Mongolian medicine syndrome type animal model establishing device

Abstract

The utility model belongs to the technical field of animal model building, and particularly relates to a Mongolian medicine syndrome type animal model building device which comprises a bottom butt joint ring, an air supply structure is arranged on the bottom butt joint ring, a net cage is fixedly connected to the top of the bottom butt joint ring, and a bottom supporting net is installed on the inner wall of the bottom butt joint ring. The bottom of the bottom butt joint ring is detachably connected with an excrement collecting frame in a clamped mode. A top cover is fixedly installed on the top of the net cage, the mouse trapping device further comprises a light-proof sleeve bag, a lighting lamp and a loudspeaker, the mouse is stimulated in multiple aspects, then the autonomic nervous system and the enteric nervous system of the gastrointestinal tract are influenced, and therefore the mouse trapping device can be used for trapping mice. Therefore, the release of gastrointestinal hormones is directly or indirectly influenced so as to regulate the sensory and motor functions of gastrointestinal tracts.

Description

Technical Field

[0001] The utility model belongs to the technical field of animal model establishment, and particularly relates to a device for establishing a Mongolian medicine syndrome animal model. Background Art

[0002] With the increasing development of modern research on Mongolian medicine, research on animal models combined with Mongolian medical symptoms has gradually received widespread attention. In Mongolian medicine theory, Heyi diffuse Xila disease is a cold Xila disease, which is mainly caused by the excessive Heyi and the conflict with the digestive Xila, resulting in the spread of Xila. Its functional disorder forms Heyi diffuse Xila disease. Clinical manifestations include loss of appetite, digestive disorders, small intestinal colic, abdominal distension and bowel sounds, dry stool, yellow urine and other symptoms. The mechanism of Heyi diffuse Xila disease in Mongolian medicine theory is that Heyi is too strong and descends into the digestive Xila site - the stomach and the beginning of the small intestine, causing the disorder of the Heyi meridian connecting the stomach and small intestine and the loss of its inductive nerve function, thus affecting the normal digestive function and causing Heyi diffuse Xila disease. Therefore, it is preliminarily inferred that the two Heyi meridians connecting the small intestine and the one Bada Gan meridian connecting the stomach in Mongolian medicine theory are similar to the sympathetic and parasympathetic peripheral nerves in physiological structure and function, and the digestive Xila blown by the fire-adjusting Heyi is similar in nature and function to the gastric and intestinal fluids that are regulated by the autonomic nervous system to play a digestive role, and the pathogenesis, etiology and clinical symptoms of Heyi diffuse Xila disease are similar to those of FD.

[0003] Based on the pathogenic principle of Hei's sexually spread Xila disease in Mongolian medicine and the pathological evolution process studied using mice as experimental subjects, the present application provides a device for establishing an animal model of Mongolian medicine syndrome. Utility Model Content

[0004] 1. Technical issues to be resolved

[0005] The utility model provides a device for establishing a Mongolian medicine syndrome animal model in order to solve the above problems.

[0006] (II) Technical content

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] A device for establishing a Mongolian medicine syndrome animal model comprises a bottom docking ring, an air delivery structure is arranged on the bottom docking ring, a net cage is fixedly connected to the top of the bottom docking ring, a bottom support net is installed on the inner wall of the bottom docking ring, and a feces collection frame is detachably clamped on the bottom of the bottom docking ring;

[0009] A top cover is fixedly installed on the top of the net cage.

[0010] Furthermore, an air duct is arranged on the bottom docking ring, the bottom of the mesh cage is fixedly connected to the top of the air duct, and an air outlet hole communicating with the inner cavity of the air duct is arranged on the inner wall of the bottom docking ring;

[0011] The air delivery structure comprises a fan and an air duct pipe, the air outlet of the air duct pipe is connected to the inner cavity of the air duct, and the air inlet of the air duct pipe is connected to the air outlet end of the fan.

