Multi-channel detection reagent card
By designing a multi-channel detection reagent card, using multiple parallel sub-channels and drainage diversion structures, simultaneous detection of multiple intense biohazard factors is achieved, solving the problem of low detection efficiency of single-channel card and improving detection efficiency and accuracy.
Patent Information
- Application Number
- CN202420478286.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-12
- Publication Date
- 2025-04-04
- Estimated Expiration
- 2034-03-12
AI Technical Summary
Existing single-channel detection reagent cards can only be screened for one target, resulting in multiple tests for samples containing multiple severe biohazard factors. The detection time is long and the efficiency is low, making it difficult to meet the screening needs.
A multi-channel detection reagent card is designed, and multiple parallel sub-channels are provided in the inner cavity of the housing. The sample is drained into the detection reagent strips in different sub-channels for detection through the drainage structure and the shunt structure for detection, so as to achieve simultaneous detection of multiple targets.
It realizes the detection and screening of various strong biohazard factors in the sample at one time, shortens the detection time, improves the detection efficiency, and avoids the problems of sample spillover and uneven distribution through the shunt structure.
Smart Images

Figure CN222719564U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of immune detection, in particular to a multi-channel detection reagent card. Background Art
[0002] Among the potent biological hazards, the highly pathogenic bacteria and viruses are highly contagious and have high mortality rates. Potent toxins have the risk of causing death or disability in a short period of time with just a small amount. It is crucial to prevent the illegal carrying and spread of potent pathogens into the country and to conduct immediate, on-site screening for sudden public health and safety incidents in places with high mobility and dense crowds, such as customs ports, airports, and railway stations.
[0003] As for biological tracers, the technologies of immunochromatographic detection mainly include colloidal gold immunochromatographic detection technology, upconversion luminescence immunochromatographic detection technology and quantum dot immunochromatographic detection technology. Reagent cards are needed for detection, but the detection reagent cards currently used are mostly single-channel reagent cards, which can only screen one target in a suspicious sample at a time. For samples containing multiple potent biohazard factors, multiple tests are required, resulting in long detection time and low detection efficiency, which is difficult to meet screening needs. Utility Model Content
[0004] Therefore, the technical problem to be solved by the utility model is that the detection reagent cards used in the prior art are mostly single-channel reagent cards, which can only screen one target in a suspicious sample at a time. For samples containing multiple potent biohazard factors, multiple tests are required, resulting in long detection time and low detection efficiency, which is difficult to meet screening needs, thereby providing a multi-channel detection reagent card.
[0005] In order to solve the above technical problems, the technical solution of the utility model is as follows:
[0006] The utility model provides a multi-channel detection reagent card, comprising: a shell, comprising an upper card shell and a lower card shell that are buckled with each other, and a sample injection port is arranged on the upper card shell; a drainage channel is arranged in the inner cavity of the shell, and the drainage channel includes a plurality of sub-channels arranged in parallel; a drainage structure is arranged in the inner cavity of the shell and is located between the sample injection port and the drainage channel, and the drainage structure has a plurality of drainage branches arranged along the circumferential direction of the sample injection port, and each of the drainage branches is adapted to be arranged in one of the sub-channels to drain the sample at the sample injection port to different sub-channels; a shunt structure is arranged in the inner cavity of the shell, and the shunt structure divides the plurality of drainage branches into two clusters, so that the sample at the sample injection port is shunted to both sides and enters the drainage branches contained in different clusters; a detection reagent strip, and the detection reagent strip is arranged at one end of each of the sub-channels away from the drainage structure, and the detection reagent strips in different sub-channels can simultaneously detect different target types such as bacteria, viruses, toxins, etc.
[0007] Furthermore, the drainage structure includes a drainage plate and a drainage groove; the drainage plate is arranged on the inner wall of the upper card shell, and the drainage groove is arranged on the inner wall of the lower card shell. When the upper card shell and the lower card shell are buckled, the drainage plate is inserted into the drainage groove, and the interval between two adjacent drainage plates forms the drainage branch.
[0008] Furthermore, the diversion structure includes a U-shaped diversion plate and a diversion groove; the U-shaped diversion plate is arranged on the inner wall of the upper card shell, and the diversion groove is arranged on the inner wall of the lower card shell. When the upper card shell and the lower card shell are buckled together, the U-shaped diversion plate is inserted in the diversion groove.
