Low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity

Abstract

The utility model discloses a low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity, which comprises a hydrogel layer, a hydrochloric acid aminolevulinic acid bulk layer, a treatment piece and a support fixing piece, a high-precision temperature sensor is arranged in the hydrogel layer, the hydrochloric acid aminolevulinic acid bulk layer is arranged at the bottom of the hydrogel layer, and the support fixing piece is arranged at the bottom of the hydrogel layer. The treatment piece comprises a red light generator, a light intensity adjusting chip is installed in the red light generator, and the red light generator, the temperature sensor and the light intensity adjusting chip are in electric signal transmission connection; and the supporting and fixing piece is used for suspending and fixing the red light generator above the skin wound. According to the treatment device, the ALA photodynamic treatment process is simplified, an individualized treatment device is formed, the temperature of the wound surface is monitored in real time through the temperature sensor, the light intensity is adjusted, long-term safety and effectiveness are achieved, and wound surface vascularization and granulation repair are promoted.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, and in particular to a low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity. Background Art

[0002] The skin is the largest organ in the human body, protecting the body from various external factors. Once damaged and infected by external microorganisms, it may develop into a chronic wound that is difficult to heal. After clearing the infection, the healing of chronic wounds takes 1-2 weeks to promote blood vessel formation and granulation repair.

[0003] At present, the commonly used clinical method is to use negative pressure drainage devices, but this treatment requires patients to stay in hospital for a long time and costs thousands to tens of thousands of yuan, especially for some small and medium-sized wounds. The cost-effectiveness of hospitalization is low, resulting in great economic and time losses. The conventional treatment of ALA is to kill bacteria by generating a large amount of ROS through high-intensity light, while low-dose photodynamic therapy has not yet been achieved in clinical practice. Based on this, we tried to design a low-efficiency photodynamic hydrogel treatment device that can automatically adjust the light intensity. Utility Model Content

[0004] In view of the shortcomings of the prior art, the utility model proposes a low-efficiency photodynamic hydrogel treatment device that can automatically adjust the light intensity, so as to solve the problem that negative pressure drainage device treatment requires patients to be hospitalized for a long time, resulting in great economic and time losses.

[0005] In order to solve the above technical problems, the technical solution adopted by the utility model is:

[0006] A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity, comprising:

[0007] A hydrogel layer, wherein a high-precision temperature sensor is provided inside the hydrogel layer;

[0008] An aminolevulinic acid hydrochloride dispersion layer, wherein the aminolevulinic acid hydrochloride dispersion layer is arranged at the bottom of the hydrogel layer;

[0009] A treatment element, the treatment element comprising a red light generator, a light intensity adjustment chip installed in the red light generator, and an electrical signal transmission connection between the red light generator, the temperature sensor and the light intensity adjustment chip; and

[0010] A supporting fixture is used to suspend and fix the red light generator above the skin wound surface.

[0011] The above-mentioned low-efficiency photodynamic hydrogel treatment device that can automatically adjust the light intensity, forms an aminolevulinic acid hydrochloride solution by spreading aminolevulinic acid hydrochloride on the wound surface, and then spreads a layer of hydrogel formed by anionic polyacrylamide on the aminolevulinic acid hydrochloride. Thereafter, a red light generator is suspended above the wound surface through a supporting fixture, and red light is emitted by the red light generator to stimulate the aminolevulinic acid hydrochloride liquid to exert its properties, thereby performing ALA-PDT treatment.

[0012] Furthermore, the hydrogel layer is made of a hydrogel formed by anionic polyacrylamide, and the aminolevulinic acid hydrochloride powder layer is made of aminolevulinic acid hydrochloride powder.

[0013] Furthermore, two temperature sensors are provided, and the two temperature sensors are arranged inside the hydrogel layer at intervals.

[0014] Furthermore, the supporting fixing member includes a storage frame, a bottom frame is fixedly provided at the bottom of the storage frame, a cross bar is fixed on both sides of the storage frame, a sliding sleeve is provided on the outer sliding sleeve of the cross bar, one end of the sliding sleeve is slidably connected to the vertical bar, a first locking bolt is provided on the top outer wall of one end of the sliding sleeve, the end thread of the first locking bolt penetrates and extends to the inside of the sliding sleeve and can abut against the outer wall of the cross bar, a first avoidance groove is provided on the top of the cross bar along the length direction, and a second avoidance groove connected to the first avoidance groove is provided on the length direction of the cross bar, a second locking bolt is provided on the outer wall of the other end of the sliding sleeve, the end thread of the second locking bolt penetrates the sliding sleeve and slides through the second avoidance groove to extend to the inside of the first avoidance groove and can abut against the outer wall of the vertical bar.

[0015] Furthermore, a bottom plate is fixedly mounted on the bottom of the two vertical rods.

