Cold hammer mechanism and freezing slicer

Abstract

The cold hammer mechanism comprises a cold table, a driving module and a cold hammer, the driving module is located above the cold table and comprises a guide rail, a moving body and a swing arm, the guide rail is arranged in the circumferential direction of the cold table, the moving body is connected to the guide rail in a sliding mode, one end of the swing arm is rotationally connected to the moving body, and the other end of the swing arm is connected to the cold table. The cold hammer is located above the cold table and is slidably connected to the end, away from the moving body, of the swing arm in the vertical direction; the freezing slicer comprises the cold hammer mechanism. Due to the fact that the guide rail is arranged in the circumferential direction of the cooling table, the moving body can move to different positions of the periphery of the cooling table along the guide rail, the swing arm synchronously moves along with the moving body and can rotate relative to the moving body while moving, and therefore the cold hammer is driven to different positions of the cooling table, and the moving range of the cold hammer is large. And the freezing requirements of samples at different positions on the cold table can be met.

Description

Technical Field

[0001] The utility model relates to the technical field of pathological tissue sections, in particular to a cold hammer mechanism and a freezing microtome. Background Art

[0002] Currently, pathological diagnosis in clinical surgery requires sampling of the lesion sample first, then slicing the sample using a freezing microtome, and then performing pathological analysis on the slice. The sample needs to be frozen before slicing. In related technologies, the sample is usually placed on a sample tray, and a cold hammer is in contact with the top of the sample. The sample tray and the cold hammer respectively conduct cold sources to the sample from the bottom and top of the sample to achieve rapid freezing of the sample. However, the range of motion of the cold hammer is limited and cannot meet the freezing requirements of samples located at different positions on the sample tray. Summary of the invention

[0003] The utility model aims to solve at least one of the technical problems existing in the prior art. To this end, the utility model proposes a cold hammer mechanism, which has a large range of motion and can meet the freezing requirements of samples at different positions on the cold table.

[0004] The utility model also provides a freezing microtome with the cold hammer mechanism.

[0005] According to the first aspect of the present invention, the cold hammer mechanism comprises:

[0006] A cold stage for placing samples to be frozen;

[0007] A driving module is located above the cold stage, and comprises a guide rail, a moving body and a swing arm, wherein the guide rail is arranged along the circumference of the cold stage, the moving body is slidably connected to the guide rail, and one end of the swing arm is rotatably connected to the moving body;

[0008] The cold hammer is located above the cold platform and is vertically slidably connected to an end of the swing arm away from the moving body.

[0009] The cold hammer mechanism according to the embodiment of the utility model has at least the following beneficial effects:

[0010] In this embodiment, the guide rail is arranged along the circumference of the cold table, and the movable body can move along the guide rail to different positions on the periphery of the cold table. The swing arm moves synchronously with the movable body and can rotate relative to the movable body while moving, thereby driving the cold hammer to different positions of the cold table. The cold hammer has a large range of motion and can meet the freezing requirements of samples at different positions on the cold table.

[0011] According to some embodiments of the present invention, the guide rail is annular and is arranged around the outer periphery of the cold stage;

[0012] Alternatively, the guide rails are distributed on one side of the cold stage.

[0013] According to some embodiments of the present invention, the cold stage has a first side and a second side opposite to each other in a first direction, the guide rail is arranged on the first side, the cold stage is provided with a plurality of cold zones, each of the cold zones can be used to place a sample to be frozen, the cold zone closest to the second side is defined as an edge cold zone, the farthest position of the cold hammer relative to the first side is the farthest end, and the farthest end is located on a side of the edge cold zone facing away from the first side;

[0014] and / or,

[0015] The cold zone closest to the first side is defined as the critical cold zone, the closest position of the cold hammer relative to the first side is defined as the closest end, and the closest end is located on the side of the critical cold zone facing away from the second side.

[0016] According to some embodiments of the present invention, the rotation angle of the swing arm is not less than 180°.

[0017] According to some embodiments of the utility model, the cold hammer includes a rod body and a weight, the rod body is connected to one end of the swing arm, the weight is detachably connected to the lower end of the rod body, and the bottom surface of the weight is used to contact the sample;

[0018] Alternatively, the cold hammer includes a rod body and a plurality of weights, wherein the rod body is slidably connected to one end of the swing arm, the plurality of weights are stacked and detachably connected to the lower end of the rod body, and the bottom surface of the bottom layer of the weights is used to contact the sample.

