Electrochemical luminescence auxiliary detection device

Abstract

The electrochemical luminescence auxiliary detection device comprises a conductive interface assembly, an upper cover and a bottom shell, the conductive interface assembly comprises an interface base, the right end of the interface base extends to form a conductive insertion piece part, and the left end of the interface base is provided with a conductive insertion groove part used for allowing an electrochemical screen printing electrode strip to be inserted in. The right end of the upper cover is rotatably mounted at the upper part of the left end of the interface seat; the right end of the bottom shell is rotatably mounted at the lower part of the left end of the interface seat; the bottom shell is provided with an immersion liquid groove for accommodating an electrochemical screen printing electrode strip, and a transparent window is arranged at the position, corresponding to the immersion liquid groove, of the upper cover; and the locking piece is used for locking the upper cover and the bottom shell in a closed state. According to the utility model, the assembly structure is reasonable, and the interface seat, the upper cover and the bottom shell are matched, so that the electrochemical screen printing electrode strip can be completely sealed, and the interference of the external environment on the accuracy of a detection result is avoided or reduced; the electrochemical screen printing electrode strip is convenient to replace, and the detection cost can be relatively reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of electrochemical luminescence detection, in particular to an electrochemical luminescence auxiliary detection device. Background Art

[0002] Electrochemiluminescence (ECL) is the product of the combination of chemiluminescence and electrochemical methods. It is a redox-induced light emission phenomenon with the characteristics of electrochemical controllability, high sensitivity, high selectivity, wide linear range, and low background. In particular, based on Ru(bpy)3 2+ The ECL phenomenon has excellent efficiency and stability and has received extensive attention and application in the fields of bioanalysis, medicine, pharmacy and clinical practice.

[0003] Electrochemical screen-printed electrode strips are usually used for electrochemiluminescence detection. The labeled probes are fixed on the loaded Ru(bpy)3 2+ The surface of the electrochemical screen-printed electrode strip is used to construct an ECL biosensor to detect the target object to be detected. By adjusting the ECL signal intensity on the electrode surface, the trace analysis of the target object to be detected is realized. When performing the detection, some of them first dip the electrochemical screen-printed electrode strip into the sample to be tested, and then insert the conductive end of the electrochemical screen-printed electrode strip into the conductive socket of the electrochemical luminescence detection device, and give an electrical signal to the electrochemical screen-printed electrode strip through the electrochemical luminescence detection device to perform an electrochemical luminescence reaction, and detect the luminescence signal intensity through the luminescence detection unit in the electrochemical luminescence detection device, thereby completing the detection of the sample to be tested; some of them use dry electrochemical luminescence chips (such as: a dry three-electrode electrochemical luminescence chip with an authorization announcement number of CN217931512U, a dry immune closed bipolar electrochemical luminescence chip with an authorization announcement number of CN217587030U) to detect the sample to be tested.

[0004] However, during the above detection process, the electrode reaction area is usually directly exposed to the external environment, which may cause contamination to the target object to be detected and affect the accuracy of the detection result. In addition, in some cases, it is often necessary to add reaction liquid to the electrode reaction area multiple times. Obviously, the operation of repeatedly plugging and unplugging and sticking reaction liquid using electrochemical screen-printed electrode strips is not convenient enough. Although the electrochemical luminescence chip is convenient for subsequent multiple sample additions, its electrode part is usually not easy to replace and is discarded as a whole after use, and the detection cost is relatively high. Utility Model Content

[0005] The purpose of the utility model is to provide an electrochemical luminescence auxiliary detection device to solve the problems raised in the above background technology.

[0006] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0007] An electrochemical luminescence auxiliary detection device includes a conductive interface component, an upper cover and a bottom shell. The conductive interface component includes an interface seat, a conductive plug portion extends from the right end of the interface seat, and a conductive slot portion for inserting an electrochemical screen-printed electrode strip is provided at the left end of the interface seat. The right end of the upper cover is rotatably mounted on the upper left end of the interface seat, and the right end of the bottom shell is rotatably mounted on the lower left end of the interface seat; the bottom shell has an immersion tank for accommodating the electrochemical screen-printed electrode strip, and a transparent window is provided on the upper cover corresponding to the immersion tank; and also includes a locking member for locking the upper cover and the bottom shell in a closed state.

