Ultrafiltration concentration device for animal serum protein

Abstract

The utility model discloses an ultrafiltration concentration device for animal serum protein, which relates to the technical field of serum protein concentration and comprises a base, a frame and a plurality of filter cartridges. The plurality of filter cartridges are mounted on the rack and are used for concentrating serum protein; the rack comprises a front-end support and a rear-end support, a lower mounting frame is hinged to the front-end support and connected with the bottom of the filter cartridge, an upper mounting frame is connected to the upper end of the filter cartridge, a telescopic mechanism is hinged to the upper mounting frame, and the other end of the telescopic mechanism is hinged to the rear-end support; the utility model has the beneficial effects that the filter cartridges are connected into a whole and hinged on the front-end bracket through the upper mounting frame and the lower mounting frame, the filter cartridges are inclined or laid flat through the telescopic mechanism during maintenance, a worker does not need to use a ladder stand or a lifting platform during operation, the filter elements are convenient to take out, and the operation difficulty is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of serum protein concentration, in particular to an ultrafiltration concentration device for animal serum protein. Background Art

[0002] Concentrated animal serum protein refers to serum extracted from animal blood. Concentrated animal serum protein can be used in cell culture, biological product production, scientific research and diagnostic reagents, etc.

[0003] Ultrafiltration concentration technology is commonly used for animal serum protein concentration. Ultrafiltration concentration is a liquid treatment process based on membrane separation technology, which is mainly used to separate, purify and concentrate macromolecules or fine particles from solutions. This process uses a semipermeable membrane with a specific pore size (generally between 1.0 and 20.0 nanometers, sometimes larger) as a filter medium. Under a certain pressure difference, water molecules and small molecules can pass through the membrane pores, while relatively large solute molecules such as proteins, polysaccharides, nucleic acids, etc. are retained on one side of the membrane, thereby achieving solution concentration.

[0004] The ultrafiltration concentration device includes a frame, several filter cartridges, etc. A filter element is arranged in the filter cartridge. After the concentrated serum protein enters the filter element, the filter element is pressurized to accelerate the concentration and separation of the animal serum protein.

[0005] During the use of the existing ultrafiltration concentration device, some problems were found: the ultrafiltration concentration device generally includes multiple filter cartridges, which are difficult to disassemble, and the filter element in the filter cartridge needs to be replaced and cleaned regularly. When replacing the filter element, it is necessary to first remove the top cartridge cover and then take out the internal filter element. Since the filter cartridge is a slender cylindrical structure, it is necessary to use equipment such as ladders or lifting platforms when operating. In addition, there are many filter cartridges, which results in a large workload and cumbersome operation.

[0006] The utility model patent with publication number CN215654720U discloses an enzyme preparation ultrafiltration membrane concentration and separation system, which includes a plurality of filter tanks and a mounting frame. The bottom of the filter tank is supported by a bottom bracket, and a top cover is provided on the top. The height of the top cover can be adjusted by an adjusting rod, and the top cover is pressed on the top of the filter tank to fix the filter tank. When installing the filter tank, the filter tanks are placed on the bottom bracket in sequence. After all the filter tanks in the same row are placed, the height of the adjusting rod is adjusted by adjusting the assembly so that the top cover is pressed on the top of the filter tank to fix the filter tank. The operation is simple. If the filter tank needs to be removed, just lift the top cover by adjusting the assembly. The above structure makes the filter tank of the enzyme preparation ultrafiltration membrane concentration and separation system easy and stable to fix.

[0007] The filter tank of the disclosed solution is easy to disassemble, but when replacing the filter element, it is necessary to first remove the entire filter tank and then take out the filter element. The filter tank needs to be installed again later, which increases the operation steps. Utility Model Content

[0008] The purpose of the utility model is to provide an ultrafiltration and concentration device for animal serum protein in order to solve the above problems.

[0009] The utility model achieves the above-mentioned purpose through the following technical solutions:

[0010] An ultrafiltration and concentration device for animal serum protein, comprising:

[0011] Base;

[0012] A frame, which is fixedly mounted on the base;

[0013] A plurality of filter cartridges are mounted on the frame, and the filter cartridges are used for concentrating serum proteins;

[0014] The frame includes a front end bracket and a rear end bracket, the front end bracket is hinged with a lower mounting frame, the lower mounting frame is connected to the bottom of the filter cartridge, the upper end of the filter cartridge is connected to an upper mounting frame, the upper mounting frame is hinged with a telescopic mechanism, and the other end of the telescopic mechanism is hinged with the rear end bracket.