[0019] According to some embodiments of the present invention, the cold hammer further includes a handle connected to the top of the rod body.

[0020] According to some embodiments of the utility model, the cold hammer includes a rod body, the swing arm is provided with a mounting hole penetrating vertically, and the mounting hole has an opening penetrating to the side of the swing arm, and the opening is used for the rod body to pass through and be installed in the mounting hole.

[0021] According to some embodiments of the utility model, the cold hammer further includes a guide sleeve, the rod body is vertically slidably connected in the guide sleeve, the guide sleeve is vertically inserted into the mounting hole and can block the opening.

[0022] According to the second aspect of the present invention, the cold hammer mechanism is characterized by comprising:

[0023] A cold stage for placing samples to be frozen;

[0024] A driving module is located above the cold platform, the driving module comprises a first slide rail, two second slide rails arranged side by side and a sliding body, the two second slide rails are arranged on opposite sides of the cold platform, the extension directions of the first slide rail and the second slide rail intersect, the two ends of the first slide rail are respectively slidably connected to the two second slide rails, and the sliding body is slidably connected to the first slide rail;

[0025] The cold hammer is located above the cold stage and is vertically slidably connected to the sliding body.

[0026] The cold hammer mechanism according to the embodiment of the utility model has at least the following beneficial effects:

[0027] In this embodiment, while the sliding body slides along the first slide rail, it can move along the second slide rail synchronously following the first slide rail, so that the cold hammer can move in two directions at the same time. The cold hammer has a large range of motion and can freeze samples located at different positions on the cold table.

[0028] A freezing microtome according to a third aspect of the present invention comprises:

[0029] A cold hammer mechanism according to the first or second aspect;

[0030] The slicing mechanism is used to slice the frozen samples.

[0031] Additional aspects and advantages of the present invention will be given in part in the following description, and in part will become apparent from the following description, or will be learned through the practice of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] The present invention is further described below with reference to the accompanying drawings and embodiments, wherein:

[0033] Figure 1 It is a schematic diagram of an embodiment of the cold hammer mechanism of the utility model;

[0034] Figure 2 for Figure 1 Schematic diagram of the intercooler hammer and drive module;

[0035] Figure 3 It is a schematic diagram of the cooperation between the cold hammer mechanism and the inner wall of the freezing microtome;

[0036] Figure 4 is a schematic diagram of another embodiment of a guide rail;

[0037] Figure 5 for Figure 1 Explosion diagram of the intercooler hammer mechanism;

[0038] Figure 6 It is a schematic diagram of another embodiment of the cold hammer mechanism.

[0039] Reference numerals:

[0040] Cold hammer mechanism 100, cold stage 110, cold zone 111, first side 112, second side 113, first end 114, second end 115, drive module 120, guide rail 121, moving body 122, moving part 1221, connecting part 1222, avoidance groove 1223, arc surface 1224, swing arm 123, mounting hole 1231, opening 1232, open rotating shaft 124, bearing 125, sleeve 126, first slide rail 127, second slide rail 128, sliding body 129, cold hammer 130, rod body 131, notch 1311, mounting part 1312, weight 132, plug hole 1321, plug groove 1322, guide sleeve 133, handle 134;

[0041] Shell 200. DETAILED DESCRIPTION

[0042] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0043] In the description of the present invention, it should be understood that descriptions involving orientation, such as up, down, front, back, left, right, etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0044] In the description of the present utility model, "several" means more than one, "many" means more than two, "greater than", "less than", "exceed" etc. are understood to exclude the number itself, and "above", "below", "within" etc. are understood to include the number itself. If there is a description of "first" or "second", it is only used to distinguish the technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0045] In the description of the present invention, unless otherwise clearly defined, terms such as setting, installing, connecting, etc. should be understood in a broad sense, and technicians in the relevant technical field can reasonably determine the specific meanings of the above terms in the present invention based on the specific content of the technical solution.

