Solid-liquid separation device for pharmaceutical analysis
By designing a solid-liquid separation device that combines extrusion and negative pressure suction, the problem of the inability of traditional devices to completely separate drug solids and liquids and the difficulty in removing solid drugs is solved, achieving more efficient separation and more convenient operation.
Patent Information
- Application Number
- CN202420309789.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-20
- Publication Date
- 2025-01-21
- Estimated Expiration
- 2034-02-20
AI Technical Summary
Traditional solid-liquid separation devices for drug analysis cannot completely separate solid-liquid from drugs, and it is difficult to remove solid-liquid drugs, resulting in high operating time and labor intensity.
A solid-liquid separation device including a separation cylinder, an extrusion piece, a filter plate, a separation funnel and a negative pressure machine is designed. Through the dual effects of extrusion and negative pressure suction, complete solid-liquid separation of the drug is achieved, and during the separation It is convenient to take out the solid medicine after completion.
It achieves thoroughness and rapidity of solid-liquid separation of drugs, while simplifying the process of taking out solid drugs and reducing operation difficulty and time.
Smart Images
Figure CN222368502U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of solid-liquid separation, and in particular relates to a solid-liquid separation device for drug analysis. Background Art
[0002] The development of science and technology has led to the rise of the pharmaceutical industry. There are many ways to make medicines, one of which is to separate the solids and liquids in the medicine. One of the main functions of solid-liquid separation is to analyze the separated drugs to detect the composition of the drugs.
[0003] Traditional solid-liquid separation devices for drug analysis usually only use a sieve plate to leak out the liquid and leave the solid on the filter net to achieve the purpose of solid-liquid separation. This solid-liquid separation method cannot completely separate the drugs from the solid and liquid. Moreover, after the solid-liquid separation is completed, the liquid can be collected in a centralized manner in the traditional solid-liquid separation device for drug analysis, while the solid drugs in the container are located at the bottom of the container, so the removal process is relatively difficult and a large amount of drug residues are easily left in it, resulting in a waste of time and effort in the process of removing the solid drugs after the solid separation is completed. Utility Model Content
[0004] The utility model aims to provide a solid-liquid separation device for drug analysis to solve the above problems and achieve the purpose of thoroughly separating the solid and liquid in the drug and conveniently taking out the remaining solid drug after the solid-liquid separation is completed.
[0005] To achieve the above object, the utility model provides the following solution: a solid-liquid separation device for drug analysis, comprising:
[0006] frame;
[0007] A separation cylinder, wherein openings are respectively provided at the upper and lower ends of the separation cylinder, an extrusion piece is provided at the top of the frame, and the extrusion piece corresponds to the interior of the separation cylinder through the opening at the top of the separation cylinder, a separation funnel is provided at the bottom of the separation cylinder, and the large-diameter end of the separation funnel is adapted to the bottom opening of the separation cylinder, a filter plate is provided in the separation funnel, and two groups of fixing frames are fixedly connected to the side wall of the separation cylinder, the two groups of fixing frames are symmetrically arranged about the axis of the separation cylinder, and a bottom opening and closing piece is provided between the two groups of fixing frames and the separation funnel;
[0008] A liquid storage tank is fixedly connected to the bottom of the frame, the top of the liquid storage tank is connected to the small diameter end of the separation funnel, and a negative pressure machine is fixedly connected to the frame, and the negative pressure machine is connected to the interior of the liquid storage tank.
[0009] Preferably, a rotating shaft is horizontally fixedly connected to the side walls of the two fixed frames, the axes of the two rotating shafts coincide, the two groups of rotating shafts are rotatably connected to the side walls of the frame, a second motor is fixedly connected to the side walls of the frame, and the output shaft of the second motor is coaxially fixedly connected to one of the rotating shafts.
[0010] Preferably, the extrusion member comprises a cylinder vertically fixedly connected to the top of the frame, and a pressure plate is horizontally fixedly connected to the bottom of the cylinder, and the pressure plate corresponds to the interior of the separation cylinder.
