A liquid chromatography column oven

By designing a liquid chromatographic column column thermostat including bearings, rotating shafts, screws, movable plates and clamps, and combining mini-hot air fans, hollow plates and U-shaped electric heating pipes, the problems of poor applicability and uneven heating of existing column thermostats are solved, and uniform fixation and uniform heating of columns of different sizes are achieved, which improves detection accuracy.

CN222704559UActive Publication Date: 2025-04-01汕头市检验检测中心
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Patent Information

Application Number
CN202420988815.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-09
Publication Date
2025-04-01
Estimated Expiration
2034-05-09

AI Technical Summary

Technical Problem

The existing column thermostat has poor applicability and cannot adapt to liquid chromatographic columns of different sizes. The heating is uneven, which affects the detection accuracy.

Method used

A liquid chromatographic column column thermostat was designed, using a combined structure of bearings, rotating shafts, screws, movable plates and clamping plates to achieve clamping and fixing columns of different sizes; at the same time, a mini-hot air fan, hollow plates and U-shaped electric heating tubes were used to achieve uniform spraying of hot air and uniform heating of liquid chromatographic columns.

Benefits of technology

It improves the applicability of the column thermostat, achieves uniform fixation and uniform heating of liquid chromatographic columns of different sizes, and improves detection accuracy.

✦ Generated by Eureka AI based on patent content.

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    Figure CN222704559U_ABST
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Abstract

The utility model discloses a liquid chromatography column temperature box, belonging to the technical field of column temperature boxes, which includes a base, the top of the base is fixedly connected to a box body, the front side of the box body is movably connected to a box door through a hinge, a mini hot air blower is penetrated on one side of the box body, a hollow plate is fixedly connected to the box body, the air outlet end of the mini hot air blower is located below the hollow plate, and the top of the hollow plate and the top of the inner wall of the box body are fixedly connected with bearings. Through the joint action of bearings, rotating shafts, screws, movable plates and clamps, the box body can clamp and fix liquid chromatography columns of different sizes, thereby improving the applicability of the box body. Through the joint action of the mini hot air blower, the hollow plate and the U-shaped electric heating tube, the hot air entering the box body is uniformly sprayed upwards and uniformly contacts the outer surface of the liquid chromatography column, and the U-shaped electric heating tube heats the outside of the liquid chromatography column to achieve a uniform heating effect.
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Description

Technical Field

[0001] The utility model relates to the technical field of column temperature boxes, and more specifically, to a liquid chromatography column temperature box. Background Art

[0002] Liquid chromatography is widely used in the fields of pharmaceutical research and development and product testing. The demand for liquid chromatography columns in the laboratories of various research and development companies and production companies is increasing. From the early method development, screening of different quality standards, method optimization, mid-term and late durability inspections and stability inspections under different conditions, there is a huge demand for chromatography columns. The column oven is a standard configuration of liquid chromatography and is widely used in liquid phase systems. The column oven plays an important role in maintaining the temperature of the chromatography column, reducing the pressure of the chromatography system, and improving the column efficiency.

[0003] Most of the current column ovens can only fix liquid chromatography columns of specific sizes. However, during use, the size of the liquid chromatography column is not necessarily the same as the size of the column oven, resulting in poor applicability of the column oven. At the same time, its heating structure is mostly designed on one side of its inner wall, resulting in uneven heating of the liquid chromatography column, affecting the detection accuracy of the liquid chromatography column. Utility Model Content

[0004] (1) Technical issues to be solved

[0005] In view of the shortcomings of the prior art, the utility model aims to provide a liquid chromatography column oven, which has the characteristics of high applicability and uniform heating.

[0006] (2) Technical solution

[0007] To achieve the above-mentioned purpose, the utility model provides a liquid chromatography column temperature box, comprising a base, the top of the base is fixedly connected to a box body, the front side of the box body is movably connected to a box door through a hinge, a mini hot air blower is passed through one side of the box body, a hollow plate is fixedly connected to the box body, the air outlet end of the mini hot air blower is located below the hollow plate, the top of the hollow plate and the top of the inner wall of the box body are fixedly connected to bearings, two bearings are movably provided with rotating shafts, the opposite ends of the two rotating shafts are fixedly connected with the same screw, one end of one rotating shaft passes through the box body and is fixedly connected with a shift block, the screw is threadedly connected with a movable plate, two telescopic rods are passed through the hollow plate, one end of the two telescopic rods are respectively fixedly connected to the bottom two sides of the movable plate, a splint is fixedly connected to one side of the movable plate, and a U-shaped electric heating tube is fixedly connected to the box body.

