Human collagen preparation and fermentation device

Abstract

The utility model relates to the technical field of collagen fermentation, and particularly discloses a human collagen preparation and fermentation device which comprises a containing mechanism, the containing mechanism comprises a fermentation tank and a feeding bin arranged on the fermentation tank, a stirring assembly is arranged on the upper surface of the fermentation tank, and a heating device and a monitoring mechanism are arranged on the lower surface of the fermentation tank. The monitoring mechanism comprises a second annular plate fixedly arranged on the peripheral side face of the fermentation tank, a PH monitoring instrument and a ventilation pipe opening, an electric valve is arranged on the ventilation pipe opening, a temperature monitoring instrument and a dissolved oxygen instrument are fixedly installed on the second annular plate, and a plurality of conduction pipes are connected to the dissolved oxygen instrument; according to the device, various parameters such as the temperature, the PH value and the dissolved oxygen content are monitored in real time by arranging the dissolved oxygen instrument, the temperature monitoring instrument and the PH monitoring instrument, so that an optimal fermentation environment is formed in the tank, human collagen with high biological activity can be prepared conveniently, and the application requirements in the fields of medicines, biological materials and the like can be met.

Description

Technical Field

[0001] The utility model belongs to the technical field of collagen fermentation, and specifically relates to a human collagen preparation and fermentation device. Background Art

[0002] Human collagen is based on the original gene sequence of collagen in human skin. The parts with strong water solubility and high biological activity are selected for optimization and splicing and reorganization to obtain a new recombinant human collagen sequence. The bio-fermentation technology can be used to achieve large-scale production. Experiments have confirmed that this collagen has good water solubility and high biological activity. Its performance is better than that of natural collagen. It has broad application prospects in the fields of biomedical materials, beauty cosmetics, food and health care. During the processing, a fermentation device is required for microbial fermentation to prepare human collagen with high biological activity.

[0003] Existing fermentation equipment lacks the function of real-time monitoring and adjustment of the temperature, pH, dissolved oxygen content and pH value in the fermentation tank, and thus cannot provide the best fermentation environment for microorganisms, affecting the effect of human collagen preparation.

[0004] To this end, those skilled in the art have proposed a fermentation device for preparing human collagen to solve the problems raised by the background technology.

[0005] The above information disclosed in the background technology is only used to increase the understanding of the background technology of the utility model, therefore, it may include prior art that is not known to ordinary technicians in this field. Utility Model Content

[0006] The purpose of the utility model is to provide a human collagen preparation fermentation device to solve the problems raised in the above background technology.

[0007] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0008] A human collagen preparation and fermentation device, comprising:

[0009] A containing mechanism, the containing mechanism comprising a fermentation tank and a feeding bin arranged on the fermentation tank, the fermentation tank comprises an inner bin inside, the inner bin is connected with the feeding bin, a stirring assembly is arranged on the upper surface of the fermentation tank, and a heating device is arranged on the lower surface of the fermentation tank;

[0010] The monitoring mechanism includes a second ring plate fixedly arranged on the side surface of the fermentation tank, a pH monitoring instrument and a ventilation pipe port, an electric valve is arranged on the ventilation pipe port, and the ventilation pipe port is connected with the interior of the inner warehouse. A temperature monitoring instrument and a dissolved oxygen meter are fixedly installed on the second ring plate, and a plurality of conduction pipes are connected to the dissolved oxygen meter, and the conduction pipes are connected with the interior of the inner warehouse.

[0011] Preferably, the stirring assembly comprises a driving motor fixedly mounted on the upper surface of the fermentation tank, and a rotating shaft is connected to the output end of the driving motor.

[0012] Preferably, the rotating shaft is located in the inner bin, a plurality of movable stirring rods are fixedly mounted on the peripheral side of the rotating shaft, and fixed stirring rods are arranged on the peripheral side inside the inner bin.

[0013] Preferably, a first ring plate is fixedly mounted on the peripheral side of the fermentation tank, and a plurality of brackets are arranged on the first ring plate.

[0014] Preferably, a mounting seat is fixedly mounted on the second ring plate, a mounting groove is formed on the upper surface of the mounting seat, the number of the mounting grooves is two, and an acid solution tank and an alkaline solution tank are respectively placed in the two mounting grooves.

[0015] Preferably, the acidic solution tank and the alkaline solution tank are both provided with a pump and a transmission pipe, one end of the transmission pipe is connected to the pump, and the other end of the transmission pipe is connected to the fermentation tank.