[0009] Furthermore, the drainage branches are arranged in parallel, and the drainage branches gradually lengthen from the center line of the reagent card to the edges on both sides.
[0010] Furthermore, a plurality of upwardly convex guide platforms are arranged at intervals on the inner wall of the lower casing, and side baffles are arranged on both sides of each guide platform, and a semi-enclosed space enclosed by the side baffles and the guide platform forms the sub-channel.
[0011] Furthermore, the multi-channel detection reagent card also includes a horizontal baffle, which is arranged on the inner wall of the lower card shell. The horizontal baffle is located at one end of each sub-channel away from the drainage structure, and is used to limit the movement of the detection reagent strip placed in the sub-channel.
[0012] Furthermore, the multi-channel detection reagent card also includes a drainage pad, which is arranged in the inner cavity of the shell, and the drainage pad includes a main body and a plurality of guide parts connected to the main body; the main body is arranged opposite to the sample addition port; the guide part extends into the sub-channel through the drainage branch and is connected to the detection reagent strip to drain the sample added to the sample addition port to the detection reagent strip.
[0013] Furthermore, position matching the detection reagent strip and the drainage pad are provided with limit posts on the inner wall of the upper card shell, and the limit posts press the detection reagent strip and the drainage pad when the upper card shell and the lower card shell are buckled with each other.
[0014] Furthermore, a plurality of annular groove structures are arranged on the inner wall of the lower card shell, and a plurality of rivet structures are adaptively arranged on the inner wall of the upper card shell. When the upper card shell and the lower card shell are buckled with each other, the rivet structures are riveted to the annular groove structures.
[0015] Furthermore, a wide-view detection window is provided on the upper casing at a position adapted for the analysis membrane of the detection reagent strip; and the casing is a rectangular or square casing.
[0016] The technical solution of the utility model has the following advantages:
[0017] The multi-channel detection reagent card provided by the utility model has a plurality of sub-channels arranged in the inner cavity of the shell. When in use, after the sample is added from the sample addition port, the sample is drained into different sub-channels through the drainage branch. Since the detection reagent strips in different sub-channels have different target types, a variety of different potent biological hazard factors such as bacteria, viruses, toxins, etc. in the sample can be detected and screened at one time, which is beneficial to shorten the detection time and improve the detection efficiency. Moreover, since it is necessary to meet the multi-channel detection requirements, the amount of sample used will be larger than that of single-channel detection. By setting a shunt structure, the sample can be shunted so that the sample can flow to the drainage branches of different clusters on both sides in time, which can avoid overflow of the sample and prevent the sample from rushing into the sub-channel of a certain area to cause uneven sample distribution, thereby ensuring the accuracy of multi-channel detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0019] Figure 1It is a schematic diagram of the upper card shell (reverse side) in the multi-channel detection reagent card in the embodiment of the utility model;
[0020] Figure 2 It is a schematic diagram of the upper card shell (front) of the multi-channel detection reagent card in the embodiment of the utility model;
[0021] Figure 3 It is a schematic diagram of the lower card shell of the multi-channel detection reagent card in the embodiment of the utility model;
[0022] Figure 4 It is a schematic diagram of a detection reagent strip in a multi-channel detection reagent card in an embodiment of the utility model.
[0023] 1. Upper card shell; 2. Lower card shell; 301. Sub-channel; 302. Drainage branch; 4. Detection reagent strip; 5. Ring groove structure; 6. Rivet structure; 7. Sample loading port; 8. Wide-view detection window; 9. Limiting column; 10. Drainage plate; 11. Drainage trough; 12. Horizontal baffle; 13. Drainage table; 14. Side baffle; 15. Sample pad; 16. Marking pad; 17. Analysis membrane; 18. Power pad; 19. Adhesive bottom plate; 20. Biocapture probe; 21. Biotracer; 22. Capture antibody A; 23. Detection belt; 24. Quality control belt; 25. Capture antibody B; 26. Secondary antibody; 27. U-shaped shunt plate; 28. shunt trough. DETAILED DESCRIPTION
[0024] The technical solution of the utility model will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0025] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.
[0026] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0027] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.