[0008] When a liquid chromatography column temperature box of the present technical solution is used, the box can clamp and fix liquid chromatography columns of different sizes through the joint action of the bearings, rotating shafts, screws, movable plates and clamps, thereby improving the applicability of the box. Through the joint action of the mini hot air blower, the hollow plate and the U-shaped electric heating tube, the hot air entering the box is evenly ejected upward and evenly contacts the outer surface of the liquid chromatography column, and the U-shaped electric heating tube heats the outside of the liquid chromatography column to achieve a uniform heating effect.

[0009] Furthermore, four corners of the bottom of the base are fixedly connected with suction cups, and a controller is arranged on one side of the top of the base.

[0010] Furthermore, a handle is fixedly connected to the box door, and a handle is fixedly connected to the top of the box body.

[0011] Furthermore, a positioning line is provided on the top of the hollow plate, and an anti-slip pad is fixedly connected to the bottom of the clamping plate.

[0012] Furthermore, a temperature sensor is fixedly connected to the top of the clamping plate.

[0013] (3) Beneficial effects

[0014] In summary, the utility model has the following beneficial effects:

[0015] 1. Through the joint action of bearings, rotating shafts, screws, movable plates and clamps, the box can clamp and fix liquid chromatography columns of different sizes, thereby improving the applicability of the box. Through the joint action of the mini hot air blower, hollow plate and U-shaped electric heating tube, the hot air entering the box is evenly ejected upward and evenly contacts the outer surface of the liquid chromatography column. The U-shaped electric heating tube heats the outside of the liquid chromatography column to achieve a uniform heating effect.

[0016] 2. By setting the suction cup, it is convenient to fix the position of the box. By setting the anti-slip pad, the clamping effect of the liquid chromatography column is improved. By setting the temperature sensor, the temperature inside the box can be detected. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the specific implementation of the utility model or the technical solution in the prior art, the drawings required for describing the specific implementation or the prior art will be briefly introduced below. Obviously, the drawings described below are only one implementation of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 This is a schematic diagram of the front view structure of the utility model;

[0019] Figure 2 for Figure 1 Schematic diagram of the cross-section structure of the middle box.

[0020] The symbols in the accompanying drawings are:

[0021] 1. Base; 2. Suction cup; 3. Controller; 4. Box body; 5. Box door; 6. Handle; 7. Carrying handle; 8. Mini hot air blower; 9. Temperature sensor; 10. Hollow plate; 11. Positioning line; 12. Bearing; 13. Rotating shaft; 14. Screw; 15. Movable plate; 16. Dial block; 17. Clamp; 18. Anti-slip pad; 19. Telescopic rod; 20. U-shaped electric heating tube. DETAILED DESCRIPTION

[0022] In order to make the technical means, creative features, objectives and effects achieved by the utility model easy to understand, the technical scheme in the specific implementation mode of the utility model is clearly and completely described below to further illustrate the utility model. Obviously, the specific implementation mode described is only a part of the implementation mode of the utility model, rather than all styles.

[0023] Example:

[0024] The following is combined with Figure 1-2 The utility model is described in further detail.

[0025] See also Figure 1-2 The utility model provides a technical solution: a liquid chromatography column temperature box, comprising a base 1, a box body 4 is fixedly connected to the top of the base 1, a box door 5 is movably connected to the front side of the box body 4 through a hinge, a mini hot air blower 8 is penetrated on one side of the box body 4, a hollow plate 10 is fixedly connected in the box body 4, an air outlet end of the mini hot air blower 8 is located below the hollow plate 10, a bearing 12 is fixedly connected to the top of the hollow plate 10 and the top of the inner wall of the box body 4, a rotating shaft 13 is movably penetrated in the two bearings 12, the opposite ends of the two rotating shafts 13 are fixedly connected with the same screw 14, one end of one rotating shaft 13 passes through the box body 4 and is fixedly connected with a shift block 16, a movable plate 15 is threadedly connected on the screw 14, through the bearing 12, The combined effect of the rotating shaft 13, the screw 14, the movable plate 15 and the splint 17 enables the box 4 to clamp and fix liquid chromatography columns of different sizes, thereby improving the applicability of the box 4. Two telescopic rods 19 are passed through the hollow plate 10, and one end of the two telescopic rods 19 is respectively fixedly connected to the two sides of the bottom of the movable plate 15, and one side of the movable plate 15 is fixedly connected to the splint 17. A U-shaped electric heating tube 20 is fixedly connected to the box 4. Through the combined effect of the mini hot air blower 8, the hollow plate 10 and the U-shaped electric heating tube 20, the hot air entering the box 4 is evenly ejected upward and evenly contacts the outer surface of the liquid chromatography column, and the U-shaped electric heating tube 20 heats the outside of the liquid chromatography column to achieve a uniform heating effect.

