A fully automatic unfolding instrument

Abstract

The utility model discloses a full-automatic developing instrument, comprising an instrument case, on which a quantitative preparation device is arranged, the quantitative preparation device is connected to a mixing cylinder arranged in the instrument case, and the instrument case is also provided with a layered static cylinder, a thin layer plate assembly, a developing agent storage cylinder body and a developing cylinder, wherein the layered static cylinder and the mixing cylinder are connected via a connecting device; the developing agent storage cylinder body comprises a first storage cylinder and a second storage cylinder; the thin layer plate assembly comprises a thin layer plate body, a moving mechanism and a placement slot, and the placement slot is connected to the developing cylinder via a channel; the full-automatic developing instrument, through the arrangement of the quantitative preparation device, does not require an experimenter to manually prepare the developing agent, realizes automatic proportioning of a solvent, and can quantitatively transfer the solvent into the mixing cylinder, and the arrangement of the layered suction mechanism can also facilitate the layered use of the solvent, thereby improving the safety of the experiment and ensuring the health of the experimenter.

Description

Technical Field

[0001] The utility model belongs to the technical field of full-automatic unfolding instruments, in particular to a full-automatic unfolding instrument. Background Art

[0002] Chromatographic development is a critical step in thin layer chromatography. The use of existing fully automatic developing instruments requires experimenters to manually prepare the developing agent, which cannot achieve automatic solvent proportioning, cannot quantitatively transfer the solvent into the mixing tank, and cannot automatically take the solvent in layers. This is not only not conducive to the health of experimenters, but also reduces experimental efficiency. Utility Model Content

[0003] The purpose of the utility model is to provide a fully automatic developing instrument to solve the problem that the use of the fully automatic developing instrument in the prior art requires the experimenter to manually prepare the developing agent, cannot achieve automatic solvent proportioning, cannot quantitatively transfer the solvent into the mixing cylinder, and cannot automatically take the solvent in layers, which is not only not conducive to the health of the experimenter, but also reduces the experimental efficiency.

[0004] Technical solution:

[0005] A fully automatic developing instrument, comprising an instrument case, a quantitative preparation device is arranged on the instrument case, the quantitative preparation device is connected to a mixing cylinder arranged in the instrument case, a stratified static cylinder, a thin layer plate assembly, a developing agent storage cylinder and a developing cylinder are also arranged in the instrument case, and the stratified static cylinder is connected to the mixing cylinder via a connecting device;

[0006] The developing agent storage cylinder body comprises a first storage cylinder and a second storage cylinder, wherein the first storage cylinder and the second storage cylinder are connected to the mixing cylinder via a mixing and conveying mechanism, the first storage cylinder and the second storage cylinder are connected to the layered static cylinder via a layered suction mechanism, and the first storage cylinder and the second storage cylinder are connected to the developing cylinder via a solvent conveying mechanism respectively;

[0007] The thin layer plate assembly comprises a thin layer plate body, a moving mechanism and a placement groove, wherein the moving mechanism is arranged in the placement groove for storing and placing the thin layer plate body, the placement groove is connected to the deployment cylinder through a channel, and the thin layer plate body enters the deployment cylinder through the channel;

[0008] The layered absorption mechanism includes a layered absorption component and a layered identification component. When the quantitative preparation device quantitatively inputs the solvent into the mixing cylinder, the mixing delivery mechanism absorbs and distributes the mixed solvent according to the set volume and inputs it into the first storage cylinder and the second storage cylinder. The developing agent in the first storage cylinder first enters the developing cylinder through the solvent delivery mechanism and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder enters the developing cylinder through the solvent delivery mechanism. The thin layer plate enters the developing cylinder driven by the moving mechanism and performs thin layer development according to the set program. If it is necessary to separate The connecting device first inputs the solvent in the mixing cylinder into the stratified static cylinder for static stratification, and the stratified suction component cooperates with the information identified by the stratified identification component to absorb and distribute the stratified solvent according to the set volume into the first storage cylinder and the second storage cylinder. The developing agent in the first storage cylinder first enters the developing cylinder through the solvent delivery mechanism and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder enters the developing cylinder through the solvent delivery mechanism, and the thin layer plate enters the developing cylinder driven by the moving mechanism to carry out thin layer development according to the set program.