[0011] Preferably, the bottom opening and closing member includes a telescopic rod vertically slidably connected to the fixed frame, the bottom of the telescopic rod is fixedly connected to the separation funnel via a connecting plate, a threaded hole is provided on the top of the telescopic rod, a first motor is fixedly connected to the top of the fixed frame, an output shaft of the first motor is coaxially fixedly connected to one end of a screw rod, and the screw rod is transmission-connected to the telescopic rod via the threaded hole.
[0012] Preferably, an annular boss is fixedly connected to the edge of the large diameter end of the separation funnel, and an annular groove is formed at the bottom of the separation cylinder, and the annular boss is matched with the annular groove.
[0013] Preferably, gauze is placed on the top of the filter plate.
[0014] Preferably, the bottom of the separation funnel is connected to a connecting pipe, the top of the liquid storage tank is connected to one end of a connecting hose, and the other end of the connecting hose is detachably connected to the connecting pipe.
[0015] Compared with the prior art, the utility model has the following advantages and technical effects: the main function of the separation cylinder is to hold the solid-liquid mixed medicine; the main function of the extruder is to squeeze the medicine in the separation cylinder downward to separate the liquid by squeezing; the main function of the filter plate is to isolate the solid medicine and allow the liquid to enter the separation funnel; the main function of the bottom opening and closing part is to maintain the connection state between the separation funnel and the bottom of the separation cylinder before the solid-liquid separation is completed, and to separate the separation funnel from the bottom of the separation cylinder after the separation is completed, so as to facilitate the cleaning of the remaining solid medicine; the main function of the negative pressure machine is to put the liquid storage tank and the separation funnel in a negative pressure state during the separation process to accelerate the dripping of the liquid. On the whole, the utility model makes the solid-liquid separation of the medicine more thorough and rapid through the dual functions of squeezing and negative pressure suction. At the same time, the remaining solid medicine can be quickly taken out after the solid-liquid separation is completed, reducing the difficulty of operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0017] Figure 1 It is a schematic diagram of the separation device of the utility model;
[0018] Figure 2 It is a left side cross-sectional view of the separation device of the utility model;
[0019] Figure 3 It is a cross-sectional schematic diagram of the separation cylinder, the fixing frame and the separation funnel of the utility model;
[0020] Figure 4 for Figure 3 A partial enlarged view in FIG.
[0021] Among them, 1. frame; 2. separation cylinder; 3. fixing frame; 4. first motor; 5. pressure plate; 6. cylinder; 7. separation funnel; 8. liquid storage tank; 9. negative pressure machine; 10. second motor; 11. telescopic rod; 12. screw rod; 13. threaded hole; 14. connecting plate; 15. filter plate; 16. gauze; 17. annular boss; 18. annular groove; 19. connecting hose; 20. connecting pipe; 21. negative pressure pipe. DETAILED DESCRIPTION
[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0023] In order to make the above-mentioned purposes, features and advantages of the present invention more obvious and easy to understand, the present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.
[0024] Reference Figure 1-Figure 4 The utility model provides a solid-liquid separation device for drug analysis, comprising:
[0025] Frame 1;
[0026] A separation cylinder 2, with openings respectively provided at the upper and lower ends of the separation cylinder 2, an extrusion piece provided at the top of the frame 1, the extrusion piece corresponding to the inside of the separation cylinder 2 through the opening at the top of the separation cylinder 2, a separation funnel 7 provided at the bottom of the separation cylinder 2, the large diameter end of the separation funnel 7 adapted to the bottom opening of the separation cylinder 2, a filter plate 15 provided in the separation funnel 7, two sets of fixing frames 3 fixedly connected to the side wall of the separation cylinder 2, the two sets of fixing frames 3 symmetrically arranged about the axis of the separation cylinder 2, a bottom opening and closing piece provided between the two sets of fixing frames 3 and the separation funnel 7;
[0027] The liquid storage tank 8 is fixedly connected to the bottom of the frame 1 , the top of the liquid storage tank 8 is connected to the small diameter end of the separation funnel 7 , and a negative pressure machine 9 is fixedly connected to the frame 1 , and the negative pressure machine 9 is connected to the inside of the liquid storage tank 8 .
