Cell cryopreservation bag suitable for exhausting cell mixed liquid

Abstract

The utility model relates to the technical field of cell cryopreservation bags, and discloses a cell cryopreservation bag suitable for exhausting cell mixed liquid, which comprises a bag body, and a connecting mechanism is arranged at the bottom end of the bag body; the connecting mechanism comprises a positioning pipe, the left end of the positioning pipe is fixedly connected with an air pipe, the inner wall of the positioning pipe is elastically connected with a connecting pipe through a connecting spring, the outer wall of the connecting pipe is fixedly connected with a baffle, the inner wall of the bottom end of the positioning pipe is rotatably connected with a rotating column, and the outer wall of the bottom end of the rotating column is fixedly connected with a positioning plate. The top end of the rotating column is fixedly connected with an extrusion plate, and a sealing film is arranged on the inner wall of the left side of the positioning pipe. According to the utility model, when liquid needs to be fed, the limit of the screw is removed, and then the rotating column is rotated, so that the extrusion plate extrudes the corresponding connecting pipe, and the connecting pipe moves to a certain extent, thereby achieving the purpose of feeding liquid or exhausting air, and avoiding needle holes without using an injector.

Description

Technical Field

[0001] The utility model relates to the technical field of cell freezing bags, in particular to a cell freezing bag suitable for exhausting a cell mixed solution. Background Art

[0002] The cell mixture venting cell freezing bag is a medical device specially designed for storing and transporting cell mixtures while being able to remove excess gas in the bag.

[0003] After searching, Chinese patent announcement number: CN217136613U discloses a cell freezing bag suitable for exhausting cell mixture. The utility model includes a freezing bag body, and the outer surface of the freezing bag body is provided with a transparent surface. When removing bubbles, the staff lightly hits the freezing bag body with their fingers, so that the tiny gas inside the suspension preparation also floats out. Due to the characteristics of the gas, the gas will be retained in the bubble chamber. At this time, the staff can extract the gas by inserting the injection tube through the syringe. As the gas is extracted, the freezing bag body will gradually be compressed, thereby squeezing the gas above the inside of the freezing bag body into the bubble chamber. At the same time, it can be intuitively observed through the transparent surface. The freezing bag body is made of fluorinated ethylene propylene copolymer. This material has no cytotoxicity and tissue toxicity, is very suitable for the storage of cytokines and other biological materials, has good flexibility, and reduces the chance of cracking of the freezing bag body.

[0004] Although the above technology has certain improvements, a syringe is required to extract the gas. When using a syringe, the needle needs to be aligned with the injection tube first, and then the needle is inserted into the injection tube. In addition, caution is required during operation, which reduces the operating efficiency. At the same time, there is a pinhole after the needle is inserted. The pinhole setting may lead to poor sealing. Therefore, a cell freezing bag suitable for exhausting cell mixture is proposed to solve the above problems. Utility Model Content

[0005] In order to make up for the above shortcomings, the utility model provides a cell freezing bag suitable for exhausting the cell mixture, aiming to improve the troublesome problem of inserting a needle into a sample injection tube in the prior art.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a cell freezing bag suitable for exhausting a cell mixture, comprising a bag body, wherein a connecting mechanism is provided at the bottom end of the bag body;

[0007] The connecting mechanism includes a positioning tube, the left end of the positioning tube is fixedly connected to the air pipe, the inner wall of the positioning tube is elastically connected to the connecting tube through a connecting spring, the outer wall of the connecting tube is fixedly connected to a baffle, the bottom inner wall of the positioning tube is rotatably connected to a rotating column, the bottom outer wall of the rotating column is fixedly connected to a positioning plate, the top of the rotating column is fixedly connected to an extrusion plate, the left inner wall of the positioning tube is provided with a sealing film, the right end of the positioning tube is fixedly connected to a liquid inlet pipe, and the outer wall of the positioning tube is provided with a dustproof mechanism.

[0008] As a further description of the above technical solution:

[0009] The bottom end of the positioning tube is fixedly connected to a limiting seat, the inner wall of the limiting seat is threadedly connected with a screw, the bottom end of the positioning plate is provided with a screw hole, and the top end of the screw is threadedly connected to the inner wall of the screw hole.

[0010] As a further description of the above technical solution:

[0011] One end of the connecting spring is fixedly connected to the inner wall of the positioning tube, and the other end of the connecting spring is fixedly connected to the top of the connecting tube. The outer walls of the connecting tube and the baffle are both slidably connected to the inner wall of the positioning tube.