[0009] In a further embodiment, the quantitative preparation device includes a plurality of liquid storage boxes for storing solvents, each of which is connected to the mixing cylinder via a transmission pipeline, and a solenoid valve is provided on the transmission pipeline; the solvent can be prepared and mixed quantitatively and automatically.

[0010] In a further embodiment, the connecting device comprises a solvent transfer pump, the suction end of the solvent transfer pump is connected to the mixing cylinder through a pipeline, and the infusion end of the solvent transfer pump is connected to the stratified static cylinder through a pipeline.

[0011] In a further embodiment, the mixing delivery mechanism comprises a mixing delivery pump, the liquid suction end of the mixing delivery pump is connected to the mixing cylinder via a first liquid extraction pipeline, and the liquid delivery end of the mixing delivery pump is connected to the developing agent storage cylinder via a first T-shaped pipeline;

[0012] The layered suction assembly includes a layered delivery pump, the liquid suction end of the layered delivery pump is connected to the layered static cylinder through a second liquid extraction pipeline, and the liquid delivery end of the layered delivery pump is connected to the developing agent storage cylinder through a second T-shaped pipeline;

[0013] The layer recognition component includes a liquid level recognition sensor.

[0014] In a further embodiment, the second liquid extraction pipeline includes a fixed pipe, a telescopic pipe and a suction pipe which are arranged in sequence, the two ends of the telescopic pipe are respectively connected to the fixed pipe and the suction pipe, the fixed pipe is connected to the stratified delivery pump, and the suction pipe is located in the stratified static cylinder;

[0015] A lifting component is also provided on the stratified static cylinder, and the lifting component drives the suction tube to move in the stratified static cylinder; the position of the suction tube can be adjusted according to the stratified position of the solvent.

[0016] In a further embodiment, the moving mechanism includes an electric clamp and a position adjustment component, the position adjustment component is arranged in the placement groove, the position adjustment component includes an adjusting screw and an adjusting nut threadedly connected to the adjusting screw, and the electric clamp is installed on the adjusting nut to clamp the thin layer plate.

[0017] In a further embodiment, the solvent delivery mechanism includes two groups of solvent delivery components, which input the solvent in the developing agent storage cylinder into the developing cylinder, the liquid delivery ends of the two groups of solvent delivery components are connected to the developing cylinder, and the liquid collection ends of the two groups of solvent delivery components are respectively connected to the first storage cylinder and the second storage cylinder, and the solvent delivery components include a solvent delivery pump.

[0018] The beneficial effects of the utility model are as follows: through the setting of the quantitative preparation device, there is no need for the experimenter to manually prepare the developing agent, the automatic proportioning of the solvent is realized, and the solvent can also be quantitatively transferred into the mixing cylinder. Through the setting of the layered suction mechanism, the solvent can also be conveniently taken in layers, which improves the safety of the experiment, ensures the health of the experimenter, and also improves the efficiency of the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a front sectional structural schematic diagram of the utility model.

[0020] Figure 2 The utility model Figure 1 Enlarged structural diagram at A in the middle.

[0021] Figure 3 It is a schematic diagram of the cross-sectional structure of the second liquid extraction pipeline of the utility model.

[0022] Figure 4 It is a schematic diagram of the top view structure of the instrument box of the utility model.

[0023] The figures are marked as follows: instrument case 1, thin layer plate assembly 11, placement slot 111, thin layer plate body 112, electric clamp 113, position adjustment assembly 114, channel 115, expansion cylinder 12, solvent delivery assembly 13, control panel 14, quantitative preparation device 2, liquid storage box 21, transmission pipeline 22, solenoid valve 23, mixing cylinder 3, stratified static cylinder 4, first storage cylinder 5, second storage cylinder 6, connecting device 7, stratified suction mechanism 8, stratified delivery pump 81, second liquid extraction pipeline 82, suction tube 821, telescopic tube 822, lifting assembly 823, second T-shaped pipeline 83, mixing delivery mechanism 9, mixing delivery pump 91, first liquid extraction pipeline 92, first T-shaped pipeline 93, solenoid valve 10. DETAILED DESCRIPTION

[0024] In the following description, a large number of specific details are given to provide a more thorough understanding of the utility model. However, it is obvious to those skilled in the art that the utility model can be implemented without one or more of these details. In other examples, in order to avoid confusion with the utility model, some technical features known in the art are not described.

