Crystal form medicine production and preparation device

By designing a preparation device for drug production, using technical means such as electric push rods and stirring leaves, the problem of uneven dissolution of drug raw materials is solved, and a more efficient and uniform drug dissolution process is achieved, and product quality and stability are improved. sex.

CN222427792UActive Publication Date: 2025-02-07WUHAN XINLIANDA BIOLOGY
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Patent Information

Application Number
CN202421234923.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-31
Publication Date
2025-02-07
Estimated Expiration
2034-05-31

AI Technical Summary

Technical Problem

In the prior art, the drug raw materials have a limited contact area with the solvent during the dissolution process, resulting in uneven dissolution, and some drug raw materials are prone to accumulate, resulting in aggregation and precipitation.

Method used

A crystalline drug production and preparation device is designed, including a first dissolution barrel and a second dissolution barrel. The second dissolution barrel is shaken by an electric push rod, increasing the contact area between the drug raw material and the solvent, and accelerating the molecule through the second stirring leaf. Collision and mix to ensure even dissolution.

Benefits of technology

Effectively reduce the aggregation and precipitation of drug raw materials during dissolution, improve dissolution efficiency and speed, ensure full mixing and reaction of drug raw materials, and improve product quality and stability.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the technical field of medicine production, and particularly relates to a crystal form medicine production and preparation device which comprises a first dissolving barrel. The top of the first dissolving barrel is fixedly connected with a feeding pipe; two fixing frames are fixedly connected to the top of the first dissolving barrel; the two fixing frames are oppositely arranged; motors are fixedly connected to the end parts of the two fixing frames; the output end of the motor is fixedly connected with a first rotating rod; the middle of the first rotating rod penetrates through the top of the first dissolving barrel; a plurality of groups of first stirring blades are fixedly connected to the middle part of the first rotating rod; a plurality of groups of springs are fixedly connected to the bottom of the first dissolving barrel; a plurality of groups of springs are fixedly connected to the interior of the first dissolving barrel; the end parts of the plurality of groups of springs are fixedly connected with a second dissolving barrel; two electric push rods are fixedly connected to the side wall of the first dissolving barrel; the second dissolving barrel is shaken through the electric push rod, so that the medicine raw materials can be more uniformly distributed in the solvent, and the medicine raw materials can be effectively and fully mixed and reacted in the dissolving process.
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Description

Technical Field

[0001] The utility model belongs to the technical field of drug production, in particular to a device for producing and preparing crystal drugs. Background Art

[0002] Crystalline drugs refer to drugs in a crystalline form with a regular geometric shape and fixed chemical composition in the solid state. Control of drug crystal form is very important in the pharmaceutical industry, as it affects the quality and efficacy of drugs, as well as the health and safety of patients.

[0003] In the prior art, the production and preparation process of crystalline drugs requires adding the drug raw materials to a selected solvent, stirring the drug raw materials to completely dissolve them, and inducing the drug to form a specific crystalline form under certain conditions by adding seed crystals during the dissolution process.

[0004] During the dissolution process of the drug raw materials, the contact area between the drug raw materials and the solvent is limited, and some drug raw materials tend to accumulate on one side of the container, causing the problem of uneven dissolution of the drug raw materials. Utility Model Content

[0005] In order to make up for the deficiencies of the prior art, at least one technical problem raised in the background technology is solved.

