Detection strip for macrolide antibiotics

Abstract

The utility model provides a detection strip for macrolide antibiotics. The detection strip comprises a lower shell, an upper shell and a test strip, a display groove and a detection opening are formed in the upper shell; a connecting sleeve is integrally formed in the upper shell; a connecting column is integrally formed at the position, corresponding to the connecting sleeve, in the lower shell, the upper shell and the lower shell are detachably connected through the connecting sleeve and the connecting column, a supporting assembly is arranged in the lower shell, and the test strip is movably arranged in the supporting assembly; a sealing structure is also arranged between the upper shell and the lower shell; the top of the upper shell is provided with a sealing film assembly used for covering the display groove and the detection opening. According to the utility model, the effect that the test strip is completely sealed by the upper shell and the lower shell when the test strip is not used in daily life is effectively achieved; the problems that the detection precision of the test strip is reduced and the test strip fails due to the contact between external humid air, carbon dioxide and suspended microorganisms and the test strip are avoided.

Description

Technical Field

[0001] The utility model relates to the field of antibiotic detection, in particular to a detection strip for macrolide antibiotics. Background Art

[0002] Macrolide antibiotics are an important class of antibacterial drugs, which are widely used in clinical treatment and have antibacterial activity against a variety of Gram-positive bacteria and some Gram-negative bacteria. With the widespread use of antibiotics, their residues have also received increasing attention. Therefore, the detection of macrolide antibiotics has become an important task in the fields of food safety, environmental monitoring and clinical research. At present, the detection methods of macrolide antibiotics mainly include chromatography, mass spectrometry, immunoassay and biosensors. These methods have their own advantages and disadvantages. For example, chromatography has high separation efficiency and sensitivity, but the operation is complicated; mass spectrometry has high accuracy, but the equipment is expensive; immunoassay has strong specificity, but may be affected by cross-reactions. Therefore, the development of rapid, simple and accurate macrolide antibiotic detection methods is still a current research hotspot.

[0003] Macrolide antibiotic test strips are a rapid detection tool based on immunochromatography technology; they use the binding reaction of specific antibodies and antigens to indicate the presence of antibiotics through color changes or signal intensity; test strips usually include sample pads, conjugate pads, nitrocellulose membranes, and absorbent paper. The sample pad is used to absorb and pretreat samples, the conjugate pad is coated with specific antibodies, and the nitrocellulose membrane is fixed with antigens and color-developing substances corresponding to the antibodies; when the antibiotics in the sample bind to the antibodies, the complex will move on the membrane and bind to the fixed antigens, resulting in a color reaction, thereby achieving rapid qualitative or semi-quantitative detection of antibiotics;

[0004] However, the reagents and materials in the test strips are often sensitive to humidity. Long-term exposure may cause the reagents to denature or become ineffective, thus affecting the accuracy of the test results. In addition, components such as oxygen and carbon dioxide in the air may affect the activity of antibodies, resulting in a decrease in the binding ability of antibodies to antigens, thereby reducing the detection sensitivity. Finally, microorganisms, dust and other pollutants in the air may adhere to the test strips, interfering with the antigen-antibody reaction and producing false positive or false negative results. Therefore, it is particularly important to improve the daily storage and sealing of macrolide antibiotic test strips. Utility Model Content

[0005] In order to solve the problem of convenient sealing and storage of rapid test cards for macrolide antibiotics in the prior art, the utility model provides a test strip for macrolide antibiotics;

[0006] The utility model provides a macrolide antibiotic test strip using the following technical solution:

[0007] A test strip for macrolide antibiotics, comprising a lower shell, an upper shell, and a test strip; a display slot and a test port are provided inside the upper shell; a connecting sleeve is integrally formed inside the upper shell; a connecting column is integrally formed inside the lower shell at a position corresponding to the connecting sleeve; the upper shell and the lower shell are detachably connected via the connecting sleeve and the connecting column; a supporting assembly is provided inside the lower shell, and the test strip is movably provided inside the supporting assembly; a sealing structure is also provided between the upper shell and the lower shell; a sealing film assembly for covering the display slot and the test port is provided on the top of the upper shell;

[0008] Furthermore, the support assembly includes a bracket and a test paper slot; the bottom of the lower housing is integrally formed with the bracket; the inside of the bracket is integrally formed with a test paper slot; the test paper strip is arranged in the test paper slot;

[0009] Furthermore, the outer side wall of the test strip slot is provided with a plurality of buckle slots for facilitating the removal of the test strips;

