Blood sample analyzer

Abstract

The utility model discloses a blood sample analyzer. The blood sample analyzer comprises a first injector, a second injector, an erythrocyte sedimentation rate detection module and a sampling needle. Wherein the first injector and the second injector with different measuring ranges are arranged in series, and one end of the erythrocyte sedimentation rate detection module is connected with the second end of the second injector; the sampling needle is connected with the other end of the erythrocyte sedimentation rate detection module; wherein one of the first injector and the second injector with a smaller measuring range is configured to execute at least one of sample collection and distribution through the sampling needle, and one of the first injector and the second injector with a larger measuring range is configured to execute at least one of uniform mixing and depolymerization of the sample in the erythrocyte sedimentation rate detection module and sample collection through the sampling needle. According to the blood sample analyzer, joint detection of other detection modules and the erythrocyte sedimentation rate detection module can be achieved, the pipeline structure is simple, and the cost is low.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a blood sample analyzer. Background Art

[0002] The blood sample analyzer is a medical precision instrument that can be used to analyze and measure blood samples. In blood test analysis, the blood sample analyzer generally has an erythrocyte sedimentation rate detection module, which can generally be used to detect the sedimentation rate of red blood cells and assist in disease assessment based on the detection parameters.

[0003] When the blood sample analyzer performs erythrocyte sedimentation parameter testing, it first needs to deaggregate the red blood cells in the blood sample, that is, to make the red blood cells appear in a single dispersed state, and then measure the change in transmittance in the process of single dispersed red blood cells aggregating to an aggregated state, and then obtain the aggregation index or erythrocyte sedimentation rate.

[0004] In the existing sample analyzers, the erythrocyte sedimentation rate detection module usually uses a peristaltic pump or a separate driving component to perform depolymerization, which makes the pipeline structure of the blood sample analyzer complex and the cost high. Utility Model Content

[0005] The present application provides a blood sample analyzer to solve the technical problem in the prior art that the erythrocyte sedimentation rate detection module in the sample analyzer usually adopts a peristaltic pump or a separate driving component to perform depolymerization, resulting in a complex pipeline structure and high cost of the blood sample analyzer.

[0006] In order to solve the above technical problems, a technical solution adopted in the present application is: to provide a blood sample analyzer, which includes: a first syringe and a second syringe, the first syringe is connected to the first end of the second syringe, so that the first syringe and the second syringe are arranged in series, and the first syringe and the second syringe have different ranges; an erythrocyte sedimentation rate detection module, one end of the erythrocyte sedimentation rate detection module is connected to the second end of the second syringe; a sampling needle is connected to the other end of the erythrocyte sedimentation rate detection module; wherein, the one with a smaller range of the first syringe and the second syringe is configured to perform at least one of sample collection and distribution through the sampling needle, and the one with a larger range is configured to perform at least one of mixing, depolymerization, and sample collection through the sampling needle on the sample in the erythrocyte sedimentation rate detection module.

[0007] Furthermore, the measuring range of the first syringe is greater than the measuring range of the second syringe.

[0008] Furthermore, the blood sample analyzer also includes: a first cleaning module and a three-way valve, the first cleaning module is used to provide cleaning fluid, the first syringe is connected to the first end of the three-way valve, the second end of the three-way valve is connected to the first cleaning module, and the third end of the three-way valve is connected to the first end of the second syringe, the first syringe is used to absorb cleaning fluid from the first cleaning module, and use the cleaning fluid to clean the first syringe, the erythrocyte sedimentation rate detection module and the inner wall of the sampling needle.

[0009] Furthermore, the blood sample analyzer also includes a routine blood test module, which includes at least one reaction pool, and the sampling needle is configured to distribute samples to the reaction pool and / or the erythrocyte sedimentation rate detection module.

[0010] Further, the one with a smaller volume range among the first and second syringes is configured to draw samples through a sampling needle, and distribute the drawn samples to corresponding reaction pools and / or erythrocyte sedimentation rate detection modules in a set order; or, the one with a larger volume range among the first and second syringes is configured to draw samples through a sampling needle, and the one with a smaller volume range among the first and second syringes is configured to distribute the samples to corresponding reaction pools and / or erythrocyte sedimentation rate detection modules; the one with a larger volume range among the first and second syringes is configured to draw back and forth the samples distributed to the erythrocyte sedimentation rate detection module to mix or depolymerize the samples in the erythrocyte sedimentation rate module.

