Blood cell test device for full-automatic sample injection of pre-diluted test tube sample

Abstract

The utility model relates to the technical field of medical instruments, in particular to a blood cell test device for full-automatic sample introduction of pre-diluted test tube samples, which comprises a plurality of test tubes, a test tube rack, a test tube rack recognition device, a test tube existence recognition device, an automatic sample introduction disc, a code scanning device, an inverted uniform mixing device, an emergency treatment cabin and a sampling mechanism, test tubes filled with samples are placed on the test tube rack, the test tube rack is placed on the automatic sample feeding disc, the test tubes are driven to move to the test tube rack recognition device, the test tube existence recognition device and the code scanning device for recognition and registration, the test tubes are uniformly mixed through the reverse uniform mixing device and then placed into the emergency treatment bin, and detection is conducted through the sampling mechanism. The test tube is reset after the detection is completed, so that the condition of sample accumulation is greatly reduced, full-automatic sample injection test is realized, and the problem that the test efficiency of an existing blood sample detection device is reduced due to manual intervention is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a blood cell testing device for fully automatic sampling of pre-diluted test tube samples. Background Art

[0002] At present, when blood cell analyzers detect blood samples, the samples are divided into venous whole blood samples, micro blood samples, and pre-diluted samples. Among them, venous whole blood samples are usually 2 ml of venous whole blood samples; micro blood samples are usually about 60 microliters of peripheral blood whole blood samples; and pre-diluted samples are usually pre-prepared samples of 20 microliters of samples mixed with quantitative diluents. At present, there are mature fully automatic sampling test solutions for venous whole blood samples and micro whole blood samples, but it is still difficult for infants and other elderly people who have difficulty in blood collection to collect 60 microliters of samples required for the micro whole blood mode. The current solution is a manual pre-dilution solution. First, manually put the predetermined test tube (bullet or hose) into the emergency room; then click the instrument's discharge button to wait for the instrument to discharge the quantitative diluent; among them, draw a sample (usually 20 microliters) from the patient and add it to the predetermined test tube; secondly, manually mix the sample, enter the patient information, use the instrument to test the sample in the emergency department, and upload the test results to the data management system (LIS); in addition, associate the patient's order information on the LIS; finally, review and publish the report.

[0003] The above operations need to be repeated for each patient, and the following problems are prone to occur: manual mixing may result in insufficient mixing, and some laboratories that use bullet-shaped test tubes need to use finger flicking to mix, which may cause certain harm to the operator; manual input of information may result in the possibility of inputting wrong information, and in severe cases, the test results may be cross-matched (test results of AB patients are exchanged); the test is cumbersome and the degree of automation is low. When the sample size is large (such as maternal and child hospitals and children's hospitals), the above operations require more manual intervention, resulting in slow testing speed and patient backlog. Utility Model Content

[0004] The utility model aims to provide a blood cell testing device for fully automatic sampling of pre-diluted test tube samples, aiming to solve the problem that the test efficiency of the existing blood sample testing device is reduced due to manual intervention.

[0005] To achieve the above object, the utility model provides a blood cell testing method for fully automatic sampling of pre-diluted test tube samples, comprising the following steps:

[0006] S1 injects diluent into the test tubes on the test tube rack;

[0007] S2: placing the test tube containing the sample on the test tube rack, and placing the test tube rack on the automatic sample introduction tray;

[0008] S3: the automatic sample feeder moves the test tube containing the sample to the test tube rack identification device, and registers the information through the code scanning device and the test tube presence identification device, first registering the information;

[0009] S4: the automatic sample feeder pushes the test tube rack to move to the inversion and mixing device, and the inversion and mixing device makes a judgment based on the first registration information, and vibrates and mixes the test tube containing the sample based on the judgment result;

[0010] S5 The emergency room pushes the mixed test tube to the bottom of the sampling mechanism, and performs a pre-dilution test on the sample in the test tube through the sampling mechanism;

[0011] S6 The emergency room moves the test tube after the test to the inversion mixing device, and puts the test tube back into the test tube rack through the inversion mixing device;

[0012] S7 repeats step S4 to step S6 until all the test tubes on the test tube rack have completed the test.