[0008] Preferably, the locking member is specifically a locking end cover. When the upper cover and the bottom shell are closed, the locking end cover is simultaneously mounted on the left ends of the upper cover and the bottom shell to lock the upper cover and the bottom shell in a closed state. The locking end cover has a simple structural design and can be mounted on the left ends of the upper cover and the bottom shell to achieve closed locking between the upper cover and the bottom shell.

[0009] Preferably, the left end outer walls of the upper cover and the bottom shell are both provided with a step groove, and the locking end cover is fitted on the step groove.

[0010] Preferably, a pressing plate for pressing the middle portion of the electrochemical screen-printed electrode strip into the immersion tank is also extended inside the upper cover.

[0011] Preferably, at least one set of presser feet for pressing the free end of the electrochemical screen-printed electrode strip into the immersion tank is extended inside the upper cover. By properly arranging the presser plate and the presser feet, it is effectively prevented that the free end of the electrochemical screen-printed electrode strip is warped and cannot contact the reaction liquid added into the immersion tank.

[0012] Preferably, a sample adding port is provided on the upper surface of the left end of the upper cover, and a movable plug is slidably installed at the sample adding port for blocking or opening the sample adding port. By pushing the movable plug to open the sample adding port, it is convenient to add the reaction liquid into the immersion tank multiple times.

[0013] Preferably, the moving direction of the movable plug plate is the same as the length extension direction of the upper cover, and the locking end cover is provided with a guide groove for the movable plug plate to move.

[0014] Preferably, it also includes a sleeve for sleeved on the right end of the interface seat, the sleeve is used to cover the conductive plug part and protect the conductive plug part from dust.

[0015] Compared with the prior art, the beneficial effects of the utility model are as follows: the utility model reasonably designs the assembly structure of the conductive interface component, the upper cover and the bottom shell, and through the cooperation of the interface seat, the upper cover and the bottom shell, the electrochemical screen-printed electrode strip can be completely enclosed, thereby avoiding or reducing the interference of the external environment on the accuracy of the detection result; the upper cover and the bottom shell can be rotated and opened relative to the interface seat, which is convenient for the insertion and removal of the electrochemical screen-printed electrode strip, and the replacement of the electrochemical screen-printed electrode strip is convenient, which can relatively reduce the detection cost; through the reasonable design of the sample addition port and the movable plug-in plate, it is convenient to add the reaction liquid to the immersion tank multiple times during the detection process, and there is no need to repeatedly insert and remove the electrochemical screen-printed electrode strip, and the operation is relatively convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the three-dimensional structure of an electrochemiluminescence auxiliary detection device;

[0017] Figure 2 It is a schematic diagram of the internal cross-sectional structure of an electrochemiluminescence auxiliary detection device;

[0018] Figure 3 A schematic diagram of the internal cross-sectional structure of an electrochemiluminescence auxiliary detection device when adding a sample;

[0019] Figure 4 This is a schematic diagram of the three-dimensional structure of an electrochemiluminescence auxiliary detection device when it is unfolded.

