A control circuit for an optogenetic system

Abstract

The utility model discloses a control circuit for an optogenetic system, including: a power module for supplying power to the entire control circuit; a main control module for receiving signals and sending signals after processing; multiple LED constant current control modules for driving multiple LEDs; an optical camera trigger module for controlling the exposure of the optical camera; a galvanometer control module for outputting a voltage of +5V to ‑5V; the main control module is electrically connected to the power module, the LED constant current control module, the optical camera trigger module, and the galvanometer control module, respectively. The control circuit for an optogenetic system of the utility model has a simple structure and is easy to use. Through the coordinated setting between the power module, the main control module, the LED constant current control module, the optical camera trigger module, and the galvanometer control module, the three independently controlled LEDs, one camera, and two galvanometers are integrated into the same drive circuit, reducing the structural complexity of the entire system.

Description

Technical Field

[0001] The utility model relates to the technical field of optogenetics systems, and in particular to a control circuit for optogenetics systems. Background Art

[0002] With the development of modern optics and biomedicine, a medical technology that uses lasers in different sequences to stimulate different parts of the mouse brain, uses a high-performance camera to connect the mouse brain through multiple optical fibers to shoot videos of the corresponding parts, obtains camera data on the host computer, and calculates the light signal intensity of different parts through a specific image algorithm. The signal intensity is further analyzed and processed by an algorithm to diagnose the health of the mouse brain. This technology is called optogenetics. The optogenetic system involves the control of multiple modules, including multiple LEDs of different wavelengths, a high-performance camera dedicated to optics, and two galvanometers. Existing optogenetic systems usually use Python to write a simple host computer program on a PC to control multiple LEDs, cameras, and galvanometers respectively, and perform data processing through the host computer software provided by the camera manufacturer. This solution is not only inefficient and complicated to operate, but also very easy to cause confusion in the frame synchronization of LED control and camera shooting, resulting in experimental data errors.

[0003] Based on the above situation, the utility model proposes a control circuit for an optogenetic system, which can effectively solve the above problems. Utility Model Content

[0004] The purpose of the utility model is to provide a control circuit for an optogenetic system. The control circuit for an optogenetic system of the utility model has a simple structure and is easy to use. Through the coordination of a power module, a main control module, an LED constant current control module, an optical camera trigger module, and a galvanometer control module, three independently controlled LEDs, one camera, and two galvanometers are integrated into the same drive circuit, thereby reducing the structural complexity of the entire system.

[0005] The utility model is realized by the following technical solutions:

[0006] A control circuit for an optogenetic system, comprising:

[0007] Power module, used to supply power to the entire control circuit;

[0008] The main control module is used to receive signals and send them after processing;

[0009] Multiple LED constant current control modules, used to drive multiple LEDs;

[0010] An optical camera trigger module, used to control the exposure of the optical camera;

[0011] Galvanometer control module, used to output voltage of +5V to -5V;

[0012] USB serial communication module, used for communication between hardware and host computer;

[0013] Wherein, the main control module is electrically connected to the power supply module, the LED constant current control module, the optical camera trigger module, and the galvanometer control module respectively.

[0014] The purpose of the utility model is to provide a control circuit for an optogenetic system. The control circuit for an optogenetic system of the utility model has a simple structure and is easy to use. Through the coordination of a power module, a main control module, an LED constant current control module, an optical camera trigger module, and a galvanometer control module, three independently controlled LEDs, one camera, and two galvanometers are integrated into the same drive circuit, thereby reducing the structural complexity of the entire system.

[0015] Preferably, the number of the LED constant current control modules is three.

[0016] Preferably, the LED constant current control module includes an LED driver chip U1, an inductor L1, a diode D1, a first electrolytic capacitor E1, a first capacitor C1, a second capacitor C2, a third capacitor C3, a fourth capacitor C4, a fifth capacitor C5, a first resistor R1, a second resistor R2, a third resistor R3, and a fourth resistor R4. The VCC pin of the LED driver chip U1 is electrically connected to one end of the first resistor R1, and the other end of the first resistor R1 is electrically connected to the TON pin of the LED driver chip U1. The EN pin of the LED driver chip U1 is electrically connected to the second resistor R2 and one end of the first capacitor C1 respectively, and the other end of the first capacitor C1 is electrically connected to one end of the third resistor R3. The other end of the third resistor R3 is electrically connected to the FB pin of the LED driver chip U1. The LX pin of the LED driver chip U1 is electrically connected to one end of the second capacitor C2, the cathode of the diode D1, and one end of the inductor L1, respectively; the other end of the second capacitor C2 is electrically connected to the BOOT pin of the LED driver chip U1; the GND pin of the LED driver chip U1 is electrically connected to the anode of the diode D1 and one end of the third capacitor C3, respectively; the VDD pin of the LED driver chip U1 is electrically connected to the other end of the third capacitor C3; the other end of the inductor L1 is electrically connected to one end of the first electrolytic capacitor E1, one end of the fourth capacitor C4, one end of the fifth capacitor C5, and one end of the fourth resistor R4, respectively; the other end of the first electrolytic capacitor E1 is electrically connected to the other end of the fourth capacitor C4, the other end of the fifth capacitor C5, and the other end of the fourth resistor R4, respectively.