[0046] In the description of the utility model, the description with reference to the terms "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0047] The embodiment of the present utility model provides a cold hammer mechanism 100, referring to Figure 1 and Figure 2 The cold hammer mechanism 100 includes a cold table 110, a driving module 120 and a cold hammer 130. The cold table 110 is used to place the sample to be frozen. The top surface of the cold table 110 provides a flat placement plane for the sample. A cold source is arranged at the bottom of the cold table 110. The cold source contacts the cold table 110 and transfers cold energy to the cold table 110. The cold energy is transferred to the sample through the cold table 110, so that the sample is frozen. The cold hammer 130 is located above the cold table 110, and is used to contact the top of the sample and provide a downward pressing force to the sample, so that the top surface of the sample is in full contact with the cold hammer 130 and the bottom surface of the sample is in full contact with the cold table 110, so as to achieve rapid freezing of the sample.

[0048] The cold hammer 130 is connected to the driving module 120 and moves under the drive of the driving module 120 to contact the samples placed at different positions of the cold stage 110. The driving module 120 is located above the cold stage 110. The driving module 120 includes a guide rail 121, a moving body 122 and a swing arm 123. The guide rail 121 is arranged along the circumference of the cold stage 110. The moving body 122 is slidably connected to the guide rail 121 and moves around the circumference of the cold stage 110 under the guidance of the guide rail 121. One end of the swing arm 123 is rotatably connected to the moving body 122. While the swing arm 123 rotates relative to the moving body 122, it can move synchronously with the movement of the moving body 122 along the guide rail 121. The cold hammer 130 is connected to the end of the swing arm 123 away from the moving body 122 along the vertical sliding direction, so that the cold hammer 130 is far away from the guide rail 121 to a large extent, and can follow the movement of the moving body 122, and move to a position of the cold table 110 far away from the guide rail 121, so that the cold hammer 130 has a larger range of movement; in addition, because the cold hammer 130 can move vertically relative to the swing arm 123, after the sample is placed on the cold table 110, the cold hammer 130 descends, contacts and presses the top of the sample, and the cold hammer 130 and the cold table 110 are combined to freeze the sample. After the sample is frozen, the cold hammer 130 is lifted up and away from the sample, and the sample can be removed from the cold table 110.

[0049] It can be understood that since the guide rail 121 is arranged along the circumference of the cold table 110, the movable body 122 can move along the guide rail 121 to different positions of the cold table 110, and the swing arm 123 moves synchronously with the movable body 122 and can rotate relative to the movable body 122 while moving, thereby driving the cold hammer 130 to different positions of the cold table 110. The cold hammer 130 has a large range of motion and can meet the freezing requirements of samples at different positions on the cold table 110.

[0050] The sliding connection between the moving body 122 and the guide rail 121 is not limited to that one of the moving body 122 and the guide rail 121 is provided with a slide groove, and the other is provided with a slider, the slider slides in the slide groove, or the groove wall of the slide groove moves along the extension direction of the slider; or, the guide rail 121 is provided with a moving channel on the side facing the cold table 110, and the end of the moving body 122 is provided with a ball joint, and the end of the moving body 122 is hinged in the moving channel and can move along the moving channel, so that the moving body 122 can be turned in the guide rail 121, so that the moving body 122 moves to different sides of the cold table 110.

[0051] In one embodiment, the extension direction of the guide rail 121 is parallel to the upper plane of the cold stage 110, and the rotation axis of the swing arm 123 is perpendicular to the upper plane of the cold stage 110. The swing arm 123 will not generate vertical displacement when following the movement of the moving body 122 and rotating relative to the moving body 122, so that the cold hammer 130 can always maintain a certain distance between it and the cold stage 110 to avoid interference with other components or samples.

[0052] It should be noted that if Figure 3 As shown, the guide rail 121 is arranged along the circumference of the cold stage 110, and the guide rail 121 can be directly installed using the inner side wall of the cryostat without the need to set up other additional installation structures, making the installation of the cold hammer mechanism 100 more convenient. Furthermore, the guide rail 121 is arranged outside the cold stage 110 so that the guide rail 121 avoids the space above the cold stage 110, and the swing arm 123 can be moved close to the guide rail 121 by rotating to avoid the space above the cold stage 110, so as to facilitate the placement and removal of samples on the cold stage 110.

