is located directly above the material taking port, a suction cup sleeve is arranged on the telescopic end of the first hydraulic cylinder, a connecting valve is arranged on the suction cup sleeve, the first hydraulic cylinder is electrically connected to an external controller, the first hydraulic cylinder works by adopting the existing technology, the connecting valve is connected to an external vacuum pumping device, the first hydraulic cylinder drives the suction cup sleeve to enter the storage box through the material taking port, and the stem cell test tube or the cryopreservation tube is placed in the storage box through the suction cup sleeve and the connecting valve, or the stem cell test tube or the cryopreservation tube stored in the storage box is taken out;

[0009] The rotating unit includes a driving component and a through hole. The driving component is installed on the storage box. A driving block is installed on the driving component. The through hole is set at the center of the placement rack. The through hole and the driving block are both triangular. The driving block is slidably connected to the through hole. The driving block is driven into the through hole by the driving component. Since the through hole and the driving block are both triangular, the driving component drives the placement rack to rotate through the driving block, thereby adjusting the position of the stem cell test tube or the cryopreservation tube on the placement rack, which is convenient for taking and placing the stem cell test tube or the cryopreservation tube at different positions on the placement rack.

[0010] Furthermore, the displacement assembly includes a first motor and a screw, the first motor is mounted on a mounting frame, the screw is rotatably mounted on the mounting frame, the screw is fixedly connected to the output shaft of the first motor, a slider is threadedly connected to the screw, the slider is slidably connected to the mounting frame, the slider is connected to the first hydraulic cylinder, the first motor and an external controller are electrically connected, the first motor works using existing technology, and the first hydraulic cylinder is driven to move by the first motor, the screw and the slider, thereby adjusting the position of the first hydraulic cylinder, thereby adjusting the position of the material picking.

[0011] Furthermore, the driving assembly includes a second hydraulic cylinder, which is installed on the storage box. The telescopic end of the second hydraulic cylinder is slidably connected to the storage box. A second motor is installed on the part of the telescopic end of the second hydraulic cylinder located in the storage box. The output shaft of the second motor is connected to the driving block. The second hydraulic cylinder, the second motor and the external controller are electrically connected. The height of the driving block is adjusted by the second hydraulic cylinder, so that stem cell test tubes or cryogenic tubes on racks of different heights can be taken in and out. The second motor drives the rack to rotate through the driving block, so as to facilitate the taking in and out of stem cell test tubes or cryogenic tubes at different positions on the rack.

[0012] Furthermore, the fixing unit includes a storage groove, which is arranged at an equal angle in the placement groove. A spring is installed in the storage groove, and the spring is connected to a top plate. The top plate is slidably connected in the storage groove. The stem cell test tube or cryopreservation tube in the placement groove is clamped and fixed by the spring and the top plate, thereby improving the stability of the stem cell test tube or cryopreservation tube during storage.

[0013] Furthermore, an induction sensor is provided on the inner side of the storage box. The induction sensor and the placement rack have the same height. The induction sensor and the external controller are electrically connected. The induction sensor works using existing technology. The placement rack is positioned by the induction sensor so that the positioning groove on the placement rack can correspond to the induction sensor, thereby completing the resetting of the placement rack and facilitating the removal and placement of materials.

[0014] Furthermore, a temperature sensor is provided on the inner upper surface of the storage box, and the temperature sensor is electrically connected to an external controller. The temperature sensor works by adopting existing technology, and the temperature inside the storage box is monitored by the temperature sensor.

[0015] The beneficial effects compared with the prior art are as follows:

[0016] 1. The placement slots at different positions on the placement racks at different heights are moved to the bottom of the material taking port through the second hydraulic cylinder, the second motor, the driving block and the through hole. The first hydraulic cylinder and the suction cup sleeve take the stem cell test tubes or cryopreservation tubes at different heights in the storage box through the material taking port and the positioning slot. The material taking positions of the first hydraulic cylinder and the suction cup sleeve are adjusted through the first motor, the screw rod and the slider, so that the stem cell test tubes or cryopreservation tubes can be quickly stored and retrieved in the storage box as needed. When storing, there is no need to take out the placement rack as a whole to avoid damage to other stem cells. At the same time, when storing, there is no need for the staff to directly contact the storage box and the placement rack, which effectively avoids frostbite when the staff takes and puts the materials, and improves the safety and speed of taking and putting the materials.