[0028] like Figures 1 to 3 As shown, this embodiment provides a multi-channel detection reagent card, including: a shell having a sample addition port 7; a drainage channel arranged in the inner cavity of the shell, the drainage channel including a plurality of sub-channels 301 arranged in parallel; a drainage structure arranged in the inner cavity of the shell and located between the sample addition port 7 and the drainage channel, the drainage structure having a plurality of drainage branches 302 arranged along the circumferential direction of the sample addition port 7, each drainage branch 302 is adapted to a sub-channel 301 to drain the sample at the sample addition port 7 to different sub-channels 301; a shunt structure arranged in the inner cavity of the shell, the shunt structure divides the plurality of drainage branches 302 into two clusters, so that the sample at the sample addition port 7 is shunted to both sides and then enters the drainage branches 302 contained in different clusters. For example, the flow splitting structure can equally divide the multiple drainage branches 302 into two left and right clusters, where "cluster" refers to a collective term for multiple closely arranged drainage branches 302, and each cluster has eight drainage branches 302. At this time, there will be sixteen corresponding sub-channels 301. At this time, the multi-channel detection reagent card can detect and screen sixteen kinds of potent biohazard factors at one time.
[0029] Detection reagent strip 4, each subchannel 301 is provided with a detection reagent strip 4 at one end away from the drainage structure, and the detection reagent strips 4 in different subchannels 301 have different target types. Among them, the number of subchannels 301 included in the drainage channel can be between ten and twenty. Among them, the target types of the detection reagent strip 4 include but are not limited to anthrax spores, plague bacteria, Francisella tularensis, Burkholderia pseudomallei, Brucella, Escherichia coli O157, Vibrio cholerae O1 serotype, Vibrio cholerae O139 serotype, Staphylococcus enterotoxin B (SEB), ricin, Abrus toxin, Shiga toxin I, Shiga toxin II, diphtheria toxin, tetanus toxin, botulinum toxin type A, T2 toxin, Zika virus, adenovirus, Ebola virus, etc.
[0030] The multi-channel detection reagent card provided in the present embodiment has a plurality of sub-channels 301 arranged in the inner cavity of the shell. When in use, after the sample is added from the sample addition port 7, the sample is drained into different sub-channels 301 through the drainage branch 302. Since the detection reagent strips 4 in different sub-channels 301 have different target types, a variety of different potent biohazard factors in the sample can be detected and screened at one time, which is beneficial to shorten the detection time and improve the detection efficiency. Moreover, since it is necessary to meet the needs of multi-channel detection, the amount of sample used will be larger than that of single-channel detection. By setting a shunt structure, the sample can be shunted so that the sample can flow to the drainage branches 302 of different clusters on both sides in time, which can avoid overflow of the sample and prevent the sample from rushing into the sub-channel 301 of a certain area, resulting in uneven sample distribution.
[0031] For example, the housing may be a rectangular or square housing, wherein the housing includes an upper housing 1 and a lower housing 2 that are engaged with each other, and the sample adding port 7 is disposed on the upper housing 1. For example, the sample adding port 7 may have a length ranging from 10 mm to 20 mm and a width ranging from 0.5 mm to 1.0 mm.
[0032] The drainage structure includes a drainage sheet 10 and a drainage groove 11; the drainage sheet 10 is arranged on the inner wall of the upper card shell 1, and the drainage groove 11 is arranged on the inner wall of the lower card shell 2. When the upper card shell 1 and the lower card shell 2 are buckled, the drainage sheet 10 is inserted into the drainage groove 11, and the interval between two adjacent drainage sheets 10 forms a drainage branch 302. The drainage sheet 10 has a vertical section, and the shape of the drainage groove 11 is adapted to the drainage sheet 10. One end of the drainage sheet 10 is docked with the downstream sub-channel 301, and the other end is docked with the upstream sample port 7, so that the sample at the sample port 7 can flow more smoothly into the drainage branch 302.
[0033] The diversion structure includes a U-shaped diversion piece 27 and a diversion groove 28; the U-shaped diversion piece 27 is arranged on the inner wall of the upper card shell 1, and the diversion groove 28 is arranged on the inner wall of the lower card shell 2. When the upper card shell 1 and the lower card shell 2 are buckled, the U-shaped diversion piece 27 is inserted into the diversion groove 28. In this way, when the sample flows to the bottom of the U-shaped diversion piece 27, it is blocked and cannot continue to flow upward, and can only be diverted to both sides. For example, the bottom of the U-shaped diversion piece 27 can be straight, and the sample is more easily evenly guided and diverted after flowing to this position, which is conducive to improving the diversion effect.