[0053] The guide rail 121 is arranged along the circumference of the cold stage 110, which means that the guide rail 121 has a tendency to extend along the outer contour of the cold stage 110. The guide rail 121 can be arranged on one side of the cold stage 110, or around the entire outer circumference of the cold stage 110. Specifically, in one embodiment, Figure 4 As shown, the guide rail 121 is annular and is arranged around the outer periphery of the cold table 110. The moving body 122 can move along the guide rail 121 to any position on the circumference of the cold table 110, and then drive the cold hammer 130 to different areas above the cold table 110 through the swing arm 123. The cold hammer 130 has a large range of motion.

[0054] In another embodiment, if Figure 1 and Figure 3 As shown, the guide rail 121 is distributed on one side of the cold table 110, and the swing arm 123 is connected to the side of the moving body 122 facing the other side opposite to the guide rail 121. The moving body 122 can move along the guide rail 121 to the opposite ends of the cold table 110, and the swing arm 123 moves with the movement of the moving body 122 and rotates relative to the moving body 122 to drive the cold hammer 130 to different positions above the cold table 110, so that the cold hammer 130 has a larger range of movement. The guide rail 121 is set on one side of the cold table 110, and the structure of the driving module 120 is simpler, and the guide rail 121 can be directly installed using the side wall of the freezing microtome, and there is no need to set other structures for the guide rail 121 to be installed in the freezing microtome.

[0055] The projection of the cold table 110 in the horizontal plane is set to be a rectangle, a circle or other shapes. In one embodiment of the utility model, the projection of the cold table 110 in the horizontal plane is set to be a rectangle, and the guide rail 121 is set on the side of the rectangle with the long side. The swing arm 123 does not need to be set to a large length, so that the cold hammer 130 can be moved to the edge of the two long sides of the cold table 110, and the probability of the cold hammer 130 shaking or overturning relative to the swing arm 123 during the movement can be reduced. It can be understood that the guide rail 121 extends from one end of the cold table 110 to the other end along the length direction of the cold table 110 to increase the moving range of the moving body 122, so that the cold hammer 130 can move to the edge position of the two ends of the cold table 110.

[0056] Reference Figure 1 A plurality of cold zones 111 are arranged in an array on the cold stage 110, and each cold zone 111 can be used to place a sample; further, a downwardly recessed groove is provided on the top of the cold stage 110, and each groove forms a cold zone 111, and the groove wall of the groove limits the sample to prevent the sample from being displaced by the pressure of the cold hammer 130 during the freezing process.

[0057] In the case where the guide rail 121 is disposed on one side of the cold stage 110, the cold stage 110 has a first side 112 and a second side 113 that are opposite to each other in a first direction, the guide rail 121 is disposed on the first side 112, one end of the swing arm 123 is rotatably connected to the side of the moving body 122 facing the second side 113, and the other end of the swing arm 123 is connected to the cold hammer 130; the cold zone 111 closest to the second side 113 is defined as the edge cold zone, the farthest position of the cold hammer 130 relative to the first side 112 is the farthest end, and the farthest end is located on the side of the edge cold zone that is away from the first side 112, so that the cold hammer 130 can move to the cold zone 111 located at the edge position of the second side 113, and the samples located in different cold zones 111 can all contact the cold hammer 130.

[0058] It is understandable that when the swing arm 123 is rotated to be perpendicular to the guide rail 121, the cold hammer 130 is at the farthest position from the guide rail 121, and the cold zone 111 located at the edge of the second side 113 of the cold platform 110 is farthest from the guide rail 121. When the cold hammer 130 is at the farthest end, it is located on the side of the edge cold zone facing away from the first side 112. On the one hand, the cold hammer 130 can be moved to the farthest cold zone 111 to freeze the sample located at the edge. On the other hand, the length of the swing arm 123 and the overall volume of the cold hammer mechanism 100 are minimized to the greatest extent, thereby reducing the risk of pendulum shaking or overturning due to the excessive length of the swing arm 123.

[0059] Further, the cold zone 111 closest to the first side 112 is defined as the critical cold zone, and the closest position of the cold hammer 130 relative to the guide rail 121 is the closest end, which is located on the side of the critical cold zone facing away from the second side 113, and the cold hammer 130 can freeze the sample in the cold zone 111 adjacent to the first side 112. Therefore, when the guide rail 121 is set on one side of the cold zone 111, by setting the moving body 122 to move along the guide rail 121, and the swing arm 123 swinging relative to the moving body 122, the cold hammer 130 can be moved to the second side 113 far from the guide rail 121 and the first side 112 close to the guide rail 121, and the range of movement of the cold hammer 130 can cover all areas of the cold table 110.

