Novel cell kit for gene editing
By designing a new kit structure, including placing plates, semicircular tanks, cover plates and rectangular boxes, the problem of difficult fixing of the reagent bottles during use is solved, and the stability of the reagent bottles and the convenience of waste liquid collection is achieved.
Patent Information
- Application Number
- CN202421637038.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-11
- Publication Date
- 2025-04-15
- Estimated Expiration
- 2034-07-11
AI Technical Summary
The existing cell kits for gene editing are difficult to fix the reagent bottles when used, resulting in easy movement or pouring when subjected to external forces, increasing the workload of the operator.
A new type of reagent kit is designed, including a placing plate, a semicircular tank, a cover plate and a rectangular box. Through the design of the semicircular tank and a reinforcement tank, the reagent bottle can be effectively fixed; the water inlet hole and pull-out block structure of the rectangular box are convenient for collecting and temporarily storing test waste liquid.
This kit not only facilitates personnel to clamp and fix the reagent bottle during operation, improves the stability of the reagent bottle, but also facilitates the collection and temporary storage of a small amount of test waste liquid, reducing the workload of the operator.
Smart Images
Figure CN222757051U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a novel cell kit for gene editing, and in particular to a novel cell kit for gene editing applied in the field of kits. Background Art
[0002] A box used to hold chemical reagents for detecting chemical components, drug residues, virus types, etc. is called a test kit. A gene-edited cell kit is a type of test kit, which is a tool for performing gene editing at the cellular level.
[0003] When using an existing cell test kit for gene editing, after taking out the reagent bottle inside and placing it directly on a platform, it is easier to move and tip over when subjected to external force. When using other clamping tools to fix the reagent bottle, personnel need to prepare the clamping tools in advance, which will increase the workload of personnel. Therefore, the existing test kit brings certain inconvenience to personnel when in use. Utility Model Content
[0004] In view of the above-mentioned prior art, the technical problem to be solved by the present invention is that it is difficult to fix the reagent bottle when the existing cell kit for gene editing is in use.
[0005] In order to solve the above problems, the utility model provides a novel cell kit for gene editing, including a kit, a placement plate is movably inserted inside the kit, a semicircular groove one is opened at the side end of the placement plate, a reagent bottle is movably inserted inside the semicircular groove one, a cover plate is placed on the side end of the kit, a semicircular groove two is opened at one end of the cover plate close to the placement plate and is movably inserted with the reagent bottle, a rectangular box is slidably inserted inside the placement plate, a water inlet hole and a plurality of reinforcement grooves are opened at the side end of the rectangular box, and the water inlet hole is communicated with the rectangular box.
[0006] In the above-mentioned new type of cell test kit for gene editing, it is not only convenient for personnel to clamp and fix the reagent bottle during operation, but also convenient for personnel to collect and temporarily store a small amount of test waste liquid.
[0007] As a further improvement of the present application, the diameter of the reinforcement groove is equal to the outer diameter of the reagent bottle, and in the initial state, the end of the cover plate away from the placement plate is in close contact with the inner wall of the reagent box.
[0008] As a further improvement of the present application, a rectangular groove is provided at the side end of the rectangular box, and a pull-out block is fixedly connected to the inner wall of the rectangular groove.
[0009] As a further improvement of the present application, a pair of side ends of the rectangular box are coated with a magnetic coating 1, and a pair of inner side walls of the placement plate are coated with a magnetic coating 2.
[0010] As a further improvement of the present application, observation slots are provided at both the upper and lower ends of the rectangular box, and a transparent block is fixedly connected to the inside of the observation slot.
[0011] As another improvement of the present application, a pair of support grooves are opened at the side ends of the rectangular box, the internal threads of the support grooves are connected to support blocks, and the side ends of the support blocks are fixedly connected to rubber blocks.
[0012] In summary, the test kit is not only convenient for personnel to clamp and fix the reagent bottle during operation, with an ideal clamping effect, but also convenient for personnel to collect and temporarily store a small amount of test waste liquid. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a schematic diagram of the overall structure of the first and second implementation modes of the present application;
[0014] Figure 2 This is a schematic diagram of the placement plate structure of the first embodiment of the present application;
[0015] Figure 3 This is a schematic diagram of the cover plate structure of the first embodiment of the present application;
[0016] Figure 4 This is a schematic diagram of a rectangular box structure according to the first embodiment of the present application;
[0017] Figure 5 This is a schematic diagram of the structure of a pull-out block according to the first embodiment of the present application;
[0018] Figure 6 This is a schematic diagram of the water inlet hole and the support block structure of the first embodiment and the second embodiment of the present application.
[0019] Description of the numbers in the figure:
[0020] 1. Reagent box; 2. Placement plate; 3. Semicircular groove 1; 4. Reagent bottle; 5. Cover plate; 6. Semicircular groove 2; 7. Rectangular box; 8. Water inlet hole; 9. Rectangular groove; 10. Pull-out block; 11. Magnetic coating 1; 12. Magnetic coating 2; 13. Transparent block; 14. Support groove; 15. Support block; 16. Rubber block; 17. Reinforcement groove. DETAILED DESCRIPTION
[0021] Two implementation modes of the present application are described in detail below with reference to the accompanying drawings.