[0006] The technical solution adopted by the present invention to solve its technical problems is as follows: a crystalline drug production and preparation device described in the present invention comprises a first dissolving barrel; a feeding pipe is fixedly connected to the top of the first dissolving barrel; two fixing frames are fixedly connected to the top of the first dissolving barrel; the two fixing frames are arranged oppositely; the ends of the two fixing frames are fixedly connected to a motor; the output end of the motor is fixedly connected to a first rotating rod; the middle part of the first rotating rod passes through the top of the first dissolving barrel; the middle part of the first rotating rod is fixedly connected to multiple groups of first stirring blades; the bottom of the first dissolving barrel is fixedly connected to multiple groups of springs; multiple groups of springs are fixed inside the first dissolving barrel; the ends of multiple groups of springs are fixedly connected to the second dissolving barrel; two electric push rods are fixedly connected to the side wall of the first dissolving barrel; the two electric push rods are arranged oppositely; the ends of the electric push rods are fixedly connected to the side wall of the second dissolving barrel; wherein the ends of the two first stirring blades are fixedly connected to the first fixing rod; the end of the first fixing rod is fixedly connected to the first magnet; the middle part of the first stirring blade is fixedly connected to the first support rod; The end of the first support rod is fixedly connected to a rotating shaft; a second rotating rod is fixedly connected to the two opposite ends of the rotating shaft; multiple groups of second stirring blades are fixedly connected to the middle of the second rotating rod; multiple groups of second stirring blades are equidistantly distributed in the middle of the second rotating rod; a second magnet is fixedly connected to the side wall of the second stirring blade; the first magnet and the second magnet repel each other when they are close to each other; the second dissolving barrel is shaken by an electric push rod, so that the drug raw materials can be more evenly distributed in the solvent, effectively reducing the aggregation and precipitation of the drug raw materials when dissolving inside the second dissolving barrel, effectively increasing the contact area between the drug raw materials and the solvent, effectively improving the dissolution efficiency, and the second stirring blade can accelerate the molecular collision and mixing between the solvent and the drug raw materials, effectively increasing the dissolution speed, and effectively generating multiple different stirring areas, so that the concentration gradient in the solution is more uniform, effectively reducing the phenomenon of local over-concentration or over-diluted, and effectively making the drug raw materials fully mixed and reacted during the dissolution process, thereby effectively improving the quality and stability of the product.

[0007] Preferably, a water pump is fixedly connected to the middle of the first dissolution barrel; the water pump is fixedly connected to the outside of the first dissolution barrel; a water inlet pipe is fixedly connected to the middle of the water pump; a first telescopic hose is fixedly connected to the middle of the water pump; the middle of the first telescopic hose passes through the side wall of the first dissolution barrel; the end of the first telescopic hose is fixedly connected to a drain pipe; the drain pipe is fixedly connected to the middle of the second dissolution barrel; the end of the drain pipe is fixedly connected to a second telescopic hose; the middle of the second telescopic hose passes through the side wall of the first dissolution barrel; by discharging hot water or cold water into the drain pipe and controlling the temperature during the dissolution of the drug raw materials, the dissolution efficiency of some drugs can be accelerated at a specific temperature, and the rate of drug dissolution can be increased. Appropriate temperature control can keep the drug stable during the dissolution process, increase the effect of drug dissolution, and effectively reduce the problem of drug precipitation or crystallization, thereby improving the quality and stability of drug dissolution.

[0008] Preferably, the side wall of the second dissolution barrel is provided with two sliding grooves; a slider is slidably connected to the middle of the sliding groove; the ends of the two sliders are fixedly connected to a connecting rod; a scraper is fixedly connected to the middle of the connecting rod; the end of the scraper is in contact with the side wall of the second dissolution barrel; a third magnet is fixedly connected to the middle of the connecting rod; the third magnet is fixedly connected to the side away from the connecting rod; the third magnet and the first magnet are attracted when they are close to each other; the scraper can effectively reduce the drug raw materials adsorbed on the inner wall of the second dissolution barrel, effectively reduce the agglomeration and sedimentation of the drug raw materials on the inner wall of the second dissolution barrel, effectively reduce the sedimentation that hinders the contact between the solvent and the undissolved drug raw materials, effectively make the solvent and the drug raw materials fully contact, thereby improving the efficiency of the dissolution of the drug raw materials, effectively reducing the sediment on the inner wall of the second dissolution barrel that is not cleaned in time and gradually falls off and mixes into the drug solvent, resulting in uneven concentration of the solution, so that the drug concentration in the solution remains consistent, and can effectively reduce cross-contamination between different drugs.

[0009] Preferably, a quantitative plate is fixedly connected to the middle of the first rotating rod; the quantitative plate is fixedly connected to the second dissolving barrel near the top; a through hole is opened in the middle of the quantitative plate; the through hole is consistent with the diameter of the feed tube; the top of the quantitative plate is in contact with the bottom of the feed tube; the drug raw materials are added in sections through the quantitative plate, which can better control the dissolution rate, so that the drug maintains a stable concentration during the dissolution process, can effectively carry out subsequent crystal formation and control, can effectively reduce the uneven dissolution caused by adding a large amount of drug raw materials at one time, reduce the problem of some raw materials failing to dissolve in time to form lumps or deposits, effectively dissolve the drug raw materials gradually, and effectively improve the uniformity of drug dissolution.

