Liquid nitrogen fumigation device for cryopreservation of semen sample

Abstract

The utility model discloses a liquid nitrogen fumigating device for cryopreservation of seminal fluid samples, which relates to the technical field of cryopreservation of seminal fluid samples and comprises a box body, a plurality of groups of brackets are uniformly fixed at two ends in the box body, a fumigating module is placed between every two groups of brackets, and a sample placing module is placed at the top of each group of fumigating module. The brackets with different heights are arranged in the box body, the fumigating pieces can be placed on the tops of the brackets, so that the appropriate distance of liquid nitrogen fumigating can be adjusted, the sample frame is separated through the multiple sets of partition plates, and then semen samples are effectively prevented from being scattered and stacked in the box body for freezing operation; therefore, the cryopreservation tubes can be quickly placed one by one according to the serial numbers during warehousing, the operation standardization of freezing and warehousing of semen samples is improved, and the overall quality of frozen sperms is effectively improved.

Description

Technical Field

[0001] The utility model relates to the technical field of semen sample freezing and storage, in particular to a liquid nitrogen fumigation device for semen sample freezing and storage. Background Art

[0002] In male fertility preservation, the method of semen freezing is related to the quality of semen after freezing, the success rate of pregnancy during assisted reproduction later, and the results of early embryonic development. The main methods of sperm preservation technology currently used are slow freezing, vitrification freezing and rapid freezing (liquid nitrogen vapor freezing method). Slow freezing needs to consider the ice crystal damage produced, and the results of sperm motility and DNA integrity after recovery are poor. Vitrification freezing is currently a popular freezing method for research.

[0003] In the prior art, a liquid nitrogen fumigation device is often used to quickly freeze semen samples. However, all the cryotubes in the existing fumigation freezing device are often directly put into liquid nitrogen after fumigation, which makes it impossible to quickly place the cryotubes one by one according to the numbers when they are put into storage, and this process may affect the quality of sperm after freezing. Utility Model Content

[0004] Based on this, the purpose of the utility model is to provide a liquid nitrogen fumigation device for cryopreservation of semen samples, so as to solve the technical problem in the prior art that all cryopreservation tubes are often directly put into liquid nitrogen after fumigation, resulting in the inability to quickly place the cryopreservation tubes one by one according to their numbers when they are put into storage.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a liquid nitrogen fumigation device for freezing semen samples, comprising a box body, a plurality of brackets are evenly fixed at both ends of the box body, a fumigation module is placed between each two groups of brackets, and a sample placement module is placed on the top of each group of fumigation modules;

[0006] The fumigation module includes a fumigation sheet, and the two ends of the bottom of the fumigation sheet are mounted on the top of the two sets of brackets. The fumigation module also includes a fumigation hole, and the fumigation hole and the through hole are connected to each other;

[0007] The sample placement module includes a sample rack, through holes, partitions and a sliding cover. The bottom of the sample rack is evenly provided with multiple groups of through holes, the inside of the sample rack is evenly fixed with multiple groups of partitions, the top of the sample rack is slidably connected with a sliding cover, and the sample placement module also includes a slide groove and a handle, and the slide groove cooperates with the sliding cover;

[0008] A box cover matched with the box body is arranged on the top of the box body, and a heat insulation cavity is provided inside the box body and the box cover.

[0009] By adopting the above technical solution, by arranging brackets of different heights inside the box, a fumigation sheet can be placed on the top of the bracket, so that the appropriate distance of liquid nitrogen fumigation can be adjusted, and the sample racks are separated by multiple groups of partitions, thereby effectively avoiding the semen samples from being scattered and piled up inside the box for freezing operations, so that the cryopreservation tubes can be quickly placed one by one according to the numbers when entering the warehouse, effectively improving the overall quality of the sperm after freezing.

[0010] The utility model is further configured that a plurality of groups of fumigation modules arranged in parallel are placed inside the box, and connecting plates are fixedly connected to both sides of the plurality of groups of fumigation modules.

[0011] By adopting the above technical solution, two groups of connecting plates connect multiple groups of fumigation sheets distributed in an upper and lower structure to each other, so that they form a whole, which can be directly placed inside the box for fumigation and freezing operations.

[0012] The utility model is further configured that the handle is connected to one end of the sample rack, and the handle and the sample rack are movably connected.

