Reaction kettle for producing medical intermediates

Abstract

The utility model discloses a reaction kettle for producing medical intermediates, relates to the technical field of reaction kettles, and solves the problems that a stirring and mixing device is arranged at the bottom in the prior art, the stirring efficiency is lower, and a stirring device in the reaction kettle is easy to damage due to larger stirring resistance generated during liquid stirring, so that the production cost is reduced. The problem of drug retention easily occurs in the filling equipment of the reaction kettle during drug filling, so that the technical problems of drug failure, pollution and the like easily occur are solved; comprising a reaction kettle body, two supporting frames are arranged outside the reaction kettle body, a supporting transverse plate is fixedly connected between the two supporting frames, and a mixing rotating rod is rotationally sleeved with the reaction kettle body; according to the reaction kettle disclosed by the utility model, the stirring resistance is reduced, and meanwhile, medicines at the upper part of the reaction kettle body are fully mixed and stirred, so that the effect of accelerating the mixing of the medicines is achieved, and the medicines are prevented from being polluted due to long-time retention.

Description

Technical Field

[0001] The utility model relates to the technical field of reaction kettles, in particular to a reaction kettle used for the production of pharmaceutical intermediates. Background Art

[0002] A reactor is broadly understood as a container for physical or chemical reactions. The heating, evaporation, cooling and low-speed mixing functions required by the process are realized through the structural design and parameter configuration of the container. According to the "reactor" provided by the Chinese patent authorization announcement number CN209772122U, three sets of coils are installed, and a common coil system of steam and circulating cooling water is used to heat and cool the reactor. The steam and cooling circulating water inlets and outlets are each equipped with a high-temperature resistant valve partition, so the heating speed and cooling speed of the reactor are greatly improved, and the quality of the product is also improved. However, the reactor itself is large in size, and a stirring and mixing device is set at the bottom, and its stirring efficiency is relatively low. Secondly, due to the large stirring resistance generated when the liquid is stirred, the stirring device in the reactor is prone to damage, and when the drug is added, the filling equipment of the reactor is prone to drug retention, which is prone to drug failure and contamination.

[0003] Therefore, a reaction kettle for the production of pharmaceutical intermediates is designed to solve the above problems. Utility Model Content

[0004] The utility model provides a reactor for the production of pharmaceutical intermediates, which solves the problem that a stirring and mixing device is arranged at the bottom, the stirring efficiency is relatively low, and secondly, since a large stirring resistance is generated when the liquid is stirred, the stirring device in the reactor is prone to damage, and when the drug is added, the filling equipment of the reactor is prone to drug retention, which leads to technical problems such as drug failure and pollution.

[0005] In order to solve the above technical problems, the utility model provides a reactor for the production of pharmaceutical intermediates, including a reactor body, two support frames are provided on the outside of the reactor body, a support cross plate is fixedly connected between the two support frames, a mixing rotating rod is rotatably sleeved inside the reactor body, a plurality of first mixing plates are fixedly connected to the outside of the mixing rotating rod, a full mixing component is provided inside the reactor body, filling pipes are fixedly sleeved inside the two support frames, one end of the two filling pipes are connected to the reactor body, and a filling mediation component is provided inside the two filling pipes.

[0006] Preferably, a driving motor is fixedly installed at the bottom of the reaction kettle body, and the output end of the driving motor is fixedly connected to the bottom end of the mixing rotating rod.

[0007] Preferably, the fully mixing component includes a lifting turret, a transmission plate, a lifting sleeve, a limit plate, a lifting frame, a servo hydraulic cylinder and a second mixing plate, the outer part of the mixing turret is movably sleeved with the lifting turret, and a plurality of second mixing plates are fixedly connected to both sides of the lifting turret, the outer wall of the mixing turret is fixedly connected with a transmission plate, the transmission plate is slidably sleeved with the lifting turret, the outer wall of the lifting turret is fixedly sleeved with two limit plates, and a lifting sleeve is rotatably sleeved between the two limit plates, the internal sealing movably sleeved with the lifting frame of the reactor body, the bottom end of the lifting frame is fixedly sleeved with the lifting sleeve, the inner part of the supporting cross plate is fixedly sleeved with a servo hydraulic cylinder, and one end of the hydraulic support rod inside the servo hydraulic cylinder is fixedly sleeved with the lifting frame.