[0011] Furthermore, the one with a larger measuring range among the first and second syringes is configured to draw the cleaning fluid through the sampling needle, and the one with a smaller measuring range among the first and second syringes is configured to distribute the cleaning fluid to the corresponding reaction pool and / or erythrocyte sedimentation rate detection module.

[0012] Furthermore, the blood sample analyzer also includes a first pipeline and a second pipeline, the second end of the second syringe is connected to the sampling needle through the first pipeline, the erythrocyte sedimentation rate detection module includes a pipeline within a preset range of the first pipeline, and the first end of the second syringe is connected to the first syringe through the second pipeline.

[0013] Furthermore, the blood sample analyzer also includes a two-way valve, one end of the two-way valve is connected to the erythrocyte sedimentation rate detection module, and the other end of the two-way valve is connected to the second syringe.

[0014] Furthermore, the smaller one of the first syringe and the second syringe has a range of no more than 300ul, and the larger one of the first syringe and the second syringe has a range of no less than 2.5mL.

[0015] Furthermore, the blood sample analyzer also includes a cleaning swab and a second cleaning module. The cleaning swab is sleeved on the periphery of the sampling needle. The second cleaning module is connected to the cleaning swab. The second cleaning module is used to cooperate with the cleaning swab to clean the outer wall of the sampling needle.

[0016] Beneficial effects of the present application: Different from the prior art, the blood sample analyzer of the present application includes: a first syringe and a second syringe, an erythrocyte sedimentation rate detection module and a sampling needle. The first syringe and the second syringe with different measuring ranges are arranged in series, one end of the erythrocyte sedimentation rate detection module is connected to the second end of the second syringe; the sampling needle is connected to the other end of the erythrocyte sedimentation rate detection module; the one with a smaller measuring range of the first syringe and the second syringe is configured to collect and / or distribute samples through the sampling needle, and the one with a larger measuring range is configured to mix / disaggregate samples in the erythrocyte sedimentation rate detection module and / or collect samples through the sampling needle. The present application can achieve more accurate sampling and distribution of samples by connecting two syringes with different measuring ranges in series, and can also mix or disaggregate samples in the erythrocyte sedimentation rate detection module to achieve joint inspection of other detection modules and the erythrocyte sedimentation rate detection module, with a simple structure and low cost. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a structural schematic diagram of an embodiment of a blood sample analyzer provided by the present application. DETAILED DESCRIPTION

[0018] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. It is understandable that the specific embodiments described herein are only used to explain the present application, rather than to limit the present application. It should also be noted that, for ease of description, only some structures related to the present application are shown in the accompanying drawings, rather than all structures. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of this application.

[0019] The terms "first", "second", etc. in this application are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not limited to the listed steps or units, but optionally includes steps or units that are not listed, or optionally includes other steps or units inherent to these processes, methods, products or devices.

[0020] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0021] This application provides a blood sample analyzer, please refer to Figure 1 As shown, the blood sample analyzer 10 includes: a first syringe 11 and a second syringe 12 , an erythrocyte sedimentation rate detection module 13 and a sampling needle 14 .

[0022] The first syringe 11 is connected to the first end of the second syringe 12, so that the first syringe 11 and the second syringe 12 are arranged in series. The first syringe 11 and the second syringe 12 have different measuring ranges. The blood sample analyzer 10 also includes a second pipeline T2, and the first end of the second syringe 12 is connected to the first syringe 11 through the second pipeline T2.

[0023] The measuring range of the first syringe 11 may be greater than that of the second syringe 12. In this case, the first syringe 11 may be used to draw a large sample, and the volume of the large sample may usually exceed 130ul; the second syringe 12 may be used to draw a small sample, and the accuracy of the second syringe 12 is greater than that of the first syringe 11.

[0024] The measuring range of the first syringe 11 may also be smaller than that of the second syringe 12. In this case, the first syringe 11 can be used to draw a small sample, and the second syringe 12 can be used to draw a large sample. The accuracy of the first syringe 11 is greater than that of the second syringe 12.