[0013] By adopting the above technical solution, the handle is convenient for tweezers to grasp, and the sample rack can be moved by tweezers to immerse in and remove from liquid nitrogen.

[0014] The utility model is further configured that handles are fixed at both ends of the box body, and rubber rings are fixed on the outer sides of the handles.

[0015] By adopting the above technical solution, there are welded handles on both sides of the outer side of the box body, which can be held by hand, making it convenient to carry the box body.

[0016] In summary, the utility model mainly has the following beneficial effects: the utility model arranges brackets of different heights inside the box, wherein a fumigation sheet can be placed on the top of the bracket, thereby being able to adjust the appropriate distance of liquid nitrogen fumigation, and the sample racks are separated by multiple groups of partitions, thereby effectively avoiding the semen samples from being scattered and piled up inside the box for freezing operations, so that the cryopreservation tubes can be quickly placed one by one according to the numbers when entering the warehouse, thereby improving the operational standardization of semen sample freezing and storage, and effectively improving the overall quality of sperm after freezing; BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is an exploded schematic diagram of the first overall embodiment of the utility model;

[0018] Figure 2 It is a cutaway view of the first embodiment of the utility model;

[0019] Figure 3 This is an enlarged view of the internal structure of the first embodiment of the utility model;

[0020] Figure 4 For this utility model Figure 3 A magnified image of point A;

[0021] Figure 5 This is a schematic diagram of the structure of the second embodiment of the present utility model.

[0022] In the figure: 1. box body; 2. bracket; 3. fumigation module; 301. fumigation sheet; 302. fumigation hole; 4. sample placement module; 401. sample rack; 402. through hole; 403. partition; 404. slide cover; 405. slide groove; 406. handle; 5. connecting plate; 6. box cover; 7. insulation cavity; 8. grip. DETAILED DESCRIPTION

[0023] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. The embodiments described below with reference to the drawings are exemplary and are only used to explain the utility model, and cannot be understood as limiting the utility model.

[0024] The following describes an embodiment of the utility model based on its overall structure.

[0025] Embodiment 1

[0026] The first embodiment of the present invention is as follows Figure 1-4 As shown, it includes a box body 1, and multiple groups of brackets 2 are evenly fixed at both ends of the box body 1, wherein the spacing between the brackets 2 is different to better adapt to actual usage conditions;

[0027] A fumigation module 3 is placed between each two groups of brackets 2. The fumigation module 3 includes a fumigation sheet 301. The fumigation sheet 301 is made of stainless steel and can support two groups of sample placement modules 4 at the same time. The bottom ends of the fumigation sheet 301 are mounted on the tops of the two groups of brackets 2.

[0028] The fumigation module 3 further includes a fumigation hole 302, and the fumigation hole 302 and the through hole 402 are interconnected. Specifically, the opening size of the fumigation hole 302 is smaller than the size of the sample rack 401, so that the fumigation hole 302 is aligned with the sample rack 401 to allow the steam to pass smoothly;

[0029] A sample placement module 4 is placed on the top of each group of fumigation modules 3. The sample placement module 4 includes a sample rack 401, a through hole 402, a partition 403 and a sliding cover 404. The sample rack 401 is also made of stainless steel.

[0030] A plurality of through holes 402 are evenly arranged at the bottom of the sample rack 401, wherein the through holes 402 ensure convection of liquid nitrogen vapor so that the semen sample is fully in contact with the liquid nitrogen vapor;

[0031] Multiple groups of partitions 403 are evenly fixed inside the sample rack 401, and the partitions 403 play the role of fixing the cryopreservation tubes;

[0032] The top of the sample rack 401 is slidably connected with a slide cover 404, and the sample placement module 4 also includes a slide groove 405, and the slide groove 405 cooperates with the slide cover 404. The slide cover 404 can prevent the cryopreservation tube from floating in the liquid nitrogen by moving and cooperating with the slide groove 405. When transferring, the slide cover 404 can be moved again to take out the restricted cryopreservation tube;

[0033] The sample placement module 4 further includes a handle 406, which is connected to one end of the sample rack 401, and the handle 406 and the sample rack 401 are movably connected, wherein the handle 406 is convenient for tweezers to grasp, and the sample rack 401 can be moved by tweezers to be immersed in and removed from liquid nitrogen;