[0028] The main function of the separation cylinder 2 is to hold the solid-liquid mixed medicine; the main function of the extruder is to squeeze the medicine in the separation cylinder 2 downwards, and separate the liquid by squeezing; the main function of the filter plate 15 is to isolate the solid medicine and allow the liquid to enter the separation funnel 7; the main function of the bottom opening and closing member is to maintain the connection between the separation funnel 7 and the bottom of the separation cylinder 2 before the solid-liquid separation is completed, and to separate the separation funnel 7 from the bottom of the separation cylinder 2 after the separation is completed, so as to facilitate the cleaning of the remaining solid medicine; the main function of the negative pressure machine 9 is to put the liquid storage tank 8 and the separation funnel 7 in a negative pressure state during the separation process to accelerate the dripping of the liquid. On the whole, the utility model makes the solid-liquid separation of the medicine more thorough and rapid through the dual functions of squeezing and negative pressure suction. At the same time, the remaining solid medicine can be quickly taken out after the solid-liquid separation is completed, reducing the difficulty of operation.
[0029] According to a further optimization scheme, the negative pressure machine 9 is connected to the liquid storage tank 8 via a negative pressure pipe 21 , and the negative pressure pipe 21 is connected to the upper part of the side wall of the liquid storage tank 8 .
[0030] like Figure 1 As shown, the negative pressure pipe 21 is located at the upper part of the side wall of the liquid storage tank 8, which can prevent the liquid in the liquid storage tank 8 from being sucked into the negative pressure machine 9.
[0031] A further optimized solution is that the side walls of the two fixed frames 3 are horizontally fixedly connected with rotating shafts, the axes of the two rotating shafts coincide, the two sets of rotating shafts are rotatably connected to the side walls of the frame 1, and the side walls of the frame 1 are fixedly connected with a second motor 10, and the output shaft of the second motor 10 is coaxially fixedly connected with a rotating shaft.
[0032] like Figure 1 and Figure 2As shown, after the solid-liquid separation is completed, by controlling the rotation of the second motor 10, the separation cylinder 2 can be deflected by driving the fixing frame 3, so that the separation funnel 7 deviates from the top of the liquid storage tank 8, leaving enough operating space for the subsequent cleaning of solid drugs. Then, the separation funnel 7 is separated from the bottom of the separation cylinder 2 by the bottom opening and closing member, and the operator can directly remove the drugs from the bottom opening of the separation cylinder 2, reducing the difficulty of operation and labor intensity.
[0033] According to a further optimized solution, the extrusion member includes a cylinder 6 vertically fixedly connected to the top of the frame 1 , and a pressure plate 5 is horizontally fixedly connected to the bottom of the cylinder 6 , and the pressure plate 5 corresponds to the interior of the separation cylinder 2 .
[0034] like Figure 1 As shown, the cylinder 6 is connected to an external high-pressure gas supply device, so that the cylinder 6 can drive the pressing plate 5 to press down and lift. When the separation cylinder 2 is in a vertical state, the medicine to be separated into solid and liquid is poured from the top opening of the separation cylinder 2. After that, the cylinder 6 is controlled to extend, so that the pressing plate 5 presses down from the top of the separation cylinder 2, squeezes the medicine in the separation cylinder 2, and forces the liquid to pass through the filter plate 15 into the separation funnel 7, and finally enters the liquid storage tank 8 for collection.
[0035] A further optimized solution is that the bottom opening and closing part includes a telescopic rod 11 vertically slidably connected to the fixed frame 3, the bottom of the telescopic rod 11 is fixedly connected to the separation funnel 7 through a connecting plate 14, a threaded hole 13 is provided on the top of the telescopic rod 11, a first motor 4 is fixedly connected to the top of the fixed frame 3, and one end of the screw rod 12 is coaxially fixedly connected to the output shaft of the first motor 4, and the screw rod 12 is transmission-connected to the telescopic rod 11 through the threaded hole 13.