[0016] Compared with the prior art, the beneficial effects of the utility model are:

[0017] (1) The utility model provides a dissolved oxygen meter, a temperature monitoring meter and a pH monitoring meter to respectively monitor the dissolved oxygen content, the fermentation environment temperature and the pH value of the solution in the fermentation tank in real time, and provides an acid solution tank and an alkaline solution tank around the fermentation tank. According to the data of the pH monitoring meter, the corresponding pump is started to neutralize the reactants in the tank. According to the dissolved oxygen data measured by the dissolved oxygen meter, the electric valve can be opened for ventilation. At the same time, the fluidity of the solution can be increased by increasing the speed of the driving motor, thereby increasing the dissolved oxygen content of the reaction solution. According to the temperature in the tank displayed by the temperature monitoring meter, the interior is heated by a heating device, thereby ensuring that the interior always maintains the optimal fermentation temperature. Therefore, the fermentation environment in the fermentation tank can be monitored in real time, and multiple parameters such as temperature, pH value, dissolved oxygen content, etc. can be controlled in real time to form an optimal fermentation environment in the tank, which is convenient for preparing human collagen with high biological activity and can meet the application needs in the fields of medicine and biomaterials.

[0018] The above summary is for the purpose of description only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the utility model will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a left-side stereoscopic structural schematic diagram of the utility model;

[0020] Figure 2 This is a schematic diagram of the internal structure of the fermentation tank of the utility model;

[0021] Figure 3 It is a right-side stereoscopic structural schematic diagram of the utility model;

[0022] Figure 4 It is a top view of the utility model.

[0023] In the figure: 1. fermentation tank; 2. drive motor; 3. pH monitoring instrument; 4. transmission pipe; 5. pump; 6. installation groove; 7. acid solution tank; 8. alkaline solution tank; 9. mounting seat; 10. heating equipment; 11. bracket; 12. first ring plate; 13. temperature monitoring instrument; 14. second ring plate; 15. electric valve; 16. ventilation pipe; 17. feed silo; 18. rotating shaft; 19. movable stirring rod; 20. fixed stirring rod; 21. inner bin; 22. dissolved oxygen meter; 23. transmission pipe. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] Embodiment 1:

[0026] See also Figure 1-Figure 4 As shown, a human collagen preparation fermentation device comprises:

[0027] The containing mechanism comprises a fermentation tank 1 and a feeding bin 17 arranged on the fermentation tank 1. The fermentation tank 1 comprises an inner bin 21, which is connected to the feeding bin 17. A stirring assembly is arranged on the upper surface of the fermentation tank 1, and a heating device 10 is arranged on the lower surface of the fermentation tank 1.

[0028] The monitoring mechanism includes a second ring plate 14 fixedly arranged on the side of the fermentation tank 1, a pH monitoring instrument 3 and a ventilation pipe port 16, an electric valve 15 is arranged on the ventilation pipe port 16, and the ventilation pipe port 16 is connected to the interior of the inner warehouse 21. A temperature monitoring instrument 13 and a dissolved oxygen meter 22 are fixedly installed on the second ring plate 14, and a plurality of conduction pipes 23 are connected to the dissolved oxygen meter 22, and the conduction pipes 23 are connected to the interior of the inner warehouse 21.

[0029] Specifically, the stirring assembly includes a driving motor 2 fixedly mounted on the upper surface of the fermentation tank 1 , and a rotating shaft 18 is connected to the output end of the driving motor 2 .

[0030] Specifically, the rotating shaft 18 is located in the inner bin 21 , a plurality of movable stirring rods 19 are fixedly installed on the circumferential side of the rotating shaft 18 , and a fixed stirring rod 20 is arranged on the circumferential side of the inner bin 21 .

[0031] Specifically, a first ring plate 12 is fixedly installed on the side of the fermentation tank 1, and a plurality of brackets 11 are arranged on the first ring plate 12.

[0032] Specifically, a mounting seat 9 is fixedly mounted on the second ring plate 14 , and a mounting groove 6 is formed on the upper surface of the mounting seat 9 . There are two mounting grooves 6 , and an acid solution tank 7 and an alkaline solution tank 8 are placed in the two mounting grooves 6 , respectively.

[0033] Specifically, the acid solution tank 7 and the alkaline solution tank 8 are both provided with a pump 5 and a transmission pipe 4 , one end of the transmission pipe 4 is connected to the pump 5 , and the other end of the transmission pipe 4 is connected to the fermentation tank 1 .

