Special anti-pollution storage device for mRNA enzyme raw materials

By designing an mRNase raw material storage device including sealing and feeding parts, the problem of residual contamination of enzyme raw material after material removal in the prior art is solved, and higher practicality and safety are achieved.

CN222794042UActive Publication Date: 2025-04-25XINGSHI (SHANGHAI) BIOMEDICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421886614.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-06
Publication Date
2025-04-25
Estimated Expiration
2034-08-06

AI Technical Summary

Technical Problem

After the existing storage device takes the material, the residual enzyme raw material in the discharge tube will be contaminated by RNase enzyme in the air, causing deterioration and may contaminate the subsequently removed materials.

Method used

A storage device including a storage barrel, a extraction pump, a valve, a connecting pipe, a seal and a feed member is designed. The mutual cooperation between the seal and the connecting pipe ensures that the feed pipe can be taken off for disinfection after feeding, and the connecting pipe is protected from dust through the seal.

Benefits of technology

It effectively prevents enzyme raw materials from remaining in the pipe wall after the material is collected and contacts with air and impurities, avoids deterioration and pollution, and improves the practicality and safety of the storage device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of storage devices, and discloses a special anti-pollution storage device for mRNA (messenger ribonucleic acid) enzyme raw materials, which comprises a storage barrel, a transfer pump is mounted at the top of the storage barrel, a valve is mounted at the output end of the transfer pump, a connecting pipe is mounted at the upper end of the valve, and a sealing element is movably connected to the upper part of the connecting pipe. The upper portion of the connecting pipe is movably connected with a material conveying piece, the sealing piece comprises a connecting piece, the sealing piece further comprises a control sleeve, a sealing plug is arranged in the connecting piece and movably connected with the connecting pipe, the connecting piece comprises a top cover, the top cover is fixedly connected with the sealing plug, and the control sleeve is fixedly connected with the top cover. And the bottom surface of the top cover is fixedly connected with a connecting sleeve. According to the material conveying device, the sealing piece is matched with the connecting pipe, and the material conveying piece is matched with the connecting pipe, so that the material conveying pipe can be taken down to be disinfected after the device conveys materials, meanwhile, the connecting pipe can be subjected to dustproof protection through the sealing piece, and the material conveying device is more practical.
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Description

Technical Field

[0001] The utility model relates to the field of storage devices, in particular to a special anti-pollution storage device for mRNA enzyme raw materials. Background Art

[0002] mRNA enzymes, also known as RNA polymerases, are a class of enzymes that can transcribe DNA into mRNA. In cells, mRNA enzymes achieve gene expression by transcribing the information on the DNA template into mRNA molecules. This is a key step in the process of protein production in organisms. Different types of cells will have different mRNA enzymes in order to transcribe specific mRNA molecules.

[0003] mRNA enzyme is an important biological material that needs to be stored under specific conditions to maintain its stability and activity. It is usually preserved using anhydrous ethanol. The mRNA enzyme raw material needs to be stored at low temperature (-80°C or in liquid nitrogen). It is in a liquid state and is easily contaminated by RNase enzymes in the air.

[0004] After searching, Chinese patent announcement number: CN216710131U discloses a neutral protease storage device, including a storage barrel, carrying rings are installed on both sides of the upper part of the outer end wall of the storage barrel, steel cladding is provided on the upper and lower parts of the outer end wall of the storage barrel, an upper cover is provided on the upper end of the storage barrel, a groove is provided on the top wall of the upper cover, a pumping pump is installed on the upper end of the upper cover, and a discharge pipe is installed on the upper end of the pumping pump; the steel cladding is stainless steel flat steel, and the steel cladding is sleeved on the upper and lower parts of the outer end wall of the storage barrel. When in use, the protruding outer end wall of the storage barrel is wrapped by the steel cladding to prevent the storage barrel from being squeezed and damaged during transportation, thereby effectively improving the strength and safety performance of the storage barrel; and the pumping pump extends to the bottom end of the storage barrel through a pipeline, and the pumping pump is connected to the discharge pipe. When in use, the neutral protease in the storage barrel can be extracted by starting the pumping pump and discharged through the discharge pipe. There is no need to disassemble the upper cover for manual discharge, which is convenient and quick, and effectively improves its functionality and practicality.