[0060] It is understandable that when the swing arm 123 is arranged parallel to the guide rail 121 , the cold hammer 130 is closest to the guide rail 121 , and at this time, the cold hammer 130 is located closest to the first side 112 .

[0061] In one embodiment, the swing arm 123 is set to rotate at an angle of not less than 180 degrees, so that the swing arm 123 can drive the cold hammer 130 to move to the end position in the length direction of the cold stage 110 by swinging at a large angle to freeze the sample in the cold zone 111 located at the end edge. Taking the rotation angle of the swing arm 123 as 180° as an example, the two ends of the cold stage 110 in the length direction are defined as the first end 114 and the second end 115 respectively. When the swing arm 123 is parallel to the guide rail 121 and the cold hammer 130 is toward the first end 114, the rotation angle of the swing arm 123 is zero. When the swing arm 123 rotates toward the second end 115 to be perpendicular to the guide rail 121, the rotation angle of the swing arm 123 is 90°. At this time, the cold hammer 130 is farthest from the first side 112. When the swing arm 123 continues to rotate toward the second end 115 to be parallel to the guide rail 121, the rotation angle of the swing arm 123 is 180°. When the swing arm 123 is parallel to the guide rail 121, the distance between the cold hammer 130 and the first side 112 is shortest.

[0062] It can be understood that when the swing arm 123 swings to the side where the cold hammer 130 is located on the first end 114 of the moving body 122, the cold hammer 130 can freeze the samples in the cold zone 111 at the first end 114 of the cold table 110; when the swing arm 123 swings to the side where the cold hammer 130 is located on the second end 115 of the moving body 122, the cold hammer 130 can freeze the samples in the cold zone 111 at the second end 115 of the cold table 110, so that the cold hammer 130 can take into account the freezing needs of the samples located at the end positions of the cold table 110.

[0063] Of course, when the rotation angle of the swing arm 123 is greater than 180°, the swing arm 123 can expand the range of motion of the cold hammer 130 by rotating at a large angle; in addition, when the rotation angle of the swing arm 123 increases, the length of the swing arm 123 can be reduced, so that the cold hammer 130 can freeze samples at different positions and reduce the swing torque of the swing arm 123, thereby reducing the shaking of the cold hammer 130 when it is moved.

[0064] Reference Figure 5 The moving body 122 includes a moving part 1221 and a connecting part 1222 that are connected to each other. The moving part 1221 is slidably connected to the guide rail 121. The moving part 1221 protrudes away from the guide rail 121 relative to the connecting part 1222. An avoidance groove 1223 is provided at one end of the connecting part 1222 that is away from the moving part 1221. One end of the swing arm 123 is rotatably connected to the connecting part 1222, and the end of the swing arm 123 is located in the avoidance groove 1223, so that the connection between the swing arm 123 and the moving body 122 is more compact, and the avoidance groove 1223 can avoid the swing arm 123 when the swing arm 123 rotates toward the guide rail 121, so that the swing arm 123 has a larger rotation angle.

[0065] Specifically, the avoidance groove 1223 can be set at the bottom or top of the connecting part 1222. Taking the avoidance groove 1223 being set at the bottom of the connecting part 1222 as an example, the swing arm 123 is rotatably connected to the groove wall at the top of the avoidance groove 1223, and the groove wall of the avoidance groove 1223 facing away from the guide rail 121 has an arc surface 1224 protruding away from the guide rail 121. The arc surface 1224 can avoid the guide rail 121 when the swing arm 123 rotates toward the guide rail 121.

[0066] The driving module 120 further includes a rotating shaft 124, and the swing arm 123 is rotationally connected to the moving body 122 via the rotating shaft 124. Further, the driving module 120 further includes a bearing 125 and a sleeve 126, both of which are sleeved on the outside of the rotating shaft 124, and the bearing 125 and at least part of the sleeve 126 are accommodated in the inside of the swing arm 123. By providing the bearing 125 and the sleeve 126, the swing arm 123 is vertically matched with the moving body 122 and is rotationally connected.

