Disposable drug delivery device for uterine cavity of rat

By designing a disposable uterine cavity doser in rats, using the combination of vaginal expansion components and hand pressing and plunger, uterine cavity dosing without dissection of rats is achieved, solving the problems of large workload and stress response in the prior art, and improving the convenience and reliability of the experiment.

CN222657257UActive Publication Date: 2025-03-25Zhongshan Boai Hospital (Zhongshan Maternal and Child Health Hospital, Zhongshan Maternal and Child Health and Family Planning Service Center, Zhongshan Women and Children's Hospital)
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Patent Information

Application Number
CN202420778368.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-15
Publication Date
2025-03-25
Estimated Expiration
2034-04-15

AI Technical Summary

Technical Problem

In the prior art, injecting drugs into the uterine cavity of rats requires dissection of the rats, which leads to a large workload and may cause stress responses or damage, affecting the experimental results.

Method used

A disposable rat uterine cavity dosage device is designed, including a needle tube, a needle holder, a perfusion needle, a plunger and a vaginal expansion assembly. The vagina of rats is expanded by the vaginal expansion component, combined with the combination of hand pressing and plunger, uterine administration can be completed without dissecting the rat.

Benefits of technology

It reduces the workload of staff, avoids stress response and damage in rats, and improves the reliability and convenience of the experiment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of auxiliary tools for laboratory rats, in particular to a disposable rat uterine cavity dosing device which comprises a needle tube, the top of the needle tube is fixedly connected with a needle seat, the top of the needle seat is fixedly connected with an infusion needle head, the bottom of the needle tube is movably connected with a plunger, one side of the plunger extends into the needle tube, and the other side of the plunger extends into the needle tube. An inner cavity of the needle tube is in sliding connection with the plunger, and a vaginal dilation assembly is arranged on the upper side of the needle tube and comprises a vaginal dilation shell. According to the disposable drug delivery device for the uterine cavity of the rat, when drug delivery needs to be conducted on the uterine cavity of the rat, the drug delivery work can be completed only by probing the perfusion probe into the vagina of the rat and probing the perfusion probe into the uterus from the cervix and then cooperating with a pressing hand, a plunger and other components, the rat does not need to be dissected, the workload of workers is reduced, and compared with an insulin needle in the prior art, the drug delivery device is convenient to use. The needle head is longer, the size of the vagina and the size of the cervix uteri of a rat can be better combined, the needle head can conveniently extend into the uterine cavity from the vagina for administration, and convenience is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of auxiliary tools for laboratory rats, in particular to a disposable uterine cavity drug delivery device for rats. Background Art

[0002] Rats are active at night and hide during the day. They like to live alone, are timid and easily startled. They have long incisors and like to chew. They are resistant to disease and are highly sensitive. They have relatively consistent genetics and are prone to bite when provoked, attacked or caught. Lactating female rats are especially dangerous and will often bite the hands of staff who put them into the cage when feeding them.

[0003] In the teaching and research of physiology, medicine, pharmacy and other disciplines, rats are needed as experimental animals. They are mainly used in experiments and inspections on the safety, toxicity and efficacy of food, cosmetics, drugs, biological products, industrial products, medicine and life sciences. Rats respond relatively similarly to experimental conditions and are known as precise biological research tools. They are widely used in research on endocrinology, drugs, behavior, geriatrics, tumors, infectious diseases, cardiovascular diseases and traditional Chinese medicine. There are multiple varieties and strains of rats for selection in different experiments. In some cases, staff will be required to inject drugs into the rat's uterine cavity.

[0004] In the current existing technology, most of the drugs are administered directly after dissecting rats and exposing the uterus. This method will greatly increase the workload of the experimenters, and the virus will cause stress or damage to the rats, which will affect the experimental results. Utility Model Content

[0005] The purpose of the utility model is to provide a disposable drug delivery device for rat uterine cavity to solve the problems raised in the above background technology. To achieve the above purpose, the utility model provides the following technical solution: a disposable drug delivery device for rat uterine cavity, comprising a needle tube, the top of the needle tube is fixedly connected to a needle seat, the top of the needle seat is fixedly connected to an infusion needle, the bottom of the needle tube is movably connected to a plunger, one side of the plunger extends to the inside of the needle tube, the inner cavity of the needle tube is slidably connected to the plunger, and a vaginal dilation component is arranged on the upper side of the needle tube.

[0006] Further preferably, the vaginal dilator assembly includes a vaginal dilator shell, which is sleeved on the outside of the perfusion needle. A through hole is opened on the top of the vaginal dilator shell. When it is necessary to administer drugs into the rat's uterine cavity, it is only necessary to insert the perfusion probe into the rat's vagina and into the uterus from the cervical opening. Subsequently, the drug administration can be completed with the cooperation of hand pressing, plunger and other components. There is no need to dissect the rat, which reduces the workload of the staff. Compared with the insulin needle in the prior art, the needle in the present application is longer and can better adapt to the size of the rat's vagina and cervix, which is convenient for inserting the drug into the uterine cavity from the vagina, thereby increasing convenience.