[0012] Furthermore, a funnel-shaped storage tube is connected to the tube wall of the air duct tube, the top of the storage tube is open and has a sealing cover, the bottom of the storage tube is provided with a water outlet, the bottom of the storage tube is threadedly connected to a collecting tube, and the collecting tube is connected to the storage tube through the water outlet.

[0013] Further, the bottom support mesh is threadedly connected to the inner wall of the bottom docking ring;

[0014] Two grid plates are symmetrically installed on the bottom support net, a separation portion is formed between the two grid plates and the bottom support net, and the two grid plates are slidably connected to the same baffle.

[0015] Furthermore, a card slot is provided on the inner wall of the bottom docking ring, a slider is slidably connected in the card slot, a card strip adapted to the card slot is provided on the inner wall of the feces collection frame, a card connector is provided on the top of the card strip, and the card connector is card-connected in the corresponding card slot.

[0016] Furthermore, a light-proof bag is provided on the side wall of the top cover, the top of the bag is fixedly connected to the top cover, and a constriction portion is provided on the bottom.

[0017] Furthermore, a limit rod is circumferentially arranged on the top of the air duct.

[0018] Furthermore, a lighting lamp is installed at the bottom of the top cover.

[0019] Furthermore, the net cage is provided with an opening for placing the animal.

[0020] Furthermore, a speaker is installed at the bottom of the top cover.

[0021] (III) Beneficial effects

[0022] Compared with the prior art, the beneficial effects of the utility model are:

[0023] 1. In the present invention, mice are stimulated in many aspects to affect the autonomic nervous system and enteric nervous system of the gastrointestinal tract, thereby directly or indirectly affecting the release of gastrointestinal hormones to regulate the sensory and motor functions of the gastrointestinal tract.

[0024] Second, in the present invention, when the feces collecting frame needs to be removed, it is only necessary to press the slider inwards, and the card connector is squeezed out of the card slot through the slider, and then the frame can be removed, which is convenient and quick.

[0025] 3. In the utility model, when it is necessary to lower the temperature inside the mesh cage, ice cubes are placed in the storage tube, and the heating function of the fan is turned off. When the air passes through the storage tube, the ice cubes can absorb the heat in the air, so that the temperature of the air after passing through the storage tube is reduced, thereby achieving cooling of the inside of the mesh cage. The air can be evenly delivered through the provided air outlet to prevent local overheating or overcooling.

[0026] Fourth, in the present invention, the isolation part can be used to limit the position of the mouse, so that the inspector can use tools such as hemostatic forceps to clamp the mouse's tail and irritate the mouse.

[0027] 5. In the present invention, the bagging and lighting are arranged to facilitate the inspectors to adjust the brightness inside the cage at any time to meet different inspection requirements. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 A three-dimensional schematic diagram of the utility model as a whole;

[0029] Figure 2 It is a schematic diagram of the opening in the utility model;

[0030] Figure 3 It is an exploded schematic diagram of the midsole docking ring and the feces collection frame of the utility model;

[0031] Figure 4 It is a partial cross-sectional view of the utility model;

[0032] Figure 5 for Figure 4 A local enlarged schematic diagram of the middle A;

[0033] Figure 6 It is a schematic diagram of the bottom support net, grid plate, isolation part and baffle in the utility model;

[0034] Figure 7 It is a schematic diagram of the wind delivery structure of the utility model;

[0035] Figure 8 It is a schematic diagram of the top cover in the utility model;

[0036] Fig. 9 This is a schematic diagram of the net cage wrapped with a bag in the utility model;

[0037] Fig.10 for Fig. 9 A local enlarged schematic diagram of point B in the middle.