[0013] Wherein, injecting diluent into the test tubes on the test tube rack comprises:

[0014] S11 The test tube rack identification device registers information of the test tubes on the test tube rack to obtain second registration information;

[0015] S12: an inversion and mixing device picks up the test tube on the test tube rack based on the second registration information, and places the test tube into the emergency chamber;

[0016] S13: the emergency room pushes the test tube to the bottom of the sampling mechanism, and injects a diluent into the test tube through the sampling mechanism;

[0017] S14 The emergency room resets the test tube after the diluent is injected, and puts the test tube injected with the diluent back into the test tube rack through the inversion mixing device;

[0018] S15 repeats step S12 to step S14 until all the test tubes on the test tube rack have completed the injection of the diluent.

[0019] The test tube rack identification device registers information of the test tubes on the test tube rack to obtain second registration information, including the following steps:

[0020] S111: placing the test tube rack containing the test tube on the automatic sample introduction tray, and starting fully automatic liquid discharge;

[0021] S112: the automatic sample feeder drives the test tube rack to the test tube rack identification device, and registers information through the code scanning device and the test tube presence identification device to obtain second registration information.

[0022] The sample may be a pre-diluted sample, a normal venous whole blood sample or a trace whole blood sample.

[0023] In a second aspect, a blood cell testing device for fully automatic injection of pre-diluted test tube samples is used by the blood cell testing method for fully automatic injection of pre-diluted test tube samples described in the first aspect.

[0024] It includes multiple test tubes, test tube racks, test tube rack identification devices, test tube presence identification devices, automatic sample trays, code scanning devices, inversion mixing devices, emergency chambers and sampling mechanisms.

[0025] A plurality of test tubes are arranged on the test tube rack, the test tube rack is arranged on one side of the test tube rack identification device, the test tube presence identification device is arranged on one side of the test tube rack, the test tube rack identification device is arranged on a side of the test tube rack away from the test tube presence identification device, the automatic sample feeder is arranged on one side of the test tube presence identification device, the code scanning device is arranged opposite to the test tube presence identification device, the emergency warehouse is arranged on one side of the code scanning device, the sampling mechanism is arranged on one side of the emergency warehouse, and the inversion mixing device is arranged on one side of the sampling mechanism.

[0026] Wherein, the test tube has a code scanning label, and the code scanning label is located on the outside of the test tube.

[0027] Wherein, the test tube has a conical bottom, which is conducive to the detection of trace samples.