[0007] Further preferably, a support member is fixedly connected to the inner side of the vaginal dilator shell, a gas delivery cavity is provided at the inner end of the vaginal dilator shell, and a connecting tube is fixedly connected to the outer side of the vaginal dilator shell, which is used to connect the gas delivery cavity with the airbag to facilitate the gas to enter the interior of the airbag from the gas delivery cavity.

[0008] Further preferably, a fixed end is sleeved on one side of the outer side of the connecting tube, and an air bag is fixedly connected to the side of the fixed end away from the connecting tube. The vaginal dilator assembly is used to dilate the rat's vagina, which can easily expose the cervical opening and facilitate the staff to quickly complete the drug administration. The use of the air bag can support the rat's vagina, allowing the vaginal dilator shell to sit stably inside the rat's vagina, solving the problem of the vaginal dilator shell slipping out of the rat's vagina due to position movement.

[0009] Further preferably, the connecting tube and the airbag are fixedly connected, and a protective layer is fixedly connected to the outer surface of the airbag. The protective layer contacts the inner wall of the rat's vagina, thereby protecting the rat's vagina and preventing the rat from being injured.

[0010] Further preferably, a rubber tube is sleeved on the upper side of the outer side of the perfusion needle, a scale bar is provided on the front surface of the needle tube, and a button is fixedly connected to the bottom of the plunger. The experimenter can check the injection volume through the scale bar and thus control the injection volume.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] In the present invention, when it is necessary to administer drugs into the rat's uterine cavity, it is only necessary to insert the perfusion probe into the rat's vagina and into the uterus from the cervical opening, and then the drug administration can be completed by using components such as a hand press and a plunger. There is no need to dissect the rat, which reduces the workload of the staff. Compared with the insulin needle in the prior art, the needle in the present application is longer and can better meet the size of the rat's vagina and cervix, making it easier to insert the injection probe into the uterine cavity from the vagina, thereby increasing convenience.

[0013] In the utility model, the vaginal dilator component is used to dilate the rat's vagina, which can easily expose the cervical opening and facilitate the staff to quickly complete the medication work. The use of the air bag can support the rat's vagina, allowing the vaginal dilator shell to be stably located inside the rat's vagina, thus solving the problem of the vaginal dilator shell slipping out of the rat's vagina due to position movement. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0015] Figure 2 It is a schematic diagram of the three-dimensional structure of the utility model during use;

[0016] Figure 3 It is a schematic diagram of a partial three-dimensional structure of the utility model;

[0017] Figure 4 This is a schematic diagram of the cross-sectional structure of the vaginal expansion shell of the utility model;

[0018] Figure 5 This is an enlarged three-dimensional structural diagram of the local details of the vaginal expansion component of the utility model Figure 1 ;

[0019] Figure 6 This is an enlarged three-dimensional structural diagram of the local details of the vaginal expansion component of the utility model Figure 2 .

[0020] In the figure: 1, needle tube; 2, needle seat; 3, perfusion needle; 4, plunger; 5, vaginal dilation assembly; 501, vaginal dilation shell; 502, penetration port; 503, support member; 504, gas delivery cavity; 505, gas delivery end; 506, connecting tube; 507, fixed end; 508, air bag; 509, protective layer; 6, rubber tube; 7, scale bar; 8, hand press; DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technical personnel in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figure 1-Figure 6 The utility model provides a technical solution: a disposable rat intrauterine drug delivery device, comprising a needle tube 1, a needle seat 2 is fixedly connected to the top of the needle tube 1, an infusion needle 3 is fixedly connected to the top of the needle seat 2, a plunger 4 is movably connected to the bottom of the needle tube 1, one side of the plunger 4 extends to the inside of the needle tube 1, the inner cavity of the needle tube 1 is slidably connected to the plunger 4, and a vaginal dilation component 5 is arranged on the upper side of the needle tube 1.

[0023] In this embodiment, Figure 1 , Figure 2 , Figure 4 , Figure 5 and Figure 6As shown, the vaginal dilator assembly 5 includes a vaginal dilator shell 501, which is sleeved on the outside of the infusion needle 3. A through hole 502 is opened on the top of the vaginal dilator shell 501. A support member 503 is fixedly connected to the inner side of the vaginal dilator shell 501. A gas delivery cavity 504 is provided at the inner end of the vaginal dilator shell 501. A connecting tube 506 is fixedly connected to the outer side of the vaginal dilator shell 501. First, the vaginal dilator shell 501 can be placed into the rat's vagina to initially expand the rat's vagina. An external air pipe is connected to the gas delivery end 505 to deliver gas to the inside thereof, and then the gas can be delivered to the inside of the gas delivery cavity 504. The vaginal dilator shell 501 expands the rat's vagina, which can facilitate the subsequent work of the staff.

