Mixing device for preparing gamma-aminobutyric acid particles

By setting up a hollow mixing rack, air pump and exhaust pore structure in the mixing device, the problem of adhesion of γ-aminobutyric acid particles is solved by using airflow shock and heating pipes, and convenient cleaning and efficient production are achieved.

CN222766241UActive Publication Date: 2025-04-18ZHENGZHOU WEIYI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421564903.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-07-03
Publication Date
2025-04-18
Estimated Expiration
2034-07-03

AI Technical Summary

Technical Problem

In the prior art, γ-aminobutyric acid particles tend to adhere to the inner side wall of the mixing granulator and the stirring device during the preparation process, resulting in difficulty in cleaning.

Method used

A mixing device is designed, including a hollow mixing rack, an air pump and an exhaust pore structure, which disengages the adhesion particles through airflow impact, combines a one-way plate and a spring to prevent clogging, and is dried by heating pipes to reduce adhesion and facilitate cleaning.

Benefits of technology

It effectively reduces cleaning work, improves production efficiency, reduces cleaning difficulty, and ensures the cleanliness of the device and product quality.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a mixing device for preparing gamma-aminobutyric acid particles, which comprises a pharmaceutical bin, a support frame arranged at the bottom of the pharmaceutical bin, a stirring frame rotatably mounted at the bottom of the pharmaceutical bin, a particle separating blade rotatably mounted on the side wall of the pharmaceutical bin, a plurality of feed ports arranged at the top of the pharmaceutical bin, and a discharge port arranged at the bottom of the side wall of the pharmaceutical bin, the upper end of the pneumatic sliding ring is fixedly connected to the stirring frame, the stirring frame is of a hollow structure, the gas output end of the pneumatic sliding ring is connected with the stirring frame, the stirring frame is provided with a first exhaust hole and a second exhaust hole, the gas input end of the pneumatic sliding ring is connected with a gas pump, and a one-way valve is arranged at the top of the pharmacy bin. After granulation is completed, the air pump is started to blow the position where particles are easily adhered, so that the adhered particles are impacted by air flow, then are separated from adhesion and are discharged from the discharge port, and the cleaning work is conveniently reduced.
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Description

Technical Field

[0001] The utility model belongs to the technical field of mixing granulators and relates to a mixing device for preparing gamma-aminobutyric acid particles. Background Art

[0002] GABA granules are a type of granular drug formed by mixing GABA with other ingredients. When making GABA granules, GABA and other ingredients need to be mixed first, then a binder is added to bind the GABA and other ingredients, and finally the granules are formed under stirring in a mixing granulator.

[0003] Due to the effect of the adhesive, after the formed particles are discharged from the mixing granulator, some particles adhere to the inner wall and the stirring device of the mixing granulator, which needs to be disassembled for cleaning, which is troublesome. Utility Model Content

[0004] In view of the above problems, the utility model proposes a mixing device for preparing γ-aminobutyric acid particles, which well solves the problems in the prior art.

[0005] In order to achieve the above purpose, the technical solution adopted by the utility model is as follows:

[0006] A mixing device for preparing gamma-aminobutyric acid particles, comprising:

[0007] A pharmaceutical warehouse, wherein a support frame is provided at the bottom of the pharmaceutical warehouse;

[0008] A stirring frame, the stirring frame is rotatably mounted on the bottom of the pharmaceutical warehouse, the stirring frame comprises a central axis portion, and a plurality of stirring plates are arranged in a circular array outside the central axis portion;

[0009] A particle-classifying blade, the particle-classifying blade being rotatably mounted on the side wall of the medicine-making bin;

[0010] A stirring drive and a particle-classifying drive, wherein the stirring drive and the particle-classifying drive are both fixedly connected to the support frame, and the output ends of the stirring drive and the particle-classifying drive are respectively fixedly connected to the stirring frame and the particle-classifying blade;

[0011] A feed inlet and a discharge inlet, wherein a plurality of feed inlets are arranged at the top of the pharmaceutical warehouse, and the discharge inlet is arranged at the bottom of the side wall of the pharmaceutical warehouse;

[0012] A pneumatic slip ring, wherein the lower end of the pneumatic slip ring is fixedly mounted on the support frame, the upper end of the pneumatic slip ring is fixedly connected to the stirring frame, the stirring frame is a hollow structure, and the gas output end of the pneumatic slip ring is connected to the stirring frame;

[0013] A first exhaust hole, the exhaust hole is provided at the upper portion of the stirring plate close to one end of the side wall of the pharmaceutical warehouse;

[0014] A second exhaust hole, wherein a plurality of the second exhaust holes are provided, the second exhaust holes are opened on the side wall of the middle axis portion, and the airflow of the second exhaust holes is in contact with the side wall of the stirring plate;

[0015] An air pump, wherein an output end of the air pump is connected to a gas input end of the pneumatic slip ring;

[0016] A one-way valve is fixedly installed on the top of the pharmaceutical warehouse.