[0067] The cold hammer 130 includes a rod body 131 and a weight 132. The rod body 131 is connected to one end of the swing arm 123 and is inserted into the interior of the swing arm 123. The rod body 131 can move vertically relative to the swing arm 123. The weight 132 is connected to the lower end of the rod body 131. The weight 132 can move up and down with the rod body 131 to be lifted or dropped. The provision of the weight 132 can make the cold hammer 130 as a whole have a certain weight. The weight 132 can contact the top of the sample and press the sample under the action of its own gravity, so that the sample is frozen under the combined action of the cold hammer 130 and the cold stage 110.

[0068] In one embodiment, one end of the swing arm 123 has a through hole that passes through the upper and lower parts. The rod body 131 is inserted into the through hole and can move up and down in the through hole. The through hole guides the movement of the rod body 131 to prevent the rod body 131 from shaking during the up and down movement. The rod 131 can fall freely vertically under the guidance of the inner wall of the through hole, so that the weight 132 can cover the sample on the cold platform 110.

[0069] The swing arm 123 is provided with a mounting hole 1231 which penetrates vertically, and the mounting hole 1231 has an opening 1232 which penetrates to the side of the swing arm 123, and the opening 1232 is used for the rod body 131 to pass through and be installed in the mounting hole 1231. That is, the rod body 1231 can enter the mounting hole 1231 from the side of the swing arm 123 through the opening 1232. In this case, the weight 132 can be installed on the rod body 131 in advance and assembled with the swing arm 123 together, and there is no need to install the weights 132 one by one after the rod body 131 is penetrated in the mounting hole 1231, and the assembly of the cold hammer 130 and the cold hammer 130 and the swing arm 123 is more convenient.

[0070] Further, such as Figure 1 and Figure 5As shown, the cold hammer 130 also includes a guide sleeve 133, and the rod body 131 is vertically slidably connected in the guide sleeve 133. The guide sleeve 133 is vertically inserted into the mounting hole 1231 and can block the opening 1232 to prevent the rod body 131 from detaching from the swing arm 123 from the opening 1232 after the cold hammer 130 and the swing arm 123 are assembled. Specifically, the rod body 131 is slidably connected with the guide sleeve 133, and the weight 132 is installed at one end of the rod body 131, so that the rod body 131 and the guide sleeve 133 slide relative to each other, so as to adjust the relative position of the rod body 131 and the guide sleeve 133, so that the guide sleeve 133 avoids the opening 1232 and is located above or below the opening 1232. After the rod body 131 is inserted into the mounting hole 1231 through the opening 1232, the guide sleeve 133 is pushed upward or downward, so that the guide sleeve 133 is vertically inserted into the mounting hole 1231 from above or below the mounting hole 1231, and the opening 1232 is blocked, thereby completing the assembly of the cold hammer 130 and the swing arm 123. At this time, the rod body 131 can only slide vertically relative to the guide sleeve 133, and cannot be separated from the swing arm 123 through the opening 1232, thereby preventing the cold hammer 130 from overturning.

[0071] Furthermore, at least part of the guide sleeve 133 is vertically inserted into one end of the swing arm 123, and at least part of the guide sleeve 133 protrudes vertically relative to the swing arm 123. Since the guide sleeve 133 has a certain length in the vertical direction, the contact area between the guide sleeve 133 and the rod body 131 is large, which can provide stable guidance for the rod body 131 and reduce the risk of overturning of the rod body 131; and, the stable movement of the rod body 131 does not need to rely on the vertical thickness of the swing arm 123, so the structure of the swing arm 123 can be thinned and the dead weight of the swing arm 123 can be reduced.

[0072] It is understandable that the guide sleeve 133 may protrude to one side of the swing arm 123 in the vertical direction, or both ends of the guide sleeve 133 may protrude to two opposite sides of the swing arm 123 in the vertical direction, so as to further increase the length of the guide sleeve 133 .

[0073] The weight 132 is detachably connected to the lower end of the rod 131, so as to facilitate the replacement of the weight 132 and the assembly with the rod 131; for example, when the cold hammer 130 is assembled with the swing arm 123, the weight 132 is first installed on the lower end of the rod 131, and then the rod 131 is inserted into the swing arm 123; or, when a weight 132 with a different mass needs to be replaced, the original weight 132 is removed and the new weight 132 is reinstalled on the lower end of the rod 131; or, the weight 132 is directly disassembled and installed on the rod 131 to increase or decrease the number of weights 132. The detachable connection between the weight 132 and the rod 131 is not limited to threaded connection, plug-in connection, etc.