[0010] Preferably, a mesh plate is fixed to the bottom of the quantitative plate; the mesh plate is fixed at the corresponding through-hole position; a second fixed rod is fixed to the side wall of the second dissolving barrel; a plurality of groups of bristles are fixed to the middle of the second fixed rod; the mesh plate can effectively reduce the mixing of various dust and impurities inside the drug raw materials, effectively reduce the presence of impurities inside the drug raw materials to reduce the solubility and purity of the drugs, increase the purity of the drug raw materials, and effectively reduce the large solid particles or impurities in the drug raw materials that directly enter the second dissolving barrel, reduce the problem of wear on the second dissolving barrel, increase the purity of the drug raw materials, enable a larger contact area with the solvent, and effectively increase the rapid dissolution of the drug.

[0011] Preferably, a second support rod is fixedly connected to the middle of the first rotating rod; a roller is rotatably connected to the middle of the second support rod; multiple groups of blades are fixedly connected to the middle of the roller; the multiple groups of blades are equidistantly distributed in the middle of the second support rod; the blades can effectively break the agglomeration state of the drug raw materials, effectively increase the contact area between the drug raw materials and the solvent, and can continuously redisperse the precipitate into the solution during the dissolution process of the drug raw materials, effectively reducing the deposition of the drug raw materials at the bottom of the second dissolution barrel or the formation of lumps.

[0012] The beneficial effects of the utility model are as follows:

[0013] 1. The crystalline drug production and preparation device described in the present invention can distribute the drug raw materials more evenly in the solvent by shaking the second dissolving barrel through the electric push rod, effectively reduce the aggregation and precipitation of the drug raw materials when dissolving inside the second dissolving barrel, effectively increase the contact area between the drug raw materials and the solvent, effectively improve the dissolution efficiency, and accelerate the molecular collision and mixing between the solvent and the drug raw materials through the second stirring blade, effectively increase the dissolution speed, effectively reduce the phenomenon of local over-concentration or over-diluted, and effectively make the drug raw materials fully mixed and react during the dissolution process.

[0014] 2. The crystalline drug production and preparation device described in the present invention controls the temperature during the dissolution of drug raw materials by discharging hot water or cold water into the drain pipe, thereby accelerating the dissolution efficiency of some drugs at a specific temperature and increasing the rate of drug dissolution. Appropriate temperature control can maintain the stability of the drug during the dissolution process and increase the effect of drug dissolution. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The present invention will be further described below with reference to the accompanying drawings.

[0016] Figure 1 This is a three-dimensional diagram of a crystal drug production and preparation device in the present utility model;

[0017] Figure 2 It is a structural schematic diagram of the second dissolving barrel in the utility model;

[0018] Figure 3 This is a schematic structural diagram of the blade in the utility model;

[0019] Figure 4 This is a schematic structural diagram of the second stirring blade in the present invention;

[0020] Figure 5 It is a structural diagram of the scraper in the utility model;

[0021] In the figure: 1. second dissolving barrel; 10. spring; 11. electric push rod; 12. first fixed rod; 13. first magnet; 14. first support rod; 15. rotating shaft; 16. second rotating rod; 17. second stirring blade; 18. second magnet; 2. water pump; 21. water inlet pipe; 22. first telescopic hose; 23. drain pipe; 24. second telescopic hose; 3. chute; 31. slider; 32. connecting rod; 33. scraper; 34. third magnet; 4. quantitative plate; 41. through hole; 5. mesh plate; 51. second fixed rod; 52. bristles; 6. second support rod; 61. roller; 62. blade; 8. first dissolving barrel; 81. feed pipe; 82. fixed frame; 83. motor; 84. first rotating rod; 85. first stirring blade. DETAILED DESCRIPTION

[0022] In order to make the technical means, creative features, objectives and effects achieved by the present invention easier to understand, the present invention is further described below in conjunction with specific implementation methods.