[0017] 2. When the test tubes or cryopreservation tubes containing stem cells are stored, the stem cell test tubes or cryopreservation tubes are clamped and fixed by the storage grooves, springs, and top plates, thereby effectively improving the stability and safety of the stem cell test tubes or cryopreservation tubes during storage. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0019] Figure 1 This is a schematic diagram of the overall structure of a stem cell sample storage device described in the utility model;

[0020] Figure 2 It is a side cross-sectional structural schematic diagram of a stem cell sample storage device according to the utility model;

[0021] Figure 3 The utility model is a stem cell sample storage device Figure 2 The enlarged structural diagram at A in the middle;

[0022] Figure 4 This is a schematic diagram of the structure of a placement rack of a stem cell sample storage device described in the utility model;

[0023] Figure 5 It is a partial cross-sectional structural schematic diagram of a placement rack of a stem cell sample storage device described in the utility model;

[0024] Figure 6 The utility model is a stem cell sample storage device Figure 5 The enlarged structural diagram at B in the middle;

[0025] Figure 7 It is a partial enlarged structural schematic diagram of a stem cell sample storage device described in the utility model;

[0026] Figure 8 The utility model is a schematic diagram of a bottom cross-sectional structure of a stem cell sample storage device as viewed from above.

[0027] The following are the descriptions of the reference numerals:

[0028] 1. Storage box; 2. Material taking port; 3. Material taking unit; 31. Mounting frame; 32. First motor; 33. Screw; 34. Slider; 35. First hydraulic cylinder; 36. Suction cup sleeve; 37. Connecting valve; 4. Fixing unit; 41. Storage slot; 42. Spring; 43. Top plate; 5. Rotating unit; 51. Second hydraulic cylinder; 52. Second motor; 53. Driving block; 54. Through hole; 6. Closing plate; 7. Placement frame; 8. Placement slot; 9. Positioning slot; 10. Induction sensor; 11. Support frame; 12. Temperature sensor. DETAILED DESCRIPTION

[0029] like Figure 1-Figure 8 As shown, a stem cell sample storage device comprises a storage box 1, and a material taking port 2, a material taking unit 3 and a sealing plate 6 arranged on the upper surface of the storage box. A rotating unit 5 and a supporting frame 11 are arranged inside the storage box 1. A placing frame 7 is rotatably mounted on the supporting frame 11. The placing frame 7 is provided with a placing groove 8 and a positioning groove 9. A fixing unit 4 is arranged in the placing groove 8. According to the prior art, liquid nitrogen is placed in the storage box 1, so as to maintain an environment suitable for stem cell storage in the storage box 1. Figure 1-Figure 5As shown, the placement rack 7 is supported by a support frame 11, and the support frame 11 adopts a magnetic seat to prevent the placement rack 7 from rotating during the placement process, thereby improving the stability of the placement rack 7, and storing the stem cell test tubes or cryopreservation tubes through the placement rack 7 and the placement slot 8. The stored stem cell test tubes or cryopreservation tubes are fixed by the fixing unit 4, and the stem cell test tubes or cryopreservation tubes on the placement rack 7 are driven to rotate by the rotating unit 5. The material taking unit 3 can take and place stem cell test tubes or cryopreservation tubes of different heights through the material taking port 2 and the positioning slot 9, and the material taking port 2 is closed by the sealing plate 6 to prevent the internal low temperature loss of the storage box 1;