[0038] In the figure: 1, bottom docking ring; 2, net cage; 3, feces collection frame; 4, top cover; 5, air duct; 6, air outlet; 7, fan; 8, air duct pipe; 9, storage pipe; 10, cover; 11, water outlet; 12, collection pipe; 13, bottom support net; 14, grille plate; 15, isolation part; 16, baffle; 17, slot; 18, slider; 19, clamping strip; 20, clamp joint; 21, bag; 22, constriction part; 23, limit rod; 24, lighting; 25, speaker; 26, opening. DETAILED DESCRIPTION

[0039] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0040] Embodiment 1

[0041] like Figure 1-Figure 10 As shown, a device for establishing a Mongolian medicine syndrome animal model comprises a bottom docking ring 1, an air delivery structure is arranged on the bottom docking ring 1, and a net cage 2 is fixedly connected to the top of the bottom docking ring 1. Figure 2 As shown, the cage 2 is provided with an opening 26 for placing animals, so that the staff can take and place the mice. The inner wall of the bottom docking circle 1 is provided with a bottom support net 13, as shown in FIG. Figure 1 As shown, the bottom of the bottom docking ring 1 is detachably connected to the feces collection frame 3, specifically: Figure 3-Figure 5 As shown, a card slot 17 is provided on the inner wall of the bottom docking ring 1, and a slider 18 is slidably connected in the card slot 17. A card strip 19 adapted to the card slot 17 is provided on the inner wall of the feces collection frame 3, and a card joint 20 is provided on the top of the card strip 19. The card joint 20 is carded in the corresponding card slot 17. When installing, the card strip 19 is inserted along the bottom of the bottom docking ring 1. At this time, the inner wall of the bottom docking ring 1 will squeeze the card joint 20, and the card strip 19 will produce elastic deformation and bend inward. When the clamping joint 20 moves to the side of the clamping groove 17, the squeezing force of the inner wall of the bottom docking ring 1 on the clamping joint 20 disappears, and the clamping strip 19 is reset, thereby moving the clamping joint 20 into the clamping groove 17. At the same time, the clamping joint 20 pushes the slider 18 outward for a distance, and the clamping of the feces collection frame 3 is completed. When the feces collection frame 3 needs to be removed, it is only necessary to press the slider 18 inward to squeeze the clamping joint 20 out of the clamping groove 17 through the slider 18, thereby completing the disassembly;

[0042] like Figure 1 As shown, a top cover 4 is fixedly installed on the top of the net cage 2.

[0043] Furthermore, in order to detect whether mice like heat or not, Figure 6 As shown, an air duct 5 is provided on the bottom docking ring 1, the bottom of the mesh cage 2 is fixedly connected to the top of the air duct 5, and an air outlet 6 connected to the inner cavity of the air duct 5 is provided on the inner wall of the air duct 5;

[0044] like Figure 7 As shown, the air delivery structure includes a fan 7 and an air duct pipe 8, the air outlet of the air duct pipe 8 is connected to the inner cavity of the air duct 5, and the air inlet of the air duct pipe 8 is connected to the air outlet end of the fan 7. The fan 7 can heat the external wind and send the hot air to the air duct 5 through the air duct pipe 8, and then send the hot air out through the air outlet 6 to increase the temperature inside the mesh cage 2.

[0045] Further, such as Figure 7 As shown, a funnel-shaped storage tube 9 is connected to the tube wall of the air duct tube 8. When it is necessary to lower the temperature inside the mesh cage 2, ice cubes are put into the storage tube 9 and the heating function of the fan 7 is turned off. When the air passes through the storage tube 9, the ice cubes can absorb the heat in the air, so that the temperature of the air after passing through the storage tube 9 is reduced, thereby achieving cooling of the inside of the mesh cage 2. The air can be evenly delivered through the arranged air outlet 6 to prevent local overheating or overcooling. The top of the storage tube 9 is open and is clamped with a cover 10 to prevent wind from leaking from the top of the storage tube 9. A water outlet 11 is provided at the bottom of the storage tube 9. A collecting tube 12 is threadedly connected to the bottom of the storage tube 9. The collecting tube 12 is connected to the storage tube 9 through the water outlet 11. After the ice cubes melt into water, they can flow into the collecting tube 12 through the water outlet 11 for collection.