[0010] Further, the sealing structure includes a sealing strip, a sealing gasket, an inner plate, and a sealing groove; the inner bottom of the upper shell is integrally formed with the inner plate; a sealing groove is formed between the inner plate and the inner side wall of the upper shell; the inner bottom of the lower shell is integrally formed with a sealing strip; the top of the sealing strip is fixedly connected with a sealing gasket; the sealing strip and the sealing groove are used in conjunction with each other;

[0011] Furthermore, the outer side wall of the upper shell is also integrally formed with a plurality of buckles; the outer side wall of the lower shell is also integrally formed with the same number of buckles as the buckles at positions corresponding to the buckles; the buckles can be mutually engaged with the buckles to further fix the upper shell and the lower shell;

[0012] Furthermore, a water retaining strip is integrally formed on the top of the upper shell; the water retaining strip surrounds the outside of the display slot and the detection port; the sealing film assembly is arranged on the inner side of the water retaining strip;

[0013] Furthermore, the sealing film assembly includes a sealing film, a hot melt line, and an easy-pull strip; the sealing film covers the surface of the display slot and the detection port, and the sealing film forms a hot melt line at the edge by hot pressing; the edge of the sealing film is also integrally formed with an easy-pull strip;

[0014] Furthermore, a suction cup is installed at the bottom of the lower shell.

[0015] In summary, the beneficial effects of the utility model are:

[0016] The utility model effectively achieves the effect that the test strip is completely sealed by the upper shell and the lower shell when not in use daily by adding an upper shell, a lower shell, a sealing structure and a sealing film assembly; the utility model further fixes the upper shell and the lower shell by the buckle clamping the clamping block according to its own elasticity when the upper shell and the lower shell are closed; and the sealing strip is inserted into the sealing groove formed between the inner layer plate and the inner side wall of the lower shell during the installation of the upper shell and the lower shell, and the sealing strip completely resists the sealing gasket against the bottom of the sealing groove, and the sealing degree between the upper shell and the lower shell can be improved to the greatest extent through such a sealing structure, and the test strip is effectively sealed in the upper shell and the lower shell through such a technology to prevent the external humid air, carbon dioxide and suspended microorganisms from contacting the test strip, resulting in problems such as reduced detection accuracy and failure of the test strip; when in use, pull the easy-pull strip to tear off the sealing film along the hot melt line to start the test; drop the detection reagent directly into the detection port, and observe the result displayed by the test strip in the display slot. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 This is a schematic diagram of the internal structure of the lower shell of the utility model;

[0019] Figure 3 This is a schematic diagram of the internal structure of the upper shell of the utility model;

[0020] Figure 4 This is a schematic diagram of the overall structure of the lower housing of the utility model without the test strip;

[0021] Figure 5 For this utility model Figure 1 A magnified schematic diagram of part A;

[0022] Figure 6 For this utility model Figure 4 A magnified schematic diagram of part B;

[0023] Figure 7 For this utility model Figure 3 A magnified schematic diagram of part C;

[0024] Figure 8 It is a schematic diagram of the bottom structure of the lower shell of the utility model.

[0025] As shown in the figure: 1-lower shell, 11-connecting column, 12-sealing strip, 13-sealing gasket, 2-upper shell, 21-display slot, 22-detection port, 23-water retaining strip, 24-connecting sleeve, 25-inner plate, 26-sealing slot, 3-bracket, 31-test paper slot, 32-buckle slot, 4-test paper strip, 5-card block, 51-buckle, 6-sealing film, 61-hot melt line, 62-pull strip, 7-suction cup. DETAILED DESCRIPTION

[0026] The following is combined with Figure 1-8 The utility model is further described in detail:

[0027] The utility model embodiment discloses a test strip for macrolide antibiotics, such as Figure 1 , Figure 2 , Figure 3 As shown, a test strip for macrolide antibiotics comprises a lower shell 1, an upper shell 2, and a test strip 4; a display slot 21 and a test port 22 are provided inside the upper shell 2; a connecting sleeve 24 is integrally formed inside the upper shell 2; a connecting column 11 is integrally formed inside the lower shell 1 at a position corresponding to the connecting sleeve 24, the upper shell 2 and the lower shell 1 are detachably connected through the connecting sleeve 24 and the connecting column 11, a supporting assembly is provided inside the lower shell 1, and the test strip 4 is movably provided inside the supporting assembly; a sealing structure is also provided between the upper shell 2 and the lower shell 1; a sealing structure for connecting the display slot 21 and the test port 22 is provided at the top of the upper shell 2 2 covered sealing film assembly; in this embodiment, the upper shell 2 and the lower shell 1 are assembled between the connecting column 11 and the connecting sleeve 24, and the test strip 4 is suspended by the supporting assembly so that it fits the detection port 22 and the display slot 21 of the upper shell 2, which is convenient for the detection reagent to drip onto the test strip 4, and the sealing structure provided between the upper shell 2 and the lower shell 1 can increase the sealing between the upper shell 2 and the lower shell 1, combined with the covering seal of the sealing film assembly, the test strip 4 can be completely sealed inside the upper shell 2 and the lower shell 1, avoiding the test strip 4 from being exposed to the air for a long time to reduce the detection accuracy, and can extend the storage time and service life of the test strip;