[0074] In one embodiment, multiple weights 132 are provided. By increasing or decreasing the number of weights 132 and combining weights 132 of different weights, the total weight of the weights 132 in the cold hammer 130 can be adjusted to meet the requirements of covering different types of samples and prevent the samples from being crushed or damaged. Furthermore, the bottom of the weight 132 located at the bottom has a plane, and the plane of the bottom can contact the top of the sample, so that there is a larger contact area between the weight 132 and the sample, avoiding the sample from being crushed by concentrated force at a certain point. Multiple weights 132 are all threadedly connected to the rod body 131 and sleeved on the outside of the rod body 131, and multiple weights 132 are arranged in a vertical stack; or, the bottom weight 132 is threadedly connected to the lower end of the rod body 131, and other weights 132 are stacked above the bottom weight 132, and the upper weight 132 is plugged into the rod body 131 in the radial direction, so that the upper weight 132 is more convenient to take and put.

[0075] Furthermore, a notch 1311 is provided on the outer peripheral surface of the rod body 131, and the rod body 131 also includes a mounting portion 1312, which is located below the notch 1311. The weight 132 has an insertion hole 1321 and an insertion groove 1322, one end of the insertion groove 1322 is connected to the insertion hole 1321, and the other end passes through the outer peripheral surface of the weight 132, the width of the rod body 131 at the notch 1311 is H1, the width of the rod body 131 at the mounting portion 1312 is H2, the width of the insertion groove 1322 is H3, the width of the insertion hole 1321 is H4, and H1≤H3≤H2≤H4. The bottom layer of weights 132 is installed at the lower end of the rod body 131 by means of a threaded connection. When installing the upper layer of weights 132, the notch 1311 of the rod body 131 is inserted into the plug-in hole 1321 through the plug-in slot 1322 of the weight 132, and then the weight 132 slides downward until the mounting portion 1312 is passed through the plug-in hole 1321, and then placed above the lower layer of weights 132 to complete the installation of the upper layer of weights 132; in addition, since the width of the mounting portion 1312 is greater than the width of the plug-in slot 1322, the mounting portion 1312 can be constrained in the plug-in hole 1321 to prevent the upper layer of weights 132 from detaching from the rod body 131.

[0076] The cold hammer 130 also includes a handle 134, which is connected to the top of the rod body 131. The handle 134 can be held by the operator's hand. The operator can lift the cold hammer 130 or lower the cold hammer 130 through the handle 134, which makes it more convenient to operate the cold hammer 130. Furthermore, part of the handle 134 is provided to protrude relative to the outer peripheral surface of the rod body 131 to increase the controllable area of ​​the handle 134, which is convenient for the operator to hold; the handle 134 can be made of plastic material to reduce the discomfort of the operator when operating the handle 134 in a low temperature environment.

[0077] Reference Figure 6The utility model also provides a cold hammer mechanism 100 of another embodiment, the cold hammer mechanism 100 includes a cold stage 110, a driving module 120 and a cold hammer 130. Different from the above embodiment, the driving module 120 includes a first slide rail 127, two second slide rails 128 arranged side by side and a sliding body 129. The two second slide rails 128 are arranged on opposite sides of the cold stage 110. The extension directions of the first slide rail 127 and the second slide rail 128 intersect. The two ends of the first slide rail 127 are respectively slidably connected to the two second slide rails 128. The sliding body 129 is slidably connected to the first slide rail 127. The cold hammer 130 is vertically slidably connected to the sliding body 129. Therefore, while the sliding body 129 slides along the first slide rail 127, it can follow the first slide rail 127 and move synchronously along the second slide rail 128, so that the cold hammer 130 can move in two directions at the same time. The range of motion of the cold hammer 130 is large, and the samples located at different positions of the cold stage 110 can be frozen.