[0046] Embodiment 2

[0047] like Figure 1-Figure 10 As shown, this embodiment is improved on the basis of the first embodiment as follows: Further, as Figure 4 and Figure 5 As shown, the bottom support net 13 is threadedly connected to the inner wall of the bottom docking ring 1;

[0048] like Figure 6 As shown, two grille plates 14 are symmetrically installed on the bottom support net 13, and an isolation portion 15 is formed between the two grille plates 14 and the bottom support net 13. The two grille plates 14 are slidably connected with the same baffle 16. In the experiment, when it is necessary to irritate the mouse, the baffle 16 is pulled upward and the mouse to be detected is driven into the isolation portion 15 at the same time, and then the baffle 16 is lowered to limit the mouse to be detected, and the mouse is clamped by the tail using tools such as hemostatic forceps to irritate the mouse.

[0049] Embodiment 3

[0050] like Figure 1-Figure 10As shown, this embodiment is improved on the basis of the first embodiment as follows: Further, as Figure 1 , Fig. 9 and Fig.10 As shown, a light-proof bag 21 is provided on the side wall of the top cover 4. The top of the bag 21 is fixedly connected to the top cover 4, and a constriction portion 22 is provided on the bottom.

[0051] Further, such as Figure 1 and Figure 2 As shown, a limit rod 23 is circumferentially arranged on the top of the air duct 5 .

[0052] During the day, when it is necessary to simulate the night environment, the tie mouth 22 is opened and pulled downward by hand, and the tie mouth 22 is pulled to the bottom of the limit rod 23, and the tie mouth 22 is loosened. At this time, the tie mouth 22 will be tightened and clamped at the bottom of the limit rod 23, and then the net cage 2 will be fully wrapped by the bag 21 to block the external light, thereby simulating a dark environment.

[0053] like Figure 8 As shown, a lighting lamp 24 is installed at the bottom of the top cover 4. At night, when it is necessary to simulate the daytime environment, the lighting lamp 24 can be turned on to illuminate the interior of the net cage 2 for simulation.

[0054] Embodiment 4

[0055] like Figure 1-Figure 10 As shown, this embodiment is improved on the basis of the first embodiment as follows: Further, as Figure 8 As shown, a speaker 25 is installed at the bottom of the top cover 4. When it is necessary to scare and stimulate the mouse, the speaker 25 can emit noise into the inside of the cage 2 to stimulate the mouse.

[0056] Workflow:

[0057] The mouse is placed in the mesh cage 2 through the opening 26 .

[0058] In order to detect whether mice like heat or not, the outside wind can be heated by the fan 7 and the hot air can be sent to the air duct 5 through the air duct pipe 8, and then the hot air is sent out through the air outlet 6 to increase the temperature inside the net cage 2. When it is necessary to lower the temperature inside the net cage 2, ice cubes are placed in the storage tube 9 and the heating function of the fan 7 is turned off. When the air passes through the storage tube 9, the ice cubes can absorb the heat in the air, so that the temperature of the air after passing through the storage tube 9 is reduced, thereby achieving cooling of the inside of the net cage 2.

[0059] When it is necessary to irritate the mouse, the baffle 16 is pulled upwards, and the detected mouse is driven into the isolation part 15, and then the baffle 16 is lowered to limit the detected mouse, and the mouse is clamped by the tail using tools such as hemostats to irritate the mouse.

[0060] During the day, when it is necessary to simulate the night environment, the tie mouth 22 is opened and pulled downward by hand, and the tie mouth 22 is pulled to the bottom of the limit rod 23, and the tie mouth 22 is loosened. At this time, the tie mouth 22 will be tightened and clamped on the bottom of the limit rod 23, and then the net cage 2 is fully wrapped by the bag 21 to block the external light, thereby completing the simulation; at night, when it is necessary to simulate the daytime environment, the lighting 24 is turned on to illuminate the interior of the net cage 2 for simulation.

[0061] When it is necessary to shock and stimulate the mouse, the speaker 25 can emit noise into the inside of the cage 2 to stimulate the mouse.