[0005] Although the above-mentioned device can realize material extraction without opening the upper cover for manual material extraction by providing a material extraction pump and a material discharge pipe, after the material is extracted, there will be residual enzyme raw materials in the material discharge pipe. The residual raw materials remain on the pipe wall and come into contact with the air and impurities in the air. They are easily contaminated by the RNase enzyme in the air and may deteriorate. The residual deteriorated raw materials may contaminate the extracted materials when the materials are extracted next time. Therefore, a special anti-pollution storage device for mRNA enzyme raw materials is proposed to solve the above-mentioned problem. Utility Model Content

[0006] In order to make up for the above deficiencies, the utility model provides a special anti-pollution storage device for mRNA enzyme raw materials, aiming to improve the problem in the prior art that after the material is taken out of the discharge pipe, some materials will remain in the pipe wall, and will deteriorate after contacting with air and impurities, causing pollution to the subsequently taken out materials.

[0007] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a special anti-pollution storage device for mRNA enzyme raw materials, including a storage barrel, a material pump is installed on the top of the storage barrel, a valve is installed on the output end of the material pump, a connecting pipe is installed on the upper end of the valve, a sealing member is movably connected to the upper part of the connecting pipe, a material conveying member is movably connected to the upper part of the connecting pipe, and the sealing member includes a connecting member.

[0008] As a further description of the above technical solution:

[0009] The sealing member also includes a control sleeve. A sealing plug is arranged inside the connecting member, and the sealing plug is movably connected to the connecting pipe.

[0010] As a further description of the above technical solution:

[0011] The connecting piece comprises a top cover, the top cover is fixedly connected to the sealing plug, a connecting sleeve is fixedly connected to the bottom surface of the top cover, the connecting sleeve is movably connected to the connecting pipe, and a limiting ring is fixedly connected to the lower part of the outer wall of the connecting sleeve.

[0012] As a further description of the above technical solution:

[0013] A plurality of connection ports are provided in the middle of the connection sleeve, and balls are movably connected inside the connection ports.

[0014] As a further description of the above technical solution:

[0015] A control ring is fixedly connected to the middle of the inner wall of the control sleeve, a limiting groove is provided at the lower part of the control sleeve, the limiting ring is movably connected to the limiting groove, and a mounting groove is provided at the upper part of the control sleeve.

[0016] As a further description of the above technical solution:

[0017] A spring is fixedly connected between the mounting groove and the top cover.

[0018] As a further description of the above technical solution:

[0019] An annular groove is provided in the middle of the outer wall of the connecting pipe, and the ball bearing is movably connected to the annular groove.

[0020] As a further description of the above technical solution:

[0021] The material conveying member comprises a mounting cap, which is threadedly connected to the upper portion of the outer wall of the connecting pipe, a material conveying pipe is penetrated through the middle portion of the mounting cap and movably connected thereto, and a fixing ring is fixedly connected to the bottom of the material conveying pipe.

[0022] The utility model has the following beneficial effects:

[0023] 1. In the utility model, by arranging the seal and the connecting pipe and the material conveying member and the connecting pipe to cooperate with each other, the material conveying pipe can be removed for disinfection after the material is conveyed, and the connecting pipe can be dust-proofed by the seal, which is more practical.

[0024] 2. In the utility model, by arranging the cooperation between the connecting piece and the control sleeve, the limit ring, the sealing plug and the spring, the fixing and taking between the sealing piece and the connecting pipe are made more convenient and more practical. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 This is a schematic diagram of the overall three-dimensional structure of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model;

[0026] Figure 2 This is a schematic diagram of the enlarged three-dimensional structure of position A of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model;

[0027] Figure 3 This is a schematic diagram of the partial three-dimensional structure of a material feeding part of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model when in use;

[0028] Figure 4 This is a schematic diagram of the enlarged three-dimensional structure of position B of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model;

[0029] Figure 5 This is a schematic diagram of the cross-sectional three-dimensional structure of a seal and a connecting pipe of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model;

[0030] Figure 6 This is a schematic diagram of the disassembled three-dimensional structure of a seal of a special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model;

[0031] Figure 7 This is a schematic diagram of the split three-dimensional structure of the material feeding part of the special anti-pollution storage device for mRNA enzyme raw materials proposed by the utility model.