[0017] Preferably, the optical camera trigger module includes a connector P1, a sixth capacitor C6, and a seventh capacitor C7, pin 6 of the connector P1 is electrically connected to one end of the sixth capacitor C6, pin 5 of the connector P1 is electrically connected to one end of the seventh capacitor C7, and pin 4 of the connector P1 is electrically connected to the other end of the sixth capacitor C6 and the other end of the seventh capacitor C7, respectively.

[0018] Preferably, the galvanometer control module includes a negative voltage generator U2, a second electrolytic capacitor E2, a third electrolytic capacitor E3, and an eighth capacitor C8, the CAP+ pin of the negative voltage generator U2 is electrically connected to one end of the second electrolytic capacitor E2, the other end of the second electrolytic capacitor E2 is electrically connected to the CAP- pin of the negative voltage generator U2, the V+ pin of the negative voltage generator U2 is electrically connected to one end of the eighth capacitor C8, the other end of the eighth capacitor C8 is electrically connected to the LV pin of the negative voltage generator U2, and the OUT pin of the negative voltage generator U2 is electrically connected to the third electrolytic capacitor E3.

[0019] Preferably, the main control module is a single chip microcomputer of model STM32F407ZGT6.

[0020] Preferably, the model of the LED driver chip U1 is IS31LT3953B.

[0021] Preferably, the model of the negative voltage generator U2 is MAX660.

[0022] Compared with the prior art, the utility model has the following advantages and beneficial effects:

[0023] The control circuit for the optogenetics system of the utility model has a simple structure and is easy to use. Through the coordinated setting of the power module, the main control module, the LED constant current control module, the optical camera trigger module, and the galvanometer control module, the originally independently controlled three-way LED, one-way camera, and two galvanometers are integrated into the same drive circuit, thereby reducing the structural complexity of the entire system. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic block diagram of the circuit of the utility model;

[0025] Figure 2 This is a circuit schematic diagram of the LED constant current control module of the utility model;

[0026] Figure 3 This is a circuit schematic diagram of the optical camera trigger module of the utility model;

[0027] Figure 4 This is a circuit schematic diagram of the galvanometer control module of the utility model. DETAILED DESCRIPTION

[0028] In order to enable those skilled in the art to better understand the technical solution of the utility model, the preferred implementation scheme of the utility model is described below in conjunction with specific embodiments. However, it should be understood that the drawings are only used for illustrative purposes and cannot be understood as a limitation on this patent. In order to better illustrate this embodiment, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of the actual product. For those skilled in the art, it is understandable that some well-known structures and their descriptions in the drawings may be omitted. The positional relationship described in the drawings is only used for illustrative purposes and cannot be understood as a limitation on this patent.

[0029] The technical features such as the power module described in the utility model (the constituent units / elements of the utility model), unless otherwise specified, are obtained from conventional commercial channels or manufactured by conventional methods. Their specific structures, working principles, and possible control methods and spatial layout methods can be selected conventionally in the art and should not be regarded as the innovative points of the utility model. For those skilled in the art, it is understandable that the utility model patent will not be further elaborated.

[0030] Embodiment 1:

[0031] like Figures 1 to 4 As shown, the utility model provides a control circuit for an optogenetic system, comprising:

[0032] Power module 1, used to supply power to the entire control circuit;

[0033] Main control module 2, used to receive signals and send them after processing;

[0034] Multiple LED constant current control modules 3, used to drive multiple LEDs;

[0035] An optical camera trigger module 4, used to control the exposure of the optical camera;

[0036] The galvanometer control module 5 is used to output a voltage of +5V to -5V;

[0037] The USB serial port communication module 6 uses the USB analog serial port communication function to realize the communication between the hardware and the host computer.

[0038] The main control module 2 is electrically connected to the power module 1 , the LED constant current control module 3 , the optical camera trigger module 4 , and the galvanometer control module 5 , respectively.

[0039] Embodiment 2:

[0040] like Figures 1 to 4 As shown, the utility model provides a control circuit for an optogenetic system, comprising:

[0041] Power module 1 is used to power the entire control circuit; the operating voltage of the MCU is 3.3V, the system input voltage is 12V, and the working voltage of the LED driver module is 12V, so 12V needs to be converted to 3.3V. Since the maximum operating current of the LED control module is 1.2A, and the LED power output has high requirements for linearity, a low-efficiency linear voltage regulator is not used, and a high-efficiency DC-DC switching circuit is used. A power supply specification of 12V1.2A can be provided to meet the needs;

[0042] Main control module 2 is used to receive signals and send them after processing; the main control MCU is the STM32F4 series, which mainly realizes the high-frequency start and stop of all modules (up to 1000HZ) and ensures strict frame synchronization between different modules.