[0025] The utility model is further described in detail below in conjunction with the accompanying drawings.

[0026] Reference Figure 1-4, is a fully automatic developing instrument disclosed in the utility model, comprising an instrument box 1, a control panel 14 is provided on the instrument box 1, a quantitative preparation device 2 is provided on the instrument box 1, the quantitative preparation device 2 is connected to a mixing cylinder 3 arranged in the instrument box 1, and a stratified static cylinder 4, a thin layer plate assembly 11, a developing agent storage cylinder body and a developing cylinder 12 are also provided in the instrument box 1, the stratified static cylinder 4 and the mixing cylinder 3 are connected by a connecting device 7; the developing agent storage cylinder body comprises a first storage cylinder 5 and a second storage cylinder 6, the first storage cylinder 5 and the second storage cylinder 6 are connected to the mixing cylinder 3 through a mixing conveying mechanism 9, the first storage cylinder 5 and the second storage cylinder 6 are connected to the developing agent storage cylinder 12 through a stratified suction mechanism 8. The stratified static cylinder 4 is connected, the first storage cylinder 5 and the second storage cylinder 6 are respectively connected to the development cylinder 12 through a solvent delivery mechanism 13, and the solvent can be input into a suitable development cylinder 12 for pre-saturation according to the development requirements, which has good flexibility and practicality. The two storage cylinders are connected by a T-shaped pipe, which can play a role of distinction without affecting the solvent delivery. Solenoid valves 10 are provided on the two T-shaped pipes, which can be switched on and off according to the infusion requirements; the thin layer plate assembly 11 includes a thin layer plate body 112, a moving mechanism and a placement groove 111, the moving mechanism is arranged in the placement groove 111 for storing and placing the thin layer plate body 112, and the placement groove 111 is connected to the development cylinder 1 through a channel 115 2, the thin layer plate body 112 enters the developing cylinder 12 through the channel 115; the layered suction mechanism 8 includes a layered suction component and a layered identification component. When the quantitative preparation device quantitatively inputs the solvent into the mixing cylinder 3, the mixing delivery mechanism 9 absorbs and distributes the mixed solvent according to the set volume and inputs it into the first storage cylinder 5 and the second storage cylinder 6. The developing agent in the first storage cylinder 5 first enters the developing cylinder 12 through the solvent delivery mechanism and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder 6 enters the developing cylinder 12 through the solvent delivery mechanism. The thin layer plate body 112 enters the developing cylinder 12 driven by the moving mechanism. 2. Perform thin layer development according to the set program; if it is necessary to take out the solvent in layers, the connecting device 7 first inputs the solvent in the mixing cylinder 3 into the stratified static cylinder 4 for static stratification, the stratified absorption component cooperates with the information identified by the stratified identification component to absorb the stratified solvent and then absorbs and distributes it into the first storage cylinder 5 and the second storage cylinder 6 according to the set volume, the developing agent in the first storage cylinder 5 first enters the developing cylinder 12 through the solvent delivery mechanism, and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder 6 enters the developing cylinder 12 through the solvent delivery mechanism, and the thin layer plate body 112 enters the developing cylinder 12 driven by the moving mechanism.

[0027] The quantitative preparation device 2 includes a plurality of liquid storage boxes 21 for storing solvents, each of which is connected to the mixing cylinder 3 through a transmission pipeline 22, and a solenoid valve 23 is provided on the transmission pipeline 22. The fully automatic developing instrument also includes an automatic control system, which can set data. When the required solvent channel 115 and the amount are input, the solvent can be automatically transferred to the mixing cylinder 3. For example, the development steps of the thin layer identification of Astragalus medicinal material: the lower layer solution of chloroform-methanol-water (13:7:2) is used as the developing agent, developed, taken out, and dried. Operation: Solvent channel 115A is loaded with chloroform, B is loaded with methanol, and C is loaded with water. Enter "A:B:C is 13:7:2, A is 13ml" on the thin layer chromatography software to realize automatic configuration of the mixed developing agent in the mixing cylinder 3.