[0025] The larger one of the first syringe 11 and the second syringe 12 has a range of not less than 2.5 ml. The smaller one of the first syringe 11 and the second syringe 12 has a range of not more than 300 ul, so that the small syringe has sufficient accuracy and the large syringe can absorb a sufficient amount of liquid.

[0026] One end of the erythrocyte sedimentation rate detection module 13 is connected to the second end of the second syringe 12, and the other end of the erythrocyte sedimentation rate detection module 13 is connected to the sampling needle 14. The erythrocyte sedimentation rate detection module 13 is used to detect the erythrocyte sedimentation rate.

[0027] The blood sample analyzer 10 further includes a first pipeline T1, the second end of the second syringe 12 is connected to the sampling needle 14 through the first pipeline T1, and the erythrocyte sedimentation rate detection module 13 includes a pipeline within a preset range of the first pipeline T1, that is, the erythrocyte sedimentation rate detection module 13 is arranged on the first pipeline T1, and a detection component is arranged in a partial section of the first pipeline T1 to form the erythrocyte sedimentation rate detection module 13. There is no need to separately arrange a pipeline for the erythrocyte sedimentation rate detection module 13, thus simplifying the structure of the blood sample analyzer 10 and saving costs.

[0028] The blood sample analyzer 10 further includes a two-way valve LV03, one end of which is connected to the ESR detection module 13, and the other end of which is connected to the second syringe 12. The two-way valve LV02 is used to control the connection and closing between the ESR detection module 13 and the second syringe 12.

[0029] When the two-way valve LV03 is connected, the first syringe 11 and the second syringe 12 are connected to the erythrocyte sedimentation rate detection module 13. When the two-way valve LV02 is closed, the first syringe 11 and the second syringe 12 are closed to the erythrocyte sedimentation rate detection module 13.

[0030] The one with a smaller range among the first syringe 11 and the second syringe 12 can be configured to perform at least one of collecting and distributing samples through the sampling needle 14. That is, the sample can be collected by the syringe with a small range, and the sample can also be distributed by the syringe with a small range. Since the accuracy of the syringe with a small range is higher, the accuracy of sampling and distribution can be improved by using the syringe with a small range for sample collection and / or distribution.

[0031] The one with a larger range among the first syringe 11 and the second syringe 12 is configured to perform at least one of mixing, disaggregation, and sample collection through a sampling needle on the sample in the erythrocyte sedimentation detection module 13. By collecting samples through a syringe with a larger range, a large sample can be collected at one time, and the large sample can be distributed to multiple detection modules, thereby improving the efficiency of sample detection. In addition, a large volume of cleaning liquid can be drawn through a syringe with a large range and a sampling needle, and the cleaning liquid can be distributed to multiple detection modules to clean multiple modules and improve the cleaning efficiency.

[0032] The blood sample analyzer 10 of the present application has a simple structure and low cost. By connecting two syringes with different measuring ranges in series, the erythrocyte sedimentation rate detection module can be jointly tested with other detection modules. Moreover, the efficiency and accuracy of sample distribution can be improved, and the reliability of sample detection can be improved.

[0033] Furthermore, the blood sample analyzer 10 may also include a blood routine module (not shown). The blood routine module includes a plurality of reaction pools. The sampling needle 14 is also configured to distribute samples to the reaction pools.

[0034] Optionally, the one with the smaller range of the first syringe 11 and the second syringe 12 is configured to draw a sample through the sampling needle 14, and distribute the drawn sample to the corresponding reaction pool and / or erythrocyte sedimentation detection module in a set order. Specifically, the small-range syringe can draw small samples respectively, and inject the small samples into the reaction pool or erythrocyte sedimentation detection module 13 in a set order. In this way, the collection and distribution of samples by a syringe with higher precision can improve the accuracy of sample collection and distribution, thereby improving the efficiency of sample detection. The large-range syringe can be drawn back and forth to mix or depolymerize the sample distributed in the erythrocyte sedimentation detection module 13. Among them, when the large-range syringe mixes or depolymerizes the sample in the erythrocyte sedimentation detection module 13, the number of back and forth pulls is not less than 2 times, and then the erythrocyte sedimentation parameters of the sample are measured by the detection component in the erythrocyte sedimentation detection module 13, thereby realizing the joint inspection of the blood routine module and the erythrocyte sedimentation detection module 13.