[0028] The utility model discloses a blood cell testing device for fully automatic sampling of pre-diluted test tube samples, wherein the test tube is an empty test tube in the liquid discharge stage, and finally the liquid is discharged under the sampling mechanism and returned to the outside of the instrument; in the test stage, the test tube is loaded with a sample to be tested (a mixture of diluent and sample), and finally the sample is sampled under the sampling needle of the sampling mechanism for subsequent testing (the same process as the conventional test); the test tube rack is used to place a plurality of the test tubes, and the test tube rack identification device is provided with an RFID tag on the edge of the test tube rack, and the test tube rack identification device reads the content in the tag through the RFID technology to determine the type of the test tube where the sample is located, so as to prepare for selecting the mixing method; the tube presence or absence identification device is a reflective optical coupling device, and the light is irradiated onto the reflector and then reflected back onto the receiver, and each test tube position of the test tube rack passes through the light path in turn, and when there is a test tube, the light is blocked and cannot irradiate the receiver On the top, it can be detected whether there is a test tube on the test tube position on the test tube rack, so as to determine whether drainage or mixing testing is needed; the code scanning device rotates the test tube through the motor and its roller, and its scanner recognizes the barcode or QR code information on the test tube, so that the instrument control unit obtains LIS information and obtains the test mode applied for by the clinician, so as to match the test result with the patient; the inversion and mixing device is equipped with a test tube clamp, which can clamp the test tube on the test tube rack and move it upward. When the emergency warehouse moves under the test tube clamp, the test tube can be placed in the emergency warehouse, and the pre-dilution test tube can be placed in the pre-dilution test tube vibration mixing position; the test tube clamp can be rotated to achieve inversion mixing of conventional venous whole blood; the emergency warehouse is equipped with a bullet-shaped test tube position, a conventional test tube position, and a pre-dilution test tube vibration mixing position, which can transport the test tube to the sampling needle of the sampling mechanism. The sampling mechanism adds diluent to the empty pre-dilution test tube through the sampling needle during the discharge process, and draws quantitative samples from the test tube through the sampling needle during the test process and distributes them to various test modules of the blood cell analyzer to complete the sample test. When testing the sample, the inspector uses the automatic discharge function to prepare the pre-dilution test tube, the clinician opens a test application form, the inspector prints the barcode, sticks the barcode on the pre-dilution test tube, and draws blood. The inspector puts the sample into the multi-injection test tube rack and places the test tube rack on the automatic injection tray to automatically perform the test process. This application reduces manual intervention and effectively improves the detection efficiency of the sample, greatly reduces the accumulation of samples, and realizes fully automatic sampling and testing to solve the problem of reduced test efficiency due to manual intervention in existing blood sample detection methods. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 The utility model discloses a flow chart of a blood cell testing method for fully automatic sampling of pre-diluted test tube samples.

[0031] Figure 2 The utility model is a schematic diagram of the structure of a blood cell testing device for fully automatic sampling of pre-diluted test tube samples.

[0032] Figure 3 (a) is a schematic diagram of the structure of the test tube, and (b) is a cross-sectional view of the test tube.

[0033] Figure 4 It is a schematic diagram of the structures of a test tube, a test tube rack identification device and a test tube rack.

[0034] Figure 5 It is a schematic diagram of the structure of a device for identifying the presence or absence of a test tube.

[0035] Figure 6 It is a structural schematic diagram of a code scanning device.

[0036] Figure 7 It is a schematic diagram of the structure of the inversion mixing device.

[0037] Figure 8 This is a structural diagram of the emergency room.

[0038] Fig. 9 This is a schematic diagram of the sampling mechanism structure.

[0039] 1-test tube, 2-test tube rack, 3-test tube rack identification device, 4-test tube presence identification device, 5-automatic sample feeder, 6-code scanning device, 7-inversion mixing device, 8-emergency chamber, 9-sampling mechanism. DETAILED DESCRIPTION

[0040] The embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention.

[0041] See also Figure 1 The utility model provides a blood cell testing method for fully automatic sampling of a pre-diluted test tube 1 sample, comprising the following steps:

[0042] S1 injects diluent into test tube 1 on test tube rack 2;

[0043] S11 The test tube rack identification device 3 registers information of the test tube 1 on the test tube rack 2 to obtain second registration information;

[0044] S111: placing the test tube rack 2 containing the test tube 1 on the automatic sample introduction tray 5, and starting the fully automatic liquid discharge;

[0045] Specifically, the test tube 1 that needs to be drained is placed on the test tube rack 2, the test tube rack 2 is placed on the automatic sample feeder tray 5, and a button on the instrument screen is clicked to start fully automatic draining.

[0046] S112: the automatic sample feeder 5 drives the test tube rack 2 to the test tube rack identification device 3, and registers information through the code scanning device 6 and the test tube presence identification device 4 to obtain second registration information.

[0047] Specifically, the automatic sampling tray 5 will push the test tube rack 2 along the y-coordinate direction to the test tube rack identification device 3, push the automatic sampling tray 5 to push the test tube rack 2 along the x-coordinate direction so that the test tube 1 passes through the test tube presence identification device 4, and records whether there is the test tube 1 in the tube position on the test tube rack 2, and continue to push it along the x-coordinate direction to the barcode scanning device 6 to scan the barcode and record and upload the test tube barcode related information.