[0023] like Figures 1 to 5As shown, a crystalline drug production and preparation device according to an embodiment of the present invention comprises a first dissolving barrel 8; a feeding pipe 81 is fixedly connected to the top of the first dissolving barrel 8; two fixing frames 82 are fixedly connected to the top of the first dissolving barrel 8; the two fixing frames 82 are arranged opposite to each other; the ends of the two fixing frames 82 are fixedly connected to a motor 83; the output end of the motor 83 is fixedly connected to a first rotating rod 84; the middle of the first rotating rod 84 passes through the top of the first dissolving barrel 8; the middle of the first rotating rod 84 is fixedly connected to multiple groups of first stirring blades 85; the bottom of the first dissolving barrel 8 is fixedly connected to multiple groups of springs 10; multiple groups of springs 10 are fixedly connected to the inside of the first dissolving barrel 8; the ends of multiple groups of springs 10 are fixedly connected to the second dissolving barrel 1; the side wall of the first dissolving barrel 8 is fixedly connected to Two electric push rods 11; the two electric push rods 11 are arranged opposite to each other; the ends of the electric push rods 11 are fixedly connected to the side wall of the second dissolving barrel 1; the ends of the two first stirring blades 85 are fixedly connected to the first fixing rod 12; the end of the first fixing rod 12 is fixedly connected to the first magnet 13; the middle part of the first stirring blade 85 is fixedly connected to the first support rod 14; the end of the first support rod 14 is fixedly connected to the rotating shaft 15; the second rotating rod 16 is fixedly connected to the two opposite ends of the rotating shaft 15; the middle part of the second rotating rod 16 is fixedly connected to multiple groups of second stirring blades 17; multiple groups of second stirring blades 17 are equidistantly distributed in the middle part of the second rotating rod 16; the side wall of the second stirring blade 17 is fixedly connected to the second magnet 18; the first magnet 13 and the second magnet 18 repel each other when they are close to each other; working When the raw material is put into the second dissolving barrel 1 from the end of the feeding pipe 81, the raw material is allowed to enter the second dissolving barrel 1, the motor 83 is turned on to rotate the output end, the first rotating rod 84 is rotated by the motor 83, the raw material is stirred by the first stirring blade 85, and the dissolved drug raw materials are mixed by the first stirring blade 85, and then the electric push rod 11 is controlled to stretch to make the second dissolving barrel 1 shake, and the spring 10 is used to support it as the second dissolving barrel 1 shakes. In the process of stirring the drug raw materials, the first magnet 13 and the second magnet 18 are repelled when they are close to each other, so that the second stirring blade 17 moves away from the first magnet 13 and the second magnet 18 on the next second stirring blade 17 is close to the first magnet 13, and the above operation is repeated to make the second stirring blade 17 pass The rotating shaft 15 rotates to fully stir and mix the dissolved drug raw materials. The electric push rod 11 is used to shake the second dissolving barrel 1, so that the drug raw materials can be distributed more evenly in the solvent, effectively reducing the aggregation and precipitation of the drug raw materials when dissolving inside the second dissolving barrel 1, and can effectively increase the contact area between the drug raw materials and the solvent, and can effectively improve the dissolution efficiency. The second stirring blade 17 can accelerate the molecular collision and mixing between the solvent and the drug raw materials, effectively increase the dissolution speed, and can effectively generate multiple different stirring areas, so that the concentration gradient in the solution is more uniform, effectively reducing the phenomenon of local over-concentration or over-diluted, and can effectively make the drug raw materials fully mixed and react during the dissolution process, thereby effectively improving the quality and stability of the product.

[0024] like Figure 2 As shown, a water pump 2 is fixedly connected to the middle of the first dissolving barrel 8; the water pump 2 is fixedly connected to the outside of the first dissolving barrel 8; a water inlet pipe 21 is fixedly connected to the middle of the water pump 2; a first telescopic hose 22 is fixedly connected to the middle of the water pump 2; the middle of the first telescopic hose 22 passes through the side wall of the first dissolving barrel 8; the end of the first telescopic hose 22 is fixedly connected to a drain pipe 23; the drain pipe 23 is fixedly connected to the middle of the second dissolving barrel 1; the end of the drain pipe 23 is fixedly connected to a second telescopic hose 24; the middle of the second telescopic hose 24 passes through the side wall of the first dissolving barrel 8; during operation, when the drug raw materials are dissolved in the second dissolving barrel 1, hot water or cooling water is added from the end of the water inlet pipe 21 to pump the water pump 2. After opening, water flows through the first telescopic hose 22 into the drain pipe 23. When the second dissolving barrel 1 shakes, the first telescopic hose 22 and the second telescopic hose 24 extend and bend along with the second dissolving barrel 1, and water flows through the drain pipe 23 and is discharged from the end of the second telescopic hose 24. By discharging hot water or cold water into the drain pipe 23, the temperature is controlled during the dissolution of the drug raw materials, so that the dissolution efficiency of some drugs can be accelerated at a specific temperature, thereby increasing the rate of drug dissolution. Appropriate temperature control can keep the drug stable during the dissolution process, thereby increasing the effect of drug dissolution and effectively reducing the problem of drug precipitation or crystallization, thereby improving the quality and stability of drug dissolution.