[0035] Optionally, the one with a larger range among the first syringe 11 and the second syringe 12 can be configured to draw the sample through the sampling needle 14, and the one with a smaller range among the first syringe 11 and the second syringe 12 can be configured to distribute the sample to the corresponding reaction pool and / or erythrocyte sedimentation detection module 13 in a set order. In this way, the number of sample sampling can be reduced, the efficiency of sample detection can be improved, and the accuracy of sample detection is also high. The one with a larger range among the first syringe 11 and the second syringe 12 can be configured to draw back and forth the sample distributed to the erythrocyte sedimentation detection module 13 to mix or depolymerize the sample in the erythrocyte sedimentation detection module 13.

[0036] Further, in Figure 1 In the illustrated embodiment, the measuring range of the first syringe 11 is greater than that of the second syringe 12, that is, a large number of syringes are connected in series to a syringe with a small measuring range, so that the syringe with a large measuring range can be used to clean the syringe with a small measuring range.

[0037] like Figure 1 As shown, the blood sample analyzer 10 further includes: a first cleaning module 15 and a three-way valve LV01, wherein the first cleaning module 15 is used to provide cleaning liquid. The first syringe 11 is connected to a first end of the three-way valve LV01, a second end of the three-way valve LV01 is connected to the first cleaning module 15, and a third end of the three-way valve LV01 is connected to a first end of the second syringe 12.

[0038] When the first end of the three-way valve LV01 is connected to the second end, the first syringe 11 can absorb the cleaning liquid from the first cleaning module. When the first end of the three-way valve LV01 is connected to the third end, the first syringe 11 injects the cleaning liquid into the second syringe 12, the erythrocyte sedimentation rate detection module 13, and the inner wall of the sampling needle 14 to clean the second syringe 12, the erythrocyte sedimentation rate detection module 13, the inner wall of the sampling needle 14 and the pipelines therebetween. In this way, the cleaning of the blood sample analyzer 10 can be completed in a shorter time by using a large syringe.

[0039] As mentioned above, the flow rate range for cleaning the inner wall of the sampling needle is within the range of 0.3-1.5 ml / s, which ensures that the sample on the inner wall of the sampling needle is cleaned and at the same time, the swab recovers the waste liquid without splashing or leaking.

[0040] Furthermore, when the blood sample analyzer 10 is maintained and cleaned, the one with a larger range of the first syringe 11 and the second syringe 12 can absorb the cleaning liquid in the test tube through the sampling needle 14, and the one with a smaller range of the first syringe 11 and the second syringe 12 is configured to inject the cleaning liquid into the corresponding reaction pool in sequence, thereby achieving one-time absorption of the cleaning liquid during the maintenance process of the entire machine, reducing the cleaning time of the blood sample analyzer 10 and reducing the manual waiting time.

[0041] Furthermore, the blood sample analyzer 10 can also include a cleaning swab 20 and a second cleaning module (not shown in the figure), the cleaning swab 20 is sleeved on the periphery of the sampling needle 14, the second cleaning module is connected to the cleaning swab 20, and the second cleaning module is used to cooperate with the cleaning swab 20 to clean the outer wall of the sampling needle 14.

[0042] Specifically, Figure 1 As shown, the second cleaning module includes a cleaning liquid supply module 21 and a power module 22. The cleaning liquid supply module 21 is connected to one end of the cleaning swab 20 through a two-way valve LV02, and the power module 22 is connected to the other end of the cleaning swab 20. The power module 22 draws cleaning liquid from the cleaning liquid supply module 21 so that the cleaning liquid of the power cleaning module 21 passes through the swab 20, thereby cleaning the outer wall of the sampling needle 14.