[0024] In this embodiment, Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6 As shown, a fixed end 507 is sleeved on one side of the outer side of the connecting tube 506, and a gas bag 508 is fixedly connected to the fixed end 507 away from the side of the connecting tube 506. The connecting tube 506 and the gas bag 508 are fixedly connected, and a protective layer 509 is fixedly connected to the outer surface of the gas bag 508. A rubber tube 6 is sleeved on the upper side of the outer side of the perfusion needle 3, and a scale bar 7 is provided on the front surface of the needle tube 1. A button 8 is fixedly connected to the bottom of the plunger 4. Since the gas delivery chamber 504 is connected to the gas bag 508 through the connecting tube 506, 8 are fixedly connected, so that gas can enter the interior of the airbag 508 through the connecting tube 506. The delivery of gas in the airbag 508 will cause it to expand, which can expand the rat's vagina. At this time, the protective layer 509 on the surface of the airbag 508 fits with the inner wall of the vagina. Then the staff inserts the infusion needle 3 into the rat's vagina through the through hole 502 on the vaginal dilator shell 501, and then inserts it into the uterus from the cervical opening. The hand button 8 is pressed to discharge the medicine in the needle tube 1 through the infusion needle 3, thereby completing the injection and drug administration.

[0025] The use method and advantages of the utility model: When the rat uterine cavity disposable drug delivery device is used, the working process is as follows:

[0026] like Figure 1 , Figure 2 , Figure 3 , Figure 4 , Figure 5 and Figure 6As shown, when in use, the vaginal dilator shell 501 can first be placed into the rat's vagina to initially dilate the rat's vagina, and an external air tube is connected to the gas delivery end 505 to deliver gas to the inside thereof, and then to the inside of the gas delivery chamber 504. Since the gas delivery chamber 504 is fixedly connected to the airbag 508 through the connecting tube 506, the gas can enter the inside of the airbag 508 through the connecting tube 506. The delivery of gas in the airbag 508 will cause it to expand, which can dilate the rat's vagina. At this time, the protective layer 509 on the surface of the airbag 508 fits with the inner wall of the vagina. Then the staff inserts the infusion needle 3 into the rat's vagina through the through hole 502 on the vaginal dilator shell 501, and then inserts it into the uterus from the cervical opening. The hand button 8 is pressed to discharge the medicine in the needle tube 1 through the infusion needle 3, thereby completing the injection and drug administration.

[0027] The above shows and describes the basic principle, main features and advantages of the utility model. Technical staff in this industry should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the utility model and are not used to limit the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection of the utility model is defined by the attached claims and their equivalents.

Claims

1. A disposable drug delivery device for rat uterine cavity, comprising a needle tube (1), characterized in that: The top of the needle tube (1) is fixedly connected to a needle seat (2), the top of the needle seat (2) is fixedly connected to an infusion needle (3), the bottom of the needle tube (1) is movably connected to a plunger (4), one side of the plunger (4) extends into the interior of the needle tube (1), the inner cavity of the needle tube (1) is slidably connected to the plunger (4), and a vaginal dilation component (5) is provided on the upper side of the needle tube (1).

2. The disposable rat uterine cavity drug delivery device according to claim 1, characterized in that: The vaginal dilation component (5) comprises a vaginal dilation shell (501), which is sleeved on the outside of the perfusion needle (3), and a through opening (502) is formed on the top of the vaginal dilation shell (501).

3. The disposable drug delivery device for rat uterine cavity according to claim 2, characterized in that: The inner side of the vaginal expansion shell (501) is fixedly connected to a support member (503), the inner end of the vaginal expansion shell (501) is provided with a gas delivery cavity (504), and the outer side of the vaginal expansion shell (501) is fixedly connected to a connecting pipe (506).

4. The disposable rat uterine cavity drug delivery device according to claim 3, characterized in that: A fixed end (507) is sleeved on one side of the outer side of the connecting tube (506), and an air bag (508) is fixedly connected to the side of the fixed end (507) away from the connecting tube (506).

5. The disposable rat uterine cavity drug delivery device according to claim 4, characterized in that: The connecting pipe (506) and the airbag (508) are fixedly connected, and a protective layer (509) is fixedly connected to the outer surface of the airbag (508).

6. The disposable rat uterine cavity drug delivery device according to claim 5, characterized in that: A rubber tube (6) is sleeved on the upper side of the outer side of the perfusion needle (3), a scale bar (7) is provided on the front surface of the needle tube (1), and a button (8) is fixedly connected to the bottom of the plunger (4).