[0028] like Figure 3 As shown, the support assembly includes a bracket 3 and a test paper slot 31; the bracket 3 is integrally formed at the bottom of the lower housing 1; the test paper slot 31 is integrally formed inside the bracket 3; the test paper strip 4 is arranged in the test paper slot 31; in this embodiment, the bracket 3 and the test paper slot 31 can suspend the test paper strip 4 too high, and the test paper strip 4 can be close to the inner wall of the upper housing 2, so that a part of the test paper strip 4 is exposed through the detection port 22 and the display slot 21, which provides convenience for the detection of macrolide antibiotics;

[0029] like Figure 4As shown, the outer wall of the test paper slot 31 is provided with a plurality of buckle slots 32 for facilitating the removal of the test paper strip 4; in this embodiment, during assembly, the installer needs to place the test paper strip 4 in the test paper slot 31, and the buckle slots 32 can help the installer to take the test paper strip 4 out of the test paper slot 31 at any time for adjustment;

[0030] like Figure 6 , Figure 7 As shown, the sealing structure includes a sealing strip 12, a sealing gasket 13, an inner plate 25, and a sealing groove 26; the inner bottom of the upper shell 2 is integrally formed with the inner plate 25; a sealing groove 26 is formed between the inner plate 25 and the inner side wall of the upper shell 2; the inner bottom of the lower shell 1 is integrally formed with the sealing strip 12; the top of the sealing strip 12 is fixedly connected with the sealing gasket 13; the sealing strip 12 and the sealing groove 26 are used in conjunction with each other; in this embodiment, the sealing strip 12 will be inserted into the sealing groove 26 formed between the inner plate 25 and the inner side wall of the lower shell 1 during the installation of the upper shell 2 and the lower shell 1, and the sealing strip 12 will completely resist the sealing gasket 13 from the bottom of the sealing groove 26, and such a sealing structure can maximize the degree of sealing between the upper shell 2 and the lower shell 1;

[0031] In addition, it is worth noting that the sealing pad 13 can be made of rubber or silicone in a flexible material;

[0032] like Figure 5 As shown, the outer wall of the upper shell 2 is also integrally formed with a plurality of buckles 51; the outer wall of the lower shell 1 is also integrally formed with the same number of buckles 5 as the buckles 51 at the position corresponding to the buckle 5; the buckle 5 can be mutually engaged with the buckle 51 to further fix the upper shell 2 and the lower shell 1; in this embodiment, when the upper shell 2 and the lower shell 1 are installed, the connecting column 11 is inserted into the interior of the connecting sleeve 24, and when the upper shell 2 and the lower shell 1 are closed, the buckle 51 will clamp the block 5 according to its own elasticity to further fix the upper shell 2 and the lower shell 1, so as to prevent the upper shell 2 and the lower shell 1 from loosening and opening;

[0033] like Figure 1 As shown, a water retaining bar 23 is integrally formed on the top of the upper shell 2; the water retaining bar 23 surrounds the outer side of the display slot 21 and the detection port 22; the sealing film assembly is arranged on the inner side of the water retaining bar 23; in this embodiment, the water retaining bar 23 can prevent the detection reagent from overflowing from the detection port 22 and flowing onto the desktop when too much detection reagent is squeezed in;

[0034] like Figure 1As shown, the sealing film assembly includes a sealing film 6, a hot melt line 61, and an easy-pull strip 62; the sealing film 6 covers the surface of the display slot 21 and the detection port 22, and the sealing film 6 forms a hot melt line 61 at the edge by heat pressing; the edge of the sealing film 6 is also integrally formed with an easy-pull strip 62; in this embodiment, the sealing film assembly is to cover the detection port 22 and the display slot 21 with the sealing film 6, further preventing the test strip 4 from contacting the air, and to fit the sealing film 6 to the upper shell 2 by heat pressing. When the utility model needs to be used for detection, it is only necessary to pull the easy-pull strip 62 to tear off the sealing film 6 along the hot melt line 61 to start the detection;

[0035] like Figure 8 As shown, a suction cup 7 is installed at the bottom of the lower shell 1; in this embodiment, the suction cup 7 can firmly fix the utility model on the detection platform.