[0016] Furthermore, two opposite side walls in the storage frame are provided with tightening blocks, and the sides of the two tightening blocks facing away from each other are provided with accommodating grooves. Springs are fixed in the two accommodating grooves, and the ends of the springs extending to the accommodating grooves are fixedly connected to the inner wall of the storage frame.

[0017] Furthermore, two opposite side surfaces at the tops of the two abutting blocks are both inclined surfaces, and the two inclined surfaces are symmetrically arranged.

[0018] The beneficial effects of the utility model are as follows: the low-efficiency photodynamic hydrogel treatment device that can automatically adjust the light intensity forms an aminolevulinic acid hydrochloride solution by spreading aminolevulinic acid hydrochloride on the wound surface, and then spreads a layer of hydrogel formed by anionic polyacrylamide on the aminolevulinic acid hydrochloride, and then suspends the red light generator above the wound surface through a supporting fixture, and the red light generator emits red light to stimulate the aminolevulinic acid hydrochloride liquid to exert its performance, and performs ALA-PDT treatment. The treatment device simplifies the ALA photodynamic therapy process and forms an individualized treatment device, which is convenient for patients to use the photodynamic device to treat the wound outside the hospital. The temperature of the wound is monitored in real time by a temperature sensor and the light intensity is adjusted to achieve long-term safety and effectiveness, so as to promote wound blood vessel formation and granulation repair, and reduce the time and energy spent in the hospital. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the specific implementation of the utility model, the following will briefly introduce the drawings required for use in the specific implementation. In all the drawings, each element or part is not necessarily drawn according to the actual scale.

[0020] Figure 1 It is the front view of the utility model;

[0021] Figure 2 It is a schematic diagram of the main structure of the connection between the horizontal rod, the vertical rod and the sliding sleeve;

[0022] Figure 3 A schematic diagram of the top view of the connection between the horizontal rod, the vertical rod and the sliding sleeve;

[0023] Figure 4 It is a cross-sectional view of the storage frame on the left side;

[0024] Reference numerals:

[0025] 10-hydrogel layer;

[0026] 20-aminolevulinic acid hydrochloride bulk layer;

[0027] 30- Temperature sensor;

[0028] 40- red light generator;

[0029] 50-support fixing member, 51-storage frame, 511-accommodation groove, 52-bottom frame, 53-cross bar, 531-first avoidance groove, 532-second avoidance groove, 54-vertical bar, 541-bottom plate, 55-sliding sleeve, 56-first locking bolt, 57-second locking bolt, 58-tightening block, 59-spring;

[0030] 61-skin, 62-wound. DETAILED DESCRIPTION

[0031] The following embodiments of the technical solution of the utility model are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the utility model, and are therefore only used as examples, and cannot be used to limit the protection scope of the utility model.

[0032] In the description of the present invention, it should be understood that the terms "center", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating directions or positional relationships, are based on the directions and positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the positions or elements referred to must have specific directions, be constructed and operated in a specific manner, and therefore should not be understood as limitations on the present invention.

[0033] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more features. In the description of the present utility model, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0034] See also Figure 1 ,in Figure 1 The reference numeral "61" indicates skin, and the reference numeral "62" indicates a wound surface. The utility model provides a low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity, comprising a hydrogel layer 10, an aminolevulinic acid hydrochloride dispersion layer 20, a treatment component, and a supporting fixture 50. A high-precision temperature sensor 30 is provided inside the hydrogel layer 10. The treatment component comprises a red light generator 40. The red light generator 40 can emit red light of a specific wavelength, thereby stimulating aminolevulinic acid hydrochloride to function easily and perform ALA-PDT treatment; the supporting fixture 50 is used to suspend and fix the red light generator 40 above the skin wound surface, so that the red light generator 40 can be stably placed, which is convenient for ALA-PDT treatment of the patient's skin wound surface. Among them, a high-precision temperature sensor 30 is provided inside the hydrogel layer 10 for sensing temperature changes, thereby facilitating the adjustment of the red light intensity emitted by the red light generator 40. Among them, the red light wavelength range required for ALA-PDT treatment is 620-640nm, which can stimulate the aminolevulinic acid hydrochloride solution to exert its efficacy.

[0035] Specifically, the aminolevulinic acid hydrochloride bulk layer 20 is arranged at the bottom of the hydrogel layer 10, and a high-precision temperature sensor 30 is arranged inside the hydrogel layer 10. The hydrogel layer 10 is made of a hydrogel formed by anionic polyacrylamide, and the hydrogel layer 10 is transparent; the aminolevulinic acid hydrochloride bulk layer 20 is made of aminolevulinic acid hydrochloride bulk. The hydrogel formed by anionic polyacrylamide has good heat conductivity, can better retain heat, and has good elasticity and high compressive strength, and can effectively protect the wound when attached to the skin wound.

