Centrifugal device for extracting bone marrow mesenchymal stem cells

By designing a centrifugal device for bone marrow mesenchymal stem cell extraction with ice box, fan and lifting system, the problem of cooling and easy access and placement of test tubes in the existing device is solved, and the extraction effect is improved.

CN222789469UActive Publication Date: 2025-04-25THE SECOND AFFILIATED HOSPITAL OF INNER MONGOLIA MEDICAL UNIV (INNER MONGOLIA ORTHOPEDIC RES INST)
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Patent Information

Application Number
CN202421460594.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-24
Publication Date
2025-04-25
Estimated Expiration
2034-06-24

AI Technical Summary

Technical Problem

The existing centrifugal device for bone marrow mesenchymal stem cell extraction is not convenient for the test tube to be picked up and placed, and at the same time, the test tube cooling function lacks the function, which causes the bone marrow fluid to deteriorate and affects the extraction effect.

Method used

A centrifugal device including an ice box, a fan and a lifting system is designed. The ice box is cooled and cooled by blowing cold air through a fan. The lifting system is made of a dual-axis motor and threaded rod structure to facilitate up and down movement of the test tube, achieving convenient access and placement of the test tube.

Benefits of technology

It effectively solves the problem of cooling and easy access to test tubes, avoiding the deterioration of bone marrow fluid due to high temperatures, and improving the extraction effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a centrifugal device for extracting mesenchymal stem cells, and relates to the technical field of mesenchymal stem cell analysis, the centrifugal device comprises a device body, a feed inlet and a lifting rod, the inner side of the device body is provided with a lifting plate, and the middle position above the lifting plate is provided with a driving motor; the output end of the driving motor is connected with a centrifugal box through a driving shaft, test tubes are installed above sponge pads, the outer walls of the two sides of the device body are provided with installation holes, ice boxes are installed on the inner sides of the installation holes, and fans are installed above the ice boxes. According to the test tube cooling device, ice blocks are placed in the ice box, then the ice box is installed in the installation hole, the draught fan works to blow air to the ice blocks in the ice box, formed cold air is exhausted through the multiple air outlet pipes, the cold air is exhausted into the device body, test tubes can be cooled conveniently, and the problem that the test tubes are inconvenient to cool is solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of bone marrow mesenchymal stem cell analysis, in particular to a centrifugal device for extracting bone marrow mesenchymal stem cells. Background Art

[0002] Bone marrow mesenchymal stem cells have the functions of self-replication, self-division, self-renewal, and multidirectional differentiation, and play an important role in the normal development and maturation of hematopoietic stem cells. Mesenchymal stem cells also have the ability to regulate the body's immune system. They can promote the recovery and normal function of the body's immune system by regulating the activity of immune cells and balancing immune responses. A centrifugal device is required during the extraction process, and the bone marrow fluid in the test tube is extracted into bone marrow mesenchymal stem cells through centrifugation. The current device is not convenient for taking and placing the test tube, causing inconvenience in use, and the device does not have the function of cooling the test tube, and high temperature is prone to cause the bone marrow fluid to deteriorate, thereby affecting the extraction effect. In view of this, in-depth research was conducted on the above-mentioned problems, and this case came into being. Utility Model Content

[0003] The utility model aims to provide a centrifugal device for extracting bone marrow mesenchymal stem cells, so as to solve the problem that the existing centrifugal device for extracting bone marrow mesenchymal stem cells mentioned in the background art does not have the function of cooling the test tubes and facilitating the taking and placing of the test tubes.

[0004] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a centrifugal device for extracting bone marrow mesenchymal stem cells, comprising a device body, a feed port and a lifting rod, a control panel is installed below the outer wall of one side of the device body, a cover body is threadedly installed on the top of the device body, a lifting plate is installed on the inner side of the device body, and a driving motor is installed at the middle position above the lifting plate, the output end of the driving motor is connected to a centrifugal box through a driving shaft, and sponge pads are evenly installed on the inner side of the centrifugal box, test tubes are installed above the sponge pads, mounting holes are provided on the outer walls of both sides of the device body, and ice boxes are installed on the inner sides of the mounting holes, fans are installed above the ice boxes, feed ports are provided at the tops of the ice boxes, and baffles are installed above the feed ports.

[0005] Preferably, the inner wall of the cover body is movably connected with a pressure plate via a rotating shaft, and the bottom end of the pressure plate is evenly provided with positioning grooves, and the inner walls of the positioning grooves are provided with protective pads.

[0006] Preferably, threaded rods are installed on both inner walls below the device body, and lifting rods are threadedly installed on the outer walls above the threaded rods, and the top ends of the lifting rods are fixedly connected to the lifting plate.