[0078] It can be understood that when the projection of the cold stage 110 in the horizontal plane is a rectangle, two second slide rails 128 can be set parallel to the long side of the cold stage 110, and the first slide rail 127 is located directly above the cold stage 110 and parallel to the short side of the cold stage 110, and the extension direction of the first slide rail 127 is perpendicular to that of the second slide rail 128.

[0079] Reference Figure 3 The utility model also provides a freezing microtome, including the above-mentioned cold hammer mechanism 100, and also includes a slicing mechanism, and the slicing mechanism is used to slice the frozen sample.

[0080] The freezing microtome comprises a housing 200 , wherein the cold hammer mechanism 100 and the slicing mechanism are both arranged inside the housing 200 , wherein the guide rail 121 and the second slide rail 128 can be installed on the inner wall of the housing 200 .

[0081] The embodiments of the utility model are described in detail above in conjunction with the accompanying drawings, but the utility model is not limited to the above embodiments. Various changes can be made within the knowledge of ordinary technicians in the relevant technical field without departing from the purpose of the utility model. In addition, the embodiments of the utility model and the features in the embodiments can be combined with each other without conflict.

Claims

1. Cold hammer mechanism, characterized in that: include: A cold stage for placing samples to be frozen; A driving module is located above the cold stage, and comprises a guide rail, a moving body and a swing arm, wherein the guide rail is arranged along the circumference of the cold stage, the moving body is slidably connected to the guide rail, and one end of the swing arm is rotatably connected to the moving body; The cold hammer is located above the cold platform and is vertically slidably connected to an end of the swing arm away from the moving body.

2. The cold hammer mechanism according to claim 1, characterized in that: The guide rail is annular and is arranged around the outer periphery of the cooling platform; Alternatively, the guide rails are distributed on one side of the cold stage.

3. The cold hammer mechanism according to claim 1, characterized in that: The cold stage has a first side and a second side opposite to each other in a first direction, the guide rail is arranged on the first side, the cold stage is provided with a plurality of cold zones, each of the cold zones can be used to place a sample to be frozen, the cold zone closest to the second side is defined as an edge cold zone, the farthest position of the cold hammer relative to the first side is the farthest end, and the farthest end is located on a side of the edge cold zone facing away from the first side; and / or, The cold zone closest to the first side is defined as the critical cold zone, the closest position of the cold hammer relative to the first side is defined as the closest end, and the closest end is located on the side of the critical cold zone facing away from the second side.

4. The cold hammer mechanism according to claim 3, characterized in that: The rotation angle of the swing arm is not less than 180°.

5. The cold hammer mechanism according to claim 1, characterized in that: The cold hammer comprises a rod body and a weight, wherein the rod body is connected to one end of the swing arm, and the weight is detachably connected to the lower end of the rod body, and the bottom surface of the weight is used to contact with the sample; Alternatively, the cold hammer includes a rod body and a plurality of weights, wherein the rod body is slidably connected to one end of the swing arm, the plurality of weights are stacked and detachably connected to the lower end of the rod body, and the bottom surface of the bottom layer of the weights is used to contact the sample.

6. The cold hammer mechanism according to claim 5, characterized in that: The cold hammer also includes a handle connected to the top of the rod body.

7. The cold hammer mechanism according to claim 1, characterized in that: The cold hammer comprises a rod body, the swing arm is provided with a mounting hole which penetrates vertically, and the mounting hole has an opening which penetrates to the side of the swing arm, and the opening is used for the rod body to pass through and be installed in the mounting hole.

8. The cold hammer mechanism according to claim 7, characterized in that: The cold hammer also includes a guide sleeve, the rod body is vertically slidably connected in the guide sleeve, the guide sleeve is vertically inserted in the mounting hole and can block the opening.

9. Cold hammer mechanism, characterized in that: include: A cold stage for placing samples to be frozen; A driving module is located above the cold platform, the driving module comprises a first slide rail, two second slide rails arranged side by side and a sliding body, the two second slide rails are arranged on opposite sides of the cold platform, the extension directions of the first slide rail and the second slide rail intersect, the two ends of the first slide rail are respectively slidably connected to the two second slide rails, and the sliding body is slidably connected to the first slide rail; The cold hammer is located above the cold stage and is vertically slidably connected to the sliding body.

10. A cryostat, characterized in that include: The cold hammer mechanism according to any one of claims 1 to 9; The slicing mechanism is used to slice the frozen samples.

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