[0030] The material taking unit 3 includes a mounting frame 31, a displacement assembly is arranged on the mounting frame 31, a first hydraulic cylinder 35 is arranged on the displacement assembly, the first hydraulic cylinder 35 is located directly above the material taking port 2, a suction cup sleeve 36 is arranged on the telescopic end of the first hydraulic cylinder 35, a connecting valve 37 is arranged on the suction cup sleeve 36, the first hydraulic cylinder 35 is electrically connected to an external controller, the first hydraulic cylinder 35 works by adopting the existing technology, and the connecting valve 37 is connected to an external vacuum device, such as Figure 1 , Figure 2 , Figure 4 , Figure 5 , Figure 7 As shown, the displacement assembly drives the first hydraulic cylinder 35 to move, so that the suction cup sleeve 36 corresponds to the placement slot 8 on the placement rack 7, and the first hydraulic cylinder 35 drives the suction cup sleeve 36 to enter the storage box 1 through the material taking port 2, and the stem cell test tube or cryopreservation tube is placed in the storage box 1 through the suction cup sleeve 36 and the connecting valve 37, or the stem cell test tube or cryopreservation tube stored in the storage box 1 is taken out, and the stem cell test tube or cryopreservation tube is stored and retrieved at a fixed point. When storing, there is no need to take out the placement rack 7 as a whole, so as to avoid damage to other stem cells, and there is no need for the staff to directly contact the storage box 1 and the placement rack 7, so as to effectively avoid frostbite when the staff takes and places materials, and improve the safety and speed of taking and placing materials;

[0031] The rotating unit 5 includes a driving assembly and a through hole 54. The driving assembly is mounted on the storage box 1. A driving block 53 is mounted on the driving assembly. The through hole 54 is arranged at the center of the placement frame 7. Both the through hole 54 and the driving block 53 are triangular. The driving block 53 is slidably connected to the through hole 54. Figure 2-Figure 5 , Figure 8 As shown, the driving block 53 is driven by the driving assembly to enter the through hole 54. Since the through hole 54 and the driving block 53 are both triangular, the driving assembly drives the placement rack 7 to rotate through the driving block 53, thereby adjusting the position of the stem cell test tube or the cryopreservation tube on the placement rack 7, making it convenient to take and place the stem cell test tube or the cryopreservation tube at different positions on the placement rack 7.

[0032] The displacement assembly includes a first motor 32 and a screw 33. The first motor 32 is mounted on the mounting frame 31. The screw 33 is rotatably mounted on the mounting frame 31. The screw 33 is fixedly connected to the output shaft of the first motor 32. A slider 34 is threadedly connected to the screw 33. The slider 34 is slidably connected to the mounting frame 31. The slider 34 is connected to the first hydraulic cylinder 35. The first motor 32 is electrically connected to the external controller. The first motor 32 works using existing technologies, such as Figure 1 , Figure 2 As shown, the screw 33 is driven to rotate by the first motor 32, and the screw 33 drives the first hydraulic cylinder 35 to move through the slider 34, so as to adjust the position of the first hydraulic cylinder 35, thereby adjusting the material picking position, so as to facilitate picking and placing materials at different positions on the placement rack 7.

[0033] The driving assembly includes a second hydraulic cylinder 51, which is mounted on the storage box 1. The telescopic end of the second hydraulic cylinder 51 is slidably connected to the storage box 1. A second motor 52 is mounted on the telescopic end of the second hydraulic cylinder 51 located inside the storage box 1. The output shaft of the second motor 52 is connected to the driving block 53. The second hydraulic cylinder 51 and the second motor 52 are electrically connected to an external controller. The second hydraulic cylinder 51 and the second motor 52 work using existing technologies, such as Figure 1-Figure 3 As shown, the second hydraulic cylinder 51 drives the driving block 53 to move through the second motor 52, thereby adjusting the height of the driving block 53, so that the driving block 53 enters the through hole 54 at different heights, so that the stem cell test tubes or cryotubes on the placement rack 7 at different heights can be taken and placed, and then the driving block 53 is driven to rotate by the second motor 52, and the placement rack 7 is driven to rotate by the driving block 53. Through the rotation of the placement rack 7, the stem cell test tubes or cryotubes stored at different positions on the placement rack 7 are moved to just below the material removal port 2, thereby facilitating the taking and placing of stem cell test tubes or cryotubes at different positions on the placement rack 7.