[0034] As can be seen from the above, the present device monitors the dissolved oxygen content, fermentation environment temperature and solution pH value in the fermentation tank 1 in real time by setting a dissolved oxygen meter 22, a temperature monitoring meter 13 and a pH monitoring meter 3, and sets an acid solution tank 7 and an alkaline solution tank 8 around the fermentation tank 1. According to the data of the pH monitoring meter 3, the corresponding pump 5 is started to neutralize the reactants in the tank. According to the dissolved oxygen data measured by the dissolved oxygen meter 22, the electric valve 15 can be opened for ventilation. At the same time, the fluidity of the solution is increased by increasing the speed of the driving motor 2, thereby increasing the dissolved oxygen content of the reaction solution. According to the temperature in the tank displayed by the temperature monitoring instrument 13, the interior is heated by the heating device 10, thereby ensuring that the interior always maintains the optimal fermentation temperature. Therefore, the fermentation environment in the fermentation tank 1 can be monitored in real time, and various parameters such as temperature, pH value, dissolved oxygen content, etc. can be controlled in real time to form an optimal fermentation environment in the tank, so as to facilitate the preparation of human collagen with high biological activity, which can meet the application needs in the fields of medicine and biomaterials.

[0035] The standard parts used in this utility model can be purchased from the market, and the special-shaped parts can be customized according to the description and the drawings. The specific connection methods of each part adopt the conventional means such as mature bolts, rivets, welding, etc. in the prior art. The machinery, parts and equipment all adopt the conventional models in the prior art, and the circuit connection adopts the conventional connection method in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.

[0036] In the description of the present utility model, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. The meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0037] In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0038] In the present utility model, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0039] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

[0040] In the drawings of the embodiments disclosed by the present invention, only the structures related to the embodiments disclosed by the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other.

[0041] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A fermentation device for preparing human collagen, characterized in that: include: A containing mechanism, the containing mechanism comprising a fermentation tank (1) and a feed bin (17) arranged on the fermentation tank (1), the fermentation tank (1) comprising an inner bin (21) inside, the inner bin (21) being connected to the feed bin (17), a stirring assembly being arranged on the upper surface of the fermentation tank (1), and a heating device (10) being arranged on the lower surface of the fermentation tank (1); A monitoring mechanism, the monitoring mechanism comprising a second ring plate (14) fixedly arranged on the side surface of the fermentation tank (1), a pH monitoring instrument (3) and a ventilation pipe opening (16), the ventilation pipe opening (16) being provided with an electric valve (15), the ventilation pipe opening (16) being connected to the interior of an inner chamber (21), a temperature monitoring instrument (13) and a dissolved oxygen meter (22) being fixedly mounted on the second ring plate (14), the dissolved oxygen meter (22) being connected to a plurality of conduction pipes (23), the conduction pipes (23) being connected to the interior of the inner chamber (21).

2. A human collagen preparation and fermentation device according to claim 1, characterized in that: The stirring assembly comprises a driving motor (2) fixedly mounted on the upper surface of the fermentation tank (1), and a rotating shaft (18) is connected to the output end of the driving motor (2).

3. A human collagen preparation and fermentation device according to claim 2, characterized in that: The rotating shaft (18) is located in the inner bin (21), a plurality of movable stirring rods (19) are fixedly mounted on the peripheral side of the rotating shaft (18), and a fixed stirring rod (20) is arranged on the inner peripheral side of the inner bin (21).

4. The human collagen preparation and fermentation device according to claim 1, characterized in that: A first ring plate (12) is fixedly mounted on the peripheral side of the fermentation tank (1), and a plurality of brackets (11) are arranged on the first ring plate (12).

5. The human collagen preparation and fermentation device according to claim 1, characterized in that: A mounting seat (9) is fixedly mounted on the second ring plate (14), and a mounting groove (6) is provided on the upper surface of the mounting seat (9). The number of the mounting grooves (6) is two, and an acid solution tank (7) and an alkaline solution tank (8) are respectively placed in the two mounting grooves (6).

6. A human collagen preparation and fermentation device according to claim 5, characterized in that: The acidic solution tank (7) and the alkaline solution tank (8) are both provided with a pump (5) and a transmission pipe (4); one end of the transmission pipe (4) is connected to the pump (5), and the other end of the transmission pipe (4) is connected to the fermentation tank (1).

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