[0022] The first implementation method:
[0023] Figure 1-6A novel cell kit for gene editing is shown, including a kit 1, which is a simple, reliable and rapid T7EI-based kit 1 for detecting mutations in genomic DNA after gene editing, and mainly utilizes the characteristics of T7EI that can recognize and enzyme-cut incompletely paired DNA double strands. A placement plate 2 is movably inserted inside the kit 1, and a semicircular groove 3 is provided at the side end of the placement plate 2. A reagent bottle 4 is movably inserted inside the semicircular groove 3. A cover plate 5 is placed on the side end of the kit 1, and the reagent bottle 4 is protected by the cover plate 5 and the placement plate 2 to prevent it from being crushed by foreign objects. A semicircular groove 6 movably inserted with the reagent bottle 4 is provided at one end of the cover plate 5 close to the placement plate 2, and a rectangular box 7 is slidably inserted inside the placement plate 2, and a water inlet hole 8 and a plurality of reinforcement grooves 17 are provided at the side end of the rectangular box 7, and the water inlet hole 8 is communicated with the rectangular box 7;
[0024] The diameter of the reinforcement groove 17 is equal to the outer diameter of the reagent bottle 4. In the initial state, the end of the cover plate 5 away from the placement plate 2 is in close contact with the inner wall of the reagent box 1. A rectangular groove 9 is opened at the side end of the rectangular box 7, and a pull-out block 10 is fixedly connected to the inner wall of the rectangular groove 9. A pair of side ends of the rectangular box 7 are coated with a magnetic coating 11, and a pair of inner side walls of the placement plate 2 are coated with a magnetic coating 2 12. Observation grooves are opened at the upper and lower ends of the rectangular box 7, and a transparent block 13 is fixedly connected to the inside of the observation groove.
[0025] When in use, the placement plate 2 is manually pulled out from the reagent kit 1, and then the cover plate 5 is removed from the placement plate 2, and the reagent bottle 4 is taken out from the semicircular groove 3, and the pull-out block 10 is manually pulled to drive the rectangular box 7 to move to the outside of the placement plate 2. After moving to a suitable position, the rectangular box 7 is moved by Figure 4 Move the vertical state to Figure 6 The lower end of the reagent bottle 4 is then inserted into the reinforcement groove 17 (combined with Figure 6 As shown), the reagent bottle 4 is installed and fixed on the rectangular box 7, so that the personnel can place and clamp the reagent bottle 7 during the test, so that it is not easy to overturn when subjected to external force. During use, a certain amount of test waste liquid can be poured into the water inlet 8, and the rectangular box 7 is used to temporarily store a small amount of waste liquid. Therefore, the test kit is not only convenient for personnel to clamp and fix the reagent bottle 4 during operation, but also convenient for personnel to collect and temporarily store a small amount of test waste liquid.
[0026] The second implementation method:
[0027] Based on the first embodiment, this embodiment adds structures such as a support block 15, and the rest of the parts are consistent with the first embodiment.
[0028] Figure 6It is shown that a pair of support grooves 14 are opened at the side ends of the rectangular box 7 , and a support block 15 is connected to the inner thread of the support groove 14 , and a rubber block 16 is fixedly connected to the side end of the support block 15 .
[0029] When the rectangular box 7 is pulled out from the placement plate 2 and placed on the platform for use, the support block 15 is rotated to drive the rubber block 16 to move downward until the lower end of the rubber block 16 presses the lower end of the platform, so that the rubber block 16 is adsorbed on the platform. The rubber block 16 can increase the friction force on the rectangular box 7, thereby improving the stability of the rectangular box 7, making it difficult to move, and then improving the stability of the reagent bottle 4.
[0030] In view of current practical needs, the protection scope of the above-mentioned implementation mode adopted in this application is not limited to this. Various changes made within the knowledge scope of technical personnel in this field without departing from the concept of this application still fall within the protection scope of this utility model.
Claims
1. A novel cell kit for gene editing, comprising a kit (1), characterized in that: A placement plate (2) is movably inserted inside the reagent box (1), a semicircular groove (3) is provided at the side end of the placement plate (2), a reagent bottle (4) is movably inserted inside the semicircular groove (3), a cover plate (5) is placed on the side end of the reagent box (1), a semicircular groove (6) is provided at one end of the cover plate (5) close to the placement plate (2) and is movably inserted with the reagent bottle (4), a rectangular box (7) is slidably inserted inside the placement plate (2), a water inlet hole (8) and a plurality of reinforcement grooves (17) are provided at the side end of the rectangular box (7), and the water inlet hole (8) is communicated with the rectangular box (7).
2. A novel cell kit for gene editing according to claim 1, characterized in that: The diameter of the reinforcement groove (17) is equal to the outer diameter of the reagent bottle (4). In the initial state, the end of the cover plate (5) away from the placement plate (2) is in close contact with the inner wall of the reagent box (1).
3. A novel cell kit for gene editing according to claim 2, characterized in that: A rectangular groove (9) is provided at the side end of the rectangular box (7), and a drawer block (10) is fixedly connected to the inner wall of the rectangular groove (9).
4. A novel cell kit for gene editing according to claim 3, characterized in that: A pair of side ends of the rectangular box (7) are coated with a magnetic coating 1 (11), and a pair of inner side walls of the placement plate (2) are coated with a magnetic coating 2 (12).
5. A novel cell kit for gene editing according to claim 4, characterized in that: The upper and lower ends of the rectangular box (7) are both provided with observation slots, and a transparent block (13) is fixedly connected inside the observation slot.
6. A novel cell kit for gene editing according to claim 5, characterized in that: A pair of support grooves (14) are provided at the side ends of the rectangular box (7), the inner threads of the support grooves (14) are connected to support blocks (15), and the side ends of the support blocks (15) are fixedly connected to rubber blocks (16).