[0015] As a further improvement, the telescopic mechanism is a telescopic cylinder.

[0016] As a further improvement, the filter cartridge includes a cartridge body and a cartridge cover installed on the top of the cartridge body, a filter element is installed inside the cartridge body, a feed connector is connected to the cartridge cover, the top of the feed connector is sealed to the feed pipe, the bottom of the feed connector is sealed to the filter element, a discharge connector is fixedly connected to the bottom of the cartridge body, the top of the discharge connector is sealed to the filter element, the bottom of the discharge connector extends to the outside of the cartridge body and is sealed to the discharge pipe, a drainage hole is also provided at the bottom of the cartridge body, and the drainage hole is connected to the drainage pipe.

[0017] As a further improvement, a negative pressure pump is fixedly installed on the base, an exhaust hole is opened on the side of the cylinder, and the negative pressure pump is connected to the exhaust hole through a pipeline.

[0018] As a further improvement, bolts for connecting to the ground are provided at the four corners of the base.

[0019] Compared with the prior art, the beneficial effects of the utility model are:

[0020] The utility model connects the filter cartridges into one body and hinges them on the front bracket through the upper mounting frame and the lower mounting frame. During maintenance, the filter cartridges can be tilted or laid flat through the telescopic mechanism. Workers do not need to rely on ladders or lifting platforms during operation, which makes it convenient to take out the filter element and reduces the difficulty of operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0022] Figure 1 The utility model is a schematic diagram of the structure of an ultrafiltration and concentration device for animal serum protein.

[0023] Figure 2 It is a left view of an ultrafiltration concentration device for animal serum protein described in the utility model.

[0024] Figure 3 The utility model is a schematic diagram of the structure of a filter cartridge of an ultrafiltration concentration device for animal serum protein.

[0025] Figure 4 This is a reference diagram of the use status of an ultrafiltration concentration device for animal serum protein described in the utility model.

[0026] The following are the descriptions of the reference numerals:

[0027] 1. Base; 2. Negative pressure pump; 3. Frame; 31. Front bracket; 32. Rear bracket; 4. Lower mounting frame; 5. Filter cartridge; 51. Cylinder body; 52. Filter element; 53. Cylinder cover; 54. Feed connector; 55. Exhaust hole; 56. Drain hole; 57. Discharge connector; 6. Upper mounting frame; 7. Feed pipe; 8. Drain pipe; 9. Discharge pipe; 10. Telescopic mechanism. DETAILED DESCRIPTION

[0028] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", etc. are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0029] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0030] The utility model is further described below in conjunction with the accompanying drawings:

[0031] like Figure 1-Figure 4 As shown, the ultrafiltration concentration device for animal serum protein includes a base 1, a frame 3 and a plurality of filter cartridges 5.

[0032] The base 1 is fixed to the ground by bolts to prevent the device from tipping over due to the rotation of the filter cartridge 5. In other embodiments, a counterweight may be installed on the base 1 instead of fixing with bolts.

[0033] The frame 3 is fixedly mounted on the base 1, and includes a front end bracket 31 and a rear end bracket 32. The front end bracket 31 is hinged with a lower mounting frame 4, and the lower mounting frame 4 is connected to the bottom of the filter cartridge 5. The upper end of the filter cartridge 5 is connected to an upper mounting frame 6, and the upper mounting frame 6 is hinged with a telescopic mechanism 10, and the other end of the telescopic mechanism 10 is hinged to the rear end bracket 32. In this embodiment, the telescopic mechanism 10 is a telescopic cylinder. In other embodiments, the telescopic mechanism 10 can also adopt an electric telescopic mechanism 10 or a hydraulic telescopic mechanism 10.