[0034] As can be seen from the above, the independent sample rack 401 design separates the sample rack 401 from the device providing fumigation and freezing. The sample rack 401 can hold a semen sample alone, so the fumigation process and freezing process of each semen sample can be separated, avoiding the embarrassing situation that all samples can only be operated synchronously, and is suitable for a working environment where multiple samples are operated simultaneously;

[0035] The sample rack 401 adopts a sliding cover 404 to prevent the cryotube from leaving the sample rack 401 due to buoyancy, and the cryotube can be easily taken out by moving the sliding cover 404 during transfer;

[0036] The sample rack 401 adopts a method of opening holes at the bottom, which can allow steam to pass through and quickly cool the sample, and at the same time reduce buoyancy when immersed in liquid nitrogen, so that the sample rack 401 sinks to the bottom of the box 1. Through the sample rack 401, the cryopreservation tube can stay in the liquid nitrogen, and the freezing is more complete;

[0037] A matching box cover 6 is disposed on the top of the box body 1, and a heat insulation cavity 7 is provided inside the box body 1 and the box cover 6, wherein the heat insulation cavity 7 is filled with heat insulation material to ensure its temperature insulation effect;

[0038] Both ends of the box body 1 are fixed with handles 8, and rubber rings are fixed on the outside of the handles 8. The two sides of the outside of the box body 1 are respectively welded with handles 8, which can be held by hand, making it convenient to carry the box body 1.

[0039] Embodiment 2

[0040] The second embodiment of the present invention is as follows Figure 5 As shown, the main difference between the second embodiment of the utility model and the first embodiment is that the fumigation module 3 is fixedly connected by two groups of connecting plates 5, so that the multiple groups of fumigation sheets 301 are distributed in an upper and lower structure;

[0041] Multiple groups of fumigation modules 3 arranged in parallel are placed inside the box 1, and connecting plates 5 are fixedly connected to both sides of the multiple groups of fumigation modules 3, that is, two groups of connecting plates 5 connect multiple groups of fumigation sheets 301 distributed in an upper and lower structure to each other, so that they form a whole, which can be directly placed inside the box 1 for fumigation and freezing operations;

[0042] Furthermore, the distance between each group of fumigation modules 3 can be set to different distances according to actual requirements, so as to better adapt to actual usage conditions.

[0043] Although an embodiment of the utility model has been shown and described, this specific embodiment is merely an explanation of the utility model and is not a limitation of the utility model. The specific features, structures, materials or characteristics described may be combined in a suitable manner in any one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions and variations to the embodiments without creative contributions as needed without departing from the principles and purpose of the utility model. However, as long as they are within the scope of the claims of the utility model, they are protected by patent law.

Claims

1. A liquid nitrogen fumigation device for cryopreservation of semen samples, comprising a housing (1), characterized in that: A plurality of brackets (2) are evenly fixed at both ends of the box body (1), fumigation modules (3) are placed between the brackets (2), and a sample placement module (4) is placed on the top of each group of fumigation modules (3); The fumigation module (3) comprises a fumigation sheet (301), and the two ends of the bottom of the fumigation sheet (301) are mounted on the top of two groups of brackets (2). The sample placement module (4) comprises a sample rack (401), a through hole (402), a partition (403) and a sliding cover (404). The bottom of the sample rack (401) is evenly provided with a plurality of through holes (402), the inside of the sample rack (401) is evenly fixed with a plurality of partitions (403), and the top of the sample rack (401) is slidably connected with a sliding cover (404).

2. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 1, characterized in that: The fumigation module (3) further comprises a fumigation hole (302), and the fumigation hole (302) and the through hole (402) are interconnected.

3. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 1, characterized in that: The sample placement module (4) further comprises a slide groove (405) and a handle (406), and the slide groove (405) cooperates with the slide cover (404).

4. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 3, characterized in that: The handle (406) is connected to one end of the sample rack (401), and the handle (406) and the sample rack (401) are movably connected.

5. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 1, characterized in that: A plurality of groups of fumigation modules (3) arranged in parallel are placed inside the box (1), and connecting plates (5) are fixedly connected to both sides of the plurality of groups of fumigation modules (3).

6. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 1, characterized in that: The top of the box body (1) is provided with a box cover (6) that matches the box body (1), and a heat insulation cavity (7) is provided inside the box body (1) and the box cover (6).

7. The liquid nitrogen fumigation device for cryopreservation of semen samples according to claim 1, characterized in that: Handles (8) are fixed at both ends of the box body (1), and rubber rings are fixed on the outsides of the handles (8).

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