[0048] S12: the inversion and mixing device 7 picks up the test tube 1 on the test tube rack 2 based on the second registration information, and puts the test tube 1 into the emergency chamber 8;

[0049] Specifically, the automatic sampling tray 5 continues to push the test tube rack 2 along the x-coordinate direction so that the test tube 1 reaches under the test tube clamp of the inversion mixing device 7. According to whether the test tube 1 is recorded by the automatic sampling tray 5, the test tube clamp of the inversion mixing device 7 clamps the test tube 1 that needs to be drained and runs along the z-coordinate direction. The emergency bin 8 moves out of the bin in the opposite direction of the y-coordinate. The inversion mixing device 7 runs the test tube 1 in the opposite direction of the x-coordinate and places it on the pre-dilution test tube 1 vibration mixing position of the emergency bin 8.

[0050] S13: the emergency chamber 8 pushes the test tube 1 to the bottom of the sampling mechanism 9, and injects a diluent into the test tube 1 through the sampling mechanism 9;

[0051] Specifically, the emergency chamber 8 structure moves back to the chamber along the y coordinate direction to push the test tube 1 under the sampling needle of the sampling mechanism 9, and the sampling needle is inserted in the opposite direction of the z coordinate. The sampling syringe of the sampling mechanism 9 injects a quantitative diluent and then retracts the needle.

[0052] S14 The emergency chamber 8 resets the test tube 1 after the diluent is injected, and puts the test tube 1 injected with the diluent back into the test tube rack 2 through the inversion mixing device 7;

[0053] Specifically, the emergency warehouse 8 structure pushes the test tube 1 to the bottom of the test tube clamp of the inversion mixing device 7 when it moves out of the warehouse in the opposite direction of the y coordinate. The test tube clamp of the inversion mixing device 7 clamps the test tube 1. After the emergency warehouse 8 structure runs back to the warehouse in the y direction and resets, the inversion mixing device 7 runs the test tube 1 in the opposite direction of the z coordinate and puts it back into the test tube rack 2.

[0054] S15 repeats step S12 to step S14 until all the test tubes 1 on the test tube rack 2 have been injected with the diluent.

[0055] Specifically, step S12 to step S14 are repeated until all the test tubes 1 on the test tube rack 2 are added with the quantitative diluent.

[0056] S2: placing the test tube 1 containing the sample on the test tube rack 2, and placing the test tube rack 2 on the automatic sample feeder 5;

[0057] The sample may be a pre-diluted sample, a normal venous whole blood sample or a micro-amount whole blood sample.

[0058] Specifically, the sample to be tested (the test tube 1) is placed on the test tube rack 2, and the test tube rack 2 is placed on the automatic sample introduction tray 5, and the button on the instrument screen is clicked to start the automatic sample introduction test.

[0059] S3: the automatic sample feeder 5 moves the test tube 1 containing the sample to the test tube rack identification device 3, and registers the information through the code scanning device 6 and the test tube presence identification device 4, first registering the information;

[0060] Specifically, the automatic sampling tray 5 pushes the test tube rack 2 along the y-coordinate direction to the test tube rack identification device 3, the automatic sampling tray 5 pushes the test tube rack 2 along the x-coordinate direction so that the test tube 1 passes through the test tube presence identification device 4, and records whether there is the test tube 1 in the test tube position, and the automatic sampling tray 5 pushes the test tube rack 2 along the x-coordinate direction so that the test tube 1 is to the position of the code scanning device 6, identifies and records the current test tube 1 information.