[0007] Preferably, a dual-axis motor is installed at the middle position of the inner wall below the device body, and both ends of the dual-axis motor are connected with first bevel teeth through a driving shaft, and second bevel teeth are installed on the outer wall below the threaded rod, and a meshing transmission structure is formed between the second bevel teeth and the first bevel teeth.

[0008] Preferably, limiting grooves are provided on both sides of the lifting rod, and the outer walls on both sides of the bottom end of the lifting rod are movably connected to the limiting grooves through limiting blocks.

[0009] Preferably, an air inlet pipe is arranged above the fan, and an air outlet pipe is evenly connected to an outer wall of one side of the ice box.

[0010] Preferably, a slide groove is provided above the ice box, and an outer wall of one side of the baffle is movably connected to the slide groove via a sliding block.

[0011] Compared with the prior art, the beneficial effects of the utility model are:

[0012] (1) The utility model provides an ice box, a fan and a device body. Ice cubes are placed in the ice box, and then the ice box is installed in the installation hole. The fan blows air toward the ice cubes in the ice box, and the resulting cold air is discharged through multiple air outlet pipes. The cold air is discharged into the device body, which is convenient for cooling the test tube, thereby solving the problem of inconvenience in cooling the test tube.

[0013] (2) The utility model provides a dual-axis motor, a threaded rod and a lifting rod. The dual-axis motor is used to rotate the first bevel gear, and the first bevel gear is meshed with the second bevel gear to rotate the threaded rod. The threaded rod cooperates with the thread of the lifting rod, so that the lifting rod can drive the lifting plate to move upward or downward, thereby allowing the centrifuge box to drive multiple test tubes to move upward or downward, making it easy to take and place the test tubes, thereby solving the problem of inconvenience in taking and placing the test tubes. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the cross-sectional structure of the device body of the utility model;

[0015] Figure 2 This is a schematic diagram of the structure of the ice box of the utility model from a top view;

[0016] Figure 3 This is a schematic diagram of the cross-sectional structure of the lifting rod of the utility model;

[0017] Figure 4 For this utility model Figure 1 Enlarged structural diagram at A in the middle.

[0018] In the figure: 1. control panel; 2. mounting hole; 3. centrifuge box; 4. pressure plate; 5. cover body; 6. test tube; 7. device body; 8. sponge pad; 9. ice box; 10. lifting plate; 11. threaded rod; 12. first bevel gear; 13. double-axis motor; 14. drive motor; 15. second bevel gear; 16. fan; 17. air outlet pipe; 18. baffle; 19. feed port; 20. slider; 21. slide groove; 22. lifting rod; 23. positioning groove. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] Example 1: Please refer to Figure 1-Figure 4 A centrifugal device for extracting bone marrow mesenchymal stem cells comprises a device body 7, a feed port 19 and a lifting rod 22, a control panel 1 is installed below the outer wall of one side of the device body 7, a cover body 5 is threadedly installed above the device body 7, a lifting plate 10 is installed inside the device body 7, and a driving motor 14 is installed at the middle position above the lifting plate 10, the output end of the driving motor 14 is connected to a centrifugal box 3 through a driving shaft, and a sponge pad 8 is evenly installed inside the centrifugal box 3, and a test tube 6 is installed above the sponge pad 8, mounting holes 2 are provided on the outer walls of both sides of the device body 7, and an ice box 9 is installed inside the mounting holes 2, a fan 16 is installed above the ice box 9, a feed port 19 is provided at the top of the ice box 9, and a baffle 18 is installed above the feed port 19;

[0021] The inner wall of the cover body 5 is movably connected to the pressing plate 4 through a rotating shaft, and the bottom end of the pressing plate 4 is evenly provided with positioning grooves 23, and the inner walls of the positioning grooves 23 are all provided with protective pads;

[0022] Threaded rods 11 are installed on both inner walls below the device body 7, and lifting rods 22 are threadedly installed on the outer walls above the threaded rods 11, and the tops of the lifting rods 22 are fixedly connected to the lifting plate 10;

[0023] A double-axis motor 13 is installed at the middle position of the inner wall below the device body 7, and both ends of the double-axis motor 13 are connected to the first bevel gear 12 through the driving shaft, and the outer wall below the threaded rod 11 is installed with a second bevel gear 15, and a meshing transmission structure is formed between the second bevel gear 15 and the first bevel gear 12;

[0024] Limiting grooves are provided on both sides of the lifting rod 22, and the outer walls on both sides of the bottom end of the lifting rod 22 are movably connected to the limiting grooves through limiting blocks;

[0025] Specifically, Figure 1 , Figure 3 and Figure 4 As shown, when this structure is used, the first bevel gear 12 is rotated by the operation of the dual-axis motor 13, and the first bevel gear 12 is meshed with the second bevel gear 15 to rotate the threaded rod 11, and the threaded cooperation between the threaded rod 11 and the lifting rod 22 enables the lifting rod 22 to drive the lifting plate 10 to move upward or downward, so that the centrifuge box 3 drives multiple test tubes 6 to move upward or downward, which is convenient for taking and placing the test tubes 6.