[0028] The connecting device 7 includes a solvent transfer pump, the suction end of the solvent transfer pump is connected to the mixing cylinder 3 through a pipeline, and the infusion end of the solvent transfer pump is connected to the stratified static cylinder 4 through a pipeline. When it is necessary to take the solvent in layers, a control instruction such as "take the lower layer solution" or "take the upper layer solution" is input into the control system, and the solvent transfer pump absorbs the solvent in the mixing cylinder 3 and inputs it into the stratified static cylinder 4, and then the stratified absorption mechanism 8 inputs the stratified solvent into the developing agent storage cylinder.

[0029] The mixed delivery mechanism 9 includes a mixed delivery pump 91, the liquid suction end of the mixed delivery pump 91 is connected to the mixing cylinder 3 through a first liquid extraction pipeline 92, and the liquid delivery end of the mixed delivery pump 91 is connected to the developing agent storage cylinder through a first T-shaped pipeline 93; the stratified suction component includes a stratified delivery pump 81, the liquid suction end of the stratified delivery pump 81 is connected to the stratified static cylinder 4 through a second liquid extraction pipeline 82, and the liquid delivery end of the stratified delivery pump 81 is connected to the developing agent storage cylinder through a second T-shaped pipeline 83; the stratified identification component includes a liquid level identification sensor.

[0030] The second liquid extraction pipeline 82 includes a fixed pipe, a telescopic pipe 822 and a suction pipe 821 which are arranged in sequence. The two ends of the telescopic pipe 822 are respectively connected to the fixed pipe and the suction pipe 821. The fixed pipe is connected to the stratified delivery pump 81. The suction pipe 821 is located in the stratified static cylinder 4. The arrangement of the three interconnected and coordinated pipe bodies will not affect the transmission of the solvent. A lifting component 823 is also provided on the stratified static cylinder 4. The lifting component 823 drives the suction pipe 821 to move in the stratified static cylinder 4. The lifting component 823 includes a motor. A power gear is installed at the output end of the motor. The power gear is meshed with a driven gear. The driven gear is coaxially installed on the threaded sleeve. The threaded sleeve is rotatably mounted on the stratified static cylinder 4, the threaded sleeve is sleeved on the outside of the suction tube 821, and the outer surface of the suction tube 821 is provided with an external thread matched with the internal thread of the threaded sleeve. When the stratified solvent far away from the suction tube 821 is sucked, the motor is operated to rotate the threaded sleeve, so that the suction tube 821 is matched with the threaded sleeve to move, so that the suction tube 821 stretches the telescopic tube 822 to approach the solvent to be stratified while moving, and the stratified delivery pump 81 can absorb the stratified solvent prepared by the suction tube 821. The use steps are to measure the liquid level of the first liquid. The specific operation is to add the first liquid to be tested into the stratified static cylinder 4, and the pipe mouth of the second liquid extraction pipeline 82 is placed on the stratified static cylinder 4. The stratified static cylinder 4 is located at the cylinder mouth, the stratified delivery pump 81 is started, and the lifting component 823 drives the suction tube 821 to move downward gradually close to the liquid surface of the first liquid. When the liquid level sensor detects that liquid has entered the suction tube 821, the movement of the suction tube 821 is stopped, and the absolute height of the liquid surface is calculated according to the moving speed and the moving time. In other words, the timing starts when the pipe mouth of the suction tube 821 is located at the cylinder mouth of the stratified static cylinder 4, and the suction tube 821 starts to be moved at the same time, and the timing ends when the liquid level sensor detects that liquid has entered the suction tube 821. This period of time is the moving time, and the moving speed is set manually. The moving time multiplied by the moving speed is the moving distance, and this moving distance is the distance from the cylinder mouth of the stratified static cylinder 4 to the liquid surface of the first liquid. The distance between them is measured, and the second liquid is added to the first liquid. The first liquid and the second liquid are mixed and then stratified again. The liquid level height of the first liquid measured above is used as the reference plane, and the mouth of the suction tube 821 is placed 1-5mm above the reference plane. In theory, the reference plane is the interface between the first liquid and the second liquid. The upper layer of liquid can be sucked by placing the mouth of the suction tube 821 1-2mm above the reference plane. However, for samples that are less likely to be stratified, the interface between the first liquid and the second liquid is more blurred. In this way, the upward distance can be appropriately increased, and the stratification delivery pump 81 is started to rotate forward. The suction tube 821 sucks the liquid solvent into the developing agent storage cylinder. The liquid level sensor is a non-contact pipeline liquid level sensor.