[0032] Legend:

[0033] 1. Storage barrel; 2. Extraction pump; 3. Valve; 4. Connecting pipe; 5. Seal; 6. Feeding piece; 51. Connecting piece; 52. Limiting ring; 53. Control sleeve; 54. Sealing plug; 55. Spring; 511. Top cover; 512. Connecting sleeve; 513. Connecting port; 514. Ball bearing; 531. Control ring; 532. Limiting groove; 533. Mounting groove; 41. Ring groove; 61. Mounting cap; 62. Feeding pipe; 63. Fixing ring. DETAILED DESCRIPTION

[0034] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0035] Reference Figure 1 - Figure 3 The utility model provides an embodiment: a special anti-pollution storage device for mRNA enzyme raw materials, including a storage barrel 1 for storing materials, a suction pump 2 is installed on the top of the storage barrel 1, and a pipeline directly connected to the bottom of the storage barrel 1 is installed at its suction end for taking materials, a valve 3 is installed at the output end of the suction pump 2 for controlling the discharge of materials, a connecting pipe 4 is installed at the upper end of the valve 3 for matching and connecting various components, a sealing member 5 is movably connected to the upper part of the connecting pipe 4 for sealing the connecting pipe 4 after taking the materials, a material conveying member 6 is movably connected to the upper part of the connecting pipe 4, and is connected to the connecting pipe 4 when taking materials for taking materials.

[0036] like Figure 5As shown in the figure, the sealing member 5 includes a connecting member 51 for connecting with the connecting pipe 4. The sealing member 5 also includes a control sleeve 53 for controlling the connection between the sealing member 5 and the connecting pipe 4. A sealing plug 54 is arranged inside the connecting member 51. The sealing plug 54 is made of rubber and is used to seal the connecting pipe 4 to prevent dust and other impurities from entering the connecting pipe 4 when no material is taken. The sealing plug 54 is movably connected to the connecting pipe 4. The connecting member 51 includes a top cover 511 for connecting various components. The top cover 511 is fixedly connected to the sealing plug 54. The bottom surface of the top cover 511 is fixedly connected with a connecting sleeve 512 for connecting with the connecting pipe 4. The connecting sleeve 512 is movably connected to the connecting pipe 4. The lower part of the outer wall of the connecting sleeve 512 is fixedly connected to a limiting ring 52 for cooperating with the connection and limiting of the control sleeve 53. A connecting port 513 is provided in the middle of the sleeve 512, and there are multiple connecting ports 513 for cooperating with the installation of the ball 514. The ball 514 can move inside but will not fall out. The connecting port 513 is movably connected with the ball 514 inside to cooperate with the disassembly and assembly between the seal 5 and the connecting pipe 4. A control ring 531 is fixedly connected to the middle of the inner wall of the control sleeve 53 to control the connection between the ball 514 and the ring groove 41. A limiting groove 532 is provided at the lower part of the control sleeve 53 to cooperate with the use of the limiting ring 52, and the limiting ring 52 is movably connected thereto. An installation groove 533 is provided at the upper part of the control sleeve 53 to cooperate with the installation of the spring 55. A spring 55 is fixedly connected between the installation groove 533 and the top cover 511 to cooperate with the movement and resetting of the control sleeve 53.

[0037] Furthermore, an annular groove 41 is provided in the middle of the outer wall of the connecting tube 4 for cooperating with the connection of the ball 514 to cooperate with the fixation between the sealing member 5 and the connecting tube 4, and the ball 514 is movably connected thereto.

[0038] See also Figure 4 and Figure 7 The material conveying member 6 includes a mounting cap 61, which is used to cooperate with the installation between the material conveying member 6 and the connecting pipe 4. The mounting cap 61 is threadedly connected to the upper outer wall of the connecting pipe 4. A material conveying pipe 62 is passed through the middle of the mounting cap 61 and movably connected thereto for conveying materials. A fixing ring 63 is fixedly connected to the bottom of the material conveying pipe 62, which is located between the mounting cap 61 and the connecting pipe 4 and is used to cooperate with the fixation of the material conveying pipe 62.