[0026] Specifically, suction cups 2 are fixedly connected to the four bottom corners of the base 1, a controller 3 is provided on the top side of the base 1, a handle 6 is fixedly connected to the box door 5, a handle 7 is fixedly connected to the top of the box body 4, a positioning line 11 is provided on the top of the hollow plate 10, an anti-slip pad 18 is fixedly connected to the bottom of the splint 17, and a temperature sensor 9 is fixedly connected to the top of the splint 17.

[0027] By adopting the above technical solution, by setting the suction cup 2, it is convenient to fix the position of the box 4. The controller 3 can be a conventional known device for control such as a computer. The controller 3 is electrically connected to the mini hot air blower 8, the temperature sensor 9 and the U-shaped electric heating tube 20 through wires. By setting the anti-slip pad 18, the clamping effect of the liquid chromatography column is improved. By setting the temperature sensor 9, the temperature inside the box 4 can be detected.

[0028] The working principle of the utility model is as follows: when in use, the base 1 is placed on the desktop, the box body 4 is pressed to make the suction cup 2 adsorb on the desktop, the position of the box body 4 is fixed, the box body 4 is connected to the external power supply, the box door 5 is unfolded, the liquid chromatography column is placed on the hollow plate 10 so that it is located within the positioning line 11, the shift block 16 is rotated, and the shift block 16 drives the screw 14 to rotate via the rotating shaft 13, so that the movable plate 15 falls along the screw 14, and the anti-skid pad 18 under the clamping plate 17 is pressed against the top of the liquid chromatography column to clamp it, and the box door 5 is closed. The mini hot air blower 8 works to introduce hot air into the box body 4, and the hot air evenly passes through the hollow plate 10 and contacts the liquid chromatography column. At the same time, the U-shaped electric heating tube 20 works to increase the temperature in the box body 4, so as to achieve uniform heating of the liquid chromatography column. The temperature sensor 9 detects the temperature in the box body 4, and the detection result is fed back to the controller 3 for display.

[0029] This specific embodiment is merely an explanation of the present invention and is not a limitation of the present invention. After reading this specification, those skilled in the art may make non-creative modifications to the present embodiment as needed, but such modifications are protected by patent law as long as they are within the scope of the claims of the present invention.

Claims

1. A liquid chromatography column oven, comprising a base (1), characterized in that: The top of the base (1) is fixedly connected to a box body (4), a front side of the box body (4) is movably connected to a box door (5) via a hinge, a mini hot air blower (8) is inserted into one side of the box body (4), a hollow plate (10) is fixedly connected inside the box body (4), an air outlet end of the mini hot air blower (8) is located below the hollow plate (10), the top of the hollow plate (10) and the top of the inner wall of the box body (4) are both fixedly connected to bearings (12), two rotating shafts (13) are movably inserted into the two bearings (12), and the two rotating shafts (13) are movable. The opposite ends of the shaft (13) are fixedly connected to the same screw rod (14); one end of the rotating shaft (13) passes through the box body (4) and is fixedly connected to a shift block (16); a movable plate (15) is threadedly connected to the screw rod (14); two telescopic rods (19) are passed through the hollow plate (10); one end of the two telescopic rods (19) are respectively fixedly connected to the two sides of the bottom of the movable plate (15); one side of the movable plate (15) is fixedly connected to a clamping plate (17); and a U-shaped electric heating tube (20) is fixedly connected inside the box body (4).

2. A liquid chromatography column oven according to claim 1, characterized in that: Suction cups (2) are fixedly connected to the four corners of the bottom of the base (1), and a controller (3) is arranged on one side of the top of the base (1).

3. A liquid chromatography column oven according to claim 1, characterized in that: A handle (6) is fixedly connected to the box door (5), and a handle (7) is fixedly connected to the top of the box body (4).

4. A liquid chromatography column oven according to claim 1, characterized in that: A positioning line (11) is provided on the top of the hollow plate (10), and an anti-slip pad (18) is fixedly connected to the bottom of the clamping plate (17).

5. The liquid chromatography column oven according to claim 1, characterized in that: A temperature sensor (9) is fixedly connected to the top of the clamping plate (17).