[0025] like Figure 2 、 Figure 3 、 Figure 5As shown, the side wall of the second dissolving barrel 1 is provided with two chutes 3; a slider 31 is slidably connected to the middle of the chutes 3; the ends of the two sliders 31 are fixedly connected to a connecting rod 32; a scraper 33 is fixedly connected to the middle of the connecting rod 32; the end of the scraper 33 is in contact with the side wall of the second dissolving barrel 1; a third magnet 34 is fixedly connected to the middle of the connecting rod 32; the third magnet 34 is fixedly connected to the side away from the connecting rod 32; the third magnet 34 is attracted to the first magnet 13 when they are close to each other; during operation, when the first magnet 13 rotates through the first fixed rod 12, one of the first magnets 13 and the third magnet 34 is close to generate suction, so that the third magnet 34 is connected to the first magnet 13, and when the first magnet 13 rotates, it drives the connecting magnet 34 to rotate. The rod 32 rotates at the same time, causing the slider 31 to slide inside the chute 3, and the side wall is cleaned by the end of the scraper 33 fitting against the surface of the second dissolving barrel 1. The scraper 33 can effectively reduce the drug raw materials adsorbed on the inner wall of the second dissolving barrel 1, and can effectively reduce the agglomeration and sedimentation of the drug raw materials on the inner wall of the second dissolving barrel 1, effectively reduce the sediment hindering the contact between the solvent and the undissolved drug raw materials, effectively make the solvent and the drug raw materials fully contact, thereby improving the efficiency of the dissolution of the drug raw materials, and effectively reduce the sediment on the inner wall of the second dissolving barrel 1 that is not cleaned in time and gradually falls off and mixes into the drug solvent, resulting in uneven concentration of the solution, so that the drug concentration in the solution is consistent, and can effectively reduce cross contamination between different drugs.

[0026] like Figures 2 to 5 As shown, a quantitative plate 4 is fixedly connected to the middle of the first rotating rod 84; the quantitative plate 4 is fixedly connected to the second dissolving barrel 1 near the top; a through hole 41 is opened in the middle of the quantitative plate 4; the through hole 41 is consistent with the diameter of the feed pipe 81; the top of the quantitative plate 4 is in contact with the bottom of the feed pipe 81; during operation, when the first rotating rod 84 rotates, it drives the quantitative plate 4 to rotate. When the through hole 41 coincides with the bottom of the feed pipe 81, the drug raw material enters the second dissolving barrel 1 through the middle of the through hole 41, so that the drug raw material is added in sections. The segmented addition of the drug raw material through the quantitative plate 4 can better control the dissolution rate, maintain a stable concentration of the drug during the dissolution process, effectively carry out subsequent crystal formation and control, effectively reduce the uneven dissolution caused by adding a large amount of drug raw materials at one time, reduce the problem of some raw materials failing to dissolve in time to form lumps or deposits, effectively dissolve the drug raw materials gradually, and effectively improve the uniformity of drug dissolution.

[0027] like Figures 2 to 5As shown, a mesh plate 5 is fixed to the bottom of the quantitative plate 4; the mesh plate 5 is fixed to the position corresponding to the through hole 41; a second fixing rod 51 is fixed to the side wall of the second dissolving barrel 1; a plurality of groups of bristles 52 are fixed to the middle of the second fixing rod 51; during operation, when the drug raw material passes through the through hole 41 and enters the second dissolving barrel 1, it is first filtered through the mesh plate 5. When the quantitative plate 4 rotates, when the bottom of the mesh plate 5 passes through the bristles 52, the bottom of the mesh plate 5 is cleaned by the contact between the end of the bristles 52 and the bottom of the mesh plate 5. The mesh plate 5 can effectively reduce the mixing of various dust and impurities into the drug raw materials, effectively reduce the presence of impurities in the drug raw materials to reduce the solubility and purity of the drugs, increase the purity of the drug raw materials, and effectively reduce the large solid particles or impurities in the drug raw materials directly entering the second dissolving barrel 1, reduce the problem of wear on the second dissolving barrel 1, increase the purity of the drug raw materials, and increase the contact area with the solvent, effectively increase the rapid dissolution of the drug.