[0061] S4: the automatic sample feeder 5 pushes the test tube rack 2 to move to the inversion mixing device 7, and the inversion mixing device 7 makes a judgment based on the first registration information, and vibrates and mixes the test tube 1 containing the sample based on the judgment result;

[0062] Specifically, the automatic sample feeder 5 continues to push the test tube rack 2 along the x-coordinate direction so that the test tube 1 reaches below the test tube clamp of the inverted mixing device 7, and inquires about the test mode applied by the clinician according to the test tube rack 2 information, the test tube 1 information, and the barcode information recorded by the automatic sample feeder 5, and determines whether the mode matches the information. If not, the test tube 1 is skipped and an alarm is sounded, and the corresponding mixing process is executed according to the test mode: the pre-diluted sample is placed on the pre-diluted sample mixing device of the emergency chamber 8 for vibration mixing,

[0063] S5 The emergency chamber 8 pushes the mixed test tube 1 to the bottom of the sampling mechanism 9, and performs a pre-dilution test on the sample in the test tube 1 through the sampling mechanism 9;

[0064] Specifically, the emergency chamber 8 structure moves back to the chamber along the y-coordinate direction to push the pre-diluted sample to below the sampling needle of the sampling mechanism 9 to perform a pre-dilution test.

[0065] S6 The emergency room 8 moves the test tube 1 after the test to the inversion mixing device 7, and puts the test tube 1 back into the test tube rack 2 through the inversion mixing device 7;

[0066] Specifically, the test tube clamp of the inversion and mixing device 7 clamps the test tube 1, and after the emergency chamber 8 structure returns to the chamber and resets along the y coordinate direction, the inversion and mixing device 7 puts the test tube 1 back into the test tube rack 2 along the opposite z coordinate direction.

[0067] S7 repeats step S4 to step S6 until all the test tubes 1 on the test tube rack 2 have completed the test.

[0068] Specifically, steps S4 to S6 are repeated until all the test tubes 1 on the test tube rack 2 are tested, wherein the sample type may be a pre-diluted sample, a normal blood venous whole blood sample, or a trace whole blood sample; and the test process may include adding pre-diluted samples, normal blood venous whole blood samples, or a trace whole blood sample to the automatic sample tray 5.

[0069] See also Figures 2 to 9 In the second aspect, a blood cell testing device for fully automatic injection of a pre-diluted test tube 1 sample is used by the blood cell testing method for fully automatic injection of a pre-diluted test tube 1 sample described in the first aspect.

[0070] It includes a plurality of test tubes 1, a test tube rack 2, a test tube rack identification device 3, a test tube presence identification device 4, an automatic sample feeder 5, a code scanning device 6, an inversion mixing device 7, an emergency chamber 8 and a sampling mechanism 9.

[0071] The plurality of test tubes 1 are arranged on the test tube rack 2, the test tube rack 2 is arranged on one side of the test tube rack identification device 3, the test tube presence identification device 4 is arranged on one side of the test tube rack 2, the test tube rack identification device 3 is arranged on the side of the test tube rack 2 away from the test tube presence identification device 4, the automatic sample feeder 5 is arranged on one side of the test tube presence identification device 4, the code scanning device 6 is arranged opposite to the test tube presence identification device 4, the emergency chamber 8 is arranged on one side of the code scanning device 6, the sampling mechanism 9 is arranged on one side of the emergency chamber 8, and the inversion mixing device 7 is arranged on one side of the sampling mechanism 9.

[0072] The test tube 1 has a code scanning label, and the code scanning label is located on the outside of the test tube 1. The test tube 1 has a conical bottom, which is conducive to the detection of trace samples and can form a certain height of a small amount of liquid, which is convenient for detection by detection instruments.