[0036] A light intensity adjustment chip is installed in the red light generator 40, and the red light generator 40, the temperature sensor 30 and the light intensity adjustment chip are connected through electrical signal transmission. The red light generator 40 uses a light emitting diode (5MM red light 625-630NM), and the red light emitted by the light emitting diode includes red light with a wavelength range of 620-640nm; when in use, multiple light emitting diodes can be combined together to form the red light generator 40.

[0037] It is worth noting that the light emitting diode is a relatively low-power red light generator 40, which can produce ROS in a low-energy-efficiency manner and maintain the wound surface in a low-heat environment, thereby promoting blood vessel formation in the wound surface and promoting granulation repair, and is suitable for home use.

[0038] During use, when the hydrogel layer 10 is applied to the wound surface, the aminolevulinic acid hydrochloride powder will gradually dissolve in the liquid in the wound surface to form an aminolevulinic acid hydrochloride solution after contacting the wound surface. Then, the red light generator 40 is suspended above the wound surface through the support of the supporting fixture 50, and the red light generator 40 is started to emit red light to act on the aminolevulinic acid hydrochloride solution, thereby performing ALA-PDT treatment. During the treatment process, the temperature of the wound surface is monitored in real time by the temperature sensor 30, and the data is transmitted to the light intensity adjustment chip. If the temperature is too low, the red light intensity is increased, and if the temperature is too high, the red light intensity is reduced, thereby maintaining a long-term low-efficiency photodynamic therapy.

[0039] Preferably, two temperature sensors 30 are provided, and the two temperature sensors 30 are arranged at intervals inside the hydrogel layer 10. The arrangement of two temperature sensors 30 can more accurately monitor the temperature of the wound surface, thereby facilitating the adjustment of the red light intensity.

[0040] Please also read Figure 2 , Figure 3 and Figure 4In this embodiment, the support fixing member 50 includes a storage frame 51, a bottom frame 52 is fixedly provided at the bottom of the storage frame 51, and a cross bar 53 is fixed on both sides of the storage frame 51. A sliding sleeve 55 is provided on the outer side of the cross bar 53, and one end of the sliding sleeve 55 is slidably connected to a vertical rod 54. A first locking bolt 56 is provided on the outer wall of the top side of one end of the sliding sleeve 55. The end thread of the first locking bolt 56 extends through the inside of the sliding sleeve 55 and can abut against the outer wall of the cross bar 53. The top of the cross bar 53 is opened along the length direction. There is a first avoidance groove 531 passing through, the top of the vertical rod 54 passes through the other end of the sliding sleeve 55, and the vertical rod 54 is slidably arranged in the first avoidance groove 531, and the cross bar 53 is provided with a second avoidance groove 532 connected to the first avoidance groove 531 along the length direction, and a second locking bolt 57 is arranged on the outer wall of the other end of the sliding sleeve 55, and the end of the second locking bolt 57 is threaded through the sliding sleeve 55 and then slides through the second avoidance groove 532 to extend to the inside of the first avoidance groove 531 and can abut against the outer wall of the vertical rod 54. Among them, the bottom of the two vertical rods 54 are fixedly installed with a bottom plate 541, which can increase the contact area and enhance the stability of placement.

[0041] After the hydrogel layer 10 and the aminolevulinic acid hydrochloride loose layer 20 are applied to the wound surface, the red light generator 40 is placed in the storage frame 51, and the sliding sleeve 55 is pushed to move on the horizontal bar 53 according to the position of the wound surface on the patient's skin. At this time, the vertical rod 54 moves laterally in the first avoidance groove 531, so that the two vertical rods 54 are respectively located on both sides of the wound surface, and the first locking bolt 56 is tightened to fix the position of the sliding sleeve 55 on the horizontal bar 53 at this time; the sliding sleeve 55 is pushed to move downward along the vertical rod 54, so that the red light generator 40 drops above the wound surface, and then the second locking bolt 57 is tightened to fix the height position of the sliding sleeve 55 at this time. At this time, the gap between the red light generator 40 and the wound surface is smaller.

[0042] Preferably, the two opposite side walls in the storage frame 51 are provided with abutting blocks 58, and the sides of the two abutting blocks 58 facing away from each other are provided with receiving grooves 511, and springs 59 are fixedly provided in the two receiving grooves 511. The ends of the springs 59 extending to the receiving grooves 511 are fixedly connected to the inner wall of the storage frame 51, and the bottom of the abutting blocks 58 can slide on the bottom frame 52. When the red light generator 40 is placed in the storage frame 51, the springs 59 are in a contracted state, and the restoring elastic force of the springs 59 is used to make the abutting blocks 58 press against the outer wall of the red light generator 40, so as to prevent the red light generator 40 from shaking in the storage frame 51.