[0012] As a further description of the above technical solution:

[0013] The bottom end of the connecting pipe is provided with an inclined surface, and the outer wall of the extrusion plate is in contact with the bottom end of the connecting pipe.

[0014] As a further description of the above technical solution:

[0015] The top end of the positioning tube is fixedly connected to the bottom end of the bag body, and the outer wall of the extrusion plate is rotatably connected to the inner wall of the positioning tube.

[0016] As a further description of the above technical solution:

[0017] The dustproof mechanism comprises a dustproof ring, a positioning block is fixedly connected to the front end of the positioning tube, and the inner wall of the dustproof ring is elastically connected to a socket via a return spring.

[0018] As a further description of the above technical solution:

[0019] The inner side wall of the dustproof ring is slidably connected to the outer wall of the positioning tube.

[0020] As a further description of the above technical solution:

[0021] One end of the reset spring is fixedly connected to the outer wall of the socket, the other end of the reset spring is fixedly connected to the inner wall of the dust ring, the outer wall of the socket is slidably connected to the inner wall of the dust ring, and the outer wall of the socket is plugged into the inner wall of the positioning block.

[0022] The utility model has the following beneficial effects:

[0023] 1. In the utility model, by the cooperation between the connecting mechanism and the bag body and other structures, when liquid needs to be added, the limit of the screw is released and then the rotating column is rotated, so that the extrusion plate squeezes the corresponding connecting tube, causing the connecting tube to move to a certain extent, thereby achieving the purpose of liquid addition or exhaust, without using a syringe to avoid the appearance of pinholes.

[0024] 2. In the utility model, by cooperating with each other among the dustproof mechanism and other structures, when the bag body is not needed, the plug-in socket is moved to release the limit of the plug-in socket, and then the dustproof ring is moved downward, and then the plug-in column is loosened so that the plug-in column fixes the dustproof ring, thereby achieving the purpose of dustproof. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 This is an overall three-dimensional schematic diagram of a cell freezing bag suitable for exhausting a cell mixture solution proposed by the utility model;

[0026] Figure 2 This is a schematic diagram of the internal cross-section of a dustproof ring of a cell freezing bag suitable for exhausting a cell mixture solution proposed by the utility model;

[0027] Figure 3 This is a schematic diagram of the internal cross-section of a positioning tube of a cell freezing bag suitable for exhausting a cell mixture solution proposed by the utility model;

[0028] Figure 4 The utility model provides a schematic diagram of a split rotary column and a positioning tube of a cell freezing bag suitable for exhausting a cell mixture.

[0029] Legend:

[0030] 1. Bag body; 2. Connecting mechanism; 201. Positioning tube; 202. Connecting spring; 203. Air pipe; 204. Connecting tube; 205. Sealing film; 206. Baffle; 207. Rotating column; 208. Positioning plate; 209. Limiting seat; 210. Screw; 211. Extrusion plate; 212. Liquid inlet pipe; 3. Dustproof mechanism; 301. Dustproof ring; 302. Reset spring; 303. Connecting seat; 304. Positioning block. DETAILED DESCRIPTION

[0031] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0032] Reference Figure 1 The utility model provides an embodiment: a cell freezing bag suitable for exhausting a cell mixture, comprising a bag body 1, the bag body 1 being a cell storage bag for storing a cell mixture, and a connecting mechanism 2 being provided at the bottom end of the bag body 1; the cell mixture can be injected through the connecting mechanism 2, and the air inside the bag body 1 can be exhausted.

[0033] Reference Figure 3-Figure 4 The connecting mechanism 2 includes a positioning tube 201, the left end of which is fixedly connected to an air pipe 203, and the air pipe 203 is used to discharge the gas. The inner wall of the positioning tube 201 is elastically connected to a connecting tube 204 through a connecting spring 202. The movement of the connecting tube 204 can open the air pipe 203. The outer wall of the connecting tube 204 is fixedly connected to a baffle 206, and the movement trajectories of the two are medical. The movement of the baffle 206 can open the air pipe 203. The inner wall of the bottom end of the positioning tube 201 is rotatably connected to a rotating column 207, and the outer wall of the bottom end of the rotating column 207 is fixedly connected to a positioning plate 208. The movement trajectory of the rotating column 207 is the same as that of the positioning plate 208. The rotating column 207 is rotated by a piston It is rotatably connected to the inner wall of the positioning tube 201, and the top of the rotating column 207 is fixedly connected with an extrusion plate 211. The three ends of the extrusion plate 211 are set as arc surfaces, and the arc surface is set to facilitate extrusion. A sealing film 205 is set on the inner wall of the left side of the positioning tube 201. The sealing film of the bottle mouth is usually made of food silicone, which is an inorganic polymer colloid material formed by condensation of silicic acid and can play a sealing effect. The right end of the positioning tube 201 is fixedly connected with a liquid inlet pipe 212, and the liquid inlet pipe 212 can inject a cell mixture. The outer wall of the positioning tube 201 is provided with a dustproof mechanism 3, and the dustproof mechanism 3 is used to prevent dust from entering the inner wall of the bottom end of the positioning tube 201, that is, the horizontal through hole of the sealing film 205.