[0017] Optionally, both the first exhaust hole and the second exhaust hole are installed with a one-way plate, and one end of the one-way plate close to the stirring frame is fixedly connected to a tension spring, and the tension spring is fixedly connected to the stirring frame.

[0018] Optionally, one end of the one-way plate close to the stirring frame is conical.

[0019] Optionally, the stirring plate is provided with an inclined surface, and the first exhaust hole is provided on the inclined surface, and the first exhaust hole faces the side wall of the pharmaceutical warehouse.

[0020] Optionally, a water inlet is provided at the upper end of the medicine storage bin, and the water inlet is connected to a cleaning water source.

[0021] Optionally, a heating tube is connected to the output end of the air pump.

[0022] Optionally, the air pump output end is connected to a gas filter box.

[0023] Compared with the prior art, the utility model has the following beneficial effects:

[0024] 1. By setting a hollow stirring frame, an air pump, a first exhaust hole and a second exhaust hole, after the granulation is completed, the air pump is turned on to blow the position where the particles are prone to adhesion, so that the adhered particles are impacted by the air flow and then separated from the discharge port, which is convenient for reducing the cleaning work;

[0025] 2. By setting a one-way plate and a tension spring, the first exhaust hole and the second exhaust hole form a one-way opening structure, thereby reducing the possibility of drug powder and particles entering the first exhaust hole and the second exhaust hole and causing blockage during the granulation process;

[0026] 3. The first exhaust hole and the second exhaust hole are made to spray hot air through the heating tube, which is convenient for drying the particles during spraying and reducing adhesion, and is also convenient for heating and drying the pharmaceutical warehouse after cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the utility model;

[0028] Figure 2It is a structural schematic diagram of the position of the pneumatic slip ring of an embodiment of the utility model;

[0029] Figure 3 It is a schematic structural diagram of the stirring frame part of an embodiment of the utility model.

[0030] Reference numerals: 1, pharmaceutical warehouse; 11, support frame; 12, feed inlet; 13, discharge outlet; 14, water inlet;

[0031] 21. stirring frame; 211. middle axis; 212. stirring plate; 22. stirring drive;

[0032] 31. Grain separation blade; 32. Grain separation drive;

[0033] 41. Pneumatic slip ring; 421. First exhaust hole; 422. Second exhaust hole; 43. Air pump; 431. Heating tube; 432. Gas filter box; 44. One-way valve; 451. One-way plate; 452. Tension spring. DETAILED DESCRIPTION

[0034] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0035] See also Figure 1 and Figure 2, a mixing device for preparing γ-aminobutyric acid particles disclosed in an embodiment of the utility model, includes a pharmaceutical warehouse 1, a support frame 11 is arranged at the bottom of the pharmaceutical warehouse 1, a stirring frame 21 is rotatably installed at the bottom of the pharmaceutical warehouse 1, the stirring frame 21 includes a central axis 211, and a plurality of stirring plates 212 are arranged in a circular array outside the central axis 211, a particle separation blade 31 is rotatably installed on the side wall of the pharmaceutical warehouse 1, the stirring frame 21 and the particle separation blade 31 are respectively connected to a stirring drive 22 and a particle separation drive 32, and the stirring drive 22 and the particle separation drive 32 are both fixedly connected to the support frame 11, a plurality of feeding ports 12 are arranged on the top of the pharmaceutical warehouse 1, and a plurality of feeding ports 12 are arranged on the bottom of the side wall of the pharmaceutical warehouse 1 A discharge port 13 is provided, and a pneumatic slip ring 41 is fixedly installed at the output end of the stirring drive 22. The lower end of the pneumatic slip ring 41 is fixedly installed on the support frame 11, and the upper end of the pneumatic slip ring 41 is fixedly connected to the stirring frame 21. The stirring frame 21 is a hollow structure. The gas output end of the pneumatic slip ring 41 is connected to the stirring frame 21. The upper part of the stirring plate 212 close to one end of the side wall of the pharmaceutical warehouse 1 is provided with a first exhaust hole 421, and the side wall of the central axis 211 is provided with a plurality of second exhaust holes 422. The airflow of the second exhaust hole 422 is in contact with the side wall of the stirring plate 212. The gas input end of the pneumatic slip ring 41 is connected to an air pump 43, and a one-way valve 44 is provided on the top of the pharmaceutical warehouse 1.