[0073] In this embodiment, the test tube 1 is an empty test tube in the drainage stage, and is finally drained under the sampling mechanism 9 and returned to the outside of the instrument; in the test stage, it is filled with a sample to be tested (a mixture of diluent and sample) and is finally sampled under the sampling needle of the sampling mechanism 9 for subsequent testing (the same process as conventional testing); the test tube rack 2 is used to place multiple test tubes 1, and the test tube rack identification device 3: an RFID tag is attached to the edge of the test tube rack 2, and the test tube rack identification device 3 reads the content in the tag through RFID technology to determine the type of test tube 1 where the sample is located, so as to prepare for selecting a mixing method; a tube presence identification device: a reflective optical coupling device, light is irradiated onto the reflector and then reflected back to the receiver, and each test tube position of the test tube rack 2 passes through the light path in turn. When there is a test tube 1, the light is blocked and cannot be irradiated onto the receiver, so that the test tube rack 2 can be detected. Whether there is a test tube 1 on the test tube position is determined to determine whether drainage or mixing testing is required; the code scanning device 6 rotates the test tube 1 through a motor and its roller, and its scanner identifies the barcode or QR code information on the test tube 1, so that the instrument control unit obtains LIS information and obtains the test mode applied for by the clinician, thereby matching the test result with the patient; the inversion and mixing device 7 is equipped with a test tube clamp, which can clamp the test tube 1 on the test tube rack 2 and move it upward. When the emergency bin 8 moves under the test tube clamp, the test tube 1 can be placed in the emergency bin 8, and the pre-dilution test tube 1 can be placed in the pre-dilution test tube 1 vibration mixing position; the test tube clamp can be rotated to achieve inversion mixing of conventional venous whole blood; the emergency bin 8 is equipped with a bullet-shaped test tube position, a conventional test tube, and a pre-dilution test 1 vibration mixing position, which can transport the test tube 1 to the sampling needle of the sampling mechanism 9. The sampling mechanism 9 adds diluent to the empty pre-dilution test tube 1 through the sampling needle during the discharge process, and draws quantitative samples from the test tube 1 through the sampling needle during the test process and distributes them to various test modules of the blood cell analyzer to complete the sample test.

[0074] Beneficial effects:

[0075] A. Fully automatic liquid discharge process simplifies the operation steps for test operators to perform pre-dilution sample testing;

[0076] B. The pre-diluted samples are mixed by the instrument in a standardized manner to eliminate the errors caused by manual mixing differences;

[0077] C. Pre-diluted samples are automatically scanned and matched with LIS information, without the need for manual scanning or input of patient information;

[0078] D. Fully automatic sample injection function, effectively solving the problem of patient backlog or sample backlog when there are many patients;

[0079] E. Use the information equipment (LIS, etc.) of common venous testing procedures without adding additional costs.

[0080] The above disclosure is only a preferred embodiment of the blood cell testing device for fully automatic injection of pre-diluted test tube samples of the present invention. Of course, this cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that implementing all or part of the processes of the above embodiments and making equivalent changes according to the claims of the present invention still fall within the scope covered by the utility model.

Claims

1. A blood cell testing device for fully automatic injection of pre-diluted test tube samples, characterized in that: It includes multiple test tubes, a test tube rack, a test tube rack identification device, a test tube presence identification device, an automatic sample feeder, a code scanning device, an inversion mixing device, an emergency chamber and a sampling mechanism; A plurality of test tubes are arranged on the test tube rack, the test tube rack is arranged on one side of the test tube rack identification device, the test tube presence identification device is arranged on one side of the test tube rack, the test tube rack identification device is arranged on a side of the test tube rack away from the test tube presence identification device, the automatic sample feeder is arranged on one side of the test tube presence identification device, the code scanning device is arranged opposite to the test tube presence identification device, the emergency warehouse is arranged on one side of the code scanning device, the sampling mechanism is arranged on one side of the emergency warehouse, and the inversion mixing device is arranged on one side of the sampling mechanism.

2. A blood cell testing device for fully automatic injection of pre-diluted test tube samples, characterized in that: The test tube has a code scanning label, and the code scanning label is located on the outside of the test tube.

3. A blood cell testing device for fully automatic injection of pre-diluted test tube samples, characterized in that: The test tube has a conical bottom, which is conducive to the detection of trace samples.

Images