[0034] Reference Figure 3-Figure 4The bottom end of the positioning tube 201 is fixedly connected to a limited seat 209, and the limited seat 209 is L-shaped. The inner wall of the limited seat 209 is threadedly connected with a screw 210, and the screw 210 can play a limiting role. A screw hole is provided at the bottom end of the positioning plate 208, and four groups of screw holes are provided. The four groups are convenient for the extrusion plate 211 to rotate 180 degrees or 90 degrees. The top end of the screw 210 is threadedly connected to the inner wall of the screw hole. The threaded connection between the two plays a limiting role on the rotating column 207. One end of the connecting spring 202 is fixedly connected to the inner wall of the positioning tube 201, and the other end of the connecting spring 202 is fixedly connected to the top of the connecting tube 204. The elasticity of the connecting spring 202 enables the connecting tube 204 to have a reset function. The outer walls of the connecting tube 204 and the baffle 206 are both slidably connected to the inner wall of the positioning tube 201. The connecting tube 204 is provided with two groups, which are respectively located on the left and right sides of the rotating column 207. The left end of the left connecting tube 204 is connected to the right end of the air pipe 203, and the right end of the right connecting tube 204 is connected to the left end of the liquid inlet pipe 212. There are also two groups of baffles 206. When the left baffle 206 contacts the air pipe 203, the air pipe 203 is in a closed state. When the right baffle 206 contacts the liquid inlet pipe 212, the liquid inlet pipe 212 is in a closed state.

[0035] Reference Figure 3-Figure 4 The bottom end of the connecting tube 204 is provided with an inclined surface, and the outer wall of the extrusion plate 211 contacts the bottom end of the connecting tube 204. When the arc surface of the extrusion plate 211 contacts the inclined surface of the connecting tube 204, the connecting tube 204 can be pushed up. The top end of the positioning tube 201 is fixedly connected to the bottom end of the bag body 1, and the positioning tube 201 can be supported by the bottom end of the bag body 1. The outer wall of the extrusion plate 211 is rotatably connected to the inner wall of the positioning tube 201, and the rotation of the two can make the connecting tube 204 move vertically.

[0036] Reference Figure 1-Figure 2The dustproof mechanism 3 includes a dustproof ring 301, which can perform dustproof function. The front end of the positioning tube 201 is fixedly connected with a positioning block 304. The positioning block 304 is provided with two groups, one group is close to the top and the other group is close to the bottom. When the dustproof ring 301 is located at the top, the bag body 1 can enter liquid or exhaust gas. When it is located at the bottom, liquid cannot be entered or exhaust gas cannot be discharged. The inner wall of the dustproof ring 301 is elastically connected with a socket 303 through a reset spring 302. The socket 303 is composed of a group of cylinders and a group of square plates. The inner side wall of the dustproof ring 301 slides It is movably connected to the outer wall of the positioning tube 201, and can prevent dust or release the dustproof effect through the movement of the dustproof ring 301. One end of the reset spring 302 is fixedly connected to the outer wall of the socket 303, and the other end of the reset spring 302 is fixedly connected to the inner wall of the dustproof ring 301. The outer wall of the socket 303 is slidably connected to the inner wall of the dustproof ring 301. The elasticity of the reset spring 302 makes the socket 303 have reset and limit functions. The outer wall of the socket 303 is plugged into the inner wall of the positioning block 304, and the two are plugged in to prevent the dustproof ring 301 from moving.

[0037] Working principle: When the cell mixture needs to be discharged into the inner wall of the bag body 1, first move the socket 303 to the left end to release the limit of the socket 303 on the lower positioning block 304, and then the dust ring 301 can be moved upward until the dust ring 301 and the upper positioning block 304 are on the same horizontal plane, and then the socket 303 can be released. At this time, due to the elasticity of the reset spring 302, the socket 303 is reset and then plugged and fixed with the upper positioning block 304, so that the same through hole of the sealing film 205 is opened.