[0036] Specifically, the stirring frame 21 is partially set to a hollow state, and the air pump 43 is connected to the stirring frame 21, and a first exhaust hole 421 and a second exhaust hole 422 are opened at appropriate positions of the stirring frame 21, so that the first exhaust hole 421 and the second exhaust hole 422 hit the side wall of the pharmaceutical warehouse 1 and the side wall of the stirring frame 21 respectively.

[0037] In this way, by setting up the hollow stirring frame 21, the air pump 43 and the first exhaust hole 421 and the second exhaust hole 422, after the granulation is completed, the air pump 43 is turned on to blow the positions where the particles are prone to sticking, so that the stuck particles are impacted by the airflow and then separated from the sticking and discharged from the discharge port 13, which is convenient for reducing the cleaning work.

[0038] In some feasible ways, the pharmaceutical warehouse 1 is cylindrical, the support frame 11 is arranged at the bottom of the pharmaceutical warehouse 1, the middle axis 211 is a hollow circular tube, the stirring plate 212 is a hollow rectangular tube, the bottom of the middle axis 211 is closed and fixedly connected to the pneumatic slip ring 41, the pneumatic slip ring 41 is fixedly installed on the support frame 11, the pneumatic slip ring 41 connects the air pump 43 and the stirring frame 21, so that the air pump 43 supplies air to the rotating stirring frame 21, the pneumatic slip ring 41 is an air slip ring, which is a prior art and will not be repeated here, the middle axis 211 is fixedly connected with a driving gear set, and the input end of the driving gear set is connected to the stirring drive 22. The particle blade 31 is provided with a blade portion, and the rotation produces a cutting effect, which is convenient for forming smaller particles. The particle drive 32 is a driving motor that drives the particle blade 31 to rotate. The particle blade 31 part is a prior art and will not be repeated. A plurality of feed ports 12 are used for feeding γ-aminobutyric acid and other components and adhesives, respectively, and the discharge port 13 is used for discharging after granulation is completed. When cleaning is performed after granulation is completed, the air pump 43 sprays through the first exhaust hole 421 and the second exhaust hole 422, and a one-way valve 44 is provided to facilitate the exhaust of gas.

[0039] As a specific embodiment of a mixing device for preparing γ-aminobutyric acid particles provided in the application, please refer to Figure 2 and Figure 3 The first exhaust hole 421 and the second exhaust hole 422 are both installed with a one-way plate 451 , and one end of the one-way plate 451 close to the stirring frame 21 is fixedly connected to a tension spring 452 , and the tension spring 452 is fixedly connected to the stirring frame 21 .

[0040] In general, by providing the one-way plate 451 and the tension spring 452, the first exhaust hole 421 and the second exhaust hole 422 form a one-way opening structure, thereby reducing the possibility of drug powder and particles entering the first exhaust hole 421 and the second exhaust hole 422 and causing blockage during the granulation process.

[0041] Furthermore, one end of the one-way plate 451 close to the stirring frame 21 is conical.

[0042] It should be understood that during cleaning, the gas lifts up the one-way plate 451 through pressure for blowing. After the blowing is completed, the tension spring 452 pulls the one-way plate 451 to reset and re-closes the first exhaust hole 421 and / or the second exhaust hole 422. By setting the end of the one-way plate 451 close to the stirring frame 21 to be conical, it is convenient for the one-way plate 451 to enter the first exhaust hole 421 or the second exhaust hole 422.

[0043] Furthermore, the stirring plate 212 is provided with an inclined surface, and the first exhaust hole 421 is provided on the inclined surface, and the first exhaust hole 421 faces the side wall of the pharmaceutical warehouse 1 .

[0044] In some feasible embodiments, the end of the one-way plate 451 located on the outside of the stirring plate 212 is in the shape of a circular plate, and the end located on the inside of the stirring plate 212 is in the shape of a cone. To facilitate the installation of the tension spring 452, mounting openings are provided on one side of the stirring plate 212 and on the top of the middle axis 211. The mounting openings are covered with mounting plates fixed with bolts, and the mounting plates are sealed and connected to the stirring plate 212 or the middle axis 211.

[0045] It should be understood that by providing the inclined surface, the first exhaust hole 421 is directed toward the side wall of the pharmaceutical warehouse 1 , thereby making it easier for the airflow to clean the particles on the side wall of the pharmaceutical warehouse 1 .