[0008] Preferably, two drain valves are fixedly sleeved on the bottom of the reactor body, and the two drain valves are symmetrically distributed with the axis of the reactor body as the center.

[0009] Preferably, the filling and mediation assembly includes a connecting pipe, a sealing baffle, a sealing ring sleeve, a connecting pipe, a through-hole groove, a sealing gasket, a sealing threaded barrel, an adjusting screw and a discharge valve. The two filling pipes are fixedly installed with a sealing baffle inside, the two sealing baffles are fixedly sleeved with a sealing ring sleeve inside, the two sealing ring sleeves are sealed and movably sleeved with a connecting pipe inside, the two connecting pipes are provided with a plurality of through-hole grooves inside, the two connecting pipes are fixedly sleeved with a sealing gasket outside, the two filling pipes are fixedly sleeved with a sealing threaded barrel inside, the two sealing threaded barrels are threadedly sleeved with an adjusting screw inside, one end of the two adjusting screws is fixedly connected to the corresponding connecting pipe, the top ends of the two filling pipes are fixedly sleeved with a connecting pipe, and the bottoms of the two filling pipes are fixedly connected with a discharge valve.

[0010] Preferably, the other ends of the two adjusting screws pass through the sealing threaded barrel and are fixedly connected with an adjusting handle.

[0011] Compared with the related art, the reactor for producing pharmaceutical intermediates provided by the utility model has the following beneficial effects:

[0012] The utility model provides a reactor for the production of pharmaceutical intermediates, wherein a mixing rotating rod is rotatably sleeved inside the reactor body, and a plurality of first mixing plates are arranged outside the mixing rotating rod, so that the medicine inside the reactor body is mixed, a lifting rotating frame is movably sleeved outside the mixing rotating rod, and a plurality of second mixing plates are fixedly installed on the outer wall of the lifting rotating frame, and a lifting sleeve is rotatably sleeved outside the lifting rotating frame, and a servo hydraulic cylinder is arranged on the top of the reactor body, so that the lifting frame outside the lifting sleeve is fixedly connected to the servo hydraulic cylinder, thereby adjusting the position of the second mixing plate, realizing sufficient mixing and stirring of the medicine on the upper part of the reactor body while reducing the stirring resistance, thereby accelerating the efficiency of the medicine mixing;

[0013] A filling pipe is fixedly installed inside the support frame, and a sealing partition is fixedly installed on the inner wall of the filling pipe, and the connecting pipe is sealed and sleeved inside the filling pipe through a sealing ring sleeve, and a plurality of through-hole grooves are opened on the outside of the connecting pipe, so that the filled medicine can reach the interior of the reactor body, and an adjusting screw is sealed and sleeved on the internal thread of the filling pipe to connect with the connecting pipe, and a discharge valve is fixedly connected to the bottom end of the filling pipe, so that the medicine retained in the filling pipe can be quickly discharged, and manual control of the medicine filling is realized, and the medicine feeding is stopped after the filling, and the retained medicine is discharged to prevent the medicine from being retained for a long time, which may cause the medicine to be contaminated. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the structure of the utility model;

[0015] Figure 2 It is a schematic diagram of the structure of the utility model in side section;

[0016] Figure 3 For this utility model Figure 2 The enlarged structural diagram at A in the middle;

[0017] Figure 4 For this utility model Figure 2 Schematic diagram of the enlarged structure at point B.