[0034] Since the sample addition hole is located at the midline position, in order to evenly distribute the added sample to each drainage branch, taking into account the edge effect principle in liquid flow, the drainage branch 302 can be designed to be longer the closer it is to the edge position, so that the straight end of each drainage branch 302 is close to the straight line distance of the edge of the sample addition hole; and the drainage branch is designed to be straight, which is conducive to sample flow and convenient for engineering production injection molding.
[0035] Among them, a plurality of upwardly convex drainage platforms 13 are arranged at intervals on the inner wall of the lower casing 2, and side baffles 14 are arranged on both sides of each drainage platform 13, and the semi-enclosed space surrounded by the side baffles 14 and the drainage platform 13 forms a sub-channel 301. In this way, the upwardly convex drainage platform 13 and the side baffles 14 on both sides can not only prevent the sample liquids in two adjacent sub-channels 301 from interfering with each other, but also play a role in limiting the detection reagent strip 4 placed in the sub-channel 301, preventing the detection reagent strip 4 from shaking left and right.
[0036] The multi-channel detection reagent card further includes a horizontal baffle 12, which is arranged on the inner wall of the lower card shell 2, and the ends of each sub-channel 301 away from the drainage structure are flush with each other. The horizontal baffle 12 is located at the end of each sub-channel 301 away from the drainage structure, and is used to limit the movement of the detection reagent strip 4 placed in the sub-channel 301. In this way, the detection reagent strip 4 is limited by the horizontal baffle 12 to prevent it from moving upward, so as to ensure that the area corresponding to the wide-view detection window is accurately positioned.
[0037] The multi-channel detection reagent card further includes a drainage pad, which is arranged in the inner cavity of the shell, and the drainage pad includes a main body and a plurality of guide parts connected to the main body; the main body is arranged opposite to the sample adding port 7; the guide part extends into the sub-channel 301 through the drainage branch 302 and is connected to the detection reagent strip 4, so as to drain the sample added from the sample adding port 7 to the detection reagent strip 4. When the sample is added from the sample adding port 7, it will drip onto the main body, and then the guide part can transport the sample to the downstream detection reagent strip 4 by adsorption. For example, the guide part is connected to the sample pad 15 of the detection reagent strip 4.
[0038] Among them, the inner wall of the upper card shell 1 is provided with a position adapted to the detection reagent strip 4 and the drainage pad, and the limit column 9 presses the detection reagent strip 4 and the drainage pad when the upper card shell 1 and the lower card shell 2 are buckled together. For example, the number of the limit column 9 can be designed as needed, and the limit column 9 can be a rectangular column or a cylindrical column.
[0039] Among them, a plurality of annular groove structures 5 are arranged on the inner wall of the lower card shell 2, for example, the annular groove structures 5 can be arranged near the edge of the lower card shell 2, and a plurality of rivet structures 6 are arranged on the inner wall of the upper card shell 1, and the rivet structures 6 are riveted to the annular groove structures 5 when the upper card shell 1 and the lower card shell 2 are buckled with each other. Such arrangement enables the upper card shell 1 and the lower card shell 2 to be buckled firmly. Of course, the upper card shell 1 and the lower card shell 2 can also be fixed by screws.
[0040] Among them, a wide-view detection window 8 is provided on the upper card shell 1 at the position of the analysis membrane 17 adapted to the detection reagent strip 4, so that it is convenient to observe the chromatography state and the final detection result. For example, two wide-view detection windows 8 can be provided to respectively observe the detection reagent strip 4 in the sub-channel 301 corresponding to the drainage branch 302 of different clusters.
[0041] like Figure 4 As shown, the test reagent strip 4 includes an adhesive bottom plate 19 and a sample pad 15, a marking pad 16, an analysis membrane 17 and a power pad 18 arranged thereon. The wide-view detection window 8 matches the position of the analysis membrane 17.
[0042] The sample pad 15 may be, but is not limited to, one of absorbent paper, cellulose membrane, glass fiber, non-woven fabric and blood filter membrane.