[0046] As another specific embodiment of a mixing device for preparing γ-aminobutyric acid particles provided by the application, please refer to Figure 1 A water inlet 14 is provided at the upper end of the pharmaceutical warehouse 1, and the water inlet 14 is connected to a cleaning water source.

[0047] In combination with specific usage scenarios, after granulation is completed, the pharmaceutical warehouse 1 needs to be cleaned. By setting a water inlet 14 to access a clean water source, the pharmaceutical warehouse 1 can be cleaned through the stirring frame 21.

[0048] For further information, see Figure 2 The output end of the air pump 43 is connected to a heating tube 431 .

[0049] It should be understood that the heating tube 431 is used to spray hot air from the first exhaust hole 421 and the second exhaust hole 422. On the one hand, it is convenient to dry the particles during spraying and reduce adhesion. On the other hand, it is convenient to heat and dry the pharmaceutical warehouse 1 after cleaning.

[0050] In some feasible embodiments, the heating tube 431 includes an outer tube, a spiral heating resistance wire is disposed inside the outer tube, and a gas pipeline is disposed inside the spiral heating resistance wire.

[0051] As a specific embodiment of a mixing device for preparing γ-aminobutyric acid particles provided in the application, the output end of the air pump 43 is connected to a gas filter box 432 .

[0052] It should be understood that by providing the gas filter box 432, the gas input by the air pump 43 is filtered, thereby reducing the contact between the medicine and dust in the air and improving the product quality.

[0053] In some feasible embodiments, the gas filter box 432 may be selected as a common air dust filtering device.

[0054] Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art may still modify the technical solutions described in the aforementioned embodiments, or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection scope of the present invention.

Claims

1. A mixing device for preparing γ-aminobutyric acid particles, characterized in that: include: A pharmaceutical warehouse, wherein a support frame is provided at the bottom of the pharmaceutical warehouse; A stirring frame, the stirring frame is rotatably mounted on the bottom of the pharmaceutical warehouse, the stirring frame comprises a central axis portion, and a plurality of stirring plates are arranged in a circular array outside the central axis portion; A particle-classifying blade, the particle-classifying blade being rotatably mounted on the side wall of the medicine-making bin; A stirring drive and a particle-classifying drive, wherein the stirring drive and the particle-classifying drive are both fixedly connected to the support frame, and the output ends of the stirring drive and the particle-classifying drive are respectively fixedly connected to the stirring frame and the particle-classifying blade; A feed inlet and a discharge inlet, wherein a plurality of feed inlets are arranged at the top of the pharmaceutical warehouse, and the discharge inlet is arranged at the bottom of the side wall of the pharmaceutical warehouse; A pneumatic slip ring, wherein the lower end of the pneumatic slip ring is fixedly mounted on the support frame, the upper end of the pneumatic slip ring is fixedly connected to the stirring frame, the stirring frame is a hollow structure, and the gas output end of the pneumatic slip ring is connected to the stirring frame; A first exhaust hole, the exhaust hole is provided at the upper portion of the stirring plate close to one end of the side wall of the pharmaceutical warehouse; A second exhaust hole, wherein a plurality of the second exhaust holes are provided, the second exhaust holes are opened on the side wall of the middle axis portion, and the airflow of the second exhaust holes is in contact with the side wall of the stirring plate; An air pump, wherein an output end of the air pump is connected to a gas input end of the pneumatic slip ring; A one-way valve is fixedly installed on the top of the pharmaceutical warehouse.

2. A mixing device for preparing γ-aminobutyric acid particles according to claim 1, characterized in that: The first exhaust hole and the second exhaust hole are both equipped with a one-way plate, and one end of the one-way plate close to the stirring frame is fixedly connected to a tension spring, and the tension spring is fixedly connected to the stirring frame.

3. A mixing device for preparing γ-aminobutyric acid particles according to claim 2, characterized in that: One end of the one-way plate close to the stirring frame is conical.

4. A mixing device for preparing γ-aminobutyric acid particles according to claim 3, characterized in that: The stirring plate is provided with an inclined surface, and the first exhaust hole is provided on the inclined surface, and the first exhaust hole faces the side wall of the pharmaceutical warehouse.

5. A mixing device for preparing γ-aminobutyric acid particles according to claim 1, characterized in that: A water inlet is provided at the upper end of the pharmaceutical warehouse, and the water inlet is connected to a cleaning water source.

6. A mixing device for preparing γ-aminobutyric acid particles according to claim 5, characterized in that: The air pump output end is connected with a heating tube.

7. A mixing device for preparing γ-aminobutyric acid particles according to any one of claims 1 to 6, characterized in that: The air pump output end is connected with a gas filter box.