[0028] like Figure 2 and Figure 3 As shown, a second support rod 6 is fixedly connected to the middle of the first rotating rod 84; a roller 61 is rotatably connected to the middle of the second support rod 6; a plurality of groups of blades 62 are fixedly connected to the middle of the roller 61; the plurality of groups of blades 62 are equidistantly distributed in the middle of the second support rod 6; during operation, when the first rotating rod 84 rotates, the second support rod 6 rotates simultaneously with the first rotating rod 84. During the rotation of the second support rod 6, the blade 62 contacts the bottom of the second dissolving barrel 1 and rotates in the middle of the second support rod 6 through the roller 61. The blade 62 can effectively break the agglomeration state of the drug raw materials, effectively increase the contact area between the drug raw materials and the solvent, and can continuously redisperse the precipitate into the solution during the dissolution of the drug raw materials, effectively reducing the deposition of the drug raw materials at the bottom of the second dissolving barrel 1 or the formation of lumps.

[0029] During operation, the raw materials are put into the second dissolving barrel 1 from the end of the feeding tube 81, and the raw materials are allowed to enter the second dissolving barrel 1. The motor 83 is turned on to rotate the output end, and the first rotating rod 84 is rotated by the motor 83, and the raw materials are stirred by the first stirring blade 85. The dissolved drug raw materials are mixed by the first stirring blade 85, and then the electric push rod 11 is controlled to stretch to make the second dissolving barrel 1 shake, and the spring 10 is used to support it as the second dissolving barrel 1 shakes. In the process of stirring the drug raw materials, the first magnet 13 and the second magnet 18 are close to each other and repel each other, so that the second stirring blade 17 is away from the first magnet 13. The second magnet 18 on the next second stirring blade 17 is moved and brought close to the first magnet 13. The above operation is repeated to rotate the second stirring blade 17 through the rotating shaft 15 to fully stir and mix the dissolved medicinal raw materials. In the process of dissolving the medicinal raw materials in the second dissolving barrel 1, hot water or cooling water is added from the end of the water inlet pipe 21. After the water pump 2 is turned on, the water flows through the first telescopic hose 22 into the drain pipe 23. When the second dissolving barrel 1 shakes, the first telescopic hose 22 and the second telescopic hose 24 are telescopically bent along with the second dissolving barrel 1, and the water flows through the drain pipe 2 3 is discharged from the end of the second telescopic hose 24. When the first magnet 13 rotates through the first fixed rod 12, one of the first magnets 13 and the third magnet 34 approaches to generate suction, so that the third magnet 34 is connected to the first magnet 13. When the first magnet 13 rotates, the connecting rod 32 is driven to rotate at the same time, so that the slider 31 slides inside the chute 3. The end of the scraper 33 is in contact with the surface of the second dissolving barrel 1 to clean the side wall. When the first rotating rod 84 rotates, it drives the quantitative plate 4 to rotate. When the through hole 41 coincides with the bottom of the feeding pipe 81, the drug raw material passes through the through hole 41. The middle part enters the second dissolving barrel 1, so that the drug raw materials are added in sections. When the drug raw materials enter the second dissolving barrel 1 through the through hole 41, they are first filtered through the mesh plate 5. When the quantitative plate 4 rotates, the bottom of the mesh plate 5 passes through the brush 52, and the bottom of the mesh plate 5 is cleaned by the contact between the end of the brush 52 and the bottom of the mesh plate 5. When the first rotating rod 84 rotates, the second support rod 6 rotates simultaneously with the first rotating rod 84. During the rotation of the second support rod 6, the blade 62 contacts the bottom of the second dissolving barrel 1 and rotates in the middle of the second support rod 6 through the roller 61.

[0030] The above shows and describes the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are merely illustrative of the principles of the present invention. Various changes and improvements may be made to the present invention without departing from the spirit and scope of the present invention. Such changes and improvements are intended to fall within the scope of the present invention. The scope of protection claimed in this invention is defined by the appended claims and their equivalents.