[0043] The marking pad 16 may be, but is not limited to, one of glass fiber, polyester film and non-woven fabric; a biological capture probe 20 is fixed in the marking pad 16; the biological capture probe 20 is formed by coupling a biological tracer 21 as a tracer and a capture antibody A22 that has the function of directional capture of the antigen to be detected.
[0044] Among them, the analysis membrane 17 can be but not limited to a nitrocellulose membrane or a nylon membrane; wherein, a detection band 23 and a quality control band 24 are arranged on the analysis membrane 17; the detection band 23 is a capture antibody B25 that has the function of directional capture of the antigen to be detected, and the quality control band 24 is a secondary antibody 26 of a target capture antibody A22; a target capture antibody B25 on the detection band 23 as a solid phase capture probe and a target capture antibody A22 in the biological capture probe 20 as a liquid phase recognition probe can form a double antibody sandwich mode to specifically detect a target, and the quality control band 24 can be directly combined with the biological capture probe 20 to control whether the entire chromatography process is normal.
[0045] The power pad 18 may be, but is not limited to, absorbent paper or cellulose film.
[0046] Among them, the adhesive base plate 19 is a hard PVC plate coated with pressure-sensitive glue on one side, which allows the sample pad 15, the marking pad 16, the analysis membrane 17, and the power pad 18 to be overlapped and fixed on the adhesive base plate 19 in a certain way to ensure the continuity of the liquid flow inside the single target detection reagent strip 4.
[0047] The biological capture probe 20 can indicate the presence and concentration of a target in the sample by generating fluorescence of a specific wavelength under ultraviolet light excitation.
[0048] Among them, a certain target capture antibody A and a certain target capture antibody B can be a monoclonal antibody or a polyclonal antibody, and can be the same or different.
[0049] Among them, the potent biohazard factor is a biological tracer 21 based on quantum dots, lanthanide elements and their chelators, colloidal gold, and upconversion luminescent particles, which is covalently coupled with a specific biorecognition probe to form an immunochromatographic biocapture probe 20 to provide a quantitative detection fluorescence source.
[0050] The detection method is as follows:
[0051] Sample pretreatment: Water, food, and fecal samples were enriched with enrichment solution for 5 hours before testing;
[0052] Sample treatment: Evenly mix 1 volume of sample with 1 volume of universal sample treatment solution, which is 0.04M PB with a pH of 7.2, containing 0.027M Na2HPO4, 0.013M NaH2PO4, and 2% SDS.
[0053] Add sample: Place the reagent card on a horizontal table, take 3 mL of the treated sample and add it to the sample injection port 7;
[0054] Chromatographic reaction: After adding the sample, the reagent card is placed on a horizontal table and left to stand for 8 minutes until the chromatography reaction is completed;
[0055] Result interpretation: The reagent card is placed in the quantum dot detector for one-time scanning and imaging, concentration calculation, and background interference is removed based on the ratio of detection band 23 / quality control band 24 and the detection value is displayed.
[0056] Wherein, if the quality control strip 24 has a value, the result is determined to be valid, and if the value of the quality control strip 24 is 0, the result is determined to be invalid;
[0057] Quantitative results: In the valid results, the ratio of sample test band 23 / quality control band 24 represents the detection amount of a certain target, which is calculated by fitting with the built-in standard curve to finally display the numerical quantitative results of ten targets.
[0058] In summary, the multi-channel detection reagent card in the present application, with the structural design of the multi-channel detection reagent card, combined with the single-target detection reagent strip 4, can achieve quantitative detection of more than 10 potent biohazard factor targets within 8 minutes with one sample loading, meeting the needs of on-site and multi-target; based on the design of the multi-parallel flow channel detection reagent card structure and relying on the characteristics of the high quantum yield biological tracer 21, it meets the needs of the immunochromatographic detection structure while achieving high space utilization, laying the foundation for handheld and portable detection equipment.
[0059] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention of the utility model.