[0036] like Figure 3 As shown, when the separation funnel 7 needs to be buckled with the bottom of the separation cylinder 2, the first motor 4 is controlled to rotate, and the first motor 4 drives the screw rod 12 to rotate, and the screw rod 12 and the threaded hole 13 drive the telescopic rod 11 to be retracted into the fixing frame 3 through the threaded transmission, thereby driving the separation funnel 7 to move toward the separation cylinder 2 through the connecting plate 14 until it is buckled with the bottom opening of the separation cylinder 2. When the separation funnel 7 needs to be opened, the first motor 4 is controlled to reverse.
[0037] According to a further optimized solution, an annular boss 17 is fixedly connected to the edge of the large diameter end of the separation funnel 7 , an annular groove 18 is provided at the bottom of the separation cylinder 2 , and the annular boss 17 is matched with the annular groove 18 .
[0038] like Figure 4 As shown, after the separation funnel 7 is buckled with the separation cylinder 2, the annular boss 17 is embedded in the annular groove 18, which can improve the sealing between the separation funnel 7 and the separation cylinder 2 and prevent liquid from leaking from the connection during the separation process.
[0039] According to a further optimized solution, a gauze 16 is placed on the top of the filter plate 15 .
[0040] like Figure 4 As shown, the gauze 16 can improve the separation effect and make the solid matter in the separated liquid less. When the operator lays the gauze 16, the edge of the gauze can cover the annular boss 17. When the separation funnel 7 and the separation cylinder 2 are buckled, the gauze 16 can be clamped between the annular boss 17 and the annular groove 18, which plays the purpose of preventing the gauze 16 from moving during the solid-liquid separation process.
[0041] According to a further optimized solution, the bottom of the separation funnel 7 is connected to a connecting pipe 20 , the top of the liquid storage tank 8 is connected to one end of a connecting hose 19 , and the other end of the connecting hose 19 is detachably connected to the connecting pipe 20 .
[0042] like Figure 1 As shown, during the solid-liquid separation process, the separation cylinder 2 is in a vertical state, the connecting hose 19 is connected to the connecting pipe 20, and the separated liquid enters the liquid storage tank 8 through the separation funnel 7 and the connecting hose 19. When the object medicine in the separation cylinder 2 needs to be processed, the connecting hose 19 can be pulled off from the connecting pipe 20 to facilitate the deflection of the separation cylinder 2 in the frame 1.
[0043] As a further optimization scheme, the bottom of the side wall of the liquid storage tank 8 is connected to a liquid outlet pipe (not shown in the figure) with a valve, and the liquid outlet pipe can lead out the liquid in the liquid storage tank 8.
[0044] A further optimized solution further includes a controller (not shown in the figure), which is electrically connected to the first motor 4, the second motor 10, the cylinder 6 and the negative pressure machine 9.
[0045] The working process of this embodiment is as follows: in the initial state, the separation cylinder 2 is in a vertical state, and the cylinder 6 is in a retracted state. The operator controls the first motor 4 to rotate through the controller, so that the separation funnel 7 descends, and the gauze 16 is laid on the filter plate 15 and covers the annular boss 17. After that, the first motor 4 is controlled to reverse, so that the separation funnel 7 is buckled with the separation cylinder 2, and then the medicine to be separated is poured into the separation cylinder 2. After that, the negative pressure machine 9 is controlled to work through the controller, and the cylinder 6 is controlled to extend at the same time. Under the extrusion of the pressing plate 5 and the negative pressure generated by the negative pressure machine 9, the liquid in the separation cylinder 2 enters the liquid storage tank 8 through the separation funnel 7 and the connecting hose 19 for collection.