[0026] Embodiment 2: An air inlet pipe is provided above the fan 16, and an air outlet pipe 17 is evenly connected to the outer wall of one side of the ice box 9;

[0027] A slide groove 21 is provided above the ice box 9, and an outer wall of one side of the baffle 18 is movably connected to the slide groove 21 through a slider 20;

[0028] Specifically, Figure 1 and Figure 2 As shown, when this structure is used, ice cubes are placed in the ice box 9, and then the ice box 9 is installed in the installation hole 2. The fan 16 is operated to blow air toward the ice cubes in the ice box 9, and the resulting cold air is discharged through multiple air outlet pipes 17, and the cold air is discharged into the device body 7, so as to facilitate cooling of the test tube 6.

[0029] Working principle: When using the device, firstly, place the bone marrow mesenchymal stem cell test tube 6 on the sponge pad 8 in the centrifuge box 3, then cover the cover 5, so that the pressing plate 4 is pressed on the test tube 6 to fix it, and the centrifuge box 3 is rotated by driving the motor 14 to realize the centrifugal work of the test tube 6;

[0030] The first step to implement the innovation point:

[0031] The first bevel gear 12 is rotated by the operation of the dual-axis motor 13, and the first bevel gear 12 is meshed with the second bevel gear 15 to rotate the threaded rod 11. The threaded cooperation between the threaded rod 11 and the lifting rod 22 enables the lifting rod 22 to drive the lifting plate 10 to move upward or downward, so that the centrifuge box 3 drives multiple test tubes 6 to move upward or downward, which is convenient for taking and placing the test tubes 6.

[0032] The second innovation point implementation steps:

[0033] By putting ice cubes into the ice box 9, and then installing the ice box 9 into the installation hole 2, the fan 16 is operated to blow air towards the ice cubes in the ice box 9, and the formed cold air is discharged through multiple air outlet pipes 17, and the cold air is discharged into the device body 7 to cool down the multiple test tubes 6 to prevent deterioration.

[0034] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0035] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A centrifugal device for extracting bone marrow mesenchymal stem cells, comprising a device body (7), a feed port (19) and a lifting rod (22), characterized in that: A control panel (1) is installed below the outer wall of one side of the device body (7); a cover body (5) is threadedly installed above the device body (7); a lifting plate (10) is installed inside the device body (7); and a driving motor (14) is installed at a middle position above the lifting plate (10); the output end of the driving motor (14) is connected to a centrifugal box (3) through a driving shaft; and sponge pads (8) are evenly installed inside the centrifugal box (3); and test tubes (6) are installed above the sponge pads (8); mounting holes (2) are provided on the outer walls of both sides of the device body (7); and ice boxes (9) are installed inside the mounting holes (2); and fans (16) are installed above the ice boxes (9); and a feed port (19) is provided at the top of the ice box (9); and a baffle (18) is installed above the feed port (19).

2. A centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 1, characterized in that: The inner wall of the cover body (5) is movably connected to a pressure plate (4) via a rotating shaft, and positioning grooves (23) are evenly arranged at the bottom end of the pressure plate (4), and the inner walls of the positioning grooves (23) are all provided with protective pads.

3. The centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 1, characterized in that: Threaded rods (11) are installed on both inner walls below the device body (7), and lifting rods (22) are threadedly installed on the outer walls above the threaded rods (11), and the top ends of the lifting rods (22) are fixedly connected to the lifting plate (10).

4. A centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 3, characterized in that: A double-axis motor (13) is installed at the middle position of the inner wall below the device body (7), and both ends of the double-axis motor (13) are connected to the first bevel gear (12) through a driving shaft, and the outer wall below the threaded rod (11) is installed with a second bevel gear (15), and a meshing transmission structure is formed between the second bevel gear (15) and the first bevel gear (12).

5. The centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 1, characterized in that: Limiting grooves are arranged on both sides of the lifting rod (22), and the outer walls on both sides of the bottom end of the lifting rod (22) are movably connected to the limiting grooves through limiting blocks.

6. A centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 1, characterized in that: An air inlet pipe is arranged above the fan (16), and an air outlet pipe (17) is evenly connected to an outer wall of one side of the ice box (9).

7. The centrifugal device for extracting bone marrow mesenchymal stem cells according to claim 1, characterized in that: A slide groove (21) is provided above the ice box (9), and an outer wall of one side of the baffle (18) is movably connected to the slide groove (21) via a slider (20).

Citation Information

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