Claims
1. A multi-channel detection reagent card, characterized in that: include: The housing comprises an upper card shell (1) and a lower card shell (2) which are engaged with each other, and a sample adding port (7) is provided on the upper card shell (1); A drainage channel is arranged in the inner cavity of the shell, and the drainage channel includes a plurality of sub-channels (301) arranged in parallel; a drainage structure, arranged in the inner cavity of the shell and located between the sample addition port (7) and the drainage channel, the drainage structure having a plurality of drainage branches (302) arranged along the circumferential direction of the sample addition port (7), each of the drainage branches (302) being adapted to be arranged in one of the sub-channels (301) so as to drain the sample at the sample addition port (7) into different sub-channels (301); A flow splitting structure is arranged in the inner cavity of the shell, wherein the flow splitting structure (302) divides the plurality of drainage branches into two clusters, so that the sample at the sample adding port (7) is split to both sides and then enters the drainage branches (302) contained in different clusters; A detection reagent strip (4), wherein the detection reagent strip (4) is disposed at one end of each subchannel (301) away from the drainage structure, and the detection reagent strips (4) in different subchannels (301) can simultaneously detect different target types such as bacteria, viruses, and toxins; The flow-dividing structure comprises a U-shaped flow-dividing sheet (27) and a flow-dividing groove (28); The U-shaped flow dividing piece (27) is arranged on the inner wall of the upper card shell (1), and the flow dividing groove (28) is arranged on the inner wall of the lower card shell (2), and when the upper card shell (1) and the lower card shell (2) are buckled together, the U-shaped flow dividing piece (27) is inserted into the flow dividing groove (28); The bottom of the U-shaped diverter is straight; The drainage branch is designed to be straight line.
2. The multi-channel detection reagent card according to claim 1, characterized in that: The drainage structure comprises a drainage sheet (10) and a drainage groove (11); The drainage sheet (10) is arranged on the inner wall of the upper card shell (1), and the drainage groove (11) is arranged on the inner wall of the lower card shell (2). When the upper card shell (1) and the lower card shell (2) are buckled together, the drainage sheet (10) is inserted into the drainage groove (11), and the interval between two adjacent drainage sheets (10) forms the drainage branch (302).
3. The multi-channel detection reagent card according to claim 1, characterized in that: The drainage branches (302) are arranged in parallel, and the drainage branches (302) gradually lengthen from the center line of the reagent card to the edges on both sides.
4. The multi-channel detection reagent card according to claim 1, characterized in that: A plurality of upwardly convex guide platforms (13) are arranged at intervals on the inner wall of the lower casing (2), and side baffles (14) are arranged on both sides of each guide platform (13). The semi-enclosed space enclosed by the side baffles (14) and the guide platform (13) forms the sub-channel (301).
5. The multi-channel detection reagent card according to claim 4, characterized in that: It also includes a horizontal baffle (12) arranged on the inner wall of the lower casing (2), and the horizontal baffle (12) is located at one end of each sub-channel (301) away from the drainage structure, and is used to limit the movement of the detection reagent strip (4) placed in the sub-channel (301).
6. The multi-channel detection reagent card according to claim 1, characterized in that: Also included is a drainage pad, which is disposed in the inner cavity of the shell, and the drainage pad includes a main body and a plurality of guide parts connected to the main body; The main body is arranged facing the sample adding port (7); The guide portion extends into the sub-channel (301) through the drainage branch (302) and is connected to the detection reagent strip (4) to drain the sample added to the sample addition port (7) to the detection reagent strip (4).
7. The multi-channel detection reagent card according to claim 6, characterized in that: Limiting posts (9) are provided on the inner wall of the upper card shell (1) at positions matching the detection reagent strip (4) and the drainage pad. When the upper card shell (1) and the lower card shell (2) are mutually buckled, the limiting posts (9) press the detection reagent strip (4) and the drainage pad.
8. The multi-channel detection reagent card according to claim 1, characterized in that: A plurality of annular groove structures (5) are arranged on the inner wall of the lower card shell (2), and a plurality of rivet structures (6) are arranged on the inner wall of the upper card shell (1) in a matching manner. When the upper card shell (1) and the lower card shell (2) are buckled together, the rivet structures (6) and the annular groove structures (5) are riveted together.
9. The multi-channel detection reagent card according to claim 1, characterized in that: A wide-view detection window (8) is provided on the upper card shell (1) at the position of the analysis membrane (17) adapted to the detection reagent strip (4); The shell is a rectangular or square shell.
Citation Information
Cited By
Multi-channel synchronous detection reagent card
CN120214303A