[0046] After the solid-liquid separation is completed, the connection between the connecting hose 19 and the connecting pipe 20 is disconnected, the second motor 10 is controlled to deflect the separation cylinder 2, and the first motor 4 is controlled to rotate to move the separation funnel 7 away from the bottom of the separation cylinder 2. The solid medicine in the separation cylinder 2 will automatically fall through the bottom opening, and the medicine adhered to the side wall of the separation cylinder 2 can also be conveniently pushed out from the top opening of the separation cylinder 2 to the bottom opening. The liquid in the liquid storage tank 8 can be drawn out from the liquid outlet pipe.
[0047] In the description of the present invention, it should be understood that the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside" and "outside" etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present invention.
[0048] The embodiments described above are only descriptions of the preferred methods of the present invention, and are not intended to limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by ordinary technicians in this field should fall within the protection scope determined by the claims of the present invention.
Claims
1. A solid-liquid separation device for drug analysis, characterized in that: include: Framework (1); A separation cylinder (2), wherein the upper and lower ends of the separation cylinder (2) are respectively provided with openings, an extrusion piece is arranged at the top of the frame (1), and the extrusion piece corresponds to the interior of the separation cylinder (2) through the opening at the top of the separation cylinder (2), a separation funnel (7) is arranged at the bottom of the separation cylinder (2), the large diameter end of the separation funnel (7) is adapted to the bottom opening of the separation cylinder (2), a filter plate (15) is arranged in the separation funnel (7), two groups of fixing frames (3) are fixedly connected to the side wall of the separation cylinder (2), the two groups of fixing frames (3) are symmetrically arranged about the axis of the separation cylinder (2), and a bottom opening and closing piece is arranged between the two groups of fixing frames (3) and the separation funnel (7); A liquid storage tank (8), the liquid storage tank (8) is fixedly connected to the bottom of the frame (1), the top of the liquid storage tank (8) is connected to the small diameter end of the separation funnel (7), and a negative pressure machine (9) is fixedly connected to the frame (1), and the negative pressure machine (9) is connected to the inside of the liquid storage tank (8).
2. A solid-liquid separation device for drug analysis according to claim 1, characterized in that: A rotating shaft is respectively fixedly connected horizontally to the side walls of the two fixed frames (3), the axes of the two rotating shafts coincide with each other, and the two groups of rotating shafts are respectively rotatably connected to the side walls of the frame (1). A second motor (10) is fixedly connected to the side walls of the frame (1), and the output shaft of the second motor (10) is fixedly connected to one of the rotating shafts coaxially.
3. The solid-liquid separation device for drug analysis according to claim 1, characterized in that: The extrusion member comprises a cylinder (6) vertically fixedly connected to the top of the frame (1), and a pressure plate (5) is horizontally fixedly connected to the bottom of the cylinder (6), and the pressure plate (5) corresponds to the interior of the separation cylinder (2).
4. The solid-liquid separation device for drug analysis according to claim 1, characterized in that: The bottom opening and closing member comprises a telescopic rod (11) vertically slidably connected to the fixing frame (3); the bottom of the telescopic rod (11) is fixedly connected to the separation funnel (7) via a connecting plate (14); a threaded hole (13) is provided at the top of the telescopic rod (11); a first motor (4) is fixedly connected to the top of the fixing frame (3); an output shaft of the first motor (4) is coaxially fixedly connected to one end of a screw rod (12); and the screw rod (12) is transmission-connected to the telescopic rod (11) via the threaded hole (13).
5. The solid-liquid separation device for drug analysis according to claim 1, characterized in that: An annular boss (17) is fixedly connected to the edge of the large diameter end of the separation funnel (7), and an annular groove (18) is provided at the bottom of the separation cylinder (2), and the annular boss (17) is matched with the annular groove (18).
6. The solid-liquid separation device for drug analysis according to claim 1, characterized in that: Gauze (16) is placed on the top of the filter plate (15).
7. The solid-liquid separation device for drug analysis according to claim 1, characterized in that: The bottom of the separation funnel (7) is connected to a connecting pipe (20), and the top of the liquid storage tank (8) is connected to one end of a connecting hose (19), and the other end of the connecting hose (19) is detachably connected to the connecting pipe (20).