[0018] Numbers in the figure: 1. Reactor body; 2. Support frame; 3. Support cross plate; 4. Mixing rod; 5. First mixing plate; 6. Full mixing assembly; 601. Lifting and lowering frame; 602. Transmission plate; 603. Lifting sleeve; 604. Limiting plate; 605. Lifting frame; 606. Servo hydraulic cylinder; 607. Second mixing plate; 7. Driving motor; 8. Drain valve; 9. Filling and regulating assembly; 901. Connecting pipe; 902. Sealing partition; 903. Sealing ring sleeve; 904. Connecting pipe; 905. Through-hole groove; 906. Sealing pad; 907. Sealing threaded barrel; 908. Adjusting screw; 909. Discharge valve; 10. Filling pipe; 11. Adjusting handle. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0020] like Figure 1-4 As shown, the reactor for the production of pharmaceutical intermediates described in the utility model includes a reactor body 1, two support frames 2 are provided on the outside of the reactor body 1, a support cross plate 3 is fixedly connected between the two support frames 2, a mixing rotating rod 4 is rotatably sleeved inside the reactor body 1, and a plurality of first mixing plates 5 are fixedly connected to the outside of the mixing rotating rod 4, a full mixing component 6 is provided inside the reactor body 1, filling pipes 10 are fixedly sleeved inside the two support frames 2, one end of the two filling pipes 10 are connected to the reactor body 1, and a filling mediation component 9 is provided inside the two filling pipes 10.

[0021] A driving motor 7 is fixedly installed at the bottom of the reactor body 1, and the output end of the driving motor 7 is fixedly connected to the bottom end of the mixing rotating rod 4, thereby driving the first mixing plate 5 outside the mixing rotating rod 4 to rotate, so that the drugs are mixed and stirred.

[0022] The fully mixing assembly 6 includes a lifting rotating frame 601, a transmission plate 602, a lifting sleeve frame 603, a limit plate 604, a lifting frame 605, a servo hydraulic cylinder 606 and a second mixing plate 607. The outer part of the mixing rotating rod 4 is movably sleeved with the lifting rotating frame 601, and a plurality of second mixing plates 607 are fixedly connected on both sides of the lifting rotating frame 601. The outer wall of the mixing rotating rod 4 is fixedly connected with the transmission plate 602, and the transmission plate 602 is slidably sleeved with the lifting rotating frame 601. The outer wall of the lifting rotating frame 601 is fixedly connected with the transmission plate 602. There are two limit plates 604 sleeved, and a lifting sleeve frame 603 is rotatably sleeved between the two limit plates 604. The internal sealing of the reactor body 1 is movably sleeved with a lifting frame 605, and the bottom end of the lifting frame 605 is fixedly sleeved with the lifting sleeve frame 603. The inside of the supporting cross plate 3 is fixedly sleeved with a servo hydraulic cylinder 606, and one end of the hydraulic support rod inside the servo hydraulic cylinder 606 is fixedly sleeved with the lifting frame 605; thereby, the drugs on the upper part of the reactor body 1 can be mixed and stirred, thereby accelerating the efficiency of drug mixing.

[0023] Two drain valves 8 are fixedly sleeved on the bottom of the reactor body 1. The two drain valves 8 are symmetrically distributed around the axis of the reactor body 1, so as to discharge the mixed drugs.