[0039] Working principle: When in use, when it is necessary to take materials, pull the control sleeve 53 upwards to drive the control ring 531 to move upwards, the spring 55 will be squeezed, and then the overall seal 5 will be pulled upwards. Since the other side of the connecting port 513 loses the limit of the control ring 531, when the seal 5 moves upwards, the ball 514 will gradually withdraw from the annular groove 41 and be pushed outward by the connecting pipe 4. Continuously pull the seal 5 upwards to separate the seal 5 from the connecting pipe 4, and then pass the feed pipe 62 through the mounting cap 61 to make the fixing ring 63 stuck on the inner side of the mounting cap 61, and then tighten the mounting cap 61 and the connecting pipe 4, immediately open the valve 3 and the extraction pump 2, extract the material in the storage barrel 1, and take the materials. After completion, close the feed pump 2 and the valve 3, then separate the mounting cap 61 from the connecting pipe 4, remove the feed pipe 62 together with the fixing ring 63 from the mounting cap 61, disinfect and clean them, then pull the control sleeve 53 on the seal 5 upwards again, and then press the seal 5 toward the connecting pipe 4 to insert the sealing plug 54 into the upper part of the connecting pipe 4, and at the same time move the ball 514 to the annular groove 41, release the control sleeve 53, the spring 55 will push the control sleeve 53 to reset, and at the same time, the limit ring 52 will limit the position of the control sleeve 53 through the limit groove 532, and the control ring 531 will then stay at the connecting port 513, push the ball 514 into the annular groove 41, and the seal 5 and the connecting pipe 4 are stuck.

[0040] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A special anti-pollution storage device for mRNA enzyme raw materials, comprising a storage barrel (1), characterized in that: A material extraction pump (2) is installed on the top of the material storage barrel (1), a valve (3) is installed on the output end of the material extraction pump (2), a connecting pipe (4) is installed on the upper end of the valve (3), a sealing member (5) is movably connected to the upper part of the connecting pipe (4), a material conveying member (6) is movably connected to the upper part of the connecting pipe (4), and the sealing member (5) includes a connecting member (51).

2. The anti-pollution storage device for mRNA enzyme raw materials according to claim 1, characterized in that: The sealing member (5) further comprises a control sleeve (53), and a sealing plug (54) is arranged inside the connecting member (51), and the sealing plug (54) is movably connected to the connecting pipe (4).

3. A special anti-pollution storage device for mRNA enzyme raw materials according to claim 2, characterized in that: The connecting member (51) comprises a top cover (511), the top cover (511) is fixedly connected to the sealing plug (54), a connecting sleeve (512) is fixedly connected to the bottom surface of the top cover (511), the connecting sleeve (512) is movably connected to the connecting pipe (4), and a limiting ring (52) is fixedly connected to the lower part of the outer wall of the connecting sleeve (512).

4. The anti-pollution storage device for mRNA enzyme raw materials according to claim 3, characterized in that: A plurality of connection openings (513) are provided in the middle of the connection sleeve (512), and a ball bearing (514) is movably connected inside the connection opening (513).

5. The anti-pollution storage device for mRNA enzyme raw materials according to claim 4, characterized in that: A control ring (531) is fixedly connected to the middle of the inner wall of the control sleeve (53), a limiting groove (532) is provided at the lower part of the control sleeve (53), the limiting ring (52) is movably connected to the limiting groove, and a mounting groove (533) is provided at the upper part of the control sleeve (53).

6. The anti-pollution storage device for mRNA enzyme raw materials according to claim 5, characterized in that: A spring (55) is fixedly connected between the mounting groove (533) and the top cover (511).

7. The anti-pollution storage device for mRNA enzyme raw materials according to claim 4, characterized in that: An annular groove (41) is provided in the middle of the outer wall of the connecting pipe (4), and the ball (514) is movably connected thereto.

8. The anti-pollution storage device for mRNA enzyme raw materials according to claim 1, characterized in that: The material conveying member (6) comprises a mounting cap (61) which is threadedly connected to the upper portion of the outer wall of the connecting pipe (4); a material conveying pipe (62) is passed through the middle of the mounting cap (61) and is movably connected thereto; a fixing ring (63) is fixedly connected to the bottom of the material conveying pipe (62).

Citation Information

Patent Citations

  • Neutral protease storage device

    CN216710131U