[0038] When the through hole is opened, the cell mixture can be injected from the right end, so that the cell mixture enters the inner wall of the bag body 1 from the liquid inlet pipe 212. When the injection is completed, the screw 210 is rotated to release the limit of the screw 210 and the positioning plate 208, and then the rotating column 207 is rotated so that the rotating column 207 drives the squeezing plate 211 to rotate, and the rotation angle is ninety degrees. When the squeezing plate 211 rotates, the baffle 206 at the right end will be pushed upward, thereby closing the liquid inlet pipe 212. At the same time, the squeezing plate 211 will not contact the connecting pipe 204 on the left, and then the connecting pipe 204 moves downward under the elastic action of the connecting spring 202, and then connects with the air pipe 203 on the left, so that the exhaust operation can be performed, and then the bag body 1 is turned upside down as a whole to pinch the bag body 1, so that the air enters the sealing film 205 through the through hole, and the gas is discharged through the sealing film 205. When the bag body 1 is not needed, Figure 3 The squeezing plate 211 in the middle rotates 90 degrees, so that the squeezing plate 211 squeezes the two groups of connecting tubes 204, and then the two groups of connecting tubes 204 drive the baffle 206 to move upward, so as to close the contact with the two groups of air pipes 203, and then the bag body 1 can be stored.

[0039] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A cell freezing bag suitable for exhausting a cell mixture, comprising a bag body (1), characterized in that: The bottom end of the bag body (1) is provided with a connecting mechanism (2); The connecting mechanism (2) comprises a positioning tube (201), the left end of the positioning tube (201) is fixedly connected to an air pipe (203), the inner wall of the positioning tube (201) is elastically connected to a connecting tube (204) via a connecting spring (202), the outer wall of the connecting tube (204) is fixedly connected to a baffle (206), the inner wall of the bottom end of the positioning tube (201) is rotatably connected to a rotating column (207), the outer wall of the bottom end of the rotating column (207) is fixedly connected to a positioning plate (208), the top of the rotating column (207) is fixedly connected to an extrusion plate (211), the inner wall of the left side of the positioning tube (201) is provided with a sealing film (205), the right end of the positioning tube (201) is fixedly connected to a liquid inlet pipe (212), and the outer wall of the positioning tube (201) is provided with a dustproof mechanism (3).

2. The cell freezing bag suitable for exhausting the cell mixture according to claim 1, characterized in that: The bottom end of the positioning tube (201) is fixedly connected to a limiting seat (209), the inner wall of the limiting seat (209) is threadedly connected with a screw (210), the bottom end of the positioning plate (208) is provided with a screw hole, and the top end of the screw (210) is threadedly connected to the inner wall of the screw hole.

3. The cell freezing bag suitable for exhausting the cell mixture according to claim 1, characterized in that: One end of the connecting spring (202) is fixedly connected to the inner wall of the positioning tube (201), and the other end of the connecting spring (202) is fixedly connected to the top of the connecting tube (204). The outer walls of the connecting tube (204) and the baffle (206) are both slidably connected to the inner wall of the positioning tube (201).

4. The cell freezing bag suitable for exhausting the cell mixture according to claim 1, characterized in that: The bottom end of the connecting tube (204) is provided with an inclined surface, and the outer wall of the extrusion plate (211) is in contact with the bottom end of the connecting tube (204).

5. The cell freezing bag suitable for exhausting the cell mixture according to claim 1, characterized in that: The top end of the positioning tube (201) is fixedly connected to the bottom end of the bag body (1), and the outer wall of the extrusion plate (211) is rotatably connected to the inner wall of the positioning tube (201).

6. The cell freezing bag suitable for exhausting the cell mixture according to claim 1, characterized in that: The dustproof mechanism (3) comprises a dustproof ring (301), the front end of the positioning tube (201) is fixedly connected to a positioning block (304), and the inner wall of the dustproof ring (301) is elastically connected to a socket (303) via a return spring (302).

7. The cell freezing bag suitable for exhausting the cell mixture according to claim 6, characterized in that: The inner side wall of the dustproof ring (301) is slidably connected to the outer wall of the positioning tube (201).

8. The cell freezing bag suitable for exhausting the cell mixture according to claim 6, characterized in that: One end of the return spring (302) is fixedly connected to the outer wall of the socket (303), and the other end of the return spring (302) is fixedly connected to the inner wall of the dustproof ring (301). The outer wall of the socket (303) is slidably connected to the inner wall of the dustproof ring (301), and the outer wall of the socket (303) is plugged into the inner wall of the positioning block (304).

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