[0036] The implementation principle of the embodiment of the utility model is:

[0037] During the assembly of the utility model, the installer inserts the connecting column 11 into the interior of the connecting sleeve 24. When the upper shell 2 and the lower shell 1 are closed, the buckle 51 will clamp the block 5 according to its own elasticity to further fix the upper shell 2 and the lower shell 1. In addition, the sealing strip 12 will be inserted into the sealing groove 26 formed between the inner plate 25 and the inner side wall of the lower shell 1 during the installation of the upper shell 2 and the lower shell 1, and the sealing strip 12 will completely resist the sealing gasket 13 from the bottom of the sealing groove 26. Through such a sealing structure, the sealing degree between the upper shell 2 and the lower shell 1 can be improved to the greatest extent.

[0038] When the utility model is used, the user only needs to pull the pull strip 62 to tear off the sealing film 6 along the hot-melt line 61 to start the test; the test reagent is directly dropped into the test port 22 and the result displayed by the test strip 4 in the display slot 21 is observed.

[0039] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. The various components mentioned in the utility model are common technologies in the existing field. The technicians in this industry should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only to illustrate the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model will have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A test strip for macrolide antibiotics, comprising a lower shell (1), an upper shell (2), and a test strip (4); characterized in that: The upper shell (2) is provided with a display slot (21) and a detection port (22); a connecting sleeve (24) is integrally formed inside the upper shell (2); a connecting column (11) is integrally formed inside the lower shell (1) at a position corresponding to the connecting sleeve (24); the upper shell (2) and the lower shell (1) are detachably connected via the connecting sleeve (24) and the connecting column (11); a supporting assembly is provided inside the lower shell (1), and the test strip (4) is movably arranged inside the supporting assembly; a sealing structure is also provided between the upper shell (2) and the lower shell (1); and a sealing film assembly for covering the display slot (21) and the detection port (22) is provided at the top of the upper shell (2).

2. A macrolide antibiotic test strip according to claim 1, characterized in that The support assembly comprises a bracket (3) and a test paper slot (31); the bracket (3) is integrally formed at the bottom of the interior of the lower housing (1); the test paper slot (31) is integrally formed inside the bracket (3); and the test paper strip (4) is arranged in the test paper slot (31).

3. A macrolide antibiotic test strip according to claim 2, characterized in that The outer side wall of the test paper slot (31) is provided with a plurality of buckle slots (32) for facilitating the removal of the test paper strips (4).

4. A macrolide antibiotic test strip according to claim 1, characterized in that The sealing structure comprises a sealing strip (12), a sealing gasket (13), an inner plate (25), and a sealing groove (26); the inner bottom of the upper shell (2) is integrally formed with the inner plate (25); a sealing groove (26) is formed between the inner plate (25) and the inner side wall of the upper shell (2); the inner bottom of the lower shell (1) is integrally formed with a sealing strip (12); the top of the sealing strip (12) is fixedly connected with the sealing gasket (13); the sealing strip (12) and the sealing groove (26) are used in conjunction with each other.

5. A macrolide antibiotic test strip according to claim 1, characterized in that The outer side wall of the upper shell (2) is also integrally formed with a plurality of buckles (51); the outer side wall of the lower shell (1) is also integrally formed with the same number of buckles (5) as the buckles (51) at positions corresponding to the buckles (5); the buckles (5) can be mutually engaged with the buckles (51) to achieve further fixation between the upper shell (2) and the lower shell (1).

6. A macrolide antibiotic test strip according to claim 1, characterized in that A water retaining strip (23) is integrally formed on the top of the upper shell (2); the water retaining strip (23) surrounds the outside of the display slot (21) and the detection port (22); and the sealing film assembly is arranged on the inside of the water retaining strip (23).

7. A macrolide antibiotic test strip according to claim 6, characterized in that The sealing film assembly comprises a sealing film (6), a hot melt line (61), and an easy-pull strip (62); the sealing film (6) covers the surface of the display slot (21) and the detection port (22), and the sealing film (6) forms a hot melt line (61) at the edge by heat pressing; the edge of the sealing film (6) is also integrally formed with an easy-pull strip (62).

8. A macrolide antibiotic test strip according to claim 1, characterized in that The bottom of the lower shell (1) is equipped with.

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