[0031] The moving mechanism includes an electric clamp 113 and a position adjustment component 114. The position adjustment component 114 is arranged in the placement groove 111. The position adjustment component 114 includes an adjusting screw and an adjusting nut threadedly connected to the adjusting screw. The electric clamp 113 is installed on the adjusting nut to clamp the thin layer plate. The adjusting screw is connected to the adjusting motor arranged in the installation groove. When the adjusting motor runs to drive the adjusting screw to rotate forward and reverse, the adjusting nut moves up and down, thereby driving the electric clamp 113 to move up and down. The electric clamp 113 moves downward and approaches the channel 115 until the thin layer plate body 112 enters a certain height in the unfolding cylinder 12. The thin layer plate body 112 contacts the solvent and reaches the set unfolding height. The electric clamp 113 clamps the thin layer plate body 112 and moves it upward to make it separate from the unfolding cylinder 12. The drying component located in the placement groove 111 is turned on to dry the thin layer plate body 112.

[0032] The solvent delivery mechanism includes two groups of solvent delivery components 13, which input the solvent in the developing agent storage cylinder into the developing cylinder 12. The liquid delivery ends of the two groups of solvent delivery components 13 are connected to the developing cylinder 12, and the liquid collection ends of the two groups of solvent delivery components 13 are respectively connected to the first storage cylinder 5 and the second storage cylinder 6. The solvent delivery component 13 includes a solvent delivery pump, which inputs the solvent from the first storage cylinder 5 and the second storage cylinder 6 into the developing cylinder 12, so that the thin layer plate 112 can come into contact with the solvent in the developing cylinder 12.

[0033] The implementation principle of the utility model is as follows: the quantitative preparation device 2 inputs the required solvent into the mixing cylinder 3 for mixing. After the mixing is completed, if the mixed solvent needs to be pre-saturated, the mixed solvent is input into the developing agent storage cylinder through the mixing and conveying mechanism 9. If the solvent needs to be taken in layers, the mixed solvent in the mixing cylinder 3 is first input into the layered static cylinder 4 through the connecting device 7 for static stratification, and the layered suction component then absorbs the layered solvent and inputs it into the developing agent storage cylinder.

[0034] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0035] The preferred embodiments of the present invention are described in detail above in conjunction with the accompanying drawings; however, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, various equivalent transformations can be made to the technical scheme of the present invention, and these equivalent transformations all belong to the protection scope of the present invention.