Claims

1. A crystalline drug production and preparation device, comprising a first dissolution tank (8); characterized in that: A feed pipe (81) is fixedly connected to the top of the first dissolving barrel (8); two fixing frames (82) are fixedly connected to the top of the first dissolving barrel (8); the two fixing frames (82) are arranged opposite to each other; motors (83) are fixedly connected to the ends of the two fixing frames (82); a first rotating rod (84) is fixedly connected to the output end of the motor (83); the middle part of the first rotating rod (84) passes through the top of the first dissolving barrel (8); a plurality of first stirring blades (85) are fixedly connected to the middle part of the first rotating rod (84); a plurality of springs (10) are fixedly connected to the bottom of the first dissolving barrel (8); the plurality of springs (10) are fixedly connected to the inside of the first dissolving barrel (8); the ends of the plurality of springs (10) are fixedly connected to the second dissolving barrel (1); two electric push rods (11) are fixedly connected to the side wall of the first dissolving barrel (8); the two electric push rods (1 1) are arranged oppositely; the end of the electric push rod (11) is fixedly connected to the side wall of the second dissolving barrel (1); the ends of the two first stirring blades (85) are fixedly connected to the first fixing rod (12); the end of the first fixing rod (12) is fixedly connected to the first magnet (13); the middle of the first stirring blade (85) is fixedly connected to the first support rod (14); the end of the first support rod (14) is fixedly connected to the rotating shaft (15); the second rotating rod (16) is fixedly connected to the two opposite ends of the rotating shaft (15); the middle of the second rotating rod (16) is fixedly connected to multiple groups of second stirring blades (17); the multiple groups of second stirring blades (17) are equidistantly distributed in the middle of the second rotating rod (16); the side wall of the second stirring blade (17) is fixedly connected to the second magnet (18); the first magnet (13) and the second magnet (18) repel each other when they are close to each other.

2. A crystalline drug production and preparation device according to claim 1, characterized in that: A water pump (2) is fixedly connected to the middle of the first dissolving barrel (8); the water pump (2) is fixedly connected to the outside of the first dissolving barrel (8); a water inlet pipe (21) is fixedly connected to the middle of the water pump (2); a first telescopic hose (22) is fixedly connected to the middle of the water pump (2); the middle of the first telescopic hose (22) passes through the side wall of the first dissolving barrel (8); a drain pipe (23) is fixedly connected to the end of the first telescopic hose (22); the drain pipe (23) is fixedly connected to the middle of the second dissolving barrel (1); a second telescopic hose (24) is fixedly connected to the end of the drain pipe (23); the middle of the second telescopic hose (24) passes through the side wall of the first dissolving barrel (8).

3. A crystalline drug production and preparation device according to claim 2, characterized in that: The side wall of the second dissolving barrel (1) is provided with two sliding grooves (3); a slider (31) is slidably connected to the middle of the sliding groove (3); the ends of the two sliders (31) are fixedly connected to a connecting rod (32); a scraper (33) is fixedly connected to the middle of the connecting rod (32); the end of the scraper (33) is in contact with the side wall of the second dissolving barrel (1); a third magnet (34) is fixedly connected to the middle of the connecting rod (32); the third magnet (34) is fixedly connected to the side away from the connecting rod (32); the third magnet (34) and the first magnet (13) attract each other when they are close to each other.

4. A crystalline drug production and preparation device according to claim 3, characterized in that: A quantitative plate (4) is fixedly connected to the middle of the first rotating rod (84); the quantitative plate (4) is fixedly connected to a position near the top of the second dissolving barrel (1); a through hole (41) is opened in the middle of the quantitative plate (4); the diameter of the through hole (41) is consistent with that of the feed pipe (81); the top of the quantitative plate (4) is in contact with the bottom of the feed pipe (81).

5. A crystalline drug production and preparation device according to claim 4, characterized in that: A mesh plate (5) is fixedly connected to the bottom of the quantitative plate (4); the mesh plate (5) is fixedly connected to the position corresponding to the through hole (41); a second fixing rod (51) is fixedly connected to the side wall of the second dissolving barrel (1); and a plurality of groups of brush bristles (52) are fixedly connected to the middle of the second fixing rod (51).

6. A crystalline drug production and preparation device according to claim 5, characterized in that: A second support rod (6) is fixedly connected to the middle of the first rotating rod (84); a roller (61) is rotatably connected to the middle of the second support rod (6); a plurality of groups of blades (62) are fixedly connected to the middle of the roller (61); and the plurality of groups of blades (62) are equidistantly distributed in the middle of the second support rod (6).