[0020] In the figure: 100-electrochemical screen-printed electrode strip, 1-conductive interface assembly, 11-interface seat, 12-rotating ear plate, 13-pin shaft, 14-conductive plug portion, 15-plug section conductive sheet, 16-connecting section conductive sheet, 17-elastic bending section conductive sheet, 18-conductive slot portion, 2-upper cover, 21-transparent window, 22-pressing plate, 23-pressing foot, 3-bottom shell, 31-immersion tank, 4-locking end cover, 41-guide groove, 5-sleeve, 6-movable plug plate, 61-convex strip portion. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0022] See also Figures 1 to 4The utility model provides a technical solution: an electrochemical luminescence auxiliary detection device, including a conductive interface component 1, an upper cover 2 and a bottom shell 3, the conductive interface component 1 includes an interface seat 11, a conductive plug portion 14 extends from the right end of the interface seat 11, and a conductive slot portion 18 for inserting an electrochemical screen-printed electrode strip 100 is provided at the left end of the interface seat 11. In order to make the conductive end of the electrochemical screen-printed electrode strip 100 conductive with the conductive socket of the electrochemical luminescence detection device in the prior art, a conductive strip is also provided in the interface seat 11, and the conductive strip includes an integrally connected plug-in section conductive sheet 15, a connecting section conductive sheet 16 and an elastic bending section conductive sheet 17. The plug-in section conductive sheet 15 is fixedly arranged on the surface of the conductive plug portion 14 for contacting the conductive socket of the electrochemical luminescence detection device, and the connecting section conductive sheet 16 is embedded in the interface seat 11 for use. The conductive sheet 15 of the conductive plug section is connected with the conductive sheet 17 of the elastic bending section, and the conductive sheet 17 of the elastic bending section is distributed inside the conductive slot portion 18 for contacting the conductive end of the electrochemical screen-printed electrode strip 100. In the present embodiment, in order to facilitate the conductive end of the electrochemical screen-printed electrode strip 100 to be inserted into the conductive slot portion 18, the right end of the upper cover 2 is rotatably mounted on the upper left end of the interface seat 11, and the right end of the bottom shell 3 is rotatably mounted on the lower left end of the interface seat 11; the bottom shell 3 has an immersion tank 31 for accommodating the electrochemical screen-printed electrode strip 100, and a transparent window 21 is arranged on the upper cover 2 corresponding to the immersion tank 31. The luminescent signal in the electrochemical treatment process can be detected by the luminescent detection unit in the electrochemical luminescence detection device through the transparent window 21; the present embodiment also includes a locking member for locking the upper cover 2 and the bottom shell 3 in a closed state.

[0023] The working principle of the utility model is: the utility model reasonably designs the assembly structure of the conductive interface component 1, the upper cover 2 and the bottom shell 3, and through the cooperation of the interface seat 11, the upper cover 2 and the bottom shell 3, the electrochemical screen-printed electrode strip 100 can be completely enclosed, thereby avoiding or reducing the interference of the external environment on the accuracy of the detection result; in addition, the upper cover 2 and the bottom shell 3 can be rotated and opened relative to the interface seat 11, so as to facilitate the insertion and removal of the electrochemical screen-printed electrode strip 100, and it is convenient to replace the electrochemical screen-printed electrode strip 100, which can relatively reduce the detection cost.

[0024] In order to facilitate the cleaning of the upper cover 2 and the bottom shell 3, a rotating ear plate 12 is extended from the upper and lower parts of the left end of the interface seat 11, and the rotating ear plate 12 is installed with a pin shaft 13 through threaded cooperation. The right ends of the upper cover 2 and the bottom shell 3 are respectively rotated and cooperated on the corresponding pin shaft 13. When cleaning and disassembly are required, the pin shaft 13 is unscrewed from the rotating ear plate 12, and the upper cover 2 and the bottom shell 3 can be removed, which is easy to operate.

[0025] As a further specific solution, the locking member is specifically a locking end cover 4. When the upper cover 2 and the bottom shell 3 are closed, the locking end cover 4 is simultaneously mounted on the left ends of the upper cover 2 and the bottom shell 3 to lock the upper cover 2 and the bottom shell 3 in a closed state. The locking end cover 4 has a simple structural design and can be mounted on the left ends of the upper cover 2 and the bottom shell 3 to achieve closed locking between the upper cover 2 and the bottom shell 3, which is easy to operate and use.

[0026] For the overall beauty of the structure and the fitting of the locking end cover 4 , the left end outer walls of the upper cover 2 and the bottom shell 3 are both provided with a step groove 24 , and the locking end cover 4 fits in the step groove 24 .

[0027] As a specific solution, a pressing plate 22 for pressing the middle of the electrochemical screen-printed electrode strip 100 into the immersion tank 31 is further extended inside the upper cover 2. In order to prevent the free end of the electrochemical screen-printed electrode strip 100 from warping up and being unable to contact the added reaction solution, at least one set of pressing feet 23 for pressing the free end of the electrochemical screen-printed electrode strip 100 into the immersion tank 31 is further extended inside the upper cover 2.