[0034] The fixing unit 4 includes a receiving groove 41, which is arranged at an equal angle in the placement groove 8. A spring 42 is installed in the receiving groove 41, and the spring 42 is connected to a top plate 43. The top plate 43 is slidably connected in the receiving groove 41. Figure 6 As shown, after the stem cell test tube or the cryotube is placed in the placement groove 8, the stem cell test tube or the cryotube squeezes the spring 42 through the top plate 43. Under the elastic force of the spring 42, the spring 42 clamps and fixes the stem cell test tube or the cryotube in the placement groove 8 through the top plate 43, thereby improving the stability of the stem cell test tube or the cryotube during storage.

[0035] An inductive sensor 10 is provided on the inner side of the storage box 1. The inductive sensor 10 is at the same height as the placement rack 7. The inductive sensor 10 is electrically connected to an external controller. The inductive sensor 10 works using existing technology, such as Figure 2 , Figure 8 As shown, when the placement rack 7 rotates, the placement rack 7 is positioned by the inductive sensor 10. When the positioning groove 9 on the placement rack 7 can correspond to the inductive sensor 10, the placement rack 7 is reset and positioned, which is convenient for marking the stem cells stored on the placement rack 7 and for taking and placing the materials.

[0036] A temperature sensor 12 is provided on the inner upper surface of the storage box 1. The temperature sensor 12 is electrically connected to the external controller. The temperature sensor 12 works by using existing technology, such as Figure 2 As shown, the temperature in the storage box 1 is monitored by the temperature sensor 12, so that the temperature in the storage box 1 can be controlled in time to prevent the temperature change in the storage box 1 from affecting the normal storage of stem cells.

[0037] Working principle: When storing stem cell test tubes or cryopreserved tubes, Figure 1 As shown, the material taking port 2 is opened by the sealing plate 6. Figure 1 , Figure 2 As shown, the end of the test tube or cryopreservation tube containing stem cells is placed in the suction cup sleeve 36, so that the stem cell test tube or cryopreservation tube is adsorbed in the suction cup sleeve 36; according to the position where the stem cell test tube or cryopreservation tube needs to be placed, as shown in FIG. Figure 1 , Figure 2 As shown, the first motor 32 drives the screw 33 to rotate, and the screw 33 drives the first hydraulic cylinder 35 to move through the slider 34, so as to move the stem cell test tube or the cryopreservation tube to the top of the position where it needs to be placed;

[0038] like Figure 1-Figure 3 As shown, the second hydraulic cylinder 51 drives the driving block 53 to move through the second motor 52, as shown in FIG. Figure 2-Figure 5 , Figure 8 As shown, the driving block 53 enters into the through hole 54 on the placement rack 7 of the corresponding height, and the second motor 52 drives the driving block 53 to rotate, and the placement rack 7 is driven to rotate by the driving block 53, so that the idle placement slot 8 on the placement rack 7 moves to the right below the material taking port 2;

[0039] like Figure 1 , Figure 2 , Figure 4 , Figure 5 , Figure 7 As shown, the first hydraulic cylinder 35 drives the suction cup sleeve 36 to enter the storage box 1 through the material taking port 2, and passes through the positioning groove 9, so that the stem cell test tube or the cryopreservation tube enters the placement groove 8;

[0040] like Figure 6As shown, after the stem cell test tube or cryotube is placed in the placement slot 8, the stem cell test tube or cryotube squeezes the spring 42 through the top plate 43. Under the elastic force of the spring 42, the spring 42 clamps and fixes the stem cell test tube or cryotube in the placement slot 8 through the top plate 43;

[0041] After the stem cell tube or cryopreservation tube is placed, Figure 2-Figure 5 , Figure 8 As shown, the second motor 52 drives the driving block 53 to rotate, and the driving block 53 drives the placement rack 7 to rotate, so that the positioning groove 9 on the placement rack 7 rotates to the position corresponding to the induction sensor 10. At this time, the placement rack 7 is reset;