[0062] By stimulating mice in multiple aspects, the autonomic nervous system and enteric nervous system of the gastrointestinal tract are affected, thereby directly or indirectly affecting the release of gastrointestinal hormones to regulate the sensory and motor functions of the gastrointestinal tract.

[0063] However, as is well known to those skilled in the art, the working principles and wiring methods of the fan 7, lighting 24 and speaker 25 are commonplace and are conventional means or common knowledge, and will not be elaborated here. Those skilled in the art may make any optional selections according to their needs or convenience.

[0064] The above different embodiments can be combined, replaced and used in conjunction with each other.

[0065] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0066] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for establishing a Mongolian medicine syndrome animal model, characterized in that: The bottom docking ring (1) comprises a bottom docking ring (1), the bottom docking ring (1) is provided with an air delivery structure, the top of the bottom docking ring (1) is fixedly connected to a mesh cage (2), the inner wall of the bottom docking ring (1) is provided with a bottom support net (13), and the bottom of the bottom docking ring (1) is detachably clamped with a feces collection frame (3); A top cover (4) is fixedly mounted on the top of the mesh cage (2).

2. The device for establishing the Mongolian medicine syndrome animal model according to claim 1, characterized in that: The bottom docking ring (1) is provided with an air duct (5), the bottom of the mesh cage (2) is fixedly connected to the top of the air duct (5), and an air outlet hole (6) communicating with the inner cavity of the air duct (5) is provided on the inner wall of the bottom docking ring (1); The air delivery structure comprises a fan (7) and an air duct pipe (8), wherein the air outlet of the air duct pipe (8) is connected to the inner cavity of the air duct (5), and the air inlet of the air duct pipe (8) is connected to the air outlet end of the fan (7).

3. The device for establishing the Mongolian medicine syndrome animal model according to claim 2, characterized in that: A funnel-shaped storage tube (9) is connected to the tube wall of the air duct tube (8); the top of the storage tube (9) is open and is clamped with a sealing cover (10); a water outlet hole (11) is provided at the bottom of the storage tube (9); a collecting tube (12) is threadedly connected to the bottom of the storage tube (9); and the collecting tube (12) is connected to the storage tube (9) via the water outlet hole (11).

4. The device for establishing the Mongolian medicine syndrome animal model according to claim 1, characterized in that: The bottom support net (13) is threadedly connected to the inner wall of the bottom docking ring (1); Two grid plates (14) are symmetrically mounted on the bottom support net (13), a separation portion (15) is formed between the two grid plates (14) and the bottom support net (13), and the two grid plates (14) are slidably connected to a common baffle (16).

5. The device for establishing the Mongolian medicine syndrome animal model according to claim 1, characterized in that: A slot (17) is provided on the inner wall of the bottom docking ring (1), a slider (18) is slidably connected to the slot (17), a clip strip (19) matching the slot (17) is provided on the inner wall of the feces collection frame (3), a clip joint (20) is provided on the top of the clip joint (19), and the clip joint (20) is clipped into the corresponding slot (17).

6. The device for establishing the Mongolian medicine syndrome animal model according to claim 2, characterized in that: The side wall of the top cover (4) is provided with a light-proof bag (21); the top of the bag (21) is fixedly connected to the top cover (4), and the bottom is provided with a tie opening (22).

7. The device for establishing the Mongolian medicine syndrome animal model according to claim 6, characterized in that: A limiting rod (23) is provided in a circular pattern on the top of the air duct (5).

8. The device for establishing the Mongolian medicine syndrome animal model according to claim 6, characterized in that: A lighting lamp (24) is installed at the bottom of the top cover (4).

9. The device for establishing the Mongolian medicine syndrome animal model according to claim 1, characterized in that: The net cage (2) is provided with an opening (26) for placing an animal.

10. The device for establishing the Mongolian medicine syndrome animal model according to claim 1, characterized in that: A speaker (25) is installed at the bottom of the top cover (4).

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