Claims

1. A fully automatic unfolding instrument, comprising an instrument box, characterized in that: A quantitative preparation device is provided on the instrument box, and the quantitative preparation device is connected to a mixing cylinder provided in the instrument box. A stratified static cylinder, a thin layer plate assembly, a developing agent storage cylinder and a developing cylinder are also provided in the instrument box. The stratified static cylinder is connected to the mixing cylinder via a connecting device. The developing agent storage cylinder body comprises a first storage cylinder and a second storage cylinder, wherein the first storage cylinder and the second storage cylinder are connected to the mixing cylinder via a mixing and conveying mechanism, the first storage cylinder and the second storage cylinder are connected to the layered static cylinder via a layered suction mechanism, and the first storage cylinder and the second storage cylinder are connected to the developing cylinder via a solvent conveying mechanism respectively; The thin layer plate assembly comprises a thin layer plate body, a moving mechanism and a placement groove, wherein the moving mechanism is arranged in the placement groove for storing and placing the thin layer plate body, the placement groove is connected to the deployment cylinder through a channel, and the thin layer plate body enters the deployment cylinder through the channel; The layered absorption mechanism includes a layered absorption component and a layered identification component. When the quantitative preparation device quantitatively inputs the solvent into the mixing cylinder, the mixing delivery mechanism absorbs and distributes the mixed solvent according to the set volume and inputs it into the first storage cylinder and the second storage cylinder. The developing agent in the first storage cylinder first enters the developing cylinder through the solvent delivery mechanism and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder enters the developing cylinder through the solvent delivery mechanism. The thin layer plate enters the developing cylinder driven by the moving mechanism and performs thin layer development according to the set program. If it is necessary to separate The connecting device first inputs the solvent in the mixing cylinder into the stratified static cylinder for static stratification, and the stratified suction component cooperates with the information identified by the stratified identification component to absorb and distribute the stratified solvent according to the set volume into the first storage cylinder and the second storage cylinder. The developing agent in the first storage cylinder first enters the developing cylinder through the solvent delivery mechanism and is pre-saturated according to the set pre-saturation time. After the pre-saturation time is reached, the developing agent in the second storage cylinder enters the developing cylinder through the solvent delivery mechanism, and the thin layer plate enters the developing cylinder driven by the moving mechanism to carry out thin layer development according to the set program.

2. A fully automatic unfolding device according to claim 1, characterized in that: The quantitative preparation device comprises a plurality of liquid storage boxes for storing solvents, each of the liquid storage boxes is connected to the mixing cylinder via a transmission pipeline, and a solenoid valve is arranged on the transmission pipeline.

3. A fully automatic unfolding device according to claim 1, characterized in that: The connecting device comprises a solvent transfer pump, the liquid suction end of the solvent transfer pump is connected to the mixing cylinder through a pipeline, and the liquid infusion end of the solvent transfer pump is connected to the layered static cylinder through a pipeline.

4. A fully automatic unfolding device according to claim 1, characterized in that: The mixing and conveying mechanism comprises a mixing and conveying pump, the liquid suction end of the mixing and conveying pump is connected to the mixing cylinder through a first liquid extraction pipeline, and the liquid delivery end of the mixing and conveying pump is connected to the developing agent storage cylinder through a first T-shaped pipeline; The layered suction assembly includes a layered delivery pump, the liquid suction end of the layered delivery pump is connected to the layered static cylinder through a second liquid extraction pipeline, and the liquid delivery end of the layered delivery pump is connected to the developing agent storage cylinder through a second T-shaped pipeline; The layer recognition component includes a liquid level recognition sensor.

5. A fully automatic unfolding device according to claim 4, characterized in that: The second liquid extraction pipeline includes a fixed pipe, a telescopic pipe and a suction pipe which are arranged in sequence, the two ends of the telescopic pipe are respectively connected to the fixed pipe and the suction pipe, the fixed pipe is connected to the stratified delivery pump, and the suction pipe is located in the stratified static cylinder; A lifting component is also provided on the stratified static cylinder, and the lifting component drives the suction tube to move in the stratified static cylinder.

6. A fully automatic unfolding device according to claim 1, characterized in that: The moving mechanism includes an electric clamp and a position adjustment component, the position adjustment component is arranged in the placement groove, the position adjustment component includes an adjustment screw and an adjustment nut threadedly connected to the adjustment screw, and the electric clamp is installed on the adjustment nut to clamp the thin layer plate.

7. A fully automatic unfolding device according to claim 1, characterized in that: The solvent delivery mechanism includes two groups of solvent delivery components, which input the solvent in the developing agent storage cylinder into the developing cylinder. The liquid delivery ends of the two groups of solvent delivery components are connected to the developing cylinder, and the liquid collection ends of the two groups of solvent delivery components are respectively connected to the first storage cylinder and the second storage cylinder. The solvent delivery components include a solvent delivery pump.

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