[0024] The filling mediation assembly 9 includes a connecting pipe 901, a sealing baffle 902, a sealing ring sleeve 903, a connecting pipe 904, a through hole groove 905, a sealing gasket 906, a sealing threaded cylinder 907, an adjusting screw 908 and a discharge valve 909. The sealing baffles 902 are fixedly installed inside the two filling pipes 10, the sealing ring sleeves 903 are fixedly sleeved inside the two sealing baffles 902, the connecting pipes 904 are sealed and movably sleeved inside the two sealing ring sleeves 903, the two connecting pipes 904 are provided with a plurality of through hole grooves 905, and the outsides of the two connecting pipes 904 are fixed. A sealing gasket 906 is sleeved, and a sealing threaded tube 907 is fixedly sleeved inside the two filling tubes 10. Adjusting screws 908 are threadedly sleeved inside the two sealing threaded tubes 907. One end of the two adjusting screws 908 is fixedly connected to the corresponding connecting tube 904. A connecting tube 901 is fixedly sleeved on the top of the two filling tubes 10, and a discharge valve 909 is fixedly connected to the bottom of the two filling tubes 10, so that the filling of the drug can be manually controlled, and the drug injection is stopped after the filling, and the retained medicine is discharged to prevent the drug from being retained for a long time and causing drug contamination.

[0025] The other ends of the two adjusting screws 908 both pass through the sealing threaded tube 907 and are fixedly connected with the adjusting handle 11, thereby facilitating the adjusting screws 908 to rotate.

[0026] Working principle:

[0027] The first step: a mixing rotating rod 4 is rotated and sleeved inside the reaction kettle body 1, and a plurality of first mixing plates 5 are fixedly installed outside the mixing rotating rod 4. Then, a driving motor 7 is fixedly installed at the bottom of the reaction kettle body 1 and is fixedly connected to the mixing rotating rod 4, so that the drugs inside the reaction kettle body 1 are mixed;

[0028] Step 2: A lifting frame 601 is movably sleeved on the outside of the mixing rod 4, and a plurality of second mixing plates 607 are fixedly installed on the outer wall of the lifting frame 601, and the transmission plate 602 on the outside of the mixing rod 4 is slidably sleeved with the lifting frame 601, so that the mixing rod 4 rotates and drives the lifting frame 601 to rotate;

[0029] Step 3: A lifting frame 603 is rotatably sleeved on the outside of the lifting rotating frame 601, and a servo hydraulic cylinder 606 is provided on the top of the reactor body 1, so that the lifting frame 605 outside the lifting frame 603 is fixedly connected to the servo hydraulic cylinder 606, thereby adjusting the position of the second mixing plate 607, achieving sufficient mixing and stirring of the drugs on the upper part of the reactor body 1 while reducing the stirring resistance, thereby accelerating the efficiency of drug mixing;

[0030] The operation method of injecting the medicine through the filling pipe 10 is as follows:

[0031] In the first step, a filling pipe 10 is fixedly installed inside the support frame 3 so that one end of the filling pipe 10 is connected to the reactor body 1;

[0032] Step 2: A sealing baffle 902 is fixedly installed on the inner wall of the filling pipe 10, and a connecting pipe 904 is movably connected thereto through a sealing ring sleeve 903. A plurality of through-hole grooves 905 are provided on the outside of the connecting pipe 904, so that the drug enters the interior of the reactor 1 through the through-hole grooves 905;

[0033] Step 3: An adjusting screw 908 is connected to the connecting pipe 904 through the sealing thread sleeve inside the filling pipe 10. By adjusting the position of the through hole groove 905, when the through hole groove 905 is on the right side of the sealing ring sleeve 903, the filling drug enters the connecting pipe 904 through the through hole groove 905 and enters the inside of the reactor body 1. On the contrary, when the through hole groove 905 is moved to the left side of the sealing ring sleeve 903, the drug stops entering the inside of the reactor 1 through the through hole groove 905. By adjusting the time for the connecting pipe 904 to move to the right, the drug filling amount can be quickly adjusted.