[0042] After the stem cell tube or cryopreservation tube is placed, Figure 1 As shown, the material taking port 2 is sealed by a sealing plate 6, and liquid nitrogen is placed in the storage box 1 to ensure that the storage box 1 is at the optimal storage temperature for stem cells. Figure 2 As shown, the temperature in the storage box 1 is monitored by the temperature sensor 12, so that the temperature in the storage box 1 can be controlled in time to prevent the temperature change in the storage box 1 from affecting the normal storage of stem cells;

[0043] When taking out the materials, the same operation as above is adopted to take out the stored stem cells through the first hydraulic cylinder 35 and the suction cup sleeve 36, so that the staff does not need to directly contact the storage box 1 and the placement rack 7 when taking out and placing the stem cells, which effectively avoids frostbite of the staff when taking out and placing the materials, and improves the safety and speed of taking out and placing the materials.

[0044] The above shows and describes the basic principle, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments, and the above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements fall within the scope of the utility model to be protected.

Claims

1. A stem cell sample storage device, comprising a storage box (1), and a material taking port (2), a material taking unit (3) and a sealing plate (6) arranged on the upper surface of the storage box, characterized in that: The storage box (1) is provided with a rotating unit (5) and a supporting frame (11) inside, a placing frame (7) is rotatably mounted on the supporting frame (11), a placing groove (8) and a positioning groove (9) are provided on the placing frame (7), and a fixing unit (4) is provided in the placing groove (8); The material taking unit (3) comprises a mounting frame (31), a displacement assembly is arranged on the mounting frame (31), a first hydraulic cylinder (35) is installed on the displacement assembly, the first hydraulic cylinder (35) is located directly above the material taking port (2), a suction cup sleeve (36) is installed on the telescopic end of the first hydraulic cylinder (35), and a connecting valve (37) is arranged on the suction cup sleeve (36); The rotating unit (5) comprises a driving assembly and a through hole (54); the driving assembly is mounted on the storage box (1); a driving block (53) is mounted on the driving assembly; the through hole (54) is arranged at the center of the placement rack (7); the through hole (54) and the driving block (53) are both triangular in shape; and the driving block (53) is slidably connected to the through hole (54).

2. A stem cell sample storage device according to claim 1, characterized in that: The displacement assembly comprises a first motor (32) and a screw rod (33), wherein the first motor (32) is mounted on the mounting frame (31), the screw rod (33) is rotatably mounted on the mounting frame (31), the screw rod (33) is fixedly connected to an output shaft of the first motor (32), a slider (34) is threadedly connected to the screw rod (33), the slider (34) is slidably connected to the mounting frame (31), and the slider (34) is connected to the first hydraulic cylinder (35).

3. A stem cell sample storage device according to claim 1, characterized in that: The driving assembly comprises a second hydraulic cylinder (51), the second hydraulic cylinder (51) is mounted on the storage box (1), the telescopic end of the second hydraulic cylinder (51) is slidably connected to the storage box (1), a second motor (52) is mounted on the portion of the telescopic end of the second hydraulic cylinder (51) located inside the storage box (1), and the output shaft of the second motor (52) is connected to the driving block (53).

4. A stem cell sample storage device according to claim 1, characterized in that: The fixing unit (4) comprises a receiving groove (41), the receiving groove (41) being arranged at an equal angle in the placement groove (8), a spring (42) being installed in the receiving groove (41), the spring (42) being connected to a top plate (43), and the top plate (43) being slidably connected in the receiving groove (41).

5. A stem cell sample storage device according to claim 1, characterized in that: An inductive sensor (10) is provided on the inner side of the storage box (1), and the inductive sensor (10) and the placement rack (7) are at the same height.

6. A stem cell sample storage device according to claim 1, characterized in that: A temperature sensor (12) is provided on the inner upper surface of the storage box (1).

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