[0043] Multiple LED constant current control modules 3, used to drive multiple LEDs;

[0044] An optical camera trigger module 4, used to control the exposure of the optical camera;

[0045] The galvanometer control module 5 is used to output a voltage of +5V to -5V;

[0046] The USB serial port communication module 6 uses the USB analog serial port communication function to realize the communication between the hardware and the host computer.

[0047] The main control module 2 is electrically connected to the power module 1 , the LED constant current control module 3 , the optical camera trigger module 4 , and the galvanometer control module 5 , respectively.

[0048] The number of the LED constant current control modules 3 is three.

[0049] Further, in another embodiment, the LED constant current control module 3 includes an LED driver chip U1, an inductor L1, a diode D1, a first electrolytic capacitor E1, a first capacitor C1, a second capacitor C2, a third capacitor C3, a fourth capacitor C4, a fifth capacitor C5, a first resistor R1, a second resistor R2, a third resistor R3, and a fourth resistor R4. The VCC pin of the LED driver chip U1 is electrically connected to one end of the first resistor R1, and the other end of the first resistor R1 is electrically connected to the TON pin of the LED driver chip U1. The EN pin of the LED driver chip U1 is electrically connected to one end of the second resistor R2 and the first capacitor C1 respectively. The other end of the first capacitor C1 is electrically connected to one end of the third resistor R3, and the other end of the third resistor R3 is electrically connected to the LED driver chip The FB pin of the LED driver chip U1 is electrically connected, the LX pin of the LED driver chip U1 is electrically connected to one end of the second capacitor C2, the cathode of the diode D1, and one end of the inductor L1, the other end of the second capacitor C2 is electrically connected to the BOOT pin of the LED driver chip U1, the GND pin of the LED driver chip U1 is electrically connected to the anode of the diode D1 and one end of the third capacitor C3, the VDD pin of the LED driver chip U1 is electrically connected to the other end of the third capacitor C3, the other end of the inductor L1 is electrically connected to one end of the first electrolytic capacitor E1, one end of the fourth capacitor C4, one end of the fifth capacitor C5, and one end of the fourth resistor R4, and the other end of the first electrolytic capacitor E1 is electrically connected to the other end of the fourth capacitor C4, the other end of the fifth capacitor C5, and the other end of the fourth resistor R4.

[0050] LED constant current control module 3 requires higher output power, high frequency switching and linearity of output power and voltage. It adopts the imported RCD-24LED driver module, which supports PWM wave duty cycle to control LED output power.

[0051] Furthermore, in another embodiment, the optical camera trigger module 4 includes a connector P1, a sixth capacitor C6, and a seventh capacitor C7, pin 6 of the connector P1 is electrically connected to one end of the sixth capacitor C6, pin 5 of the connector P1 is electrically connected to one end of the seventh capacitor C7, and pin 4 of the connector P1 is electrically connected to the other end of the sixth capacitor C6 and the other end of the seventh capacitor C7, respectively.

[0052] The optical camera trigger module 4 uses the MCU hardware resources to achieve rising edge output of precise frequency and control the exposure of the optical camera.

[0053] Further, in another embodiment, the galvanometer control module 5 includes a negative voltage generator U2, a second electrolytic capacitor E2, a third electrolytic capacitor E3, and an eighth capacitor C8, the CAP+ pin of the negative voltage generator U2 is electrically connected to one end of the second electrolytic capacitor E2, the other end of the second electrolytic capacitor E2 is electrically connected to the CAP- pin of the negative voltage generator U2, the V+ pin of the negative voltage generator U2 is electrically connected to one end of the eighth capacitor C8, the other end of the eighth capacitor C8 is electrically connected to the LV pin of the negative voltage generator U2, and the OUT pin of the negative voltage generator U2 is electrically connected to the third electrolytic capacitor E3.

[0054] The galvanometer control module 5 uses two DACs provided by the MCU and an external op amp to implement voltage offset and amplification functions, achieving continuous -4V to +4V voltage output requirements, and the maximum control frequency can reach 1000HZ, meeting the control requirements of the galvanometer.

[0055] Furthermore, in another embodiment, the main control module 2 is a single chip microcomputer of model STM32F407ZGT6.

[0056] Furthermore, in another embodiment, the model of the LED driver chip U1 is IS31LT3953B.

[0057] Furthermore, in another embodiment, the negative voltage generator U2 is of model MAX660.