[0043] Preferably, the two opposite side surfaces at the top of the two clamping blocks 58 are both inclined surfaces, and the two inclined surfaces are symmetrically arranged, so that the red light generator 40 can easily move down along the inclined surfaces into the storage frame 51. At the same time, the red light generator 40 will also use the bottom to push the two clamping blocks 58 to move, so that the two clamping blocks 58 can be clamped on the red light generator 40.

[0044] The working principle of the utility model is as follows: when in use, the wound is first cleaned, and then physiological saline is dripped into the wound surface, and then aminolevulinic acid hydrochloride powder is applied to the wound surface, and then the hydrogel formed by anionic polyacrylamide is applied to the surface of the aminolevulinic acid hydrochloride powder, and two high-precision temperature sensors 30 are embedded in the hydrogel layer 10; at this time, the aminolevulinic acid hydrochloride powder gradually dissolves in the wound surface after contacting the wound surface to form aminolevulinic acid hydrochloride liquid; then the red light generator 40 is placed in the storage frame 51 and fixed, and the position of the sliding sleeve 55 is adjusted so that the bottom of the red light generator 40 is suspended above the wound surface, and the red light generator 40 is started to emit red light of a specific wavelength, so that the red light excites the aminolevulinic acid hydrochloride liquid to exert its performance, and ALA-PDT treatment is performed, and the red light treatment time is 4-5 hours.

[0045] The beneficial effects of the utility model are as follows: the low-efficiency photodynamic hydrogel treatment device that can automatically adjust the light intensity forms an aminolevulinic acid hydrochloride solution by spreading aminolevulinic acid hydrochloride on the wound surface, and then spreads a layer of hydrogel formed by anionic polyacrylamide on the aminolevulinic acid hydrochloride, and then suspends the red light generator 40 above the wound surface through the support fixture 50, and emits red light through the red light generator 40 to stimulate the aminolevulinic acid hydrochloride liquid to exert its performance, and perform ALA-PDT treatment. The treatment device simplifies the ALA photodynamic treatment process and forms an individualized treatment device, which is convenient for patients to use the photodynamic device to treat the wound surface outside the hospital. The temperature of the wound surface is monitored in real time by the temperature sensor 30 and the light intensity is adjusted to achieve long-term safety and effectiveness, so as to promote the formation of blood vessels and granulation repair on the wound surface, and reduce the time and energy spent in the hospital.

[0046] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and specification of the present invention.

Claims

1. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity, characterized in that: include: A hydrogel layer, wherein a high-precision temperature sensor is provided inside the hydrogel layer; An aminolevulinic acid hydrochloride bulk layer, wherein the aminolevulinic acid hydrochloride bulk layer is disposed at the bottom of the hydrogel layer; A treatment element, the treatment element comprising a red light generator, a light intensity adjustment chip installed in the red light generator, and an electrical signal transmission connection between the red light generator, the temperature sensor and the light intensity adjustment chip; and A supporting fixture is used to suspend and fix the red light generator above the skin wound surface.

2. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 1, characterized in that: The hydrogel layer is made of hydrogel formed by anionic polyacrylamide, and the aminolevulinic acid hydrochloride powder layer is made of aminolevulinic acid hydrochloride powder.

3. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 2, characterized in that: There are two temperature sensors, which are spaced apart inside the hydrogel layer.

4. The low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 1, characterized in that: The support fixing member includes a storage frame, a bottom frame is fixedly provided at the bottom of the storage frame, a cross bar is fixed on both sides of the storage frame, a sliding sleeve is provided on the outer sliding sleeve of the cross bar, one end of the sliding sleeve is slidably connected to the vertical rod, a first locking bolt is provided on the top outer wall of one end of the sliding sleeve, the end thread of the first locking bolt penetrates and extends into the interior of the sliding sleeve and can abut against the outer wall of the cross bar, a first avoidance groove is provided at the top of the cross bar along the length direction, and a second avoidance groove connected with the first avoidance groove is provided along the length direction, and a second locking bolt is provided on the outer wall of the other end of the sliding sleeve, the end thread of the second locking bolt penetrates the sliding sleeve and slides through the second avoidance groove to extend into the interior of the first avoidance groove and can abut against the outer wall of the vertical rod.

5. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 4, characterized in that: Bottom plates are fixedly mounted on the bottoms of the two vertical rods.

6. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 5, characterized in that: The two opposite side walls in the storage frame are provided with tightening blocks, and the sides of the two tightening blocks facing away from each other are provided with accommodating grooves. Springs are fixedly provided in the two accommodating grooves, and the ends of the springs extending to the accommodating grooves are fixedly connected to the inner wall of the storage frame.

7. A low-efficiency photodynamic hydrogel treatment device capable of automatically adjusting light intensity according to claim 6, characterized in that: The two opposite side surfaces of the tops of the two abutting blocks are both inclined surfaces, and the two inclined surfaces are symmetrically arranged.

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