[0034] Step 4: A discharge valve 909 is fixedly connected to the bottom end of the filling pipe 10 so that the medicine retained in the filling pipe 10 can be quickly discharged, and the filling of the medicine can be manually controlled. After the filling, the medicine is stopped, and the retained medicine is discharged to prevent the medicine from being retained for a long time, which may cause drug contamination.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A reactor for producing pharmaceutical intermediates, comprising a reactor body (1), characterized in that: Two support frames (2) are provided on the outside of the reactor body (1), a support cross plate (3) is fixedly connected between the two support frames (2), a mixing rotating rod (4) is rotatably sleeved inside the reactor body (1), a plurality of first mixing plates (5) are fixedly connected to the outside of the mixing rotating rod (4), a full mixing component (6) is provided inside the reactor body (1), a filling pipe (10) is fixedly sleeved inside the two support frames (2), one end of the two filling pipes (10) is connected to the reactor body (1), and a filling mediation component (9) is provided inside the two filling pipes (10).

2. A reactor for the production of pharmaceutical intermediates according to claim 1, characterized in that: A driving motor (7) is fixedly mounted on the bottom of the reaction kettle body (1), and an output end of the driving motor (7) is fixedly connected to the bottom end of the mixing rotating rod (4).

3. A reactor for producing pharmaceutical intermediates according to claim 1, characterized in that: The fully mixing component (6) comprises a lifting rotating frame (601), a transmission plate (602), a lifting sleeve frame (603), a limit plate (604), a lifting frame (605), a servo hydraulic cylinder (606) and a second mixing plate (607); the outer part of the mixing rotating rod (4) is movably sleeved with the lifting rotating frame (601); both sides of the lifting rotating frame (601) are fixedly connected to a plurality of second mixing plates (607); the outer wall of the mixing rotating rod (4) is fixedly connected to the transmission plate (602); the transmission plate (602) and the lifting rotating frame (607) are fixedly connected to each other. 601) is slidably sleeved, the outer wall of the lifting rotating frame (601) is fixedly sleeved with two limit plates (604), and a lifting sleeve frame (603) is rotatably sleeved between the two limit plates (604), the internal sealing movably sleeved with a lifting frame (605), the bottom end of the lifting frame (605) is fixedly sleeved with the lifting sleeve frame (603), the interior of the supporting cross plate (3) is fixedly sleeved with a servo hydraulic cylinder (606), and one end of the internal hydraulic support rod of the servo hydraulic cylinder (606) is fixedly sleeved with the lifting frame (605).

4. The reactor for producing pharmaceutical intermediates according to claim 1, characterized in that: Two drain valves (8) are fixedly sleeved on the bottom of the reaction kettle body (1), and the two drain valves (8) are symmetrically distributed with the axis of the reaction kettle body (1) as the center.

5. The reactor for producing pharmaceutical intermediates according to claim 1, characterized in that: The filling and mediation assembly (9) comprises a connecting pipe (901), a sealing baffle (902), a sealing ring sleeve (903), a connecting pipe (904), a through hole groove (905), a sealing gasket (906), a sealing threaded cylinder (907), an adjusting screw (908) and a discharge valve (909). The two filling pipes (10) are both fixedly installed with a sealing baffle (902), the two sealing baffles (902) are both fixedly sleeved with a sealing ring sleeve (903), the two sealing ring sleeves (903) are both sealed and movably sleeved with a connecting pipe (904), and the two connecting pipes (904) are both fixedly sleeved with a sealing baffle (902). ) are provided with a plurality of through-hole grooves (905) inside, the outsides of the two connecting pipes (904) are fixedly sleeved with sealing gaskets (906), the insides of the two filling pipes (10) are fixedly sleeved with sealing threaded tubes (907), the insides of the two sealing threaded tubes (907) are threadedly sleeved with adjusting screws (908), one end of the two adjusting screws (908) is fixedly connected to the corresponding connecting pipe (904), the top ends of the two filling pipes (10) are fixedly sleeved with connecting pipes (901), and the bottoms of the two filling pipes (10) are fixedly connected with discharge valves (909).

6. A reaction kettle for the production of pharmaceutical intermediates according to claim 5, characterized in that: The other ends of the two adjusting screws (908) both pass through the sealing threaded cylinder (907) and are fixedly connected with an adjusting handle (11).

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