[0058] According to the description and drawings of the present invention, those skilled in the art can easily manufacture or use the control circuit for an optogenetic system of the present invention, and can produce the positive effects recorded in the present invention.

[0059] Unless otherwise specified, in the present invention, the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicating orientation or positional relationships are based on the orientation or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation. Therefore, the terms describing the orientation or positional relationship in the present invention are only used for illustrative purposes and cannot be understood as limitations on this patent. For ordinary technicians in this field, the specific meanings of the above terms can be understood in conjunction with the drawings and according to specific circumstances.

[0060] Unless otherwise specified and limited, in the present invention, the terms "disposed", "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0061] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any simple modification or equivalent changes made to the above embodiments based on the technical essence of the present invention shall fall within the protection scope of the present invention.

Claims

1. A control circuit for an optogenetic system, characterized in that: include: Power module, used to supply power to the entire control circuit; The main control module is used to receive signals and send them after processing; Multiple LED constant current control modules, used to drive multiple LEDs; An optical camera trigger module, used to control the exposure of the optical camera; Galvanometer control module, used to output voltage of +5V to -5V; USB serial communication module, used for communication between hardware and host computer; Wherein, the main control module is electrically connected to the power supply module, the LED constant current control module, the optical camera trigger module, and the galvanometer control module respectively.

2. The control circuit for an optogenetic system according to claim 1, characterized in that: The number of the LED constant current control modules is three.

3. The control circuit for an optogenetic system according to claim 1, characterized in that: The LED constant current control module includes an LED driver chip U1, an inductor L1, a diode D1, a first electrolytic capacitor E1, a first capacitor C1, a second capacitor C2, a third capacitor C3, a fourth capacitor C4, a fifth capacitor C5, a first resistor R1, a second resistor R2, a third resistor R3, and a fourth resistor R4. The VCC pin of the LED driver chip U1 is electrically connected to one end of the first resistor R1, and the other end of the first resistor R1 is electrically connected to the TON pin of the LED driver chip U1. The EN pin of the LED driver chip U1 is electrically connected to one end of the second resistor R2 and the first capacitor C1 respectively. The other end of the first capacitor C1 is electrically connected to one end of the third resistor R3, and the other end of the third resistor R3 is electrically connected to the FB pin of the LED driver chip U1. The LX pin of the LED driver chip U1 is electrically connected to one end of the second capacitor C2, the cathode of the diode D1, and one end of the inductor L1, respectively; the other end of the second capacitor C2 is electrically connected to the BOOT pin of the LED driver chip U1; the GND pin of the LED driver chip U1 is electrically connected to the anode of the diode D1 and one end of the third capacitor C3, respectively; the VDD pin of the LED driver chip U1 is electrically connected to the other end of the third capacitor C3; the other end of the inductor L1 is electrically connected to one end of the first electrolytic capacitor E1, one end of the fourth capacitor C4, one end of the fifth capacitor C5, and one end of the fourth resistor R4, respectively; the other end of the first electrolytic capacitor E1 is electrically connected to the other end of the fourth capacitor C4, the other end of the fifth capacitor C5, and the other end of the fourth resistor R4, respectively.

4. The control circuit for an optogenetic system according to claim 1, characterized in that: The optical camera trigger module includes a connector P1, a sixth capacitor C6, and a seventh capacitor C7. Pin 6 of the connector P1 is electrically connected to one end of the sixth capacitor C6, pin 5 of the connector P1 is electrically connected to one end of the seventh capacitor C7, and pin 4 of the connector P1 is electrically connected to the other end of the sixth capacitor C6 and the other end of the seventh capacitor C7, respectively.

5. The control circuit for an optogenetic system according to claim 1, characterized in that: The galvanometer control module includes a negative voltage generator U2, a second electrolytic capacitor E2, a third electrolytic capacitor E3, and an eighth capacitor C8. The CAP+ pin of the negative voltage generator U2 is electrically connected to one end of the second electrolytic capacitor E2, the other end of the second electrolytic capacitor E2 is electrically connected to the CAP- pin of the negative voltage generator U2, the V+ pin of the negative voltage generator U2 is electrically connected to one end of the eighth capacitor C8, the other end of the eighth capacitor C8 is electrically connected to the LV pin of the negative voltage generator U2, and the OUT pin of the negative voltage generator U2 is electrically connected to the third electrolytic capacitor E3.

6. The control circuit for an optogenetic system according to claim 1, characterized in that: The main control module is a single chip microcomputer of model STM32F407ZGT6.

7. The control circuit for an optogenetic system according to claim 3, characterized in that: The model of the LED driver chip U1 is IS31LT3953B.

8. The control circuit for an optogenetic system according to claim 5, characterized in that: The model of the negative voltage generator U2 is MAX660.

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