[0028] As a specific solution, a sample adding port is also provided on the upper surface of the left end of the upper cover 2, and a movable plug plate 6 for blocking or opening the sample adding port is slidably installed at the sample adding port. In order to facilitate the pushing of the movable plug plate 6, a convex strip 61 is extended from the movable plug plate 6. Figure 3 As shown, when the reaction liquid needs to be added, the movable plug plate 6 can be pushed to open the sample adding port, so as to add the reaction liquid into the immersion tank 31 multiple times. There is no need to repeatedly plug and unplug the electrochemical screen-printed electrode strip 100, and the operation is relatively convenient.

[0029] In this embodiment, the moving direction of the movable plug plate 6 is the same as the length extension direction of the upper cover 2. In order to prevent the locking end cover 4 from affecting the flexible movement of the movable plug plate 6, a guide groove 41 for the movement of the movable plug plate 6 is provided on the locking end cover 4. Of course, as another solution, the moving direction of the movable plug plate 6 can also be perpendicular to the length extension direction of the upper cover 2. In this case, there is no need to provide a corresponding guide groove 41 on the locking end cover 4.

[0030] As a further specific solution, in order to prevent dust from adhering to the conductive plug portion 14 when the device is not in use, the present embodiment further includes a sleeve 5 for being sleeved on the right end of the interface seat 11, and the sleeve 5 is used to cover the conductive plug portion 14 to protect the conductive plug portion 14 and avoid affecting subsequent contact conduction.

[0031] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. An electrochemiluminescence auxiliary detection device, characterized in that: The conductive interface assembly (1) comprises an interface seat (11), an upper cover (2) and a bottom shell (3), wherein the conductive interface assembly (1) comprises an interface seat (11), a conductive insert portion (14) extending from the right end of the interface seat (11), a conductive slot portion (18) for inserting an electrochemical screen-printed electrode strip (100) is arranged at the left end of the interface seat (11), the right end of the upper cover (2) is rotatably mounted on the upper left end of the interface seat (11), and the right end of the bottom shell (3) is rotatably mounted on the lower left end of the interface seat (11); The bottom shell (3) has an immersion tank (31) for accommodating the electrochemical screen-printed electrode strip (100), and the upper cover (2) is provided with a transparent window (21) at a position corresponding to the immersion tank (31); It also includes a locking member for locking the upper cover (2) and the bottom shell (3) in a closed state.

2. An electrochemiluminescence auxiliary detection device according to claim 1, characterized in that: The locking member is specifically a locking end cover (4). When the upper cover (2) and the bottom shell (3) are closed, the locking end cover (4) is simultaneously sleeved on the left ends of the upper cover (2) and the bottom shell (3), thereby locking the upper cover (2) and the bottom shell (3) in a closed state.

3. An electrochemiluminescence auxiliary detection device according to claim 2, characterized in that: The left outer side walls of the upper cover (2) and the bottom shell (3) are both provided with a step groove (24), and the locking end cover (4) is fitted on the step groove (24).

4. The electrochemiluminescence auxiliary detection device according to claim 1, characterized in that: A pressing plate (22) is also provided extending inside the upper cover (2) for pressing the middle portion of the electrochemical screen-printed electrode strip (100) into the immersion tank (31).

5. An electrochemiluminescence auxiliary detection device according to claim 4, characterized in that: At least one set of pressing feet (23) for pressing the free ends of the electrochemical screen-printed electrode strips (100) into the immersion tank (31) is also extended inside the upper cover (2).

6. The electrochemiluminescence auxiliary detection device according to claim 3, characterized in that: The upper surface of the left end of the upper cover (2) is also provided with a sample adding port, and a movable plug plate (6) is slidably installed at the sample adding port for blocking or opening the sample adding port.

7. An electrochemiluminescence auxiliary detection device according to claim 6, characterized in that: The moving direction of the movable plug plate (6) is the same as the length extension direction of the upper cover (2), and the locking end cover (4) is provided with a guide groove (41) for the movable plug plate (6) to move.

8. An electrochemiluminescence auxiliary detection device according to any one of claims 1 to 7, characterized in that: It also comprises a sleeve (5) for being sleeved on the right end of the interface seat (11), and the sleeve (5) is used for covering the conductive inserting piece (14).

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