[0043] In summary, the blood sample analyzer 10 of the present application can achieve more accurate sampling and distribution of samples by connecting two syringes with different ranges in series, and can also mix or depolymerize the samples in the erythrocyte sedimentation rate detection module 13 to achieve joint detection of other detection modules and the erythrocyte sedimentation rate detection module 13, with a simple structure and low cost. In addition, the blood sample analyzer 10 of the present application can clean its own pipelines and reaction pools, and the cleaning efficiency is high.

[0044] The above description is only an implementation method of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A blood sample analyzer, characterized in that: The blood sample analyzer comprises: a first syringe and a second syringe, wherein the first syringe is connected to a first end of the second syringe so that the first syringe and the second syringe are arranged in series, and the first syringe and the second syringe have different measuring ranges; an erythrocyte sedimentation rate detection module, one end of which is connected to the second end of the second syringe; A sampling needle connected to the other end of the erythrocyte sedimentation rate detection module; Among them, the one with a smaller range among the first syringe and the second syringe is configured to perform at least one of collecting and distributing samples through the sampling needle, and the one with a larger range is configured to perform at least one of mixing, depolymerizing, and collecting samples through the sampling needle on the samples in the erythrocyte sedimentation detection module.

2. The blood sample analyzer according to claim 1, characterized in that: The measuring range of the first syringe is greater than the measuring range of the second syringe.

3. The blood sample analyzer according to claim 2, characterized in that: The blood sample analyzer further comprises: a first cleaning module and a three-way valve, wherein the first cleaning module is used to provide a cleaning solution, The first syringe is connected to the first end of the three-way valve, the second end of the three-way valve is connected to the first cleaning module, and the third end of the three-way valve is connected to the first end of the second syringe. The first syringe is used to absorb cleaning fluid from the first cleaning module, and use the cleaning fluid to clean the first syringe, the erythrocyte sedimentation rate detection module and the inner wall of the sampling needle.

4. The blood sample analyzer according to claim 1, characterized in that: The blood sample analyzer further comprises a routine blood test module, which comprises at least one reaction pool, and the sampling needle is configured to distribute samples to the reaction pool and / or the erythrocyte sedimentation rate detection module.

5. The blood sample analyzer according to claim 4, characterized in that: The one with a smaller measuring range among the first syringe and the second syringe is configured to draw a sample through the sampling needle and distribute the drawn sample to the corresponding reaction pool and / or erythrocyte sedimentation rate detection module according to a set order; or, The one with a larger volume range between the first syringe and the second syringe is configured to draw the sample through the sampling needle, and the one with a smaller volume range between the first syringe and the second syringe is configured to distribute the sample to the corresponding reaction pool and / or erythrocyte sedimentation rate detection module; the one with a larger volume range between the first syringe and the second syringe is configured to draw back and forth the sample distributed to the erythrocyte sedimentation rate detection module to mix or depolymerize the sample of the erythrocyte sedimentation rate detection module.

6. The blood sample analyzer according to claim 4, characterized in that: The one with a larger measuring range among the first and second syringes is configured to draw cleaning fluid through the sampling needle, and the one with a smaller measuring range among the first and second syringes is configured to distribute the cleaning fluid to the corresponding reaction pool and / or erythrocyte sedimentation rate detection module.

7. The blood sample analyzer according to claim 1, characterized in that: The blood sample analyzer also includes a first pipeline and a second pipeline, the second end of the second syringe is connected to the sampling needle through the first pipeline, the erythrocyte sedimentation rate detection module includes a pipeline within a preset range of the first pipeline, and the first end of the second syringe is connected to the first syringe through the second pipeline.

8. The blood sample analyzer according to claim 7, characterized in that: The blood sample analyzer further comprises a two-way valve, one end of which is connected to the erythrocyte sedimentation rate detection module, and the other end of which is connected to the second syringe.

9. The blood sample analyzer according to claim 1, characterized in that: The smaller one of the first syringe and the second syringe has a range of no more than 300ul, and the larger one of the first syringe and the second syringe has a range of no less than 2.5mL.

10. The blood sample analyzer according to claim 1, characterized in that: The blood sample analyzer also includes a cleaning swab and a second cleaning module. The cleaning swab is sleeved on the periphery of the sampling needle. The second cleaning module is connected to the cleaning swab. The second cleaning module is used to cooperate with the cleaning swab to clean the outer wall of the sampling needle.

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