[0034] A plurality of filter cartridges 5 are mounted on the frame 3, and the filter cartridges 5 are used to concentrate serum protein. The filter cartridge 5 comprises a barrel 51 and a barrel cover 53 mounted on the top of the barrel 51, the barrel cover 53 is connected to the barrel 51 through a flange, a filter element 52 is installed inside the barrel 51, the filter element 52 is used to filter animal serum protein, a feed connector 54 is connected to the barrel cover 53, the top of the feed connector 54 is sealedly connected to the feed pipe 7, the feed pipe 7 is used to transport the animal serum protein to be concentrated, the bottom of the feed connector 54 is sealedly connected to the filter element 52, a discharge connector 57 is fixedly connected to the bottom of the barrel 51, the top of the discharge connector 57 is sealedly connected to the filter element 52, the bottom of the discharge connector 57 extends to the outside of the barrel 51 and is sealedly connected to the discharge pipe 9, the discharge pipe 9 is used to transport the concentrated animal serum protein, and a drainage hole 56 is also opened at the bottom of the barrel 51, the drainage hole 56 is connected to the drainage pipe 8, and the drainage pipe 8 is used to discharge the filtered liquid. The feed connector 54 , the discharge connector 57 and the drain hole 56 are all equipped with solenoid valves for controlling on and off.

[0035] A negative pressure pump 2 is fixedly mounted on the base 1. The negative pressure pump 2 is used to draw a vacuum, so that negative pressure is formed inside the cylinder 51 to accelerate the filtration of serum proteins. An exhaust hole 55 is opened on the side of the cylinder 51. The negative pressure pump 2 is connected to the exhaust hole 55 through a pipeline. The pipeline in the utility model can be a flexible tube made of rubber material, which is convenient for the filter cylinder 5 to be tilted and flipped.

[0036] Working principle: During concentration, the animal serum protein to be concentrated is discharged into the filter element 52 of the filter cartridge 5 through the feed pipe 7, and then the solenoid valve of the feed connector 54 is closed, and the negative pressure pump 2 is started to form a negative pressure inside the filter cartridge 5 to accelerate the filtration of serum protein. After concentration, the serum protein is discharged through the discharge pipe 9, and the filtered liquid is discharged through the discharge pipe 8, completing the ultrafiltration concentration process.

[0037] When replacing the filter element 52 , the telescopic mechanism 10 is extended to tilt the filter cartridge 5 steadily until the filter cartridge 5 is substantially kept horizontal, so that the staff can open the cartridge cover 53 and take out the filter element 52 conveniently.

[0038] The basic principles, main features and advantages of the utility model are shown and described above. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, and these changes and improvements shall fall within the scope of the utility model to be protected.

Claims

1. An ultrafiltration concentration device for animal serum protein, comprising: Base (1); A frame (3) fixedly mounted on the base (1); A plurality of filter cartridges (5) are mounted on the frame (3), and the filter cartridges (5) are used for concentrating serum proteins; The invention is characterized in that: the frame (3) comprises a front end bracket (31) and a rear end bracket (32); a lower mounting frame (4) is hingedly connected to the front end bracket (31); the lower mounting frame (4) is connected to the bottom of the filter cartridge (5); the upper end of the filter cartridge (5) is connected to an upper mounting frame (6); the upper mounting frame (6) is hingedly connected to a telescopic mechanism (10); the other end of the telescopic mechanism (10) is hingedly connected to the rear end bracket (32).

2. The ultrafiltration concentration device for animal serum protein according to claim 1, characterized in that: The telescopic mechanism (10) is a telescopic cylinder.

3. The ultrafiltration concentration device for animal serum protein according to claim 1, characterized in that: The filter cartridge (5) comprises a cartridge body (51) and a cartridge cover (53) mounted on the top of the cartridge body (51); a filter element (52) is mounted inside the cartridge body (51); a feed connector (54) is connected to the cartridge cover (53); the top of the feed connector (54) is sealedly connected to a feed pipe (7); the bottom of the feed connector (54) is sealedly connected to the filter element (52); a discharge connector (57) is fixedly connected to the bottom of the cartridge body (51); the top of the discharge connector (57) is sealedly connected to the filter element (52); the bottom of the discharge connector (57) extends to the outside of the cartridge body (51) and is sealedly connected to a discharge pipe (9); a discharge hole (56) is also provided at the bottom of the cartridge body (51); the discharge hole (56) is connected to the discharge pipe (8).

4. The ultrafiltration concentration device for animal serum protein according to claim 3, characterized in that: A negative pressure pump (2) is fixedly mounted on the base (1), an exhaust hole (55) is provided on the side of the cylinder (51), and the negative pressure pump (2) is connected to the exhaust hole (55) via a pipeline.

5. The ultrafiltration concentration device for animal serum protein according to claim 1, characterized in that: The four corners of the base (1) are provided with bolts for connecting to the ground.

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